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검색결과 163건 처리시간 0.036초

Study of the structural damage identification method based on multi-mode information fusion

  • Liu, Tao;Li, AiQun;Ding, YouLiang;Zhao, DaLiang
    • Structural Engineering and Mechanics
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    • 제31권3호
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    • pp.333-347
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    • 2009
  • Due to structural complicacy, structural health monitoring for civil engineering needs more accurate and effectual methods of damage identification. This study aims to import multi-source information fusion (MSIF) into structural damage diagnosis to improve the validity of damage detection. Firstly, the essential theory and applied mathematic methods of MSIF are introduced. And then, the structural damage identification method based on multi-mode information fusion is put forward. Later, on the basis of a numerical simulation of a concrete continuous box beam bridge, it is obviously indicated that the improved modal strain energy method based on multi-mode information fusion has nicer sensitivity to structural initial damage and favorable robusticity to noise. Compared with the classical modal strain energy method, this damage identification method needs much less modal information to detect structural initial damage. When the noise intensity is less than or equal to 10%, this method can identify structural initial damage well and truly. In a word, this structural damage identification method based on multi-mode information fusion has better effects of structural damage identification and good practicability to actual structures.

Resource Allocation based on Hybrid Sharing Mode for Heterogeneous Services of Cognitive Radio OFDM Systems

  • Lei, Qun;Chen, Yueyun
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • 제9권1호
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    • pp.149-168
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    • 2015
  • In cognitive radio networks (CRNs), hybrid overlay and underlay sharing transmission mode is an effective technique for improving the efficiency of radio spectrum. Unlike existing works in the literature, where only one secondary user (SU) uses overlay and underlay modes, the different transmission modes should be allocated to different SUs, according to their different quality of services (QoS), to achieve the maximal efficiency of radio spectrum. However, hybrid sharing mode allocation for heterogeneous services is still a challenge in CRNs. In this paper, we propose a new resource allocation method for hybrid sharing transmission mode of overlay and underlay (HySOU), to achieve more potential resources for SUs to access the spectrum without interfering with the primary users. We formulate the HySOU resource allocation as a mixed-integer programming problem to optimize the total system throughput, satisfying heterogeneous QoS. To decrease the algorithm complexity, we divide the problem into two sub-problems: subchannel allocation and power allocation. Cutset is used to achieve the optimal subchannel allocation, and the optimal power allocation is obtained by Lagrangian dual function decomposition and subgradient algorithm. Simulation results show that the proposed algorithm further improves spectrum utilization with a simultaneous fairness guarantee, and the achieved HySOU diversity gain is a satisfactory improvement.

Method of Integrating Landsat-5 and Landsat-7 Data to Retrieve Sea Surface Temperature in Coastal Waters on the Basis of Local Empirical Algorithm

  • Xing, Qianguo;Chen, Chu-Qun;Shi, Ping
    • Ocean Science Journal
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    • 제41권2호
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    • pp.97-104
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    • 2006
  • A useful radiance-converting method was developed to convert the Landsat-7 ETM+thermal-infrared (TIR) band's radiance ($L_{{\lambda},L7/ETM+}$) to that of Landsat-5 TM TIR ($L_{{\lambda},L5/TM+})$ as: $L_{{\lambda},L5/TM}=0.9699{\times}L_{{\lambda},L7/ETM+}+0.1074\;(R^2=1)$. In addition, based on the radiance-converting equation and the linear relation between digital number (DN) and at-satellite radiance, a DN-converting equation can be established to convert DN value of the TIR band between Landsat-5 and Landsat-7. Via this method, it is easy to integrate Landsat-5 and Landsat-7 TIR data to retrieve the sea surface temperature (SST) in coastal waters on the basis of local empirical algorithms in which the radiance or DN of Lansat-5 and 7 TIR band is usually the only input independent variable. The method was employed in a local empirical algorithm in Daya Bay, China, to detect the thermal pollution of cooling water discharge from the Daya Bay nuclear power station (DNPS). This work demonstrates that radiance conversion is an effective approach to integration of Landsat-5 and Landsat-7 data in the process of a SST retrieval which is based on local empirical algorithms.

