• 제목/요약/키워드: Quantitative research

검색결과 7,180건 처리시간 0.043초

Evaluation of the Remineralization Capacity of Water-based Silver Fluoride

  • Gwangsuk Kim;Juhyun Lee;Haeni Kim
    • 대한소아치과학회지
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    • 제51권1호
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    • pp.80-87
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    • 2024
  • Silver diamine fluoride, which can arrest dental caries, is alkaline and may cause mild soft tissue irritation. Water-based silver fluoride has a neutral pH, which is closer to the physiological range, and is biocompatible for use in the oral environment. This study aimed to evaluate the effect of water-based silver fluoride on remineralizing early enamel lesions by comparing it with other fluoride agents through microhardness and quantitative light-induced fluorescence measurements. An in vitro study with intact bovine incisors was performed. Artificial enamel lesions were induced and subjected to microhardness and quantitative light-induced fluorescence testing. Specimens were randomly divided into 4 groups for treatment. The specimens in group I were treated with water-based silver fluoride and potassium iodide, group II with silver diamine fluoride and potassium iodide, group III with sodium fluoride varnish, and group IV with distilled water. After 8 days of pH cycling, the specimens were subjected to microhardness and quantitative light-induced fluorescence testing. Water-based silver fluoride and silver diamine fluoride showed the greatest increases in microhardness and quantitative light-induced fluorescence, with no significant differences between the two. Sodium fluoride varnish also exhibited a significant increase in microhardness and quantitative light-induced fluorescence, but the differences were smaller than those for water-based silver fluoride and silver diamine fluoride. Water-based silver fluoride is considered useful in a clinical setting for remineralizing enamel lesions, with the advantages of no risk of tissue burn and improved taste and smell.

연계선/그리드 사고시 풍력발전단지의 맥놀이 현상에 대한 정량적 분석 (Quantitative Analysis on Beat Phenomenon of a Wind Farm for Intertie/Grid Faults)

  • 김환철;이혜원;이상철;정태영;강용철
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 2011년도 제42회 하계학술대회
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    • pp.91-92
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    • 2011
  • Beat is a phenomenon, where the magnitudes and frequencies of the voltage and the current fluctuate. This paper describes a quantitative analysis of the beat phenomenon of a wind farm using the envelope of a current during intertie/grid fault conditions. In this paper, the ratio of the crest to the trough of the envelope curve and the time interval between adjacent troughs are defined and used to evaluate the beat phenomenon quantitatively. Beat phenomena under various fault and wind conditions are analyzed. The proposed quantitative analysis seems simple but effective in the more understanding of beat phenomenon of a wind farm, and thus can be used as a basis for operation and/or protection of an intertie.

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공동주택 단위주호의 공간구성유형에 따른 정량적 평가지표에 관한 연구 (A Study of Quantitative Evaluation Indicators on Residential Units in Multiple Stock Housing based on Space Composition Types)

  • 이병호;이건원;여영호
    • KIEAE Journal
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    • 제10권5호
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    • pp.43-55
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    • 2010
  • This research investigated 162 residential unit plans which were located in Seoul and Gyonggi Province ranging from 58 to $118m^2$ unit net area recently. Through the investigation of unit plans, a matrix was developed based on the 5 criteria for space composition types. 5 criteria are building stock types, W/D ratio of units, unit net area, number of bay to the main orientation, and openness types. After review the matrix, 10 typical unit types were selected. At the same time, quantitative evaluation indicators were developed based on the 4 criteria such as efficiency, openness, flexibility, environmental sustainability. On each criterion, 3 indicators were developed, and measured on 162 residential unit plans. Firstly, correlation analysis were pursued on 5 criteria for space composition types and 12 quantitative evaluation indicators, and reviewed on each other. Finally, quantitative evaluation indicators of 10 typical unit types were displayed on radar charts in order to show the integrated evaluation on 4 criteria such as efficiency, openness, flexibility, environmental sustainability. From the reviews and radar chart analyses, advantages, disadvantages, and improvements on each typical unit type were presented as research results.

만성 조현병 환자의 시계 그리기 검사 수행과 신경심리 기능 간의 관련성 (Relationship between Clock-Drawing Performance and Neuropsychological Functions in Patients with Chronic Schizophrenia)

