• Title/Summary/Keyword: R&D Test Process

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SAL 10-6 and Cytotoxicity of Sanitary Aid Products Utilizing Gamma Sterilization Technology (감마선 멸균기술을 이용한 의약외품의 무균보증수준(SAL 10-6) 확보 및 세포독성 평가)

  • Kim, Kwang Hoon;Eom, Yong Woon;Lee, Hoo Chul;Park, Sung Hyun;Kim, Soo Jin;Kim, Kwan Soo;Park, Soon Youn;Jeong, Ill Yun
    • Journal of Radiation Industry
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    • v.8 no.2
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    • pp.133-140
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    • 2014
  • The sterilization of health care products is widely used to choose conventional Ethylene Oxide gas sterilization in South Korea. But the method has brought serious issues because of the toxic residual gas and global warming of $CO_2$ evacuation after the sterilization process. This study is carried out to confirm the application possibility of gamma sterilization instead of Ethylene Oxide in sanitary aid products. Four kinds of products (gauze, menstrual pad, bandage, menstrual tampon) were treated with gamma irradiation of 15 kGy, then analyzed the achievement of the sterility assurance level (SAL) $10^{-6}$ through BI test. The cytotoxicity of accelerated samples of 6 months elapse evaluated by means of colony forming rate at various concentration of the extracts. pH and UV measurements at extract concentrations were tested according to the MFDS (Ministry of food & drug safety) guideline to verify a stability & safety of product sterilized. The results revealed that the extracts did not show any significant changes in cytoxicity assay as well as pH and UV values by gamma sterilization. All extract concentration was observed high cell viability, pH and UV values were calculated within the acceptable range prescribed by the guideline. It indicates that gamma sterilization could effectively substitute for conventional sterilization such as Ethylene Oxide sterilization in the sanitary aid products.

The Role of Open Business Model in Technology Commercialization

  • Park, Hyo J.;Shin, Wan S.;Ju, Yong J.
    • Journal of Korean Society for Quality Management
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    • v.42 no.3
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    • pp.477-496
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    • 2014
  • Purpose: This paper has examined the impact of open innovation business model in technology commercialization with the data from 30 companies of manufacturing firms in South Korea. Methods: The findings provide support for distinguishing five hypotheses relating to development time, IP management, sales, firm size and R&D intensity. To test the hypotheses, data were collected using via e-mail and fax. Small and medium-sized (less than 300 employees) and large industrial firms were chosen for this study. Results: The result shows that openness in its business model is positively associated with successful technology commercialization. Conclusion: The major findings and the implications are: First, as the business model gets more open, development period of technology will be more favorable which gets benefit from rising costs of innovation. Second, as the business model gets more open, large portion of sales are created from new products. Thus, the problem of shorter product life in the market which affects large portion of market revenue can be solved through an open business model. Third, in general, R&D intensity, firm size and the level of IP management affect determination of business model types. The findings also suggest that companies need to increasingly address their external technology exploitation process instead of focusing on their internal innovation processes.

Study on Analysis Process for Slip Torque Design Control of Impact Hammer Drills (임팩트햄머 드릴의 슬립토크 설계 제어를 위한 분석 프로세스 고찰)

  • Kim, Seung Hyeon;Kwon, Sang Youp;Ko, Dong Shin;Hur, Deog Jae;Dong, Kwang Ho
    • Journal of the Korean Society for Precision Engineering
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    • v.33 no.5
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    • pp.401-407
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    • 2016
  • This paper describes the derivation methodology of the working torque predictive model that can be used in the initial design stages of the impact hammer tool. The working torque control mechanism is designed, taking into account various factors, such as the force of the spring and friction. Firstly, the analysis dynamic model for working environments was modeled as an additional bush and spring, and verified by comparing the test results of the working torque. Secondly, the main performance parameters of the working torque were theoretically defined by analyzing the operating mechanism. The equation to predict the working torque was derived using the dynamic analysis results according to the value changes of the parameters. The prediction equation of the working torque was validated by comparing the predicted results with the experimental data. The error difference between the experimental data and the predictive model results was found to be 8.62%.

