• Title/Summary/Keyword: Quantitative Research Method

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A Quantitative Assessment Model for Data Governance (Data Governance 정량평가 모델 개발방법의 제안)

  • Jang, Kyoung-Ae;Kim, Woo-Je
    • Journal of the Korean Operations Research and Management Science Society
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    • v.42 no.1
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    • pp.53-63
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    • 2017
  • Managing the quantitative measurement of the data control activities in enterprise wide is important to secure management of data governance. However, research on data governance is limited to concept definitions and components, and data governance research on evaluation models is lacking. In this study, we developed a model of quantitative assessment for data governance including the assessment area, evaluation index and evaluation matrix. We also, proposed a method of developing the model of quantitative assessment for data governance. For this purpose, we used previous studies and expert opinion analysis such as the Delphi technique, KJ method in this paper. This study contributes to literature by developing a quantitative evaluation model for data governance at the early stage of the study. This paper can be used for the base line data in objective evidence of performance in the companies and agencies of operating data governance.

Quantitative Analysis of Coumarins from Angelica gigas Using $^1H$-NMR

  • Yoo, Jong-Su;Ahn, Eun-Mi;Song, Myoung-Chong;Bang, Myun-Ho;Kim, Dong-Hyun;Han, Min-Woo;Kwak, Ho-Young;Lee, Dae-Young;Lyu, Ha-Na;Baek, Nam-In
    • Food Science and Biotechnology
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    • v.17 no.3
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    • pp.573-577
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    • 2008
  • $^1H$-Nuclear magnetic resonance (NMR) spectrometry was applied to the quantitative analysis of coumarins in the roots of Angelica gigas without any chromatographic purification. The experiment was performed by the analysis of each singlet germinal methyl, which was well separated in the range of 1.0-2.0 ppm in the $^1H$-NMR spectrum. The quantity of the compounds was calculated by the ratio of the intensity of each compound to the known amount of internal standard (dimethyl terephthalate). These results were compared with the conventional gas chromatography (GC) method. The contents of decursin and decursinol angelate in A. gigas were determined $1.98{\pm}0.07$, $1.13{\pm}0.08%$ in quantitative $^1H$-NMR method and $2.06{\pm}0.24$, $1.17{\pm}0.24%$ in GC method, respectively. The advantages of quantitative $^1H$-NMR analysis are that can be analyzed to identify and quantify, and no reference compounds required for calibration curves. Besides, it allows rapid and simple quantification for coumarins with an analysis time for only 10 min without any preprocessing.

Quantitative Analysis of PET Measurements in Tumors (종양학 분야에서 양전자방출촬영을 이용한 정량분석)

  • Choi, Chang-Woon
    • 대한핵의학회:학술대회논문집
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    • 2001.05a
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    • pp.60-65
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    • 2001
  • The positron emission tomography (PET) has been used for the evaluation of the characteristics of various tumors. The role of PET in oncology has been evolved from a pure research tool to a methodology of enormous clinical potential. The unique characteristics of PET imaging make sophisticated quantitation possible. Several quantitative methods, such as standardized uptake values (SUV), simplified quantitative method, Patlak graphical analysis, and Sokoloff's glucose metabolism measurement, have been used in the field of oncology. However, each quantitative method has limitations of its own. For example, the SUV has been used as a quantitative index of glucose metabolism for tumor classification and monitoring response to treatment, even though it depends on blood glucose level, body configuration of patient, and scanning time. The quantitative methods of PET are reviewed and strategy for implementing these methods are presented.

