• Journal of Periodontal and Implant Science
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• 제25권3호
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• pp.603-613
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• 1995

The purpose of this investigation was to evaluate on the biodegradability, biocompatibility and tissue regenerative capacity of synthetic bioabsorbable membranes in beagle dogs. For animal study, 9 adult beagle dogs were used to examination, on the surgical implantation of membranes and histological analysis. In each animal, the 3rd and 4th premolars of the both sides of the mandible were selected as test teeth. Two types of bioresorbable membranes including "Guidor membrane", "S-membranes" were used to examining for biological activity, and also Gore-tex membranes was used for positive control. Surgically created defects were made in 2 premolars of both sides of the mandible at $3{\times}4mm^2$ in size and tested membranes were implanted in the defected area. A plaque control regimen was instituted with daily tooth brushing with a 0.1% chlorhexidine digluconate during experimental periods. All the experimental animals were sacrificed after 2, 4, and 8 weeks from surgery and undecalcified slides were prepared using the "sawing and grinding" technique described by Donath and Breuner". In biodegradability, all the membranes were started their biodegradation from two weeks after implantation and gradually demolished of their frame morphology from eight weeks. However, demolition of membranes in 8 weeks after implantation was highest in Guidor membranes and followed by S-membranes. Biocompatibilityof two kinds of biodegradable membranes including Guidor and S-mambrane were shown to be well tolerated to the surrounding tissue, and were minimal accumulation of inflammatory cell infiltration around the implanted membranes to compare with Gore-tex membrane. Regeneration of defected alveolar bone was initiated from two weeks of membrane implantation and new bone formation was gradually increased from that time. However, pattern of new bone formation on the defected areas of two kinds of biodegrable membranes was almost similar and quite competitive comparing with Gore-tex membrane. These results implicate that bioresorbable membranes should be highly useful tool for guided tissue regeneration of periodontal defects.

• Composites Research
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• 제29권2호
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• pp.45-52
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• 2016

An understanding of the failure mechanisms of the adhesive layer is decisive in interpreting the performance of a particular adhesive joint because the delamination is one of the most common failure modes of the laminated composites such as the fiber metal laminates. The interface between different materials, which is the case between the metal and the composite layers in this study, can be loaded through a combination of fracture modes. All loads can be decomposed into peel stresses, perpendicular to the interface, and two in-plane shear stresses, leading to three basic fracture mode I, II and III. To determine the load causing the delamination growth, the energy release rate should be identified in corresponding criterion involving the critical energy release rate ($G_C$) of the material. The critical energy release rate based on these three modes will be $G_{IC}$, $G_{IIC}$ and $G_{IIIC}$. In this study, to evaluate the fracture behaviors in the fracture mode I and II of the adhesive layer in fiber metal laminates, the double cantilever beam and the end-notched flexure tests were performed using the reference adhesive joints. Furthermore, it is confirmed that the experimental results of the adhesive fracture toughness can be applied by the comparison with the finite element analysis using cohesive zone model.

• Journal of Physiology & Pathology in Korean Medicine
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• 제17권3호
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• pp.719-727
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• 2003

Background and purpose: Hypertension and obesity has been implicated in the most important risk factors for stroke. The original finding that the G-protein beta3 subunit (GNB3) C825T allele associates with essential hypertension and obesity has been confirmed in several different populations. Hence, our objective was to determine whether the GNB3 C825T polymorphism predicts interindividual variation in stroke. Method: We recruited 361 stroke patients (cerebral infarction, n=278; intracerebral hemorrhage (ICH), n=83) and 199 healthy control subjects. Subjects were genotyped for GNB3 C825T mutation and findings were investigated for association with stroke. Result: The GNB3 T/T type was significantly associated with cerebral infarction prevalence (OR, 1.98; 95% Cl, 1.14-3.46; p=0.015). While, ICH was not found to be significantly associated with GNB3 T/T type (OR, 1.63; 95% ICH, 0.74-3.56; p=0.219). Similarly, no significant association was determined between GNB T/C type, and cerebral infarction (OR, 1.09; 95% Cl, 0.68-1.74; p=0.716), and ICH (OR, 1.14; 95% Cl, 0.59-2.21; p=0.697). Conclusion: In clinical characteristics, this study shows no differences among GNB3 genotypes, that are BMI, WH ratio. hypertension rate, and ischemic heart disease rate, total lipid level, triglycerides level, total cholesterol level, HDL cholesterol level, prothrombine time, with the exception of LDL cholesterol concentrations. However, our subjects showed an inverse relationship between LDL cholesterol level and the risk of cerebral infarction. We have shown that the GNB3 T/T genotype is strongly associated with cerebral infarction. (OR, 1.98; 95% Cl, 1.14-3.46; p=0.015).

