• 제목/요약/키워드: Quantitative parameters

검색결과 1,130건 처리시간 0.024초

Quantitative Ultrasound Radiofrequency Data Analysis for the Assessment of Hepatic Steatosis in Nonalcoholic Fatty Liver Disease Using Magnetic Resonance Imaging Proton Density Fat Fraction as the Reference Standard

  • Sun Kyung Jeon;Jeong Min Lee;Ijin Joo;Sae-Jin Park
    • Korean Journal of Radiology
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    • 제22권7호
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    • pp.1077-1086
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    • 2021
  • Objective: To investigate the diagnostic performance of quantitative ultrasound (US) parameters for the assessment of hepatic steatosis in patients with nonalcoholic fatty liver disease (NAFLD) using magnetic resonance imaging proton density fat fraction (MRI-PDFF) as the reference standard. Materials and Methods: In this single-center prospective study, 120 patients with clinically suspected NAFLD were enrolled between March 2019 and January 2020. The participants underwent US examination for radiofrequency (RF) data acquisition and chemical shift-encoded liver MRI for PDFF measurement. Using the RF data analysis, the attenuation coefficient (AC) based on tissue attenuation imaging (TAI) (AC-TAI) and scatter-distribution coefficient (SC) based on tissue scatter-distribution imaging (TSI) (SC-TSI) were measured. The correlations between the quantitative US parameters (AC and SC) and MRI-PDFF were evaluated using Pearson correlation coefficients. The diagnostic performance of AC-TAI and SC-TSI for detecting hepatic fat contents of ≥ 5% (MRI-PDFF ≥ 5%) and ≥ 10% (MRI-PDFF ≥ 10%) were assessed using receiver operating characteristic (ROC) analysis. The significant clinical or imaging factors associated with AC and SC were analyzed using linear regression analysis. Results: The participants were classified based on MRI-PDFF: < 5% (n = 38), 5-10% (n = 23), and ≥ 10% (n = 59). AC-TAI and SC-TSI were significantly correlated with MRI-PDFF (r = 0.659 and 0.727, p < 0.001 for both). For detecting hepatic fat contents of ≥ 5% and ≥ 10%, the areas under the ROC curves of AC-TAI were 0.861 (95% confidence interval [CI]: 0.786-0.918) and 0.835 (95% CI: 0.757-0.897), and those of SC-TSI were 0.964 (95% CI: 0.913-0.989) and 0.935 (95% CI: 0.875-0.972), respectively. Multivariable linear regression analysis showed that MRI-PDFF was an independent determinant of AC-TAI and SC-TSI. Conclusion: AC-TAI and SC-TSI derived from quantitative US RF data analysis yielded a good correlation with MRI-PDFF and provided good performance for detecting hepatic steatosis and assessing its severity in NAFLD.

다이아몬드 터닝 가공에서의 비철금속에 대한 미세절삭력 특성 연구 (A Study on Cutting Force Characteristics of Non-ferrous steel in Diamond Turning Process)

  • 정상화;김상석;차경래;김현욱;나윤철;홍권희;김건희;김효식
    • 한국공작기계학회:학술대회논문집
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    • 한국공작기계학회 2001년도 추계학술대회(한국공작기계학회)
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    • pp.38-42
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    • 2001
  • A complete quantitative understanding of DT has been difficult because the process represents such a broad field of research. The experimental measurement of tool force is a single area of DT which still covers a wide range of possibilities. There are numerous parameters of the process which affect cutting forces. There are also many turnable materials of current interest. To obtain information toward a better understanding of the process, a few cutting parameters and materials were selected for detail study. It was decided that free-oxygen copper and 6061-T6 alloy aluminum would be the primary test materials. There are materials which other workers have also used because of there wide use in reflective applications. The experimental phase of the research project began by designing tests to isolate certain cutting parameters. The parameters chosen to study were those that affected the cross-sectional area of the uncut chip. The specific parameters which cause this area to vary are the depth of cut and infeed per revolution, or feedrates. Other parameter such a tool nose radius and surface roughness were investigated as they became relevant to the research.