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A Comparison of Wearing Evaluation Method for Bodice Pattern - Focusing on Obese Boys of School Year - (의복원형 설계의 착의 평가방법 비교 - 학령기 비만 남아를 중심으로 -)

  • Jo, Youn-Joo;Lee, Jeong-Ran
    • Fashion & Textile Research Journal
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    • v.4 no.4
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    • pp.383-393
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    • 2002
  • The purpose of this study was to evaluate wearing evaluation method in order to propose well fitted bodice pattern. For this study, the subjects were drawn from obese boys at the ages 9 to 11. Wearing evaluation had use of 3 bodice type and 3 evaluative method. The appearance evaluation was to evaluate subjects by professional group. The functional evaluation was to valued subjects by self-evaluation. The quantitative evaluation was to estimate subjects through Electomyograph. Wearing evaluation was done through questionnaire of 32 item in objectivity, 36 item in subjectivity, and 36 item in quantity. The data were analyzed by using ANOVA. From wearing evaluation, appearance and functional evaluation had significant most of them but quantitative evaluation had not significant. It was known that the human sense was more sensitive the quantitative mechanism. And its obtained by both functional evaluation and quantitative evaluation, respectively was found to be significantly correlated, Independent relation was observed in the results from both appearance evaluation and functional evaluation as well as from both functional evaluation and quantitative evaluation. Therefore, we propose that it is proper to evaluate the propriety of bodice pattern for obese boys of school year, mutually compromising both appearance evaluation and functional evaluation or both functional evaluation and quantitative evaluation.

Relative Quantification of Glycans by Metabolic Isotope Labeling with Isotope Glucose in Aspergillus niger

  • Choi, Soo-Hyun;Cho, Ye-Eun;Kim, Do-Hyun;Kim, Jin-il;Yun, Jihee;Jo, Jae-Yoon;Lim, Jae-Min
    • Mass Spectrometry Letters
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    • v.13 no.4
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    • pp.139-145
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    • 2022
  • Protein glycosylation is a common post-translational modification by non-template-based biosynthesis. In fungal biotechnology, which has great applications in pharmaceuticals and industries, the importance of research on fungal glycoproteins and glycans is accelerating. In particular, the importance of quantitative analysis of fungal glycans is emerging in research on the production of filamentous fungal proteins by genetic modification. Reliable mass spectrometry-based techniques for quantitative glycomics have evolved into chemical, enzymatic, and metabolic stable isotope labeling methods. In this study, we intend to expand quantitative glycomics by metabolic isotope labeling of glycans in Aspergillus niger, a filamentous fungus model, by the MILPIG method. We demonstrate that incubation of filamentous fungi in a culture medium with carbon-13 labeled glucose (1-13C1) efficiently incorporates carbon-13 into N-linked glycans. In addition, for quantitative validation of this method, light and heavy glycans are mixed 1:1 to show the performance of quantitative analysis of various N-linked glycans simultaneously. We have successfully quantified fungal glycans by MILPIG and expect it to be widely applicable to glycan expression levels under various biological conditions in fungi.

Quantitative Determination of Styrene in Blood and Mandelic Acid in Urine of the Occupationally Styrene-exposed Workers

  • Yang, Jeong-Sun
    • Archives of Pharmacal Research
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    • v.17 no.2
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    • pp.76-79
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    • 1994
  • The concentration of styrne in blood of the occupationally syrene-exposed workers was checked by gas chromatographic headspace analysis. Mandelic acd in urine, that is a major metabolite of styrene, and hippuric acid wre also analyzed by high performance liquid chromatography. For the biological monitoring of styrene-exposed workers, the routine method of the quantitative determination of styrene nad its metabolites in the biolgical samples were studied.

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A Method for Quantitative Measurement of Lateral Flow Immunoassay Using Color Camera (컬러 카메라를 이용한 측면유동 면역 어세이 정량분석 방법)

