• BMB Reports
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• 제50권4호
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• pp.160-161
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• 2017

Proper maintenance of biological components is crucial for longevity and healthy aging. Although the role of homeostatic maintenance systems for DNA and protein in longevity is established, it remains largely unknown for RNA. In our recent work, we show that nonsense-mediated mRNA decay (NMD) promotes longevity in the roundworm C. elegans by enhancing RNA quality control. We find that the activity of NMD decreases during aging, raising the possibility that RNA quality declines in old animals. We then show that key components of NMD complex are required for prolonged lifespan in C. elegans. In addition, animals with reduced insulin/insulin-like growth factor-1 (IGF-1) signaling (IIS), a representative longevity model, display increased NMD activity. Thus, up-regulation of NMD appears to play crucial roles in longevity conferred by reduced IIS via enhancing mRNA quality control. As both IIS and NMD pathways are evolutionarily conserved, mammals including humans may be equipped with similar RNA quality control systems to achieve longevity.

• 상하수도학회지
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• 제23권3호
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• pp.287-293
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• 2009

The study involved the measurement of flowrate and BOD in the Yeoju area and analyzed annual sewerage data by the I/I analysis technique which is common in Korea. The results of this study are as follows. The I/I for the Y-1 site before maintenance and after the completion of the whole process was reduced from 62% to 16.1% respectively with respect to maximum sewage flow per day. The average quality of water increased. The study measured the Y-2 site from a point of time corresponding to an 80% process rate and its I/I rate went up a little from 8.5% to 11.5%. At the Y-3 site, the I/I rate went up a little from 11% to 13.8%, while little change was noted in the average water quality. At the Y-4 site, the I/I rate was reduced from 43% to 16.9% and its average water quality went up. At the Y-5 site, the I/I quantity went up a little however its average water quality also went up largely. Therefore, it was concluded that the Y-5 site showed great improvement due to the sewer pipe maintenance.

• 융합정보논문지
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• 제11권3호
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• pp.125-131
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• 2021

모든 장비는 지속적인 사용에 의해 공정의 생산성과 경제성은 감소한다. 그러므로 일정 시점에서는 공정평균이동 문제라는 설비에 대한 예방보전이 필요하다. 설비의 보전시기를 결정함에 있어, 우리는 기존 연구에서 부분적으로 진행되어 온 보전모형들을 확장하고 통합함으로써 다양한 상황이 발생하는 생산 현장을 반영한 보전모형을 제시하고자 한다. 이를 구현하기 위해 제품규격은 상하한의 양쪽을 설정했으며, 적합품에 대해 품질손실함수를 도입했다. 마모수준에 대한 공정분산은 상수가 아닌 함수로 설정했으며, 특히 제품생산량과 보전비용에 있어서는 마모수준에 대한 함수를 개발하여 적용했다. 이로써 본 연구는 현장의 다양한 공정에 대부분 적용할 수 있는 보전모형이 될 것으로 생각한다. 추후 연구에서는 보전모형을 구성하는 부적합비용, 품질손실비용, 보전비용에 더하여 제품판매로 인한 수익 항목을 추가한 전체 수익 최대화 문제로 전개할 수 있을 것이며, 크게는 본 연구의 모형에 고장률을 도입한 보전모형으로의 확장도 생각해 볼 수 있을 것이다.

• 한국구조물진단유지관리공학회 논문집
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• 제5권4호
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• pp.155-160
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• 2001

KS-code(KS B 0896) for nondestructive ultrasonic testing classifies the quality level by relative flaw size only. But flaw position is more important than the flaw size. Test blocks having artificial holes near surface show lower yield load than the blocks having deeply located holes from the surface. So, level calibration table was proposed for classifying the quality level of welded steel structures.

• 플랜트 저널
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• 제11권2호
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• pp.45-51
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• 2015

손실비용을 고려하여 발전소 효율에 큰 영향을 미치는 복수기의 운전 관리 방안을 연구하였다. 2013년 S발전소의 해수온도는 복수기 압력과 뚜렷한 상관관계를 보였으며, 해수온도가 변화함에 따라 복수기 압력은 설계 압력 38.1 mmHg 보다 -1.7~+20 mmHg의 차이로 운전되었다. 제작사에서 제시한 열소비율 보정곡선을 통해 복수기 압력 1 mmHg 증가시 1,2호기 0.0201%, 3,4호기 0.0155%의 효율 손실과 1,2호기 12,830 원/h, 3,4호기 9,832 원/h의 시간당 손실비용이 발생함을 알 수 있었다. 또한 계절별 대응운전, 설비 노후화, 예방정비 시점에 따른 손실비용의 차이를 확인하고 월별 관리범위를 설정하였다. 이를 통해 운전 관리범위 준수, 손실비용을 고려한 정비 계획 수립으로 최소 2.5억원/년(1호기, 40일 정비)의 관리적 손실을 줄일 수 있을 것으로 판단된다.

