• Title/Summary/Keyword: Quantification analysis

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Development and validation of an analytical method for the quantification of 2,6-diisopropylnaphthalene in agricultural products using GC-MS/MS

  • Lee, Han Sol;Park, Ji-Su;Lee, Su Jung;Shin, Hye-Sun;Chung, Yun mi;Choi, Ha na;Yun, Sang Soon;Jung, Yong-hyun;Oh, Jae-Ho
    • Analytical Science and Technology
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    • v.34 no.1
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    • pp.1-8
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    • 2021
  • An analytical method was developed and optimized for the quantification of a plant growth regulator, 2,6-diisopropylnaphthalene (2,6-DIPN), in agricultural products using gas chromatography-tandem mass spectrometry. The samples were extracted, partitioned, and were purified using a Florisil® cartridge. To validate the analytical method, its specificity, linearity, limit of detection (LOD) and limit of quantification (LOQ) of the instrument, LOQ of the analytical method (MLOQ), accuracy, and repeatability were considered. The method displayed excellent results during validation, and is suitable for the determination and quantification of the low residual levels of the analyte in the agricultural samples. All of the results with the optimized method were satisfactory and within the criteria ranges requested in the Codex Alimentarius Commission guidelines and the Ministry of Food and Drug Safety guidelines for pesticide residue analysis. The developed method is simple and accurate and can be used as a basis for safety management of 2,6-DIPN.

An Analysis of Ecosystem Service's trade-off through Systems Thinking (시스템 사고를 통한 생태계서비스의 trade-off 관계 고찰)

  • Ham, Eun Kyung;Kim, Min;Chon, Jinhyung
    • Korean System Dynamics Review
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    • v.16 no.2
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    • pp.75-100
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    • 2015
  • The purpose of this study is to analyze causation of Ecosystem service's trade-off(ES trade-off) and to establish baseline data for wise spatial planning and management. In order to understand why and how ES trade-off occurs, systems thinking and causal loops were employed. The causal loop of ecosystem service creation cycle includes profits quantification process, decision making process, spatial planning and management process, and ecosystem services creation process. The profits quantification process has a limitation that all ecosystem service categories were not included in profits quantification, because quantification method for cultural services is insufficient. These problems led to unequal discussion opportunity in decision making process. ES trade-off occurs through transition of ecosystem function in spatial scale and temporal scale. In spatial scale, land-use variation and resource-use variation contribute to change an ecosystem function for different ES category by spatial planning and management. In temporal scale, a change of an ecosystem function for different ES category is influenced by ecological succession, seasonal change and land cover variation, which are parameter from environmental features. This study presented that spatial planning and management should ecosystem service assessment in order to enhance balanced ecosystem services.

Modification of the fast fourier transform-based method by signal mirroring for accuracy quantification of thermal-hydraulic system code

  • Ha, Tae Wook;Jeong, Jae Jun;Choi, Ki Yong
    • Nuclear Engineering and Technology
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    • v.49 no.5
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    • pp.1100-1108
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    • 2017
  • A thermal-hydraulic system code is an essential tool for the design and safety analysis of a nuclear power plant, and its accuracy quantification is very important for the code assessment and applications. The fast Fourier transform-based method (FFTBM) by signal mirroring (FFTBM-SM) has been used to quantify the accuracy of a system code by using a comparison of the experimental data and the calculated results. The method is an improved version of the FFTBM, and it is known that the FFTBM-SM judges the code accuracy in a more consistent and unbiased way. However, in some applications, unrealistic results have been obtained. In this study, it was found that accuracy quantification by FFTBM-SM is dependent on the frequency spectrum of the fast Fourier transform of experimental and error signals. The primary objective of this study is to reduce the frequency dependency of FFTBM-SM evaluation. For this, it was proposed to reduce the cut off frequency, which was introduced to cut off spurious contributions, in FFTBM-SM. A method to determine an appropriate cut off frequency was also proposed. The FFTBM-SM with the modified cut off frequency showed a significant improvement of the accuracy quantification.

