• 대한의용생체공학회:의공학회지
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• 제22권1호
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• pp.49-58
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• 2001

본 연구에서는 진자 실험을 통하여 중추신경계 질환인 경직을 정량적으로 판정할 수 있는 새로운 LCL(Logically Classified Level) 척도(scale)가 개발되었다. 새로운 척도개발에는 총 30개의 변수가 사용되었다. 이를 위하여 실험결과의 통계적 분석이 수행되었고 이들 중 진자 실험에서 경직의 특성이 가장 잘 반영되는 변수가 대표변수로 선정되었다. 사용된 30개의 변수 중 20개는 새로 도출된 변수이며 10개는 선행된 연구자들에 의하여 개발된 변수이다. 새로운 20개의 변수들은 진자 실험에서 발생되는 특성들인 각도, 각속도, 근육 모델, EMG가 고르게 반영될 수 있도록 이들의 조합으로 도출되었다. 이변량 상관분석결과 총 30개의 변수들 중 11개의 변수들은 서로 밀접한 상관성이 있음이 파악되었다. 11개의 서로 강한 상관성을 보이는 변수 중 논리적인 모순이 없는 L11이 대표변수로 선택되었다. 28명의 환자 데이터는 대표변수인 L11를 기준으로 4개의 그룹으로 분리되었고 최종으로 이들 그룹의 경향을 예측할 수 있는 회귀 방정식을 유도하였다. 새로운 척도에 사용된 대표변수인 L11은 환자들에게서 나타날 수 있는 여러 경우에 적합한지 검토되었는데 미소한 환자의 상태까지 잘 반영하고 있음이 드러났다. 따라서 새로운 LCL 척도는 기존의 준 정량적인 척도인 MAS(Modified Ashworth Scale)를 대체할 수 있을 것으로 기대된다. 특히 환자의 초기 진단뿐만 아니라 동일한 환자의 치료전후, 병적 호전에 대하여 정밀하게 파악할 수 있어 약물의 처방량 조절, 치료기간 등 치료의 전략에 사용될 수 있을 것으로 기대된다.

• 화약ㆍ발파
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• 제25권1호
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• pp.67-77
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• 2007

본 연구에서는 NATM 터널 시공사이클에서 필수적으로 수행되는 천공작업 시 획득할 수 있는 정보를 통해 굴착 대상 암반의 특성을 평가하는 방안에 대해 고찰하였다. 활용 가능한 천공데이터는 천공속도, 피트압, 토크 등이 있으며, 이러한 인자들과 암반 특성들과의 상관관계를 규명하고자 하며 이러한 결과를 토대로 향후 정량적 발파설계를 위한 가이드라인을 제안하고자 하였다.

• Biomolecules & Therapeutics
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• 제8권1호
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• pp.63-72
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• 2000

We intended to show some basic requirements for spectrum analysis of electroencephalogram (EEG) by visualizing the differences of the results according to different values of some parameters for analysis. Spectrum analysis is the most popular technique applied for the quantitative analysis of the electroen- cephalographic signals. Each step from signal acquisition through spectrum analysis to presentation of parameters was examined with providing some different values of parameters. The steps are:(1) signal acquisition; (2) spectrum analysis; (3) parameter extractions; and (4) presentation of results. In the step of signal acquisition, filtering and amplification of signal should be considered and sampling rate for analog-to-digital conversion is two-time faster than highest frequency component of signal. For the spectrum analysis, the length of signal or epoch size transformed to a function on frequency domain by courier transform is important. Win dowing method applied for the pre-processing before the analysis should be considered for reducing leakage problem. In the step of parameter extraction, data reduction has to be considered so that statistical comparison can be used in appropriate number of parameters. Generally, the log of power of all bands is derived from the spectrum. For good visualization and quantitative evaluation of time course of the parameters are presented in chronospectrogram.

• 천문학회보
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• 제40권1호
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• pp.88.3-88.3
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• 2015

Kepler mission is performing the quantitative and qualitative observations. Hence, it is possible to statistically study, which is called 'Ensemble asteroseismology', about seismic properties. They investigated about global oscillation parameters. In this study, we performed statistically study about global seismic parameters with Kepler data. Relation between global oscillation parameters (${\Delta}{\nu}$ and ${\nu}max$) are approximately confirmed. We investigated newly about distribution of Full-With-at-Half-Maximum (FWHM) and relation between FWHM and other global oscillation parameters.

• 대한후두음성언어의학회지
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• 제13권1호
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• pp.5-17
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• 2002

Objectives : Videostrobokymography(VSK) has been recently developed and reported by Sung et at. We aimed to analyze vibratory patterns and objective parameters in various benign vocal fold lesions using VSK, and examine the efficacy of VSK in clinical application. Materials and Methods : Using VSK, we analyzed the vibration pattern of normal vocal fold and various benign lesions, such as nodules, polyps, cysts, Reinke's edema and unilateral vocal fold paralysis. We also calculated objective parameters, open quotient and asymmetric index, and compared them with mean values of parameters in normal controls. Results : In nodules, polyps, and cysts, the open quotient on the site of the lesion was similar to the mean value in normal controls, however, on the other part of the vocal folds it was much larger than normal mean value. In Reinke's edema, irregular and asymmetric vibration was observed. The posterior portion of the vocal folds showed larger open quotients than the anterior portion. In the unilateral vocal fold paralysis, irregular vocal folds vibration and incomplete closure of the vocal folds were documented. Much larger asymmetric indices were calculated in the unilateral vocal fold paralysis than in normal controls and other lesions. The asymmetric index could be a good quantitative parameter of vibration from a patient with vocal fold paralysis. Conclusion : This study demonstrated that VSK could generate clear quantitative documentations of fine vibrations of vocal folds in many different benign lesions. VSK has a potential as an effective tool for quantitative analysis of vibratory patterns of the vocal folds iii clinical settings.

