• Biotechnology and Bioprocess Engineering:BBE
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• v.5 no.5
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• pp.340-344
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• 2000

Microbial oxidation of D-sorbitol to L-sorbose by Acetobacter suboxydans is of commercial importance since it is the only biochemical process in vitamin C synthesis. The main bottleneck in the batch oxidation of sorbitol to sorbose is that the process is severely inhibited by sorbitol. Suitable fed-batch fermentation designs can eliminate the inherent substrate inhibition and improve sorbose productivity. Fed-batch sorbose fermentations were conducted by using two nutrient feeding strategies. For fed-batch fermentation with pulse feeding, highly concentrated sorbitor (600g/L) along with other nutrients were fed intermittently in four pulses of 0.5 liter in response to the increased DO signal. The fed-batch fermentation was over in 24h with a sorbose productivity of 13.40g/L/h and a final sorbose concentration of 320.48g/L. On the other hand, in fed-batch fermentation with multiple feeds, two pulse feeds of 0.5 liter nutrient medium containing 600g/L sorbitol was followed by the addition of 1.5 liter nutrient medium containing 600g/L sorbitol at a constant feed rate of 0.36L/h till the full working capacity of the reactor. The fermentation was completed in 24h with an enhanced sorbose productivity of 15.09g/L/h and a sorbose concentration of 332.60g/L. The sorbose concentration and productivity obtained by multiple feeding of nutrients was found to be higher than that obtained by pulse feeding and was therefore a better strategy for fed-batch sorbose fermentation.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.9 no.4
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• pp.1086-1094
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• 2008

Today's small and medium-sized enterprises in technology development for future industrial growth engine. In addition evaluation of the technological competitiveness of companies and countries for R&D investment as a significant item evaluated constantly expanding, he said. However, R&D productivity to properly measure and assess the companies rarely. This paper examines the existing technology, technology assessment, the study's limitations, the small and medium-sized companies to complement the U-IT TE and PSMP Model suggested by the design environment, and technology-related companies in the technology, the ability to comprehensively assess and as a tool to leverage, technical analysis and quantitative evaluation and production from the completion of the Process Model, presented want to formalize.

• Journal of the Semiconductor & Display Technology
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• v.7 no.3
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• pp.11-16
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• 2008

The authors investigated an overhead shuttle (OHS) system for automatic transferring the liquid crystal display (LCD) panels. The constructed tracks of OHS system include the linear and curve regions and have been installed on the ceiling to transfer the cassette of LCD glass along the closed-loop and open-loop tracks. In this study, the OHS system was implemented by a proposed linear motor to solve encoder installation and the system cost problems of the long distance transfer system. In addition, we utilized a new algorithm of the position detection and a new control algorithm for driving linear motor. The newly developed control algorithm was demonstrated from both a computer simulation and an experimentation, indicating that the highly reliable and speedy transfer system can enhance the LCD panel productivity of commercial OHS system.

• Journal of the Korean Society for Precision Engineering
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• v.31 no.9
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• pp.799-804
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• 2014

Hard turning is a machining process for hardened materials with high surface quality so that grinding process can be eliminated. Therefore, the hard turning is capable of reducing machining time and improving productivity. In this study, hardened AISI4140 (high-carbon chromium steel) that has excellent yield strength, toughness and wear resistance was finish turned using CBN tools. Wear characteristics of CBN tool was analyzed in dry and MQL mixed with nano-particle (Nano-MQL). The dominant fracture mechanism of CBN tool is diffusion and dissolution wear on the rake surface resulting in thinner cutting edge. Abrasive wear by hard inclusion in AISI4140 was dominant on the flank surface. Nano-MQL reduced tool wear comparing with the dry machining but chip evacuation should be considered. A cryogenically treated tool showed promising result in tool wear.

• Journal of Animal Environmental Science
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• v.20 no.2
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• pp.49-56
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• 2014

The climate of the earth is expected to change rapidly and continuously. Despite climate change is expected to impact on productivity of crop and livestock, a study for adaptation and impact of livestock to global warming is not enough. This study was performed to develop a method to evaluate the effects of heat stress on dairy cattle. Feedlot environment and health status of livestock were measured through an infrared thermography camera and a temperature-humidity sensor. Environmental factors such as temperature and humidity were measured to calculate the Temperature humidity index (THI). The change of the milk yield was similar to THI data pattern, suggesting that THI might play an important role to predict the effect of climate change on dairy cattle. THI data would be useful to predict long-term climate change effects on dairy cattle with RCP8.5 scenario.

