• The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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• v.3 no.1
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• pp.1-8
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• 1998

The hydrographic data collected at three different times July, 1994, May, 1995 and June, 1996 around Taean peninsula in the mid-Yellow Sea off Korea, well known for the well-defined surface thermal fronts in summer, were analyzed. In the vertically well-mixed area where water depths varied from 15 m depth to 60 m depth, the temperature difference in the water column was less than $1^{\circ}C$. The temperature observed in the vertically well-mixed area was reversely related with the water depths and the coldest surface water was always observed over the deep channel with the depth of more than 50m, which developed southwestward off the promontory of Taean peninsula, irrespective of the observation period. The strengths of surface thermal front observed in June were much stronger than those in July, even though the surface temperature of stratified area were nearly the same as in July. These observed features could be explained as follows: A major physical process for the formation of the surface thermal front is the vertical mixing of water column but the detailed thermal structure in the study area depend on the physical parameters such as the water depth in the vertically well-mixed side and the vertical thermal structure in the stratified side.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.44 no.3
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• pp.231-238
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• 2018

The facial skin condition expresses physical healthy as well as is considered one of important factors for attractiveness. Especially, most people prefer shiny skin. So various cosmetics has been manufactured for expression of shiny skin. However, shiny skin is subjectively evaluated, and difficult to evaluate clear shininess using the existing method in oily skin. Moreover, there is no clear classification criteria between shininess and glossiness, which is assessed negatively in the skin. So there has not been a reference value by mechanical measurement to define and classify shiny skin from greasy skin. In this study, we measured skin biophysical parameters (gloss, hydration, translucency and sebum) and facial images which are selected by volunteers using sensory evaluation. According to the measurement results, the values of gloss, sebum, and translucency were similar in both shiny and greasy skin; the values of sebum and gloss increased, whereas those of translucency decreased. However only skin moisture values statistically increased in shiny skin. In conclusion, we propose objective assessment criteria for classifying shiny and greasy skin using device measurement and quantitative assessment.

• Korean Journal of Food Science and Technology
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• v.52 no.1
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• pp.26-30
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• 2020

This study was undertaken to determine the characteristics of xanthoangelol, the major chalcone constituent derived from the extracts of different parts of Lespedeza bicolor. Xanthoangelol was isolated from the root extract using column chromatography and used as a standard for quantitative analysis. The structure of the isolated compound was established based on spectroscopic evidence. The HPLC-DAD method was validated for specificity, linearity, precision, accuracy, limit of detection, and limit of quantitation. The calibration curve of xanthoangelol had significant linearity (R²>0.9999). Limit of detection and limit of quantitation 0.018 and 0.059 ㎍/mL, respectively. The relative standard deviation values of precision test, and intra- and inter-day tests were less than 0.22 and 0.40%, respectively. In the recovery test, the accuracy ranged from 98.98-102.78% with RSD values less than 0.13%. The method validation parameters indicate the applicability of the HPLC method for quality control of food or drug formulations containing L. bicolor.

• Korean Journal of Remote Sensing
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• v.36 no.5_2
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• pp.917-927
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• 2020

The Ministry of Land, Infrastructure and Transport of Korea is developing a CAS 500-1/2 satellite capable of photographing a GSD 0.5 m level image, and is developing a technology to utilize this. Therefore, this study attempted to develop a geospatial feature extraction technique aimed at automation as a technique for utilizing CAS 500-1/2 satellite images. KOMPSAT-3A satellite images that are expected to be most similar to CAS 500-1/2 were used for research and the possibility of automation of geospatial feature extraction was analyzed through relative radiometric normalization. For this purpose, the parameters and thresholds were applied equally to the reference images and relative radiometric normalized images, and the geospatial feature were extracted. The qualitative analysis was conducted on whether the extracted geospatial feature is extracted in a similar form from the reference image and relative radiometric normalized image. It was also intended to analyze the possibility of automation of geospatial feature extraction by quantitative analysis of whether the classification accuracy satisfies the target accuracy of 90% or more set in this study. As a result, it was confirmed that shape of geospatial feature extracted from reference image and relative radiometric normalized image were similar, and the classification accuracy analysis results showed that both satisfies the target accuracy of 90% or more. Therefore, it is believed that automation will be possible when extracting spatial objects through relative radiometric normalization.

