• Animal Bioscience
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• v.37 no.3
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• pp.522-535
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• 2024

Objective: Transition period is considered from 3 weeks prepartum to 3 weeks postpartum, characterized with dramatic events (endocrine, metabolic, and physiological) leading to occurrence of production diseases (negative energy balance/ketosis, milk fever etc). The objectives of our study were to analyze the periodic concentration of serum beta-hydroxy butyric acid (BHBA), glucose and oxidative markers along with identification, and validation of the putative markers of negative energy balance in buffaloes using in-silico and quantitative real time-polymerase chain reaction (qRT-PCR) assay. Methods: Out of 20 potential markers of ketosis identified by in-silico analysis, two were selected and analyzed by qRT-PCR technique (upregulated; acetyl serotonin o-methyl transferase like and down regulated; guanylate cyclase activator 1B). Additional two sets of genes (carnitine palmotyl transferase A; upregulated and Insulin growth factor; downregulated) that have a role of hepatic fatty acid oxidation to maintain energy demands via gluconeogenesis were also validated. Extracted cDNA (complementary deoxyribonucleic acid) from the blood of the buffaloes were used for validation of selected genes via qRTPCR. Concentrations of BHBA, glucose and oxidative stress markers were identified with their respective optimized protocols. Results: The analysis of qRT-PCR gave similar trends as shown by in-silico analysis throughout the transition period. Significant changes (p<0.05) in the levels of BHBA, glucose and oxidative stress markers throughout this period were observed. This study provides validation from in-silico and qRT-PCR assays for potential markers to be used for earliest diagnosis of negative energy balance in buffaloes. Conclusion: Apart from conventional diagnostic methods, this study improves the understanding of putative biomarkers at the molecular level which helps to unfold their role in normal immune function, fat synthesis/metabolism and oxidative stress pathways. Therefore, provides an opportunity to discover more accurate and sensitive diagnostic aids.

• Journal of Korea Water Resources Association
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• v.52 no.3
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• pp.219-226
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• 2019

Recently, research about Low-Impact Development (LID) techniques has been expanded due to problems with the effects of climate change and urbanization that have been increasing. LID technology is used to control flood damage environmentally to reduce runoff and is reduce runoff on city also restore into previous water circulation system from present developed city. However, studies about quantitative data of LID techniques are insufficient. Therefore in this study, the Curve Number (CN) was calculated with the Planter Box, which is storage type LID technology to conduct the water circulation (infiltration, runoff, overflow) analysis. Rainfall intensity scenario (60.4 mm/hr, 83.1 mm/hr, 97.4 mm/hr, 108.2 mm/hr) about water circulation analysis of Planter Box is selected on the basis of probable rainfall intensity table. According to the experimental results, the storage rate of rainwater in Building Planter Box and Street Planter Box was 43.5% to 52.9% and 33.4% to 39%, respectively. In addition, CN value is estimated to 83 at the Planter box and the runoff reduction effect by applying Horton's infiltration capacity curve showed on 51% to 98%.

• The Journal of the Convergence on Culture Technology
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• v.7 no.3
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• pp.155-161
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• 2021

We surveyed 27 workplaces and 1897 workers and analyzed the correlation between Personal characteristics of workers and Musculoskeletal Symptoms. The presence or absence of Symptoms of Musculoskeletal Disease in workers was based on The Management Target or higher in accordance with the guidelines for The Investigation of Harmful Factors in Musculoskeletal Burdened Work of the Korea Occupational Safety and Health Agency. Personal characteristics were divided into age, work load, housework burden, work experience, leisure type, gender, and marital status. In the survey, correlations were investigated through binominal logistic regression analysis for rank variables of work load, household burden, and work experience, and the significance of the results was confirmed by crosstabulation and chi-square analysis for other nominal variables. And in the case of other variables, there was a slight trend, but it was confirmed that it was not statistically significant. As a result, We confirmed that the incidence rate of Musculoskeletal Disease Symptoms increased as the age of the workers was lower, the higher the workload and housework, if they were women, if they did not engage in leisure activities. However, considering that the results of this study are slightly different as a result of comparing the results of other studies, the data of this study can be used as rough indicators for the prevention of musculoskeletal disorders, but additional research is needed before using it as quantitative indicators.

