• Title/Summary/Keyword: Quality of clinical trial

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Analysis of Choice factors of Korean Medicine and Pain Assessment - Using a Korean Longitudinal Study of Ageing(KLoSA) - (한의의료 이용자의 통증 평가와 한의의료 이용 영향요인 분석 - 고령화 패널을 이용하여 -)

  • Jang, Hye-Kyoung;Jung, In Chul;Park, Yang Chun;Park, So Jung
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.32 no.6
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    • pp.411-417
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    • 2018
  • Last year, the elderly population aged 65 years and over exceeded 14.2 percent of the total population, and Korea has entered the ageing society. At the same time, social interest in improving the health level and quality of life in the elderly has also increased. In particular, pain is one of the most common diseases experienced by middle-aged and elderly people and is one of the factors that closely affect the quality of life. The purpose of this study was to analyze the factors affecting the pain level and pain region of Korean medicine users and the use of Korean medicine in the Korean middle aged and elderly using the 6th Korean Longitudinal Study of Ageing (KLoSA) panel. As a result, the main influencing factors of Korean medical care were subjective factors such as gender, subjective health status, and education level. In particular, half of the middle-aged and elderly who used Korean medicine experienced back and knee pain, and generally complained of low level of pain. This study suggests the need for research and development of Korean medicine that can control and relieve the pain of the middle-aged and elderly.

Chuna Manual Therapy for Functional Dyspepsia : A Systematic Review and Meta-analysis (기능성 소화불량증에 대한 추나요법의 효과 : 체계적 문헌고찰과 메타분석)

  • Heo, In;Shin, Byung-Cheul;Hwang, Eui-Hyoung;Hwang, Man-Suk;Kim, Byung-Jun;Kim, So-Yeon;Heo, Kwang-Ho
    • The Journal of Churna Manual Medicine for Spine and Nerves
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    • v.10 no.1
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    • pp.1-14
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    • 2015
  • Objectives : To evaluate the evidence supporting the effectiveness of Chuna manual therapy for functional dyspepsia. Methods : We conducted search across the 3 electronic databases (Pubmed, CAJ and Oasis) to find all of randomized controlled clinical trials(RCTs) that used Chuna manual therapy as a treatment for functional dyspepsia. The methodological quality of each RCT was assessed using the Cochrane risk of bias tool. Results : Thirteen RCTs met our inclusion criteria. The meta-analysis showed positive results for the use of Chuna manual therapy combined with medication treatments in terms of the efficacy rate when compared to medication treatments alone. Positive results were also obtained, in terms of the efficacy rate, when comparing Chuna manual therapy combined with medication plus specific electromagnetic therapy to medication treatments alone. Conclusions : Our systematic review found encouraging but limited evidence of Chuna manual therapy for functional dyspepsia. However, to obtain stronger evidence without the drawbacks of trial design and the quality of studies, we recommend sham-controlled RCTs or comparative effectiveness research to test the effectiveness of Chuna manual therapy.

Acupuncture Treatment for Shoulder Impingement Syndrome: A Review of Randomized Controlled Trials

  • Park, Jae Eun;Kim, Woo Young;Lee, Soo Jin;Oh, Da Yoon;Lee, Min Cheol;Jeon, Myung Kyu;Kim, Hyeon Jin;Ahn, Jae Young;Yang, Su Hyeon;Choi, Yun Young;Shin, Na Young;Nam, Hye Jin
    • Journal of Acupuncture Research
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    • v.38 no.3
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    • pp.175-182
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    • 2021
  • To evaluate the effectiveness of acupuncture treatment for shoulder impingement syndrome (SIS) a literature review was conducted of randomized controlled trials (RCTs) where acupuncture was used as an intervention for patients diagnosed with SIS. Relevant clinical studies (N = 181) were retrieved from several databases based on the inclusion/exclusion criteria, and the interventions and results were analyzed. Six RCTs were selected to review based on the inclusion and exclusion criteria. In all 6 studies, the acupuncture treatment group showed significant positive changes in indicators evaluating pain, disability, and quality of life. A significant decrease in the evaluation indicators (Shoulder Pain and Disability Index, numeric rating scale, Visual Analogue Scale, Constant Murley Shoulder Assessment Score, patient's global assessment, and doctor's global assessment) and a significant increase in the questionnaire scores (UCLA, AL-score, EuroQol 5 Dimension Self-Report Questionnaire, and disabilities of the arm, shoulder, and hand) were observed. In addition, 1 study showed similar improvements in pain and quality of life measures in the acupuncture group and corticosteroid injection group. No major side effects were reported. Acupuncture may be an effective and safe treatment for SIS however, further RCTs are required.