• Journal of Korean Society of Coastal and Ocean Engineers
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• 제22권4호
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• pp.258-271
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• 2010

In order to figure out hydrodynamic and water quality changes after completion of dike construction of the Saemangeum, which behaves as a semi-enclosed estuarine lake, numerical simulations based on fine grid structure by using EFDC were intensively carried out. In this study some limitations of precedent study has been improved and gate operation were considered. Also 3 phases such as air-water-sediment interaction modeling was considered. It is clear that inner mixing of the Saemangeum is dominated by Mankyeong and Dongjin riverine discharges rather than the gate opening influence through the Lagrangian particle tracking simulations. Vertical DO structure after the dike completion shows steep gradient especially at Dongjin river estuary due to lessen of outer sea water exchange. Increasing SOD at stagnantly changed man-made reservoir might cause oxygen deficiency and accelerating degradation of water quality. According to TSI evaluation test representing eutrophication status, it shows high possibility of eutrophication along Mankyeong waterway in spite of dike completion, while the index is getting high after final closing along Dongjin waterway. Numerical tests with gate operations show significant differences in water quality. Thus it should be noted that proper gate operation plays a major role in preserving target water quality and management for inner development plan.

• The Journal of Engineering Geology
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• 제26권3호
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• pp.371-382
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• 2016

Saltwater intrusion in coastal regions can be detected by using numerous geochemical constituents in groundwater. However, insufficient numbers of groundwater data can often make us difficult to interpret saltwater intrusion. Probability statistics technique enables statistical prediction using a limited numbers of water quality data for a wider range and can make to effectively evaluate saltwater intrusion through a characterized distribution of probability. This study evaluated saltwater intrusion by applying probability statistics to the chemical constituents in groundwater, coastal discharge, and stream water in the coastal areas of Busan City. By the result of the study, it is proven that Na⁺, Mg²⁺, K⁺, SO₄²⁻, and Cl⁻, abundantly contained in seawater, are valuable indicators for evaluating saltwater intrusion. On the other hand, it is judged that Si⁴⁺, Fe²⁺, NO₃⁻, and PO₄³⁻, showing similar probability distribution in groundwater, coastal discharge, and stream water, are not appropriate indicators for the detection of saltwater intrusion.

• Journal of the Korean Wood Science and Technology
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• 제46권5호
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• pp.497-510
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• 2018

In this study, the decay resistance of larch wood, which was heat treated by superheated steam, was evaluated by the field decay test. During the field decay test of 12 months, non-treated wood has been severely damaged by termite, however, no visible damage has occurred in the preservative-treated wood and superheated steam heat-treated wood. Results of field decay test showed approximately 5% mass loss of the non-treated wood and the preservative-treated wood, and approximately 1% mass loss of the superheated steam heat-treated wood. After the field decay test for 12 months, the residual amount of preservatives remaining in the preservative-treated wood was lower than that before the field decay test. It was considered that the preservative was partially eluted during the field decay test, and the mass loss of the preservative-treated wood was thought to be similar to that of the non-treated wood. Through this study and additional long-term monitoring test, superheated steam heat treatment can be considered to be an environmental-friendly method to enhance the decay resistance of wood against rot fungi and/or insect without chemical treatment such as preservative injection.

• Food Science of Animal Resources
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• 제35권1호
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• pp.143-148
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• 2015