Rapid Detection of Ovarian Cancer from Immunized Serum Using a Quartz Crystal Microbalance Immunosensor

  • Chen, Yan;Huang, Xian-He;Shi, Hua-Shan;Mu, Bo;Lv, Qun
    • Asian Pacific Journal of Cancer Prevention
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    • 제13권7호
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    • pp.3423-3426
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    • 2012
  • Background: The objective of this study was to measure the antibody content of NuTu-19 ovarian cancer cells in serum samples using a quartz crystal microbalance (QCM) immunosensor. Materials and Methods: NuTu-19 cells were first cultured onto the electrode surfaces of crystals in Dulbecco's modified Eagle medium, and then specified amounts of immunized serum samples of immunized rabbit were also added. The change in mass caused by specific adsorbtion of antibodies of NuTu-19 to the surfaces of the crystals was detected. Results: The change in resonance frequency of crystals caused by immobilization of NuTu-19 cells was from 83 to 429Hz. The antibody content of NuTu-19 detected was 341ng/ul. The frequency shifts were linearly dependent on the amount of antibody mass in the range of 69 to 340ng. The positive detection rate and the negative detection rate were 80% and 100%, respectively. Conclusion: This immunoassay provides a viable alternative to other early ovarian cancer detection methods and is particularly suited for health screening of the general population.

miRNA-1297 Induces Cell Proliferation by Targeting Phosphatase and Tensin Homolog in Testicular Germ Cell Tumor Cells

  • Yang, Nian-Qin;Zhang, Jian;Tang, Qun-Ye;Guo, Jian-Ming;Wang, Guo-Min
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권15호
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    • pp.6243-6246
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    • 2014
  • To investigate the role of miR-1297 and the tumor suppressor gene PTEN in cell proliferation of testicular germ cell tumors (TGCT). MTT assays were used to test the effect of miR-1297 on proliferation of the NCCIT testicular germ cell tumor cell line. In NCCIT cells, the expression of PTEN was assessed by Western blotting further. In order to confirm target association between miR-1297 and 3'-UTR of PTEN, a luciferase reporter activity assay was employed. Moreover, roles of PTEN in proliferation of NCCIT cells were evaluated by transfection of PTEN siRNA. Proliferation of NCCIT cells was promoted by miR-1297 in a concentration-dependent manner. In addition, miR-1297 could bind to the 3'-UTR of PTEN based on luciferase reporter activity assay, and reduced expression of PTEN at protein level was found. Proliferation of NCCIT cells was significantly enhanced after knockdown of PTEN by siRNA. miR-1297 as a potential oncogene could induce cell proliferation by targeting PTEN in NCCIT cells.

Elevated Serum Ferritin Levels in Patients with Hematologic Malignancies

  • Zhang, Xue-Zhong;Su, Ai-Ling;Hu, Ming-Qiu;Zhang, Xiu-Qun;Xu, Yan-Li
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권15호
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    • pp.6099-6101
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    • 2014
  • Purpose: To retrospectively analyze variability and clinical significance of serum ferritin levels in Chinese patients with hematologic malignancies. Materials and Methods: Serum ferritin were measured by radioimmunoassay, using a kit produced by the Beijing Institute of Atomic Energy. Patients with hematologic malignancies, and treated in the Department of Hematology in Nanjing First Hospital and fulfilled study criteria were recruited. Results: Of 473 patients with hematologic malignancies, 262 patients were diagnosed with acute leukemia, 131 with lymphoma and 80 with multiple myeloma. Serum ferritin levels of newly diagnosed and recurrent patients were significantly higher than those entering complete remission stage or in the control group (p<0.001). Conclusions: Serum ferritin lever in patients with hematologic malignancies at early stage and recurrent stage are significantly increased, so that detection and surveillance of changes of serum ferritin could be helpful in assessing conditions and prognosis of this patient cohort.

VEGFR2 Expression in Head and Neck Squamous Cell Carcinoma Cancer Cells Mediates Proliferation and Invasion

  • Xu, Hui-Min;Zhu, Jian-Guo;Gu, Lian;Hu, Song-Qun;Wu, Hao
    • Asian Pacific Journal of Cancer Prevention
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    • 제17권4호
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    • pp.2217-2221
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    • 2016
  • Vascular endothelial growth factor 2 (VEGFR2) was initially identified as a receptor of VEGF on endothelial cells with a role in regulating angiogenesis during organism development and tumorigenesis. Previously, in cancer tissue, VEGFR2 has been reported to be expressed in endothelial cells. In our research, we found that VEGFR2 was expressed not only in endothelial cells but also cancer cells in head and neck squamous cell carcinomas (HNSCCs). Knockdown of VEGFR2 in Hep2 cells could arrest the cell cycle in G0/G1, leading to a decrease in proliferation. We also present evidence that MAPK/ERK signal pathways and expression of CDK1 downstream of VEGFR2 might regulate proliferation and cell cycle arrest. Furthermore, we discovered that down-regulate VEGRF2 in Hep2 cells could significantly affect the invasion ability. Taken together, our data suggest that VEGFR2 might regulate proliferation and invasion in HNSCC cancer cells in vivo.