• 한국도로학회논문집
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• 제10권2호
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• pp.115-124
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• 2008

본 연구에서는 단지 내 아파트 블록포장 50곳의 현장조사를 통하여 주요 파손형태를 조사하여 공용성을 평가하였다. 공용성 평가결과에 따르면, 조사대상지역에서 9년의 공용연수를 가진 블록포장의 유지관리지수는 7.9에서 8.9사이이며, 블록포장의 상태는 양호한 것으로 나타났다. 따라서 건설교통부 '보도설치 및 관리지침'에 10년으로 제시된 보도의 교체주기는 검토할 필요가 있다는 결론을 도출하였다. 또한 블록포장의 공용성을 객관적으로 평가하기 위해서 일본블록포장협회에서 제시한 유지관리 기준과 건설교통부 '보도설치 및 관리지침'의 유지관리기준을 조합하여 국내 현실에 적합한 유지관리기준을 제시하였다. 외국과 비고할 때 국내의 블록포장의 기준에는 내구성 관련기준과 줄눈채움재 및 모래안정층의 품질관리 기준이 명확히 제시되어 있지 않다. 따라서 블록포장의 기대수명과 유지관리비용을 줄이기 위하여, 본 연구에서는 국내외 기준을 비교하여 이러한 기준들을 국내기준에 포함시킬 것을 제안하였다.

• 산업기술연구
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• 제28권A호
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• pp.43-49
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• 2008

The track of high-speed railway get deteriorated according as using it. In that case, the maintenance jobs are needed for improvement of track quality. A scheduling problem for the track maintenance of high-speed railway is to determine the jobs should be performed daily. In the problem, the set of jobs for maintenance is given. Each job has it's parameters such as due date, emergency level, and processing time. In addition, jobs can be worked during a certain fixed time when the train doesn't move. In this study, we developed a mathematical model of the scheduling problem for the maintenance of high-speed railway and solved the problem using the ILOG CPLEX library.

• KIEAE Journal
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• 제10권4호
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• pp.29-37
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• 2010

The industrialized countries have promoted the rehabilitation of existing housing units as a national agenda, such as green policies, whereas korea, although having a housing stock as huge as that of world countries, have focused on the growth of housing by constructing new units rather than rehabilitating existing ones. Today, it has been so long since many multiple dwellings in Seoul and in the vicinity of Seoul were constructed. There were, however, very few political efforts to encourage the rehabilitation of housing. Today, substantial time has passed since multiple dwellings in Seoul and the first-stage new cities such as Bundang and Ilsan were constructed. What is required to maintain the quality of the existing housing and use it with safety is to promote the engineer of maintenance for multiple dwellings to work the maintenance of existing multiple dwellings. The objective of this study is to compare and analyze the maintenance qualification system of multiple dwellings of Japan, and then to propose to raise engineers of maintenance for multiple dwellings in korea.

• 아동학회지
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• 제31권1호
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• pp.163-177
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• 2010

The purpose of this study was to examine the maintenance of an evaluation accreditation indicator according to child care center teachers' participation in decision making. The subjects of this study were 139 teachers from 12 accredited national, public, private, and corporate child care centers in Seoul and North Gyeongsang Province. The TIP-2 (Teacher Involvement and Participation Scale V.2) and Accreditation Indicator for Child Care Centers were used to measure teachers' participation in decision making and accreditation indicator maintenance. Frequency, mean, standard deviation, one-way ANOVA and scheffe test were used for data analyses. The results revealed that the teachers who rated middle and high level in terms of their participation in decision-making showed higher levels of maintenance of the evaluation accreditation indicator than those with low levels of participation. This finding suggests that teachers' participation in decision making is an important factor for maintaining the quality of child care centers.

• 한국환경보건학회지
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• 제17권1호
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• pp.57-66
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• 1991

This study was carried out for 5 years between 1984 and 1986 and 1989 and 1990. This interviewers visited 292 households to evaluate the perception of the residents using .the. Simple Piped Water Supply (SPWS), and examined the pollution source surrounding 42 SPWS facilities and water quality by the chemical and microbiological method. The purpose of this study was to find out problems linked with SPWS and to investigate more efficient way of improvement in rural water supply. The results of the study are surmnarized as follows: 1) Approximately 55% of the sampled population have been served by simple piped water supply. 2) The drinking water was mostly taken from the springs in 16 sites and valley water in 26 sites. 3) Considering the type of distribution of the SPWS, there are 28 natural gravity systems and 14 pumping systems. 4) Out of the 180 SPWS in Chun Sung Area, 74% of the SPWS facilities were used more than ten years. In addition, 40% of residents expressed the need for repairs of old facilities. 5) 48% of the SPWS facilities are neighbored with pollution source. 6) 50% of the maintenance crews were not committed totheir job but instead, the facilities were operated by some residents or community leaders who were personally concerned about quality of the facilities. 7) About 85% of the residents answered that SPWS was convenient and helpful. 8) About 57% of the residents complaind that the amount of daily water supply is not adequate. 9) About 74% of the residents felt that the water quality is high for dringking water and therefore, 52% of the facilities were not properly chlorinated. But in contrast, the biochemical tests indicated that only 28% of the SPWS met the dringking water quality standards. 10) Maintenance cost per a household ranges form 500 to 2, 000Won (1 $ = 700 Won) a month. Most of the cost was to cover the power electric charge. For the effective maintenance and arrangement of the facilities, gorvermental financial support for the maintenance is strongly recommended.