• 한국소성가공학회:학술대회논문집
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• 한국소성가공학회 2003년도 추계학술대회논문집
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• pp.201-206
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• 2003

Plastic injection mould have two kinds of trouble, one is in mould another in injection parts. Most of defects of the former take the cause in a design like in structure and working, the later weld line, transforming, sink mark, burning, flow mark, scratching, shading, black hole and so on. Most of problems of the later is difficult for making a clear definitely the reason of defects because of complexible. The purpose of this paper is to improve the quality of plastic injection mould and parts with inquiring the counter plan and rouble of the part of Flat TV Front Cover by flow control method and gas- assisted injection moulding. For minimizing defects from injection moulding parts, this paper was investigated with using computer aided injection mold filling simulations. Based on these numerical results, I established guidelines mould design and injection processing condition. As a results I got the improve of quality, minimizing surface defects moulded parts and troubles in mould.

• 소성∙가공
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• 제12권8호
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• pp.738-743
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• 2003

The major problems of a plastic injection mould can be devided into two kinds, one is in mould another in injected parts. Most of defects of the former comes from mould design, such as, structure and working. The latter are weld line, warpage, sink mark, burning, flow mark, scratching, shading, black hole and so on. Most of problems in injection molding are difficult to find the reason because of complexity. The purpose of this paper is to improve the quality of plastic injection mould and parts with inquiring the counter plan and analizing troubles of the part of Flat TV Front Cover by flow control method and gas-assisted injection moulding. For minimizing defects of the injection moulded parts, computer aided simulation method for injection mould filling was used. Based on these numerical results, the guidelines of mould design and injection processing condition were established. As a result, the improvement of quality, such as minimizing surface defects of injection moulding parts and troubles in mould was achieved.

• 품질경영학회지
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• 제38권2호
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• pp.190-201
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• 2010

This research proposes a method for designing VSI (Variable Sampling Interval) control charts with supplementary run rules. The basic idea is to apply various run rules and the VSI scheme to a control chart in order to increase the sensitivity. The sampling process of the VSI run rules chart is constructed by Markov chain approach. A procedure for designing the VSI run rules chart is proposed based on Lorenzen and Vance's model. Sensitivity study shows that the VSI run rules charts outperform the FSI (Fixed Sampling Interval) run rules charts for wide range of process mean shifts. A major advantage of the VSI run rules chart over other charts such as CUSUM, EWMA, and adaptive charts is it's simplicity in implementation. Some useful guidelines are proposed based on the sensitivity study.

• Molecules and Cells
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• 제45권5호
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• pp.284-290
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• 2022

Exosome, a type of nanoparticles also known as small extracellular vesicles are gaining attention as novel therapeutics for various diseases because of their ability to deliver genetic or bioactive molecules to recipient cells. Although many pharmaceutical companies are gradually developing exosome therapeutics, numerous hurdles remain regarding manufacture of clinical-grade exosomes for therapeutic use. In this mini-review, we will discuss the manufacturing challenges of therapeutic exosomes, including cell line development, upstream cell culture, and downstream purification process. In addition, developing proper formulations for exosome storage and, establishing good manufacturing practice facility for producing therapeutic exosomes remains as challenges for developing clinical-grade exosomes. However, owing to the lack of consensus regarding the guidelines for manufacturing therapeutic exosomes, close communication between regulators and companies is required for the successful development of exosome therapeutics. This review shares the challenges and perspectives regarding the manufacture and quality control of clinical grade exosomes.

• 한국건설관리학회논문집
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• 제13권4호
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• pp.3-15
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• 2012

현재 BIM을 도입한 주요 국가들은 BIM 발주 또는 납품 전 단계에서 설계사가 설계과정 중 기본적인 품질 확보가 가능하도록 필요한 지침을 제공하고 있다. 그러나 국내 건설산업의 경우, BIM의 도입 및 적용은 확산되고 있으나, BIM 발주 시 설계품질을 고려한 지침은 제공되지 않고 있다. 이로 인해 설계사는 자의적 해석에 의존적일 수밖에 없으며, 발주자는 납품받은 BIM 데이터의 품질을 신뢰하기 힘든 상황이다. 또한, BIM 소프트웨어의 내부 오류는 파악할 수 없는 관계로 자체 포맷에 의한 품질검토는 BIM 데이터의 품질을 확보하기 어렵다. 따라서 BIM 데이터의 품질을 높이기 위해서는 개방형 BIM(IFC)을 활용한 객체모델링과 객체별 속성 정의 등을 포함하는 지침을 개발할 필요가 있다. 이는 BIM 데이터의 기본 품질을 보증하고, 품질검토를 통하여 좀 더 나은 품질을 확보하는데 활용될 수 있다. 이에 본 연구는 설계품질 향상을 위한 개방형 BIM기반의 품질관리 방안으로 해외 주요 국가들의 선진사례와 품질검토 소프트웨어를 조사 분석하여 기본적인 품질관리가 가능한 요구조건을 제시하였고, 기존 BIM 사례에 적용하여 요구조건의 유용성을 검토하였다.