당대와 송대의 여자면식에 관한 연구 (A Study on Woman's Make-up and Adorment of Dang and Song Dynasty)

  • 이순자
    • 한국농촌생활과학회지
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    • 제8권2호
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    • pp.93-110
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    • 1997
  • The customs of women s riding horse was prevalent in thriving period. The face toilet was mainly used by Gau Chang pattern. Wha Jun (chinen; Hwa-Qun(화전), make-up on forehead), was influenced nearly by Gua Chang and distantly by India. Penciling eyebrows with blue was transmitted from persia. Chinese cosmetics was most influenced during Tang Dynasty for it's colorful make-up and facial decorations such as Aek-Whang(액황), Wha-Jung(화전), Jang-Yob(장엽), Swa-Hong(사홍) and those made many Dynasty, since those kinds of styles were the result of mixture between traditional chinese and western styles, it became so unique and diverse. The Declining period of the Tang Dynasty has begun from the turning point, resulting from Rebellion of An Ru Sha'. Rebellion of An Ru Sha' made the chinese people have a sense of precaution, and an antipathy against babarian. Furthermore, the power of Tang Dynasty onto the countries bordering on western china unfortunately was declining due to the defeat at 99 the Talas war in 751. As the fashion of ‘Ho’ disappeared the costume pattern was restored to the traditional Chinese style of large sleeve and broad width. However, the Tibetan mode was appeared in women's hair style and face toilet since Yuan Ha (801-812). In Song Dynasty, women's make-up and adorment were originated from Dang Dynasty, but those were more simple than in Dang Dynasty.

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Protein Cyclization Enhanced Thermostability and Exopeptidase-Resistance of Green Fluorescent Protein

  • Zhao, Zhonglin;Ma, Xin;Li, Liang;Zhang, Wei;Ping, Shuzhen;Xu, Ming-Qun;Lin, Min
    • Journal of Microbiology and Biotechnology
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    • 제20권3호
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    • pp.460-466
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    • 2010
  • A mutant of green fluorescent protein ($GFPmut3^*$) from the jellyfish Aequorea victoria was cyclized in vitro and in vivo by the use of a naturally split intein from the dnaE gene of Synechocystis species PCC6803 (Ssp). Cyclization of $GFPmut3^*$ was confirmed by amino acid sequencing and resulted in an increased electrophoretic mobility compared with the linear $GFPmut3^*$. The circular $GFPmut3^*$ was $5^{\circ}C$ more thermostable than the linear form and significantly more resistant to proteolysis of exopeptidase. The circular $GFPmut3^*$ also displayed increased relative fluorescence intensity. In addition, chemical stability of $GFPmut3^*$ against GdnHCl revealed more stability of the circular form compared with the linear form.

Overexpression of Long Non-Coding RNA HOTAIR Promotes Tumor Growth and Metastasis in Human Osteosarcoma

  • Wang, Bo;Su, Yun;Yang, Qun;Lv, Decheng;Zhang, Weiguo;Tang, Kai;Wang, Hong;Zhang, Rui;Liu, Yang
    • Molecules and Cells
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    • 제38권5호
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    • pp.432-440
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    • 2015
  • Human osteosarcoma usually presented a high tendency to metastatic spread and caused poor outcomes, however, the underlying mechanism was still largely unknown. In the present study, using a series of in vitro experiments and an animal model, we investigated the roles of HOX antisense intergenic RNA (HOTAIR) during the proliferation and invasion of osteosarcoma. According with our results, HOTAIR was commonly overexpressed in osteosarcoma, which significantly correlated with advanced tumor stage, highly histological grade and poor prognosis. In vitro and in vivo experiments demonstrated that knockdown of HOTAIR could notably suppress cellular proliferation, inhibit invasion and decrease the secretion of MMP2 and MMP9 in osteosarcoma. Collectively, our results suggested that HOTAIR might be a potent therapeutic target for osteosarcoma.