Microcomputer FEM Analysis of Soil Cutting Process

  • Shen, J.;Kushwaha, R.L.
    • Proceedings of the Korean Society for Agricultural Machinery Conference
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    • 1993.10a
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    • pp.1063-1072
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    • 1993
  • Current finite element analysis programs for soil cutting process with tillage tools require mainframe computers. Several special treatments in developing a microcomputer FEM program were introduced to increase the capacity for solving large problems and reducing the total time cost. The program was evaluated by solving one 3-D example on a 489 microcomputer. The results showed a close agreement with the laboratory soil bin test.

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Lateral Control Methods for Roll-to-roll Printed Electronics (롤투롤 인쇄전자용 폭방향 제어 기법)

  • Ho, Thanh-Tam;Shin, Hyeun-Hun;Lee, Sang-Yoon
    • Journal of Institute of Control, Robotics and Systems
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    • v.15 no.8
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    • pp.792-797
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    • 2009
  • This paper presents the evaluation of PID and fuzzy control logic for the lateral position control of a moving web in roll-to-roll (R2R) printed electronics. In addition, we report the implementation of computer simulation software that enables us to develop the control logic in a graphic user interface and to test the controller performance in 3D dynamic environment. A mathematical model of the web dynamics is described first to explain the lateral motion of a moving web. Based on the model, PID and fuzzy controllers are designed, and embedded in the simulation software. Under the simulation conditions for fabricating RFID antenna by R2R printing, the results indicate that the fuzzy controller shows a better performance and can be more suitable for R2R multi-layer printed electronics.

Finite Element Analysis of an Agricultural Tractor Cabin based on the OECD Standard(code 4) (OECD규정(제4항)에 기초한 농업용 트랙터 캐빈의 유한요소 해석)

  • 하창욱;김현진;구남서;권영두
    • Journal of Biosystems Engineering
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    • v.28 no.4
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    • pp.305-314
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    • 2003
  • The ROPS of an agricultural tractor is designed to protect its driver when the tractor overturns. Although the current OECD tests to determine whether the ROPS meets the requirements of the OECD regulation are desirable, they need long time to test. We experimental time and effort by using CAE. We conducted a finite element analysis for the ROPS design of a Dae-Dong tractor cabin in an attempt to reduce the design and manufacturing time. This study shows the interpretative skill using MARC(v.2000) for designing ROPS and difference between the results of testing and FEA. Design process is generally divided into two phases: a concept and a detail design. The concept design uses simple analysis to predict structural behavior, whereas the detail design involves a finite element analysis performed by the results of the concept design. This study focused on the detail design and used Patran(v.2000r2) and MARC(v.2000) of the MSC software corporation. The model consisted of 4812 elements and 4582 nodes. Four tests. specified in the OECD standards, were performed: (1) longitudinal loading test (2) rear crushing test (3) side loading test (4), and front crushing test. Independent analyses were also performed for each test, along with a sequential analysis. When compared, the results of the independent and sequential analyses were found to be similar to the test results.

Noise Source Identification of a Starter Motor using DOE (Design of Experiments: A Case Study) (실험계획법을 이용한 차량용 시동장치의 소음원 규명 및 개선 사례에 관한 연구)

  • Park, Soon-Sik;Lim, Byoung-Duk
    • Transactions of the Korean Society of Automotive Engineers
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    • v.16 no.1
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    • pp.106-113
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    • 2008
  • The starter motor noise is usually well identified by the customers since it is operated while the engine is quiet, and leaves distinct impressions of the vehicle. In this study the design of experiments(DOE) was applied to the identification of the noise sources of direct drive starter motor since this process usually requires lengthy analysis and elaborate experiments. In the first stage of the test, five controllable factors(alignment and dynamic unbalance of armature, tightening torques of T/bolt and center bracket bolt, and alignment of the center bracket-yoke-rear bracket), excluding static unbalance, are sorted out of all possible factors. Test results showed that the dynamic unbalance and misalignment of armature are the major factors. However, the error level of the first test was relatively high, indicating that there might be some missing major factors. In the second stage test the results showed that both static and dynamic unbalances are the dominant factors contributing to more than 80% of the overall noise, while the misalignment contributes around 12%. Error of the second test was about 4% that could be considered satisfactory. The noise level of the optimal product was predicted to be reduced by 19dBA, and verification test showed the average noise reduction of 16.8dBA with the standard deviation of 3.2dBA, and proved the usefulness of the whole DOE process.