• Journal of Digital Convergence
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• v.11 no.12
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• pp.599-606
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• 2013

The purpose of this study is to know a clinical usefulness for delineation of articular cartilage compared with 2D TSE-SPIR and 3D FFE-PROSET technique. From January 2013 to september 2013, a total of 30 normal volunteers(12 men and 18 women aged between 35 and 55 years; mean 49.48 years) were studied on a philips 3.0T MRI scanner. As a quantitative analysis, SNRs and CNRs were evaluated by using two methods for delineation of articular cartilage. As a qualitative analysis, image quality was evaluated by special radiological technologist of MRI for image delineation on a three grade. As a results, SNRs and CNRs for articular cartilage were significantly greater for the 3D FFE-PROSET(SNRs: 8.40, 114.02, 9.53, CNRs: 104.49, 139.49) technique compared to 2D TSE-SPIR(SNRs: 4.41, 71.63, 7.34, CNRs: 64.30, 58.41) technique, image quality also was higher for evaluation of 3D FFE-PROSET(2.40) technique(p=0.0021). In conclusion, this study showed that a 3D FFE-PROSET MRI has improved SNRs and CNRs for evaluating of the articular cartilage, these conclusions in the future will be provided useful information in diagnosis of articular cartilage.

• Journal of Broadcast Engineering
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• v.14 no.6
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• pp.796-806
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• 2009

SVC (Scalable Video Coding) is a new video coding standard to provide convergence media service in heterogeneous environments with different networks and diverse terminals through spatial-temporal-quality combined flexible scalabilities. This paper presents the performance analysis on packet loss in the delivery of SVC over IP networks and an efficient adaptation method to packet loss caused by buffer overflow. In particular, SVC with MGS (Medium Grained Scalability) as well as spatial and temporal scalabilities is addressed in the consideration of packet-based adaptation since finer adaptation is possible with a sufficient numbers of quality layers in MGS. The effect on spatio-temporal quality due to the packet loss of SVC with MGS is evaluated. In order to minimize quality degradation resulted by packet loss, the proposed adaptation of MGS based SVC first sets adaptation unit of AU (Access Unit) or GOP corresponding to allowed delay and then selectively discards packets in order of importance in terms of layer dependency. In the experiment, the effects of packet loss on quantitative qualities are analyzed and the effectiveness of the proposed adaptation to packet loss is shown.

• Journal of Digital Convergence
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• v.12 no.2
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• pp.143-149
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• 2014

Currently, despite the quantitative growth of domestic journal, objective and metric criterion to evaluate the contents and quality of those journals is inadequate. As a result, depending on a foreign citation index like SCI to evaluate the research result is causing some problems such as, thesis of an excellent standard being presented and published in foreign countries, thus, neglecting journals written in Korean. Hereat, the Korea Citation Index(KCI) is constructing a database of the journals published by academic associations; scientific paper information, articles information, and bibliographic, analyzing the quoting relation. Consequently, KCI is providing the basic information and the corresponding quoting relations of journals and papers on its webpage. This study compares the impact level of domestic accounting related journals by KCI and analyzes the network among journals using the cross-citation frequency from a social network analysis point of view. As a result, Accounting-related journals are now more desirable than the location in order to have a variety of interdisciplinary research needs to be encouraged. Through this exchange of other disciplines and actively made, which is the phase of apparent accounting-related journals expect to be greatly enhanced looks.

• Journal of Internet Computing and Services
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• v.14 no.5
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• pp.119-128
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• 2013

As ICT technology becomes advanced, the importance of future internet is emphasized and in part of that, M2M (Machine-to Machine communications) is magnified in terms of importance and usage in public and private sector. M2M is emerging as a next generation strategic industry but there is no existing analyzed data or market classification, so it disrupts establishing policies on the M2M industry. As the technology is progressing, the evolution from M2M to IoT (Internet of Things) has started and many countries actively try to find technological trend through market analysis in order to develop new growth engine. Therefore, in order to strengthen competitiveness, we should secure differentiated capabilities in industry and service. This article examines Korea's domestic market and international market trends in IoT and analyses the economic impact of the IoT industry using quantitative methodology and evaluates relations between the IoT industry and other relevant industries. As a result, the effect of IoT industry on production inducement is KRW474.6 billion; the effect on value-added inducement is KRW314.7 billion; and it is measured that 3,628 jobs will be created by the IoT industry.