• 한국멀티미디어학회논문지
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• 제9권6호
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• pp.693-699
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• 2006

Object-oriented databases (OODBs) have been adopted for managing non-standard applications such as computer-aided design (CAD), office document management and many multimedia applications. One of the major characteristics of OODBs is class hierarchy where a subclass is allowed to inherit the definitions defined on its superclasses. In this paper, I present the evaluation metrics for class hierarchy quality in OODBs. These metrics are developed to determine if a concurrency control scheme can achieve good performance or not on a given class hierarchy. I first discuss the existing concurrency control schemes for OODBs. Then I provide evaluation metrics based on structural information and access frequency information in class hierarchies. In order to discuss significance of the proposed performance metrics, an analytical model is developed. Analysis results show that the performance metrics are important factor in concurrency control performance. I consider both single inheritance and multiple inheritance. The proposed metrics can be used to provide guidelines on how to design class hierarchy of an OODB for maximizing the performance of concurrency control technique.

• 한국의학물리학회지:의학물리
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• 제28권2호
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• pp.67-75
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• 2017

Prior to the introduction of a medical apparatus based on heavy-ion medical accelerator in Korea, a study is needed on quality control in clinical operation for the safe and appropriate usage of the instrument. Data relevant for the study were obtained via information sharing sessions and visits by the Particle Therapy Co-Operative Group (PTCOG) and other related academic associations. Furthermore, investigative analysis of the European and Japanese performance evaluation guidelines for heavy ion, as well as research on relevant literature, were conducted. In addition, instrumental standards were analyzed through an investigation of the current usage status of the heavy-ion medical accelerator, and further analysis was conducted on the evaluation methods for the performance, safety, and significance of the instrument. Based on these analyses, regular quality control procedures for heavy-ion medical accelerators in hospitals and other institutes were extrapolated. It is hoped that the results of this study will facilitate hospitals that have introduced heavy-ion medical accelerators, or are considering the implementation of the instrument, in their understanding of the fundamental standards and capabilities of the treatment system, as well as in establishing and carrying out quality control procedures for clinical operations such that it will contribute to the safety of patients and the efficiency of medical practitioners.

• International Journal of Stem Cells
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• 제17권2호
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• pp.147-157
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• 2024

The objective of standard guideline for utilization of human lung organoids is to provide the basic guidelines required for the manufacture, culture, and quality control of the lung organoids for use in non-clinical efficacy and inhalation toxicity assessments of the respiratory system. As a first step towards the utilization of human lung organoids, the current guideline provides basic, minimal standards that can promote development of alternative testing methods, and can be referenced not only for research, clinical, or commercial uses, but also by experts and researchers at regulatory institutions when assessing safety and efficacy.

• KIEAE Journal
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• 제17권1호
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• pp.55-61
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• 2017

Purpose : As the necessity of reinforcement of infections management in medical facilities after MERS increased, Ministry of Health and Welfare promulgated the enforcement regulations of medical law on February 3, 2017. Its main objective is to improve patients' safety and medical-care quality through the establishment of isolation facilities from infectious diseases and the set-up of standards for In-patient and ICU facilities. The purpose of this study is necessarily to propose a standardized spatial composition model for ward modules by analyzing changing environments of in-patient facilities according to the strengthened medical law. Method: Theoretical studies will be undergone of Evidence-based Designs to improve patients' safety, medical quality, and domestic/overseas in-patient room guidelines. With reference to the status of 24 general hospitals over 500 beds, the spatial compositions of the in-patient rooms and the types of multi/single bed room modules will be analyzed. The directions of future in-patient room module changes through the study of the minimum ward module types and various ward types will be presented. Result: This paper will hopefully provide guidelines for hospitalization rooms that can be applied to the revised rules of medical law enforcement and provide a basis for a comprehensive study of patients' safety and efficient infection control as well.

• 한국의료질향상학회지
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• 제30권1호
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• pp.153-164
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• 2024

The second National Patient Safety Comprehensive Plan was developed in 2023. In this, national-level patient safety education is designated as the fifth core task, with the establishment of an educational system for preliminary healthcare professionals included as a detailed task. The foundation for providing patient safety education to preliminary healthcare professionals has now been established. In 2011, the World Health Organization (WHO) published standard guidelines for patient safety education for healthcare professionals. This study introduces the WHO's 'Patient Safety Curriculum Guide: Multi-professional Edition' and shares the experiences and cases of patient safety education conducted for nursing students-that is, future nurses-according to these guidelines. The patient safety and nursing course was designed as an elective in the second semester of the third year. Before the class was conducted, only 6.9% of the students were familiar with the concept of patient safety. Of the 11 WHO topics, this course covers nine (excluding infection control and medicine safety) and is divided into seven modules. Three modules consist of lectures only, whereas the remaining modules involve practical training. To practice patient safety, it is essential for all healthcare professionals to acquire knowledge regarding patient safety during their undergraduate curriculum. This study aimed to provide foundational information regarding patient safety education for nursing and other healthcare students who have not yet undergone patient safety training.