• 제목/요약/키워드: Quality Assessment Tool

검색결과 509건 처리시간 0.024초

한국인 남성을 대상으로 한 햄스터 난자 침투 분석법의 정상 가임역 설정 (Establishment of Normal Fertile Range of Sperm Zona-free Hamster Ova Penetration Assay in Korean Male)

  • 김석현;방명걸;신창재;김정구;문신용;이진용;장윤석
    • Clinical and Experimental Reproductive Medicine
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    • 제18권1호
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    • pp.63-71
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    • 1991
  • To establish the normal fertile range in the results of the sperm zona-free hamster ova penetration assay (SPA) in Korean male, SPA using the low temperature ($4^{\circ}C$) capacitation in TEST-yolk buffer (TYB) was performed in 67 fertile and 26 infertile men. Sperm parameters in routine semen analysis were also checked and compared with the results of SPA. Sperm concentration, motility and motility index (MI) were significantly higher in fertile group compared with infertile group: $96.0{\pm}46.6$ vs $43.6{\pm}31.9{\times}10^6/ml$, $65.5{\pm}14.8%$ vs $45.8{\pm}23.6%$ and $46.31{\pm}13.29$ vs 27.40{\pm}17.98$, respectively. In fertile group, the hamster ova penetration rate (PR) was $98.5{\pm}5.0%$ (80%-100%), and the penetration index (mean penetrations per ovum, PI) was $9.59{\pm}6.35$(3.1-29.0). All the fertile men showed PI>3.0. In infertile group, PR was $24.6{\pm}24.8%$ (0%-70%), and PI was $0.40{\pm}0.42$ (0-1.3). Both PR and PI were significantly lower in infertile group. There was a significant correlation beween PI and sperm motility or MI, respectively, in fertile group whereas there was no correlation in infertile group. These data suggest that SPA using the low temperature capacitation in TYB can be a valuable diagnostic tool for the assessment of male fertility in vitro and provide an important supplement to the traditional tests of sperm quality.

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지표수-지하수 연계 기반의 통합수자원 관리를 위한 단위유역 제안 (A proposal of unit watershed for water management based on the interaction of surface water and groundwater)

  • 김규범;황찬익
    • 한국수자원학회논문집
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    • 제53권spc1호
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    • pp.755-764
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    • 2020
  • 현재 우리나라는 수자원단위지도의 표준유역(850개) 및 KRF의 집수구역(7,807개) 등의 기준 도면이 수자원 정책 수립의 기본 도면으로 활용되고 있으나, 물관리 일원화 시점에 맞추어 지표수-지하수의 연계 관리 및 수량-수질 통합관리를 위해서는 보다 적절한 규모의 표준 도면 설정이 필요해 보인다. 지표수에 비하여 지하수는 느린 이동 속도를 보이고 3차원 흐름 특성을 갖고 있으므로 지표수-지하수 연계 평가를 위해서는 광역적 규모의 유역 보다는 준 유역 규모가 보다 효과적인데, 표준유역보다 평균 면적이 작은 KRF 집수구역은 1차 또는 2차 지류를 포함하는 준 유역 규모에 해당한다. 그러나, KRF는 지표수 수계를 기준으로 구역을 구분하였기 때문에 넓은 평지 또는 높은 산악지역에서는 지나치게 작거나 큰 면적을 갖고 있다. 따라서, 지표수-지하수 연계 통합 관리에 적합한 단위 유역은 기존 KRF 집수구역을 수정하여 설정하는 것이 필요하다. 이로부터 설정될 개소 당 약 5 ~ 15 ㎢ 면적의 단위 유역은 지류의 구성과 관정의 위치를 고려할 때 지방자치단체의 수자원 관리의 기본 단위가 될 수 있으며, 물수요-공급 평가, 수문 계측 시스템의 배치, 지하수 허가 총량 기준, 오염의 평가, 정책의 우선 순위 결정 등 실질적인 수자원 통합관리의 기본 수단으로 활용 가능할 것이다.