• The Journal of the Convergence on Culture Technology
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• v.6 no.4
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• pp.621-626
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• 2020

The incidence of colorectal cancer (CRC) in Korea has been gradually increased and it has been reported that dietary life is highly associated with the development of CRC. To investigate dietary attitudes and nutritional risk factors for CRC, we analyzed food intake of 34 patients diagnosed with CRC within 1 year and 51 subjects without gastrointestinal diseases as a control reside in Daegu·Gyeongbuk Area using semi-quantitative food frequency questionnaire. The results showed that dietary regularity and variety of food intake in control subjects was better than CRC patients whereas, CRC patients eat more frequently animal and vegetable protein foods, fried foods, green and yellow vegetables, and fruits than control subjects. Nutrient intake analysis showed that Vitamin A, E, K, C, sodium, magnesium, iodine, and cholesterol intake of CRC patients was higher than control subjects. Especially, after adjusting age and sex, regression analysis showed that Vitamin K (OR = 1.022, 95% Cl 1.003-1.043, p = 0.026) and sodium (OR = 1.001, 95% Cl 1.000-1.002, p = 0.032) were identified as risk factors for CRC. In the future, verification of the relationship between these nutrients and CRC risk and appropriate nutrient education will be needed for the prevention of CRC.

• Journal of Ginseng Research
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• v.45 no.5
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• pp.583-590
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• 2021

Background: Gintonin, isolated from ginseng, acts as a ginseng-derived lysophosphatidic acid (LPA) receptor ligand and elicits the [Ca²⁺]_i transient through six LPA receptor subtypes (LPARSs). However, the long-term effects of gintonin-enriched fraction (GEF) on the gene expression of six LPARSs remain unknown. We examined changes in the gene expression of six LPA receptors in the mouse whole brain, heart, lungs, liver, kidneys, spleen, small intestine, colon, and testis after long-term oral GEF administration. Methods: C57BL/6 mice were divided into two groups: control vehicle and GEF (100 mg/kg, p.o.). After 21-day saline or GEF treatment, total RNA was extracted from nine mouse organs. Quantitative-real-time PCR (qRT-PCR) and western blot were performed to quantify changes in the gene and protein expression of the six LPARSs, respectively. Results: qRT-PCR analysis before GEF treatment revealed that the LPA6 RS was predominant in all organs except the small intestine. The LPA2 RS was most abundant in the small intestine. Long-term GEF administration differentially regulated the six LPARSs. Upon GEF treatment, the LPA6 RS significantly increased in the liver, small intestine, colon, and testis but decreased in the whole brain, heart, lungs, and kidneys. Western blot analysis of the LPA6 RS confirmed the differential effects of GEF on LPA6 receptor protein levels in the whole brain, liver, small intestine, and testis. Conclusion: The LPA6 receptor was predominantly expressed in all nine organs examined; long-term oral GEF administration differentially regulated LPA3, LPA4, and LPA6 receptors in the whole brain, heart, lungs, liver, kidneys, small intestine, and testis.

• The Journal of the Convergence on Culture Technology
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• v.4 no.4
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• pp.77-87
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• 2018

The study was a mixed design study that analyzed the effects of developing and applying a program to improve pregnancy recognition for severe low fertility. The study period was from April 1, 2018, to October 26, 2018, and the participants included 16 women of 19~21 age who lived in M City and M Gun. The process of program development is based on Dorothy Johnson 's theory of behavior system to induce change of perception, and reference literature review and national policy report. The program developed through the literature was finally developed by examining the experts panel discussion after deriving causes and alternatives for low fertility from 25 fertility women. The contents of program consist of three areas. Quantitative research results were analyzed using Shapiro Wilk and Wilcoxon sign rank using SPSS 18.0, and qualitative research results were analyzed using focus group. As a result of study, the perception of pregnancy increased significantly (P<0.01) with statistical significance as pre-experimental (M=3.21, SD=.342), post-experimental (M=4.46, SD=.398) and the result of content analysis appeared three themes as , , . In conclusion, the program was effective in improving the recognition of pregnancy for young women.