• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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• pp.244.1-244.1
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• 2003

We aimed at determining bioavailability of clonazepam, an anxiolytic drug, and developing a simple analysis in human blood using HPLC. A rapid and sensitive HPLC method was developed and validated using reverse-phase C18 column with retension time and limit of quantification of clonazepam being 2.58 min and 5hg/ml, respectively. Quantification was performed at 235 nm with p-hydroxybenzoic acid ethyl ester as internal standard. The method involved a simple extraction. In order to study blood level profile in time, sight volunteers were enrolled and orally took 6 mg clonazepam once. (omitted)

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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• pp.240.2-240.2
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• 2003

We aimed at determining bioavailability of procainarnide HCl, an antiarrhythmic drug, and developing a simple analysis in human blood using HPLC. A rapid and sensitive HPLC method was developed and validated using reverse-phase C18 column with retension time and limit of quantification of procainamide HCl being 2.58 min and 50ng/ml, respectively. Quantification was performed at 275 nm with caffeine as internal standard. The method involved a simple extraction. In order to study blood level profile in time, eight volunteers were enrolled and orally took 250 mg procainamide HCl once. (omitted)

• 한국경영과학회:학술대회논문집
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• 대한산업공학회/한국경영과학회 1990년도 춘계공동학술대회논문집; 한국과학기술원; 28 Apr. 1990
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• pp.272-288
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• 1990

The uncertainty quantification process in probabilistic Risk Assessment usually involves a specification of the uncertainty in the input data and the propagation of this uncertainty to the final risk results. The distributional sensitivity analysis is to study the impact of the various assumptions made during the quantification of input parameter uncertainties on the final output uncertainty. The uncertainty importance of input parameters, in this case, should reflect the degree of changes in the whole output distribution and not just in a point estimate value. A measure of the uncertainty importance is proposed in the present paper. The measure is called the distributional sensitivity measure(DSM) and explicitly derived from the definition of the Kullback's discrimination information. The DSM is applied to three typical discrimination information. The DSM is applied to three typical cases of input distributional changes: 1) Uncertainty is completely eliminated, 2) Uncertainty range is increased by a factor of 10, and 3) Type of distribution is changed. For all three cases of application, the DSM-based importance ranking agrees very well with the observed changes of output distribution while other statistical parameters are shown to be insensitive.

• Mass Spectrometry Letters
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• 제14권3호
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• pp.104-109
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• 2023

Anabolic-androgenic steroids (AAS) are used illegally to enhance muscle development and increase strength and power. In this study, a reliable, and sensitive quantitative method was developed and validated using heptafluorobutyric acid anhydride (HFPA) derivatives for the simultaneous detection of prohibited AAS (testosterone [TS], boldenone [BD], 5α-estrane-3β,17α-diol [EAD]) using gas chromatography-tandem mass spectrometry (GC-MS/MS). For processing the samples, solid phase extraction, methanolic hydrolysis, and liquid-liquid extraction were used. For detection using mass spectrometry, the multiple reaction monitoring (MRM) mode was used with the electron ionization (EI) positive mode. The method was evaluated for selectivity, linearity, lower limit of quantification, intra- and inter-day precision, accuracy, and stability. The results showed that the method was accurate and reproducible for the quantitation of the three steroids. The developed method was finally applied to the analysis of a suspect gelding urine sample received from the Asian Quality Assurance Program (AQAP).

• 한국건축시공학회:학술대회논문집
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• 한국건축시공학회 2023년도 가을학술발표대회논문집
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• pp.249-250
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• 2023

The vulnerability factor analysis and risk quantification model for aging buildings presented in this study can be utilized by governmental agencies such as the Facility Safety Foundation, the Ministry of Land, Infrastructure and Transport, and various local governments. Policymakers can use this to supplement inadequacies in existing checklists, and it is expected that they can proactively prevent risks by evaluating dangers based on specific aging characteristics of buildings.

• 한국진공학회지
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• 제2권3호
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• pp.384-390
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• 1993

A number of different thin-film analytical method using electron spectroscopies are reviewed and evaluated. Results from various kinds of films (e.g. superconductive, electron-emissive, amorphous, rare-earth containing, etc.) are given for illustration. The existing quantification problems from this technology and some approaches for solving them are also discussed.

• 한국작물학회지
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• 제49권spc1호
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• pp.90-96
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• 2004

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2006년도 춘계학술대회논문집
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• pp.452-452
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• 2006

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2013년도 추계학술대회 논문집
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• pp.64-65
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• 2013

• 산업경영시스템학회지
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• 제22권52호
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• pp.241-246
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• 1999

In this study, to specify an evaluation of human sensibility, the types of color, intensity of illuminations and lights consisting work environmental condition are decided, and image data from examining the change of human sensibility followed by changes of the above three conditions are obtained. Using the factor analysis and quantification theory in multi-variate analysis type of Sensibility Ergonomics, determinating the structure of factors, specifying the relations of environmental conditions and factors can be done so that the structure of image on human sensibility space with the change of environmental conditions is analyzed.