• Journal of Korean Society of Forest Science
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• v.101 no.4
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• pp.640-647
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• 2012

A metabolomic study was conducted to identify key metabolic components, which are correlated with the growth of 4-year-old Pinus koraiensis seedlings harvested at actively height growing season (May 18th). Among 105 individual metabolites identified by GC/MS analysis, alanine, threonine, oleic acid, and butanoic acids were negatively correlated with both height and weight of 4-year-old seedlings, while malic acid, xylose, glucose, d-turanose and inositol had positive correlation with various growth parameters. During the actively growing season, the concentrations of both amino acids and organic acids in the main stem of Superior seedling group were lower but the photosynthates such as mono-saccharide and sucrose were higher than in other seedling groups such as Intermediate and Inferior. Interestingly, d-turanose, an analogue of sucrose that is not metabolized in higher plants but used as carbon source by many organisms including numerous species of bacteria and fungi, showed the highest correlation (r=0.896, p<0.001) with height of 4-year-old seedlings, indicating that possible interaction with mycorrhizal organisms. Therefore we suggest that several metabolites selected in this study may be used as metabolic markers for complex traits in P. koraiensis.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.11 no.6
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• pp.185-194
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• 2016

Recently, as the popularization of the mobile and the internet, the need of big data technology using a vast amount of data which contains the information has emerged. Big data technology has been used in various fields but use of the public sector is still insufficient. So, this study applies them. This study explores factors influencing silver industry as keywords, graving has effect on the present as well as future society. Results, five variables are 'silver Industry', 'senior citizen who lives alone', 'aging', 'birth' and 'retirement' were searched, and it was confirmed that they are correlated with one another. Results of analyzing the influence of the other four parameters on "Silver Industry", they have an effect significantly. In addition, it proposed the need of the 'providing living space of senior citizen who lives alone', 'childbirth support policy', 'support to vitalize silver startup senior manpower of technology' as an alternative to develop the silver industry. This study provided the theoretical implications that is exploring factors through a quantitative approach using big data and the practical implication is to suggest an alternative.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.2
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• pp.871-876
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• 2014

Objective: Desmogleins (DSGs) are major members among the desmosomal cadherins critically involved in cell-cell adhesion and the maintenance of normal tissue architecture in epithelia. Reports exploring links of DSG family member expression with cancers are few and vary. The aim of this study was to investigate the ratio of DSG2 and DSG3 mRNA expression in esophageal squamous cell carcinoma (ESCC) tissue to normal tissue (T/N ratio) and evaluate correlations with clinical parameters. Methods: The mRNA expression of DSGs, as well as ${\gamma}$-catenin and desmoplakin, was detected by real-time quantitative RT-PCR in 85 cases of ESCC tissue specimens. Results: The expression level of DSG3 mRNA was significantly higher than that of DSG2 in ESCC specimens (p=0.000). DSG3 mRNA expression highly correlated with histological grade (p=0.009), whereas that of DSG2 did not significantly relate to any clinicopathologic parameter. Kaplan-Meier survival analysis showed that only DSG3 expression had an impact on the survival curve, with negative DSG3 expression indicating worse survival (p=0.038). Multivariate Cox regression analysis demonstrated DSG3 to be an independent prognostic factor for survival. Furthermore, correlation analysis demonstrated the mRNA level of DSG3 to highly correlate with those of ${\gamma}$-catenin and desmoplakin in ESCC samples (p=0.000), implying that the expression of desmosomal components might be regulated by the same upstream regulatory molecules. Conclusions: Our findings suggest that DSG3 may be involved in the progression of ESCC and serve as a prognostic marker, while expression of DSG2 cannot be used as a predictor of ESCC patient outcome.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.7
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• pp.3431-3436
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• 2016

Background: Carcinogenesis is a multifaceted intricate cellular mechanism of transformation of the normal functions of a cell into neoplastic alterations. Metastasis may result in failure of conventional treatment and death Hence, research on metastatic suppressors in cancer is a high priority. The metastatic suppressor gene CD82, also known as KAI1, is a member of the transmembrane 4 superfamily which was first identified in carcinoma of prostate. Little work has been done on this gene in breast cancer. Herein, we aimed to determine the gene and protein level expression of CD82/KAI1 in breast cancer and its role as a prognosticator. Materials and Methods: In this study, 83 histologically proven cases of breast cancer and a similar number of controls were included. Patient age ranged from 18-70 years. Quantitative Real Time Polymerase Chain Reaction (q-RT PCR) and immunohistochemistry (IHC) were used to investigate KAI1 expression at gene and protein levels, respectively. Statistical analysis was done to correlate expression of KAI1 and clinicopathological parameters. Results: It was revealed that: (i) KAI1 was remarkably diminished in metastatic vs non metastatic breast cancer both at the gene and the protein levels (P < .05); (ii) KAI1 expression levels were strongly correlated with TNM staging, histological grade and advanced stage (p<0.001) and no association was found with any other studied parameter; (iii) Lastly, a significant correlation was observed between expression of KAI1 and overall median survival of BC patients (P = 0.04). Conclusions: Our results suggest that lack of expression of the KAI1 might indicate a more aggressive form of breast cancer. Loss of KAI1 may be considered a significant prognostic marker in predicting metastatic manifestation. When evaluated along with the clinical and pathological factors, KAI1 expression may be beneficial to tailor aggressive therapeutic strategies for such patients.