  • 권미연;박민석;김명선
    • 대한조현병학회지
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    • 제23권1호
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    • pp.15-28
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    • 2020
  • Objectives: This study investigated the relationship between clock-drawing test (CDT) performance and neuropsychological functions in patients with chronic schizophrenia. Methods: Thirty-one patients with schizophrenia and 30 healthy controls participated in this study. The CDT was administered in three conditions and analyzed using both quantitative and qualitative scoring systems. Comprehensive neuropsychological tests were administered. Results: The results of the quantitative analysis showed that the schizophrenia group performed significantly worse in all three conditions of the CDT compared with the control group. However, no significant differences were observed between the two groups, when the IQ and educational level were controlled. The qualitative analysis showed that the schizophrenia group exhibited significantly more errors in "graphic difficulty" compared with the control group. In addition, CDT quantitative scores were significantly correlated with visuospatial function, memory, attention and executive functions in patients with schizophrenia. Conversely, each qualitative error type was correlated with specific cognitive domains. Furthermore, "graphic difficulty" and "spatial/planning deficit" were identified as predictors of depression symptoms in patients with schizophrenia. Conclusion: The present study demonstrated that the CDT is useful for assessing cognitive dysfunctions in patients with schizophrenia, while qualitative analyses provide more specific information about cognitive deficits compared with quantitative analyses.

Towards Quantitative Assessment of Human Exposures to Indoor Radon Pollution from Groundwater

  • Donghan Yu;Lee, Han-Soo
    • Journal of Korean Society for Atmospheric Environment
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    • 제17권E2호
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    • pp.43-51
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    • 2001
  • A report by the national research council in the United States suggested that many lung cancer deaths each year be associated with breathing radon in indoor air. Most of the indoor radon comes directly from soil beneath the basement of foundations. Recently, radon released from groundwater is found to contribute to the total inhalation risk from indoor air. This study presents the quantitative assessment of human exposures to radon released from the groundwater into indoor air. At first, a three-compartment model is developed to describe the transfer and distribution of radon released from groundwater in a house through showering, washing clothes, and flushing toilets. Then, to estimate a daily human exposure through inhalation of such radon for an adult. a physiologically-based pharmacokinetic(PBPK) model is developed. The use of a PBPK model for the inhaled radon could provide useful information regarding the distribution of radon among the organs of the human body. Indoor exposure patterns as input to the PBPK model are a more realistic situation associated with indoor radon pollution generated from a three-compartment model describing volatilization of radon from domestic water into household air. Combining the two models for inhaled radon in indoor air can be used to estimate a quantitative human exposure through the inhalation of indoor radon for adults based on two sets of exposure scenarios. The results obtained from the present study would help increase the quantitative understanding of risk assessment issues associated with the indoor radon released from groundwater.

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Prediction on the Chiral Behaviors of Drugs with Amine Moiety on the Chiral Cellobiohydrolase Stationary Phase Using a Partial Least Square Method

  • Choi, Sun-Ok;Lee, Seok-Ho;Park Choo , Hea-Young
    • Archives of Pharmacal Research
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    • 제27권10호
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    • pp.1009-1015
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    • 2004
  • Quantitative Structure-Resolution Relationship (QSRR) using the Comparative Molecular Field Analysis (CoMFA) software was applied to predict the chromatographic behaviors of chiral drugs with an amine moiety on the chiral cellobiohydrolase (CBH) columns. As a result of the Quantitative CoMFA-Resolution Relationship study, using the partial least square method, prediction of the behavior of drugs with amine moiety upon chiral separation became possible from their three dimensional molecular structures. When a mixed mobile phase of 10 mM aqueous phosphate buffer (pH 7.0) - isopropanol (95 : 5) was employed, the best Quantitative CoMFA-Resolution Relationship, derived from the study, provided a cross-validated $q^2$ = 0.933, a normal $r^2$ = 0.995, while the best Quantitative CoMFA-Separation Factor Relationship, also derived from the study, yielded a cross-validated $q^2$ = 0.939, a normal $r^2$ = 0.991. When all of these results are considered, this QSRR-CoMFA analysis appears to be a very useful tool for the preliminary prediction on the chromatographic behaviors of drugs with an amine moiety inside chiral CBH columns.

에틸렌 생산에서의 CO2 국가배출계수 검증 및 정량평가 방법론 (Methodology of CO2 Emission Factor Verification and Quantitative Assessment in Ethylene Product Processes)

  • 육수경;전의찬;유경선
    • 한국기후변화학회지
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    • 제9권1호
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    • pp.69-74
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    • 2018
  • The purpose of this study is to suggest the methodology of $CO_2$ Emission Factor Verification and Quantitative Assessment in Ethylene Product Processes. At first, this study compare the IPCC (Intergovernmental Panel on Climate Change) 1996 Guideline and 2006 Guideline. And analyse methodology for estimating $CO_2$ emission and $CO_2$ emission factor in Ethylene product process. Also analyse cases of estimating $CO_2$ emission factor based on material balance. Methodology of $CO_2$ Emission Factor Verification and Quantitative Assessment are following the categories proposed by GIR (Greenhouse Gas Inventory and Research Center). There are total 12 factors in 8 categories and give 5 or 10 points according to their importance. Also this study suggests necessary data of document to meet the conditions. The result would help estimate accuracy Greenhouse Gas Inventory. Also contribute to establish policy on environmental assessment, air conservation, etc.