Electroacupuncture for Carpal Tunnel Syndrome: A Review of Randomized Controlled Trials

  • Park, Cheol Woo;Lim, Min Ji;Lee, Se Won;Yi, Yeon Hoo;Song, Da Woon;Yu, Sang Gu;Kim, Min Ju;Oh, Da Yoon;Choi, Hyo Jung;Ju, Ah Ra
    • Journal of Acupuncture Research
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    • v.39 no.2
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    • pp.96-104
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    • 2022
  • This study aimed to examine the clinical efficacy of electroacupuncture treatment for carpal tunnel syndrome by reviewing published randomized controlled trials. Among the 186 studies retrieved from 7 online databases (PubMed, Cochrane library, CNKI, NDSL, RISS, OASIS, KMbase) on October 29, 2021, 4 studies were selected according to the inclusion, exclusion criteria, and were evaluated using risk of bias. Control groups for electroacupuncture were wearing a splint at night, traditional acupuncture, and medication. Methods such as total effective, functional status scale, symptom severity scale, electromyography, tip pinch strength, visual analogue scale, numeric rating scale, and ultrasound were used to evaluate the therapeutic effect. Electroacupuncture was reported to have significant treatment results compared with the control group in methods such as total effectiveness, electromyography, and tip pinch strength. However, the quality of the studies (using risk of bias) does not allow reliable conclusions to be made. Many high quality (low risk of bias) randomized controlled trials are needed to examine the efficacy of electroacupuncture treatment for carpal tunnel syndrome.

Daoyin Exercise Therapy for Stroke : A Systematic Review (뇌졸중에 대한 도인 운동요법의 효과: 체계적 문헌 고찰)

  • Lee, Sang-Hyun;Shin, Byung-Cheul;Hwang, Eui-Hyoung;Heo, In;Park, Sun-Young;Hwang, Man-Suk
    • The Journal of Churna Manual Medicine for Spine and Nerves
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    • v.14 no.2
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    • pp.29-42
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    • 2019
  • Objectives : This study aimed to review the effects of Daoyin exercise on stroke patients in clinical studies. Methods : In this study, we reviewed 11 electronic databases (CAJ, EMBASE, Cochrane Library, Web of Science, Pubmed, RISS, Dbpia, NDSL, KISTI, KISS, KMBASE) on October 27, 2019. We included only randomized controlled trials (RCTs) which evaluated the effect of Daoyin exercise on stroke patients. The methodological quality of the included studies was checked using the Cochrane risk of bias tool. Results : After screening the papers, eleven RCTs fulfilled the inclusion criteria. The results of the meta-analysis showed that Daoyin exercise improves the measurement value on the Fugl-Meyer Assessment, Modified Barthel Index and National Institutes of Health Stroke Scale in stroke patients. Conclusions : We concluded that Daoyin exercise has therapeutic effects in functional recovery and in enhancing the independence of daily living activities for stroke patients. However, the quality of the original articles was low and the number of papers included were few. Thus, to confirm these results, further well-designed RCTs should be conducted.