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해석적인 방법을 이용한 복잡한 형상의 자동차 부재 스탬핑 공정에서의 주요 설계인자 연구 (Study on Design Parameters in a Stamping Process of an Automotive Member with the Simulation-based Approach)

  • 송정한;김세호;김승호;허훈
    • 소성∙가공
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    • 제14권1호
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    • pp.21-28
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    • 2005
  • This paper is concerned with the quantitative effect of design parameters on a stamped part of the auto-body. The considered parameters in this paper are the blank holding force, the draw-bead force, the blank size which greatly affect the metal flow during stamping. The indicators of formability selected in this paper are failures such as tearing, wrinkling and the amount of springback. The stamping process of the front side inner member is simulated using the finite element analysis changing the design parameters. The numerical results demonstrate that the blank holding force cannot control the local metal flow during forming although it controls the overall metal flow. The modification of the initial blank size considering the punch opening line ensures the local wrinkling and reduces the amount of springback after forming. The restraining force of draw-bead controls the metal flow in the local area and reduces the amount of excess metal. It is noted that the parametric study of design parameters such as blank holding force, the blank size and the draw-bead are very important in the process design of the complicated member.

다이아몬드 터닝 가공공정에서의 미세절삭력 특성 연구 (A Study on Cutting Force Characteristics in Diamond Turning Process)

  • 정상화;김상석;차경래;김건희;김근홍
    • 한국정밀공학회:학술대회논문집
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    • 한국정밀공학회 1997년도 추계학술대회 논문집
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    • pp.957-960
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    • 1997
  • A complete quantitative understanding of DT has been difficult because the process represents such s broad field of research. The experimental measurement of tool force is a single area of DT which still covers a wide range of possibilities. Here are numerous parameters of the process which affect cutting forces. There are also many turnable materials of current interest. To obtain information toward a better understanding of the process, a few cutting parameters and materials were selected for detail study. It was decided that free-oxygen copper and 6061-T6 alloy aluminum would be the primary test materials. There are materials which other workers have also used because of there wide use in reflective applications. The experimental phase of the research project began by designing tests to isolate certain cutting parameters. The parameters chosen to study were those that affected the cross-sectional area of the uncut chip. The specific parameters which cause this area to vary are the depth of cut and infeed per revolution, or feedrates. Other parameter such a tool nose radius and surface roughness were investigated as they became relevant to the research.

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Quantitative Analysis of the Swimming Movements of Flatfish Reacting to the Ground Gear of Bottom Trawls

  • Kim, Yong-Hae;Wardle Clem S.
    • Fisheries and Aquatic Sciences
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    • 제9권4호
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    • pp.167-174
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    • 2006
  • Two typical responses have been documented for flatfish when they encounter the ground gear of bottom trawls: herding response and falling back response. These two responses were analyzed from video recordings of fish and were characterized by time sequences for four parameters: swimming speed, angular velocity, acceleration, and distance between the fish and the ground gear. When flatfish displayed the falling-back response, absolute values of the three swimming parameters and their deviations were significantly higher than those during the herding response. However, the swimming parameters were not dependent on the distance between the flatfish and the ground gear, regardless of which response occurred. The dominant periods for most of the movement parameters ranged from 2.0 to 3.7 s, except that no periodicity was observed for swimming speed or angular velocity during the falling-back response. However, variations in the four parameters during the falling -back response revealed greater irregularity in periodicity and higher amplitudes. This complex behavior is best described as a chaos phenomenon' and is discussed as the building block for a model predicting the responses of flatfish to ground gear as part of the general understanding of the fish capture process.