  • Park, Jongwon
    • Journal of Biomedical Engineering Research
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    • v.35 no.1
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    • pp.1-7
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    • 2014
  • Among semi-quantitative or fully quantitative lateral flow assay readers, an image sensor-based instrument has been widely used because of its simple setup, cheap sensor price, and compact equipment size. For all previous approaches, monochrome CCD or CMOS cameras were used for lateral flow assay imaging in which the overall intensities of all colors were taken into consideration to estimate the analyte content, although the analyte related color information is only limited to a narrow wavelength range. In the present work, we introduced a color CCD camera as a sensor and a color decomposition method to improve the sensitivity of the quantitative biosensor system which utilizes the lateral flow assay successfully. The proposed setup and image processing method were applied to achieve the quantification of imitatively dispensed particles on the surface of a porous membrane first, and the measurement result was then compared with that using a monochrome CCD. The compensation method was proposed in different illumination conditions. Eventually, the color decomposition method was introduced to the commercially available lateral flow immunochromatographic assay for the diagnosis of myocardial infarction. The measurement sensitivity utilizing the color image sensor is significantly improved since the slopes of the linear curve fit are enhanced from 0.0026 to 0.0040 and from 0.0802 to 0.1141 for myoglobin and creatine kinase (CK)-MB detection, respectively.

Application of Statistical Methods in Quantitative Linguistics Study

  • Choi, Kyung-Ho;Hwang, Yong-Joo
    • Journal of the Korean Data and Information Science Society
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    • v.18 no.2
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    • pp.269-278
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    • 2007
  • Nowadays, from the study of quantitative linguistics, the application of quantitative method is located in a variety of fields as a necessary method. According to this phenomenon, the knowledge of statistical method is requisite for linguists. However, unfortunately, there still remain difficulties for them to acquire the statistical knowledge. So, it is needed for linguists to be helped by statisticians and their active roles. Accordingly, this study is going to emphasizing that statisticians should have more interests in the field of quantitative linguistics. Moreover, it will prove that by using statistical methods, analysis on the linguistic research becomes more objective and scientific.

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Isolation and Development of Quantitative Determination of Torilin from the Torilis Fructus (사상자 (Torilis Fructus)의 지표성분으로 Torilin의 분리 및 함량분석법 개발)

  • Hwang, Eui-Il;Lee, Seong-Kye;So, Seung-Ho;Koo, Bon-Suk;Han, Gyeong-Ho;Kim, Na-Mi
    • Korean Journal of Pharmacognosy
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    • v.38 no.4
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    • pp.321-326
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    • 2007
  • For the propose of the quality control of Torilis Fructus, one major compound was isolated by several column chromatograpies and identified by its spectral data as torilin (8,11-dihydroxy-8-angeloyl-11-acetyl-4-guaien-3-one). A quantitative analysis of torilin using HPLC method showed that the average contents at 230 and 254 nm were $7.167{\pm}0.168mg/g\;and\;7.052{\pm}0.160mg/g$, respectively, in 18 samples collected throughout the regions of Korea and China. This method provided a tool for standardization of the commercial Torilis Fructus.

Prediction of Maintenance Period of Equipment Through Risk Assessment of Thermal Power Plants (화력발전설비 위험도 평가를 통한 기기별 정비주기 예측)

  • Song, Gee Wook;Kim, Bum Shin;Choi, Woo Song;Park, Myung Soo
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.37 no.10
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    • pp.1291-1296
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    • 2013
  • Risk-based inspection (RBI) is a well-known method that is used to optimize inspection activities based on risk analysis in order to identify the high-risk components of major facilities such as power plants. RBI, when implemented and maintained properly, improves plant reliability and safety while reducing unplanned outages and repair costs. Risk is given by the product of the probability of failure (POF) and the consequence of failure (COF). A semi-quantitative method is generally used for risk assessment. Semi-quantitative risk assessment complements the low accuracy of qualitative risk assessment and the high expense and long calculation time of quantitative risk assessment. The first step of RBI is to identify important failure modes and causes in the equipment. Once these are defined, the POF and COF can be assessed for each failure. During POF and COF assessment, an effective inspection method and range can be easily found. In this paper, the calculation of the POF is improved for accurate risk assessment. A modified semi-quantitative risk assessment was carried out for boiler facilities of thermal power plants, and the next maintenance schedules for the equipment were decided.