수계 중 폴리브롬화 디페닐에테르 모니터링을 위한 Passive Sampling 적용 및 그랩 시료채취법의 대체 활용가능성 평가 (Application Assessment of Passive Sampling to Monitor Polybrominated Diphenyl Ethers in Water Environment as Alternative Sampling Method for Grab Sampling)

  • 김언정;서창동;임태효;오정은
    • 대한환경공학회지
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    • 제37권1호
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    • pp.45-51
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    • 2015
  • 폴리브롬화 디페닐에테르는 강한 소수성과 큰 분자량을 지닌 물질로 수체에 쉽게 용존되지 않으며, 이로 인해 다른 환경매체에 비해 수환경에 대한 연구는 많지 않다. 그러나 하 폐수처리장으로부터 수환경으로의 질량부하, 침적토에서의 재부유 현상 그리고 부유 입자 및 콜로이드로부터의 분배현상은 무시할 수 없는 영향을 미칠 것이다. 따라서 수환경 중 폴리브롬화 디페닐에테르를 조사하는 것은 중요하면서도 어려운 작업이다. 최근에 수환경에서 소수성물질을 모니터링 할 때의 어려움을 극복하기 위한 방안으로 반투과성막장비와 같은 수동적 시료채취 기법이 사용되고 있다. 수동적 시료채취를 사용하면 시료채취 기간 동안 주변환경인자의 변동을 조절하며 미량으로 존재하는 폴리브롬화 디페닐에테르를 검출하고 장기간에 거쳐 재현성 있는 모니터링 결과를 얻을 수 있다. 따라서 본 연구에서는 반투과성막장비(SPMD)를 수질 모니터링 장비로서 활용하는 가능성을 확인하고자 하였다. 강둑에서 그랩, 혼합 시료채취법과 SPMD를 적용하여 다양한 수질시료 채취기법에 따른 시간적 변동과 농도 차이를 확인하고 SPMD를 사용하여 폴리브롬화 디페닐에테르의 수환경 중 농도를 예측할 수 있는지 평가하였다.

ADS-33 평가기준에 따른 소방헬기 비행시뮬레이터의 비행조종성 예비평가 (Preliminary Evaluation of Handling Qualities of a SAR(Search & Rescue) Helicopter Simulator Based on ADS-33 Requirements)

  • 윤석준;김동현;성은혜;박태준;황호연;안존;이정훈
    • 한국항공우주학회지
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    • 제44권9호
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    • pp.796-805
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    • 2016
  • 본 연구는 헬리콥터 비행 시뮬레이터 개발의 첫 번째 단계의 일환으로 비행 운동 모델의 비행조종성을 해석적으로 평가한다. 비행 운동 모델은 시뮬레이터의 목표 항공기인 AS365 N2의 공개 정보를 사용하여 생성하였다. 해당 비행 시뮬레이터는 소방 임무에 대한 조종사 교육 및 연구 도구로 개발 중이다. 모델의 평가는 비행 시험 데이터를 통한 검증이 이루어지기 전에 모델의 비행 특성과 다음 개발 단계로의 적합성을 평가하기 위하여 수행된다. 평가는 항공기분류, 임무 및 환경을 고려하여 ADS-33E-PRF(Aeroautical Design Standard Performance Specification Handling Qualities Requirement)의 기준에 의거하여 수행한다. 항공기의 해석적 비행은 규정에 대한 적합성 평가를 위해 요구되는 혹은 권장되는 비행시험절차를 따른다. 평가 결과는 ADS-33E-PRF에 명시된 조종성 등급에 따라 평가되는데 RotorLibFDM을 기반으로 생성된 비행 운동 모델이 헬기 비행에 대한 기본 교육과 연구로 사용될 수 있는 일반적인 헬리콥터 시뮬레이터에 대한 만족스러운 플랫폼을 제공함이 확인되었다.