Design and Implementation of CDA Based PACS for Optimized Metadata Extraction (최적화된 메타데이터 추출물 위한 CDA 기반의 의료영상전달시스템 설계 및 구현)

  • Kim Sun-Chil;Cho Hune;Kwak Yun-Sik;Kim Il-Kon;Kim Hwa-Sun
    • The Transactions of the Korean Institute of Electrical Engineers D
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    • v.54 no.5
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    • pp.315-323
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    • 2005
  • The recent development of embodiment technology of the medical images makes most medical institutions introduce PACS in haste. However, while many older HIS and PACS systems are not yet capable of some of the integration, several new systems are moving rapidly in that direction. Typical PACS system architecture begins with the HIS since this is where the correct patient demographic information and in many cases the orders originate. So, PACS developed convenience of users and to satisfy user's demand because of financial limitations and administrator-oriented considerations in the process of development. Therefore, we have developed a CDA (Clinical Document Architecture) based PACS with HIS, by which we can search and refer to the patient's medical images and information with few restrictions of time and space for diagnosis and treatment. Target model of this research limited to 135 of hospital have 200 beds. We'll make more effort to develop the application which insures the better quality and information of medical images. Medical Image History manages the patient's image files and various medical informations like film chart in connection with time. This trial will contribute to the reduction of the financial loss caused by unnecessary devices and improve the quality in the medical services. The demand on the development of the program which refers to the medical data quickly and keeps them stable will be continued by the medical institute. This will satisfy the client's demand and improve the service to the patients in that the program will be modified from the standpoint of the users.

Effects of Microcurrent on Inflammatory Musculoskeletal Diseases: A Meta-Analysis (염증성 근육뼈대계 질환에 대한 미세전류의 효과: 메타분석)

  • Lee, Jeongwoo;Ko, Un;Doo, Yeongtaek
    • Journal of The Korean Society of Integrative Medicine
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    • v.8 no.4
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    • pp.1-11
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    • 2020
  • Purpose : The purpose of this meta-analysis was to examine the effects of microcurrent on inflammatory musculoskeletal diseases. Methods : Domestic databases (RISS, NDSL, KISS, DBpia, and Kmbase) were searched for studies that conducted clinical trials associated with microcurrent and its impact on inflammatory musculoskeletal diseases. A total of 606 studies published between 2002 and 2019 were identified, with 8 studies satisfying the inclusion data. The studies were classified according to patient, intervention, comparison, and outcome (PICO). The search outcomes were items associated with blood component, pain, and function. The 8 studies that were included in the study were evaluated using R meta-analysis (version 4.0). The quality of 7 randomized control trials was evaluated using Cochrane risk of bias (ROB). The quality of 1 non-randomized control trial was evaluated using risk of bias assessment tool for non-randomized studies (RoBANS). Effect sizes were computed as the corrected standard mean difference (SMD). A random-effect model was used to analyze the effect size because of the high heterogeneity among the studies. Egger's regression test was carried out to analyze the publishing bias. Results : The following factors had a large effect size involving microcurrent on inflammatory musculoskeletal diseases: blood component (Hedges's g=-2.46, 95 % CI=-4.20~-0.73), pain (Hedges's g=3.51, 95 % CI=2.44~4.77), and function (Hedges's g=3.06, 95 % CI: 1.53~4.58). Except for function (t=1.572, p=.191), Egger's regression test showed that the publishing bias had statistically significant differences. Conclusion : This study provides evidence for the effectiveness of microcurrent on inflammatory musculoskeletal diseases in terms of blood component, pain, and function. However, due to the small sample sizes used in the included studies, the results of our study should be interpreted cautiously, especially considering the publishing bias.

Effect of Dietary Inclusion of Dehydrated Food Waste Products on Taiwan Native Chicken (Taishi No. 13)