Wafer-Level Three-Dimensional Monolithic Integration for Intelligent Wireless Terminals

  • Gutmann, R.J.;Zeng, A.Y.;Devarajan, S.;Lu, J.Q.;Rose, K.
    • JSTS:Journal of Semiconductor Technology and Science
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    • v.4 no.3
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    • pp.196-203
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    • 2004
  • A three-dimensional (3D) IC technology platform is presented for high-performance, low-cost heterogeneous integration of silicon ICs. The platform uses dielectric adhesive bonding of fully-processed wafer-to-wafer aligned ICs, followed by a three-step thinning process and copper damascene patterning to form inter-wafer interconnects. Daisy-chain inter-wafer via test structures and compatibility of the process steps with 130 nm CMOS sal devices and circuits indicate the viability of the process flow. Such 3D integration with through-die vias enables high functionality in intelligent wireless terminals, as vertical integration of processor, large memory, image sensors and RF/microwave transceivers can be achieved with silicon-based ICs (Si CMOS and/or SiGe BiCMOS). Two examples of such capability are highlighted: memory-intensive Si CMOS digital processors with large L2 caches and SiGe BiCMOS pipelined A/D converters. A comparison of wafer-level 3D integration 'lith system-on-a-chip (SoC) and system-in-a-package (SiP) implementations is presented.

A Study on Failure Modes of Type4 Composite Pressure Cylinders according to Shapes of Domes (Type4 복합재 용기의 돔 형상에 따른 파열형태에 관한 연구)

  • Cho, Sungmin;Kim, Kwang Seok;Cho, Min-sik;Lee, Sun-kyu;Lee, Seung-kuk;Lyu, Sung-Ki
    • Journal of the Korean Society of Manufacturing Process Engineers
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    • v.16 no.5
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    • pp.13-18
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    • 2017
  • In this work the augmented safety of Type 4 composite vessel in accordance with uniform-stress design has been demonstrated through a series of burst tests and structural analyses. For this end, three sample vessels were used: (1) designed as guided by the isotensoid dome theory (called iso-dome cylinder); (2) with dome longer compared to uniform-stress design (called prolate cylinder); and (3) with dome wider than uniform-stress design (called oblate cylinder). Structural analyses have been performed using ABAQUS finite element code based on the periodic symmetry to circumferential direction. As a result, the maximum stresses are induced around the bodies of all three cylinders. However, the analyses, with the assumption of possible defect demonstrate that the maximum stresses are induced around the dome knuckles for the prolate and the oblate cylinders. The results of the burst tests for the three cylinders show that the burst initiates from the cylinder body of the iso-dome cylinder and from the dome knuckles of the prolate and the oblate cylinders. Finally, it is recommended that, to comply with DOT CFFC 2007, the dome shape should be designed and fabricated as guided by the isotensoid dome theory.

MODAL TESTING AND MODEL UPDATING OF A REAL SCALE NUCLEAR FUEL ROD

  • Park, Nam-Gyu;Rhee, Hui-Nam;Moon, Hoy-Ik;Jang, Young-Ki;Jeon, Sang-Youn;Kim, Jae-Ik
    • Nuclear Engineering and Technology
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    • v.41 no.6
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    • pp.821-830
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    • 2009
  • In this paper, modal testing and finite element modeling results to identify the modal parameters of a nuclear fuel rod as well as its cladding tube are discussed. A vertically standing full-size cladding tube and a fuel rod with lead pellets were used in the modal testing. As excessive flow-induced vibration causes a failure in fuel rods, such as fretting wear, the vibration level of fuel rods should be low enough to prevent failure of these components. Because vibration amplitude can be estimated based on the modal parameters, the dynamic characteristics must be determined during the design process. Therefore, finite element models are developed based on the test results. The effect of a lumped mass attached to a cladding tube model was identified during the finite element model optimization process. Unlike a cladding tube model, the density of a fuel rod with pellets cannot be determined in a straightforward manner because pellets do not move in the same phase with the cladding tube motion. The density of a fuel rod with lead pellets was determined by comparing natural frequency ratio between the cladding tube and the rod. Thus, an improved fuel rod finite element model was developed based on the updated cladding tube model and an estimated fuel rod density considering the lead pellets. It is shown that the entire pellet mass does not contribute to the fuel rod dynamics; rather, they are only partially responsible for the fuel rod dynamic behavior.