화력발전설비 위험도 평가를 통한 기기별 정비주기 예측 (Prediction of Maintenance Period of Equipment Through Risk Assessment of Thermal Power Plants)

  • 송기욱;김범신;최우성;박명수
    • 대한기계학회논문집A
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    • 제37권10호
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    • pp.1291-1296
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    • 2013
  • 위험도 평가 기술은 주로 플랜트의 많은 운영설비 중 대형사고나 피해를 유발할 수 있는 위험설비를 선별하는 목적으로 개발되었다. 설비의 위험도를 평가하여 위험도의 크기에 따라 순위를 정하고 이 순위를 기준으로 정비자원을 투입하는 순서나 정비작업의 시급성을 판단한다. 위험도란 고장이 발생할 확률과 고장이 발생할 경우에 수반되는 파손피해의 곱으로 정의된다. 위험도 평가방법으로는 간단한 손상 및 고장 평가기법을 이용하여 기본적인 고장확률 데이터를 확보하고 정성적인 문진을 통해 이를 보완하는 준 정량적 방법이 많이 사용되고 있다. 본 논문에서는 준 정략적 평가를 이용하여 석탄화력발전소의 보일러설비에 대한 위험도 평가를 수행하고 이를 기반으로 설비 별차기 정비주기를 선정하였다.

A Simple Carbamidomethylation-Based Isotope Labeling Method for Quantitative Shotgun Proteomics

  • Oh, Donggeun;Lee, Sun Young;Kwon, Meehyang;Kim, Sook-Kyung;Moon, Myeong Hee;Kang, Dukjin
    • Mass Spectrometry Letters
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    • 제5권3호
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    • pp.63-69
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    • 2014
  • In this study, we present a new isotope-coded carbamidomethylation (iCCM)-based quantitative proteomics, as a complementary strategy for conventional isotope labeling strategies, with providing the simplicity, ease of use, and robustness. In iCCM-based quantification, two proteome samples can be separately isotope-labeled by means of covalently reaction of all cysteinyl residues in proteins with iodoacetamide (IAA) and its isotope (IAA-$^{13}C_2$, $D_2$), denoted as CM and iCCM, respectively, leading to a mass shift of all cysteinyl residues to be + 4 Da. To evaluate iCCM-based isotope labeling in proteomic quantification, 6 protein standards (i.e., bovine serum albumin, serotransferrin, lysozyme, beta-lactoglobulin, beta-galactosidase, and alpha-lactalbumin) isotopically labeled with IAA and its isotope, mixed equally, and followed by proteolytic digestion. The resulting CM-/iCCM-labeled peptide mixtures were analyzed using a nLC-ESI-FT orbitrap-MS/MS. From our experimental results, we found that the efficiency of iCCM-based quantification is more superior to that of mTRAQ, as a conventional nonisobaric labeling method, in which both of a number of identified peptides from 6 protein standards and the less quantitative variations in the relative abundance ratios of heavy-/light-labeled corresponding peptide pairs. Finally, we applied the developed iCCM-based quantitative method to lung cancer serum proteome in order to evaluate the potential in biomarker discovery study.

의복원형 설계의 착의 평가방법 비교 - 학령기 비만 남아를 중심으로 - (A Comparison of Wearing Evaluation Method for Bodice Pattern - Focusing on Obese Boys of School Year -)

  • 조윤주;이정란
    • 한국의류산업학회지
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    • 제4권4호
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    • pp.383-393
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    • 2002
  • The purpose of this study was to evaluate wearing evaluation method in order to propose well fitted bodice pattern. For this study, the subjects were drawn from obese boys at the ages 9 to 11. Wearing evaluation had use of 3 bodice type and 3 evaluative method. The appearance evaluation was to evaluate subjects by professional group. The functional evaluation was to valued subjects by self-evaluation. The quantitative evaluation was to estimate subjects through Electomyograph. Wearing evaluation was done through questionnaire of 32 item in objectivity, 36 item in subjectivity, and 36 item in quantity. The data were analyzed by using ANOVA. From wearing evaluation, appearance and functional evaluation had significant most of them but quantitative evaluation had not significant. It was known that the human sense was more sensitive the quantitative mechanism. And its obtained by both functional evaluation and quantitative evaluation, respectively was found to be significantly correlated, Independent relation was observed in the results from both appearance evaluation and functional evaluation as well as from both functional evaluation and quantitative evaluation. Therefore, we propose that it is proper to evaluate the propriety of bodice pattern for obese boys of school year, mutually compromising both appearance evaluation and functional evaluation or both functional evaluation and quantitative evaluation.