• 한국자기공명학회논문지
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• 제24권1호
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• pp.30-37
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• 2020

Quantitative nuclear magnetic resonance (qNMR) has been gaining attention as a purity assessment method. In particular, qNMR is recognized as the primary method to realize the Internal System of Units (SI) in organic analysis. The capability of quantitative analysis is recognized as the beginning of NMR development. NMR signals are proportional to the number of nuclei and qNMR has been used in various fields, such as metabolomics and food and pharmaceutical analysis. However, careful sample preparation and thorough optimization of measurement parameters are required to obtain accurate and reliable results. In this review, quantitative methods used in qNMR are discussed, and the important factors to be considered also introduced. The recent development of qNMR techniques including combination with chromatography and, multidimensional NMR are also presented.

• 대한소아치과학회지
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• 제48권4호
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• pp.405-413
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• 2021

이 연구의 목적은 펜-타입 quantitative light-induced fluorescence(QLF) 장비의 임상적 유구치 인접면 우식 탐지 성능을 평가하는 것이다. 이를 위해 형광 소실, 적색 자기형광 그리고 인접면 우식을 위해 간편화된 QLF 평가 기준(QS-proximal)이 사용되었으며 교익 방사선 영상과 비교, 평가되었다. 총 344개의 유구치 인접면이 분석되었으며 인접면 우식 병소는 시진과 방사선학적 검사 그리고 QLF 검진을 통하여 평가되었다. QLF 영상들을 이용하여 분석된 QLF 매개변수들과 QS-proximal을 방사선학적 평가와 비교하여 장비의 법랑질과 상아질 우식 탐지 능력에 대한 민감도, 특이도 그리고 area under receiver operating curve(AUROC)가 계산되었다. 두 QLF 매개변수 모두 준수한 상아질 우식 탐지 능력을 보였으며 AUROC은 △F = 0.794, △R = 0.750였다. QS-proximal(0.757 - 0.769)은 시진(0.653)보다 더 높은 AUROC을 나타내었다. 결론적으로 펜-타입 QLF 장비는 방사선학적 평가와 비교하여 임상적으로 적용 가능한 성능을 보였다.

• 자원환경지질
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• 제33권1호
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• pp.77-88
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• 2000

The goal of this study is to assess the spatial distribution of natural slopes and cutting slopes under would-be development. For this goal, a quantitative slope stability analysis method using GIS integrated with a computer program was developed. Through field investigations, the discontinuity parameters were collected such as orientation of discontinuity, persistence, spacing, JRC, JCS, and water depth. The distributions were interpolated from the ordinary kriging method in ARC/INFO GIS after variogram analysis. The layers showing all parameters needed for limit equilibrium analysis were constructed. The final layer using GIS works composed of 162,352 polygons, that is, unit slopes. The rock slope stability analysis program was coded by C++ language. This program can calculate geometrical vectors related to rock block failures using input orientation data and direction and dimension of strength to occur failure. Also, this can calculate shear strength of joints through empirical equations and quantitative factors of safety. This methodology was applied to the study area which is located in Jaecheon city and Danyang-gun of the northeastern Keumsu is about 135$km^2$. As a result, the study area was entirely stable but unstable, that is, factor of safety less than 1.0dominantly at the slopes near Keumsil, Daejangri, Keumsungmyun and Sojugol, Mt. Dongsan, Juksongmyun by the natural slope stability analysis. Assuming the cutting slope showing the same direction immediate, and quantitative analysis of factors of safety for a regional area could be conducted through GIS integrated with a computer program of limit equilibrium.

• 대한기계학회논문집A
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• 제32권3호
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• pp.280-289
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• 2008

This paper presents design of the quantitative feedback control system of the three axes hydraulic road simulator with respect to the dummy wheel for uncertain multiple input-output(MIMO) feedback systems. This simulator has the uncertain parameters such as fluid compressibility, fluid leakage, electrical servo components and nonlinear mechanical connections. This works have reproduced the random input signal to implement the real road vibration's data in the lab. The replaced $m^2$ MISO equivalent control systems satisfied the design specifications of the original $m^*m$ MIMO control system and developed the mathematical method using quantitative feedback theory based on schauder's fixed point theorem. This control system illustrates a tracking performance of the closed-loop controller with low order transfer function G(s) and pre-filter F(s) having the minimum bandwidth for parameters of uncertain plant. The efficacy of the designed controller is verified through the dynamic simulation with combined hydraulic model and Adams simulator model. The Matlab simulation results to connect with Adams simulator model show that the proposed control technique works well under uncertain hydraulic plant system. The designed control system has satisfied robust performance with stability bounds, tracking bounds and disturbance. The Hydraulic road simulator consists of the specimen, hydraulic pump, servo valve, hydraulic actuator and its control equipments

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1997년도 추계학술대회
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• pp.39-43
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• 1997

Posturography stands or quantitative assessment of body postural stability analysis. The present study developed a balance plate system to monitor patient's center of pressure (COP) movement and to analyze its stability. An equilateral triangular shaped plate was made of duralumin and forces were measured on the three vertices of the plate using industrial load cells. Specially designed electronic circuit picked up force signals ed into data acquisition system to calculate the cartesian coordinates of COP. COP calculation error was less than 2%. The force signals enabled to compute stability measures, which consisted of a variety of clinical parameters related to postural stability. Clinical experiments were carefully designed and performed on 40 normal subjects. The results were that 1) postural stability decreased with age and 2) the best parameters were those of posture deviation measures. A customized PC-based software package was developed to apply the present technique with a great convenience to monitoring and analyzing postural stability in an accurate and quantitative way.