다꾸찌방법을 사용한 여러변수들이 패키지균열에 미치는 신뢰도 평가 (Estimate of package crack reliabilities on the various parameters using taguchi's method)

  • 권용수;박상선;박재완;채영석;최성렬
    • 대한기계학회논문집A
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    • 제21권6호
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    • pp.951-960
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    • 1997
  • Package crack caused by the soldering process in the surface mounting plastic package is evaluated by applying the maximum energy release rate criterion. It could be shown that the crack propagation from the lower edge of the ie pad is easily occurred at the maximum temperature during the soldering process, where the pressure acting on the crack surface is assumed by the saturated vapor pressure at maximum temperature. The package crack formation depends on various parameters such as chip size, relative thickness, material properties, the moisture content and soldering temperature etc. The quantitative measure of the effects of the parameters could be easily obtained by using the taguchi's method which requires only a few kinds of combinations with such parameters. From the results, it could be obtained that the more significant parameters to effect the package reliability are the orders of Young's modulus, die pad size, down set, chip thickness and maximum soldering temperature.

Data-Driven Modelling of Damage Prediction of Granite Using Acoustic Emission Parameters in Nuclear Waste Repository

  • Lee, Hang-Lo;Kim, Jin-Seop;Hong, Chang-Ho;Jeong, Ho-Young;Cho, Dong-Keun
    • 방사성폐기물학회지
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    • 제19권1호
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    • pp.75-85
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    • 2021
  • Evaluating the quantitative damage to rocks through acoustic emission (AE) has become a research focus. Most studies mainly used one or two AE parameters to evaluate the degree of damage, but several AE parameters have been rarely used. In this study, several data-driven models were employed to reflect the combined features of AE parameters. Through uniaxial compression tests, we obtained mechanical and AE-signal data for five granite specimens. The maximum amplitude, hits, counts, rise time, absolute energy, and initiation frequency expressed as the cumulative value were selected as input parameters. The result showed that gradient boosting (GB) was the best model among the support vector regression methods. When GB was applied to the testing data, the root-mean-square error and R between the predicted and actual values were 0.96 and 0.077, respectively. A parameter analysis was performed to capture the parameter significance. The result showed that cumulative absolute energy was the main parameter for damage prediction. Thus, AE has practical applicability in predicting rock damage without conducting mechanical tests. Based on the results, this study will be useful for monitoring the near-field rock mass of nuclear waste repository.

$k_0$-표준화방법에 의한 기기중성자방사화 분석법의 고찰 (The Review of Instrumental Neutron Activation Analysis by $k_0$-standardization method)

  • 문종화;정용삼;김선하
    • 분석과학
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    • 제14권4호
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    • pp.1075-1081
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    • 2001
  • 기기중성자방사화 분석법은 핵 분석기술의 대표적인 방법으로 비파괴-동시 다원소분석의 장점과 함께 절대측정값에 의해 정량 할 수 있다는 특징을 갖고 있다. 최근에는 정확도와 편의성을 만족할 수 있는 $k_0$-정량법을 사용한 기기중성자방사화 분석법이 세계적으로 일반화되고 있다. 본 연구에서는 $k_0$-법의 적용을 위하여 이 방법의 전체적인 개념의 소개와 함께 $k_0$-파라미터를 측정하고자 하였다. 이를 위하여 $k_0$-법의 개념이해와 정량에 필요한 인자들의 정의 및 파라미터인 $Q_0$(${\alpha}$)와 f 값을 결정하기 위한 수식과 실험적 측정방법 등을 요약하였고 중성자조사공에 따라 특성 값을 갖는 ${\alpha}$와 f 값을 하나로 연구용원자로의 방사화분석용 조사공(NAA#1)에서 측정하여 $k_0$-법의 도입을 위한 기반을 마련하였다.