Development of an uncertainty quantification approach with reduced computational cost for seismic fragility assessment of cable-stayed bridges

  • Akhoondzade-Noghabi, Vahid;Bargi, Khosrow
    • Earthquakes and Structures
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    • v.23 no.4
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    • pp.385-401
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    • 2022
  • Uncertainty quantification is the most important challenge in seismic fragility assessment of structures. The precision increment of the quantification method leads to reliable results but at the same time increases the computational costs and the latter will be so undesirable in cases such as reliability-based design optimization which includes numerous probabilistic seismic analyses. Accordingly, the authors' effort has been put on the development and validation of an approach that has reduced computational cost in seismic fragility assessment. In this regard, it is necessary to apply the appropriate methods for consideration of two categories of uncertainties consisting of uncertainties related to the ground motions and structural characteristics, separately. Also, cable-stayed bridges have been specifically selected because as a result of their complexity and the according time-consuming seismic analyses, reducing the computations corresponding to their fragility analyses is worthy of studying. To achieve this, the fragility assessment of three case studies is performed based on existing and proposed approaches, and a comparative study on the efficiency in the estimation of seismic responses. For this purpose, statistical validation is conducted on the seismic demand and fragility resulting from the mentioned approaches, and through a comprehensive interpretation, sufficient arguments for the acceptable errors of the proposed approach are presented. Finally, this study concludes that the combination of the Capacity Spectrum Method (CSM) and Uniform Design Sampling (UDS) in advanced proposed forms can provide adequate accuracy in seismic fragility estimation at a significantly reduced computational cost.

Quantification Method of Kinesthetic Sense of Arm with Compensation for Individual Difference (개인차 보상을 고려한 팔운동감의 정량화 방법)

  • 정웅철;송재복;김용일
    • Journal of the Korean Society for Precision Engineering
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    • v.17 no.2
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    • pp.227-234
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    • 2000
  • The human sensibility caused by the motion of an object grasped by a human operator is defined as kinesthetic sense of arm. Due to nonlinearity and ambiguity of human sense, there is no absolute standard for quantification of kinesthetic sense. In this research, a so-called 2-dimensional arm motion generator is developed to present various mechanical impedance (i.e., stiffness or damping) characteristics to a human arm. The kinesthetic words representing arm kinesthetic sense are selected and then the subject's satisfaction levels on these words for given impedance values are measured and processed by the SD method and factor analysis. In addition, the quantification method using neural network is proposed to take into account the individual difference between the mean sensibility and each subject's sensibility. Through this proposed algorithm, the sensibility of human motion described qualitatively can be converted into engineering data ensuring objectivity, reproducibility, and universality.

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Characteristics of health lifestyle patterns by the quantification method (수량화 방법을 이용한 건강행태 유형의 특성에 관한 연구)

  • Lee, Soon-Young;Kim, Seon-Woo
    • Journal of Preventive Medicine and Public Health
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    • v.31 no.1 s.60
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    • pp.72-81
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    • 1998
  • The purpose of this study was to investigate the relation between health behavior patterns and demographic, socio-economic characteristics, health status, health information in Korea. The quantification method through canonical correlation analysis was conducted to the data from Korea National Health Survey in 1995, which consisted of 5,805 persons. The health lifestyle patterns were quantified as good diet lifestyle, passive lifestyle to the negative direction and drinker lifestyle, smoker lifestyle, hedonic lifestyle and fitness lifestyle to the positive direction. The covariate were related to health lifestyle patterns in the order of sex, age, marital status, occupation, health information, economic status, level of physical labour and health status. Characteristics of male, age below 50, married, blue colored worker, no health information, low in economic status, heavy level of physical labour, and poor in health status were positively related to drinker lifestyle, smoker lifestyle, hedonic lifestyle, fitness lifestyle sequentially.