Yogurt powder is fermented milk processed in the form of dry yogurt, and has advantages such as stability, storability, convenience, and portability. China and Vietnam are important export target countries because of the increased demand for dairy products. Therefore, we surveyed dairy product standardization in order to establish an export strategy. Lactic acid bacteria counts are unregulated in Korea and Vietnam. In China, lactic acid bacteria counts are regulated at $1{\times}10^6$ colonyforming units (CFU)/mL and detected at $6.24{\pm}0.33\;Log\;CFU/mL$. All three countries have regulated standards for total bacterial counts. In China, total bacterial counts of milk powder are regulated to n=5, c=2, m=50,000, M=200,000 and detected at $6.02{\pm}0.12\;Log\;CFU/mL$, exceeding the acceptable level. Lactic acid bacterial counts appeared to exceed total bacterial counts. Coliform group counts, Staphylococcus aureus, Listeria monocytogenes, and Salmonella species were not detected. Acidity is not regulated in Korea and Vietnam. In China, acidity was regulated to over $70^{\circ}T$ and detected $352.38{\pm}10.24^{\circ}T$. pH is unregulated in all three countries. pH was compared to that of general fermented milk, which is 4.2, and that of the sample was $4.28{\pm}0.01$. Aflatoxin levels are not regulated in Korea and China. In Vietnam, aflatoxin level is regulated at 0.05 ppb. Therefore, all ingredients of the yogurt powder met the safety standards. This data obtained in this study can be used as the basic data in assessing the export quality of yogurt powder.

• KDI Journal of Economic Policy
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• 제26권2호
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• pp.63-104
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• 2004

Economists have long been involved in various studies, theoretical and empirical, on the economic gains from innovative activities and as their outcome, intellectual properties. In Korea, however, research in this field has experienced rather slow progress, partly due to the lack of data availability and the awareness of its importance. This study attempts to measure the economic impact of patents on market value of firms from a microeconomic point of view. Analyses are performed to examine the ex-ante market valuation of patent acquisition activities by investigating the effect of patent acquisitions on daily stock prices as well as on annual market values. The study on the effect of a disclosure of granted patents on daily stock prices reveals that the economic value of a firm's patent acquisition is fairly high. The study on listed firms also reveals that a firm's patent registration stock has a positive and statistically significant effect on its year-end market value. Therefore, it can be concluded that the analysis performed in this study supports the validity of Korea's current patent system. The result, however, does not guarantee the optimality of current system. Studies on various aspects of intellectual property should follow to shape the system into a socially optimal one.

• Journal of the Institute of Electronics Engineers of Korea SD
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• 제48권9호
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• pp.40-49
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• 2011

Integrating massive components and low-power policies have been actively investigated for system-on-chip designs. But in recent years, finding the optimal interconnection structure among heterogeneous components has emerged as a critical system design issue. Therefore, various simulation tools to model interconnection designs are being developed and performance evaluation of simulation is reflected in the real design. But most of the simulation environments employ traffic generation based on the mathematical probability functions, and such traffic generation cannot fully cover for various situations that may be occurred in the real system. Therefore, the demand for traffic pattern generation based on real applications is increasing. However, there have been few simulators that adopt application-specific traffic generators. This paper proposes a novel traffic generation method in simulating various interconnection structures for multi-processor system-on-chip design. The proposed traffic generation method can generate traffic patterns that can reflect the actual characteristics of the application and evaluate the performance of an interconnection structure under more realistic circumstance than traffic patterns using mathematical probability functions. By comparing the differences between the proposed method and the one based on mathematical probability functions, this paper shows advantages of the proposed traffic generation method.

• Journal of Bio-Environment Control
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• 제22권2호
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• pp.81-86
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• 2013

This experiment was carried out to select white asparagus varieties suitable for shading culture in greenhouse. Eight white and one green varieties were tested. Seeds were sown in 72-cell trays in a glasshouse on 24 Dec. 2008 and the seedlings were transplanted in a P.E house on 22 May 2009. Planting distances were 30 cm apart in a raw and 125 cm between the raws. For white asparagus production, small tunnel ($210cm{\times}160cm$) was established inside the P.E house, and covered with black and white P.E film (0.1 mm) on 5 March 2010. Days to sprouting took 5 days in 'Ravel' variety and took 16 to 18 days in 'Backlim', 'Horlim', 'Herkolim' varieties. The number of spear was highest in 'Ravel' with 6 and lowest in 'Backlim' with 3.7. The spear weight was heaviest in 'Herkolim' with 25.6 g and lightest in 'Ravel' with 15.6 g. The highest total yield was in 'Herkolim' with 296 kg/10a, followed by 'Super welcome' with 275 kg/10a and lowest in 'Rapsody' with 176 kg/10a. Marketable yields in 'Super welcome' and 'Herkolim' were 241 kg/10a and 239 kg/10a, respectively, and the yield was lowest in 'Rapsody' with 139 kg/10a. The L grade (over 20 g of spear weight) was highest in 'Herkolim'. Accordingly, 'Herkolim' was the most suitable white asparagus variety among the tested varieties for shading cultivation in greenhouse.