• Journal of Korean Neurosurgical Society
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• v.60 no.2
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• pp.225-231
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• 2017

Objective : Solid bone fusion is an essential process in spinal stabilization surgery. Recently, as several minimally invasive spinal surgeries have developed, a need of artificial bone substitutes such as demineralized bone matrix (DBM), has arisen. We investigated the in vivo bone growth rate of DBM as a bone void filler compared to a local autologous bone grafts. Methods : From April 2014 to August 2015, 20 patients with a one or two-level spinal stenosis were included. A posterior lumbar interbody fusion using two cages and pedicle screw fixation was performed for every patient, and each cage was packed with autologous local bone and DBM. Clinical outcomes were assessed using the Numeric Rating Scale (NRS) of leg pain and back pain and the Korean Oswestry Disability Index (K-ODI). Clinical outcome parameters and range of motion (ROM) of the operated level were collected preoperatively and at 3 months, 6 months, and 1 year postoperatively. Computed tomography was performed 1 year after fusion surgery and bone growth of the autologous bone grafts and DBM were analyzed by ImageJ software. Results : Eighteen patients completed 1 year of follow-up, including 10 men and 8 women, and the mean age was 56.4 (32-71). The operated level ranged from L3/4 to L5/S1. Eleven patients had single level and 7 patients had two-level repairs. The mean back pain NRS improved from 4.61 to 2.78 (p=0.003) and the leg pain NRS improved from 6.89 to 2.39 (p<0.001). The mean K-ODI score also improved from 27.33 to 13.83 (p<0.001). The ROM decreased below 2.0 degrees at the 3-month assessment, and remained less than 2 degrees through the 1 year postoperative assessment. Every local autologous bone graft and DBM packed cage showed bone bridge formation. On the quantitative analysis of bone growth, the autologous bone grafts showed significantly higher bone growth compared to DBM on both coronal and sagittal images (p<0.001 and p=0.028, respectively). Osteoporotic patients showed less bone growth on sagittal images. Conclusion : Though DBM alone can induce favorable bone bridging in lumbar interbody fusion, it is still inferior to autologous bone grafts. Therefore, DBM is recommended as a bone graft extender rather than bone void filler, particularly in patients with osteoporosis.

• Journal of Korean Society of Forest Science
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• v.87 no.3
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• pp.445-458
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• 1998

The present study focused on the vegetation structure and dynamics of Betula davurica forest were to provide the information for management, distribution and utilization of B. davurica forest in Mt. Chiri national park, southern Korea. The layer structure of B. davurica forest were consist of tree layer(18 species), middle layer(29 species), shrub layer(43 species) and herb layer(68 species). According to the importance value of stratification of layers, In tree layer, B. davurica dominant the highest value of 123.97%, Alnus hirsuta 49.04., Castanea crenata 25.58%, Quercus serrata 25.02%, Stewartia koreana 14.49%, in middle layer were B. davurica 70.81%, Q. serrata 37.74%, Fraxinus rhynchophylla 25.35% Lindera erythrocarpa 24.52%, S. koreana 18.86%, shrub layer were Sasa borealis 28.28%, L. erythrocarpa 24.94%, Rhus trichocarpa, 20.42%, Stephanandra incisa 19.90% and herb layer Schizandra chinensis 18.51%, Aster scaber 12.26%. Disporum smilacinum 10.63% etc, respectively. Results of chi-square test statistics based on presence-absence parameters, the positively associated species pair were Quercus variablis - Q. acutissima, Stewartia koreana - Symplocos paniculata, Acer pseudo-sieboldianum - Quercus mongolica. And covariation was calculated based on quantitative measure of density. The results showed that the association and covariation values among species not agreed with each other. The frequency distribution of DBH Betula davurica species showed reverse J-shaped, therefore it's seems to retrain as a dominant species. When predicting succession in Betula davurica forest, it is seedling and saplings were not richness, succession was governed by competition of hardwood species of subtree and tree layer.