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Detection and Quantification of Methanogenic Communities in Anaerobic Processes Using a Real-Time PCR

  • Yu Youngseob;Hwang Seokhwan
    • Proceedings of the Microbiological Society of Korea Conference
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    • 2003.05a
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    • pp.118-121
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    • 2003
  • A method for detection and quantification of aceticlastic methanogens using a real-time PCR with a TaqMan probe was developed. Two sets of primers and probes targeting the family Methanosarcinaceae and Methanosaetaceae were designed by using the Ribosormal Database Project (RDP) II, and softwares for phylogenetic probe design and sequence analysis. Target-group specificity of each set of primers and probe was verified by testing DNAs isolated from pure cultures of 28 archaeal strains purchased from DSMZ. Cell numbers in the 28 archaeal cultures and in the samples from anaerobic processes were quantified using a real-time PCR with the sets of primers and probe. In conclusion, the real-time PCR assay was very specific for the corresponding target methanogenic family and was proved to be a powerful method for quantification of aceticlastic methanogens in anaerobic processes.

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The quantification of photon counts using the concept of candela (Candela 개념의 광량정량화 활용에 관한 연구)

  • Kim, Hyeon Sik;Choi, Eun Seo;Lee, Byeong-Il
    • Journal of Integrative Natural Science
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    • v.1 no.1
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    • pp.1-4
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    • 2008
  • We developed quantification method based on the concept of candela in physics. The measurement of fluorescence signal from a nude mouse in the research of molecular biology. In the measurement of the optical signal with CCD, the quantification method for photon counts based on bio-luminescence imaging technique can provide comparative reference data. In this paper, we described theoretical derivation of our proposed concept. We hope this method could be a useful standard reference for quantitative date analysis in optical imaging.

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A Study on the Quantification of Information Security Level (정보보안수준 계량화 연구)

  • Kim, Hyun-Soo
    • Asia pacific journal of information systems
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    • v.9 no.4
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    • pp.181-201
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    • 1999
  • This study presents an information security level index and a quantification scheme. A comprehensive survey on previous researches in information security checklists has been performed. A candidate indicator list for information security level has been developed, Desirability of each indicator has been tested by 4 criteria, They are general validity, relative importance, probability of accident and impact of accident. 67 experts' opinion has been collected and analysed. The result shows that selected indicators are a very good candidate set for the determination of information security level. A factor analysis shows indicators are well structured. There exists strong correlation between validity and probability, validity and impact, and importance and probability. A quantification scheme of information security index has been developed by experts' judgement and statistical tests.

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New Method for Simultaneous Quantification of 12 Ginsenosides in Red Ginseng Powder and Extract: In-house Method Validation

  • In, Gyo;Ahn, Nam-Geun;Bae, Bong-Seok;Han, Sung-Tai;Noh, Kil-Bong;Kim, Cheon-Suk
    • Journal of Ginseng Research
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    • v.36 no.2
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    • pp.205-210
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    • 2012
  • For quality control of components in Korean red ginseng powder and extract, a new method for simultaneous quantification of 12 ginsenosides ($Rg_1$, Re, Rf, $Rh_1$, $Rg_2$[S], $Rg_2$[R], $Rb_1$, Rc, $Rb_2$, Rd, $Rg_3$[S], and $Rg_3$[R]) was studied. Compared to the official method for quantification of marker substances (ginsenosides $Rg_1$ and $Rb_1$), the proposed methods were guaranteed by in-house method validation. Several criteria such as linearity, specificity, precision and accuracy were evaluated. For red ginseng powder, recovery (averaging 95% to 105%) was calculated, and analysis of variance was carried out to estimate the relative standard deviation (0.20% to 2.12%). For red ginseng extract, the average recovery rate was 90% to 99% and the relative standard deviation was 0.39% to 2.40%. These results indicate that the proposed method could be used in the laboratory for determination of 12 ginsenosides in red ginseng powder and extract. In addition, this method was found to be suitable for quality control of ginseng products and potentially offer time and cost benefits.