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Quantitative study of acupuncture manipulation of lifting-thrusting using an needle insertion-measurement system in phantom tissue

  • Lee, Soo-Yoon;Son, Young-Nam;Choi, In-Hwa;Shin, Kyung-Min;Kim, Kap-Sung;Lee, Seung-Deok
    • 대한한의학회지
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    • 제35권4호
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    • pp.74-82
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    • 2014
  • Objectives: Quantification, objectification, and standardization of lifting-thrusting manipulation are important issues in traditional Chinese medicine (TCM). The purpose of this study was to quantitatively investigate the difference in the amount of stimulation according to range and frequency among parameters of lifting-thrusting manipulation with the use of a needle insertion-measurement system. Methods: For quantification of lifting-thrusting manipulation, an acupuncture needle insertion-measurement system was used in phantom tissue. The motor and force sensors of the needle insertion device were connected to the control software. This enabled operation of the lifting-thrusting manipulation and measurement of the acupuncture needle force. The measurement of the acupuncture needle force according to various frequencies (0.25, 0.50, 0.75, and 1 Hz) and ranges of movement (2, 4, 6, 8, and 10 mm) was repeated 10 times. Results: At a constant frequency of movement, acupuncture needle force according to range of movement (2, 4, 6, 8, and 10 mm) increased with increasing range of movement (p < 0.05). At a constant range of movement, acupuncture needle force according to frequency of movement (0.25, 0.50, 0.75, and 1.0 Hz) increased with increasing frequency of movement (p < 0.05). Conclusion: In this study, we conducted a quantitative comparison of the amount of stimulation according to range and frequency, the main parameters of lifting-thrusting manipulation, by using an acupuncture needle insertion-measurement system. Future studies on various manipulations and parameters are warranted to quantify and objectify the amounts of stimulation by acupuncture manipulation.

Renogram의 정량분석(定量分析)에 관(關)한 연구(硏究) (Quantitative Analysis of Renogram)

  • 최근출
    • 대한핵의학회지
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    • 제3권1호
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    • pp.19-32
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    • 1969
  • Radioisotope renography was carried out in 564 cases consisting of 150 normal controls, 140 hypertensives, 102 hypertensive nephropathys, 62 chronic renal diseases, non-functioning kidneys. It was aimed to study which parameter of the renogram is most applicable to any definite disease of the kidney. The analytical methods adopted were; Tobe, Spencer, Krueger, Matchida and Takeuchi. In the non-functioning kidney groups, the hemograms and serum nitrogen series were also studied to evaluate the relationships between the renograms and renal anemia. The parameters were; time of maximum amplitude (Tmax), half-time of maximum amplitude ($T\frac{1}{2}$), Kac value calculated from these two parameters in Tobe's method, slopes of Band C phase, B/A and B/C values in Spencer's method, total concentration (T.C.), minute concentration (M.C.) and minute excretion (M.E.) in Krueger's method, Matchida's K value and Takeuchi's renal function Index (R.F.I.). Following were the results: 1. In general, marked differences in the patterns of the renogram were observed between the normal controls and nephropathys. In Tobe's method, each parameter showed statistically significant delay or decrease in patients with hypertensive nephropathys and chronic renal diseases. In Spencer's method, slopes of B and C phase and B/C, also showed the statistically significant decrease in patients with hypertension, hypertensive nephropathys and chronic renal diseases. In Krueger's method, M.C. and ME showed the statistically significant differences between the control and patients with hypertension, hypertensive nephropathys and chronic renal diseases, In Matchida's method, K value showed the statistically significant differences between the control and patients with hypertensive nephropathys and chronic renal diseases. 2. It appeared, therefore, that Tobe's $T\frac{1}{2}$, Kac value, Spencer's slopes of Band C phase, B/A, B/C values, Krueger's T.C., M.C., and M.E. values, Matchida's K value are useful for the differentiation of various renal diseases, however, qualitative analysis of the renogram with one or two parameters is not accurate. 3. In bilateral non-functioning kidney groups, a positive correlation between anemia and nitrogen retention was observed, although the quantitative assessment of the degree of non-functioning was impossible.

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