  • Chen, Kuo-Lung;Chang, Hwang-Jen;Yang, Ching-Ke;You, Shanq-Huei;Jenq, Horng-Der;Yu, Bi
    • Asian-Australasian Journal of Animal Sciences
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    • v.20 no.5
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    • pp.754-760
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    • 2007
  • The effect of dehydrated food waste product (DFWP) inclusion in diets of Taiwan native chickens on the growth performance, carcass traits, clinical blood chemistry and nutrient digestibility was investigated with 320 male Taishi Native Chickens (Taishi No. 13). They were randomly allocated into four levels of DFWP inclusion (0, 5, 10, or 20%) treatment. Each treatment had 80 chickens with four replicates. At 15 weeks of age, 8 chickens were selected from each group for the nutrient digestibility trial. The results showed that body weight gain during the 0 to 4 week period decreased as the feed intake and feed conversion rate (FCR) increased linearly with increasing level of DFWP inclusion. During the 4 to 8 week period, greater body weight gains were recorded for the birds on the 5% DFWP inclusion level than for the control (p<0.05). During 8 to16 weeks, the feed intake and FCR increased linearly (p<0.05). Interestingly too, results of the carcass analysis showed that DFWP inclusion up to 20% in the diet significantly decreased the relative abdominal fat weight but increased the relative proventriculus and gizzard weights of the birds. However, other carcass parameters, meat quality and sensory scores were not significantly influenced by the dietary DFWP inclusion levels (p>0.05). Higher serum aspartate aminotransferase, ${\gamma}$-glutamyltransferase activity and crude protein digestibility, and lower gross energy digestibility were observed in the 20% DFWP group compared to the control (p<0.05). Dietary DFWP inclusion was inappropriate during the 0 to 4 week period. During 4 to 8 weeks, there was no adverse effect on chicken performance in the 20% group. There was no disadvantage on carcass properties and in the meat panel test. This result would not affect consumer determination.

A Study on Factors Influencing Medical Treatment Decision-Making for Overactive Bladders in Female Patients over 40 - Data from Clinical Trial Participants - (40세 이상 과민성방광 여성 환자의 의료이용 결정요인에 관한 연구 - 임상시험 참여자를 중심으로 -)

  • Ahn, In-Suk;Kim, Dong-Il;Choi, Min-Sun
    • The Journal of Korean Obstetrics and Gynecology
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    • v.26 no.1
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    • pp.69-81
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    • 2013
  • Purpose: The aim of this study is to determine associated factors affecting the utilization of Medical Care for an overactive bladder. Methods: Total 114 women with overactive bladder participated in this study. Patients were categorized in two groups, the patients with treatment experiences for an overactive bladder(n=40) and without treatment experiences for an overactive bladder(n=74). Patients completed Overactive Bladder Severity Score, Beck Depression Inventory, King's Health Questionnaire, and questionnaires on treatment experience. The results were analysed using SPSS for Windows 12.0k. All statistical tests were two-sided with a p-value < 0.05 being significant. Results: Patients with treatment experience had a greater score on KHQ, OABSS, BDI and had longer symptom duration period than those without treatment experience. And only Impact of Life(P=0.004), Role Limitation(P=0.004), Social Limitation(P=0.007), Emotion(P=0.035), Sleep/Energy(P=0.001), Incontinence Severity Measures(P=0.012) among KHQ domains were statistically significant difference between two groups. Conclusions: The most influencing factor associated with utilization of Medical Service in overactive bladder is the impact of the patient's quality of life.

Consumer Perception and Evaluation of Cynanchi Atrati Radix Fermented Oriental Cosmetics for Skin Whitening (피부 미백용 백미발효 한방 화장품에 대한 소비자 인식과 평가)

  • Son, Chang-gue;Jang, Eun-su;Lee, Sam-keun;Barng, Kee-jung
    • Journal of Fashion Business
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    • v.23 no.5
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    • pp.137-150
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    • 2019
  • This study aimed to provide consumer perception and evaluation of natural Cynanchi Atrium Fermented Original Cosmetics for Skin Whitening that can improve skin by using oriental medicinal ingredients. The product was applied three times a day for two weeks by a total of 60 users who agreed to participate in a clinical trial assessing the usability and skin sensitivity to extracts that had already completed component safety testing. This study subjects reported which images were most reminiscent of Korea. They preferred products that bore Korean images because they felt trust and recognized that the quality of the cosmetics was excellent. The responses also showed that many consumers were willing to buy a product, even though it was luxurious, elegant, and expensive. The cognitive evaluation of Original Cosmetics was high and showed that the quality was likely to be good. The usability and CMF(Color, Material, Finishing) evaluation of Original Cosmetics showed good product the product is long-lasting and tightened and moisturized skin naturally. They are think about that this product it has moisturizing effects and good application for use, so it is light and soft to use. And had a whitening effect. It was intended to assist in the development of products that meet consumers' desires and expectations for safe, healthy, and beautiful skin by developing a skin whitening Original Cosmetics prototype that can inhibit the production of melanin and tyrosinase activity safely and effectively.