• Archives of Pharmacal Research
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• v.28 no.3
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• pp.325-329
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• 2005

The hepatoprotective activity of lactic acid bacteria (Lactobacillus brevis HY7401, Lactobacillus acidophilus CSG and Bifidobacterium longum HY8001), which inhibited $\beta$-glucuronidase productivity of intestinal microflora, on t-BHP- or CCl$_4$-induced hepatotoxicity of mice were evaluated. These oral administration of lactic acid bacteria lowered $\beta$-glucuronidase production of intestinal microflora as well as Escherichia coli HGU-3. When lactic acid bacteria at a dose of 0.5 or 2 g (wet weight)/kg was orally administered on CCl$_4$-induced liver injury in mice, these bacteria significantly inhibited the increase of plasma alanine transferase and aspartate transferase activities by $17-57\%$ and $57-66\%$ of the $CCI_4$ control group, respectively. These lactic acid bacteria also showed the potent hepatoprotective effect against t-BHP-induced liver injury in mice. The inhibitory effects of these lactic acid bacteria were more potent than that of dimethyl diphenyl bicarboxylate (DDB), which have been used as a commercial hepatoprotective agent. Among these lactic acid bacteria, L. acidophilus CSG exhibited the most potent hepatoprotective effect. Based on these findings, we insist that an inhibitor of $\beta$-glucuronidase production in intestine, such as lactic acid bacteria, may be hepatoprotective.

• Journal of Welding and Joining
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• v.31 no.6
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• pp.27-31
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• 2013

Magnesium alloy is used on parts of aircraft and electronic equipment because of the highest specific strength among the common metal materials. Recently, studies about appling magnesium alloy sheet to automotive bodies are on the increase rapidly. For application to automotive bodies, researches about characteristics of resistance spot welding of magnesium alloy sheet are essential. Magnesium alloy has low boiling point, so getting sound bead shape is difficult when appling varies welding processes. Resistance spot welding is also particular about setting optimum welding conditions because of spatter generation, pores and cracks occurrence in nugget. And life of electrodes is very short because of alloying with copper that main material of electrodes. This requires frequent dressing and replacement of electrodes and decrease in productivity of resistance spot welding on magnesium alloy. Therefore in this study, for effective analysis of changes in tensile shear load and nugget size during electrode life test, evaluate detail characteristics of resistance spot welding on magnesium alloy sheet using dome type electrode.

• Journal of Ecology and Environment
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• v.31 no.2
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• pp.125-129
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• 2008

To predict Daphnia secondary productivity along a trophic gradient indexed as total phosphorus (TP) concentration, we estimated energy transfer efficiencies from food quality for Daphnia such as eicosa-pentaenoic acid (EPA) or docosahexaenoic acid (DHA) content. Eleven flow-through Daphnia magna growth experiments were conducted with seston from 9 lakes, ponds and river waters. Primary productivities were estimated from food supply rates in the flow-through experiments, producing energy transfer efficiencies from seston to D. magna. We found DHA content was the best predictor of energy transfer efficiencies among the essential fatty acids. An asymptotic saturation model explained 79.6% of the variability In energy transfer efficiencies. Based on empirical data in this study and empirical models from literature, we predict that Daphnia productivity would peak in mesotrophic systems by decreasing food quality and Increasing food quantity along trophic gradient.

• Journal of Construction Engineering and Project Management
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• v.4 no.1
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• pp.45-50
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• 2014

Productivity analysis is the most important and significant method for evaluating management and engineering performance during whole project stage. However, it is very difficult in developing qualitative index to construction industry comparing to other industries. Therefore, analytical hierarchy process (AHP) is one of the methods for overcoming these limitations by checking consistency index using duality comparison. In this study, it is scraped up an application plan and selection for innovative tools by analyzing survey results on tool users and site managers with respect to using Modified-AHP performance measurement method.

• Design & Manufacturing
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• v.2 no.6
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• pp.17-22
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• 2008

Recently, the demand of high-productivity injection mold increases since the consumption of packaging grows in the world. Stack mold is composed of more than two molds and it has very high productivity and economic efficiency. In advanced country, stack mold which has was developed already but, in occasion of domestic mold industry, there is no study of stack mold. In this study, die and mold of in-mold labeling was developed for securing the technique of manufacturing high-productivity mold.