Water and mass balance analysis for hydrological model development in paddy fields

  • Tasuku, KATO;Satoko, OMINO;Ryota, TSUCHIYA;Satomi, TABATA
    • 한국수자원학회:학술대회논문집
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    • 한국수자원학회 2015년도 학술발표회
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    • pp.238-238
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    • 2015
  • There are demands for water environmental analysis of discharge processes in paddy fields, however, it is not fully understood in nutrients discharge process for watershed modeling. As hydrological processes both surface and ground water and agricultural water managements are so complex in paddy fields, the development of lowland paddy fields watershed model is more difficult than upland watershed model. In this research, the improvement of SWAT (Soil and Water Assessment Tool) model for a paddy watershed was conducted. First, modification of surface inundated process was developed in improved pot hole option. Those modification was evaluated by monitoring data. Second, the monitoring data in river and drainage channel in lowland paddy fields from 2012 to 2014 were analyzed to understand discharge characteristics. As a case study, Imbanuma basin, Japan, was chosen as typical land and water use in Asian countries. In this basin, lowland paddy fields are irrigated from river water using small pumps that were located in distribution within the watershed. Daily hydrological fluctuation was too complex to estimate. Then, to understand surface and ground water discharge characteristics in irrigation (Apr-Aug) and non-irrigation (Sep-Mar) period, the water and material balance analysis was conducted. The analysis was composed two parts, watershed and river channel blocks. As results of model simulation, output was satisfactory in NSE, but uncertainty was large. It would be coming from discharge process in return water. The river water and ground water in paddy fields were exchanged each other in 5.7% and 10.8% to river discharge in irrigation and non-irrigation periods, respectively. Through this exchange, nutrient loads were exchanged between river and paddy fields components. It suggested that discharge from paddy fields was not only responded to rainfall but dynamically related with river water table. In general, hydrological models is assumed that a discharge process is one way from watershed to river. However, in lowland paddy fields, discharge process is dynamically changed. This function of paddy fields showed that flood was mitigated and temporally held as storage in ground water. Then, it showed that water quality was changed in mitigated function in the water exchange process in lowland paddy fields. In future, it was expected that hydrological models for lowland paddy fields would be developed with this mitigation function.

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AvSWAT를 이용한 농촌유역 비점원 오염물질 부하량 예측 (Estimation of Nonpoint Source Pollutant Loads for Rural Watershed by AvSWAT)

  • 김진호;이종식;김원일;정구복;한국헌;류종수;김석철;윤순강;이정택;권순국
    • 한국토양비료학회지
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    • 제40권1호
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    • pp.12-17
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    • 2007
  • 유역관리모형은 유역내 비점원 오염부하를 예측하고, 서로 다른 오염원과 토지이용형태에 따른 영향을 판단하는데 사용 되어진다. 많은 모형들이 비점원오염의 예측이 가능하지만, 각기 서로 다른 한계를 갖고 있다. 모델의 선택의 연구목적과 축적된 가용자료에 부합해야 한다. 최근 한국에서는 SWAT모형이 농촌유역의 비점원오염 유출을 예측하기 위해서, 많이 이용되고 있다. 대부분의 자료들이 GIS를 이용하여 자동적으로 생성되지만, 일부 자료들은 농민들과 연구자들을 통해 직접 수집해야 한다. AvSWAT모형에 의해 시뮬레이션된 유량과 관측유출은 매우 좋은 결과를 나타내었다. 그러나 유출은 경향은 주로 강우와 물부족기간에 의해 그 경향을 따라간다. AvSWAT 모형을 농촌유역에 적용하여 유출을 평가한 결과 모델치는 1023.3 mm이고, 관측치는 967.4 mm인 것으로 나타났다. 또한 수질의 경우 모델치와 관측치의 결정계수는 인이 질소보다 더 높은 값(0.79)을 보여주고 있었다.

뇌졸중 환자의 지역사회이동을 위한 작업치료 중재: 체계적 고찰 (Occupational Therapy for Community Mobility in Stroke Patients : Systematic review)

  • 조은주;감경윤;장문영
    • 대한지역사회작업치료학회지
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    • 제8권3호
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    • pp.77-89
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    • 2018
  • 목적 : 본 연구는 뇌졸중 환자에게 적용한 지역사회이동을 위한 작업치료적 중재를 분석한 논문으로, 임상에서 지역사회이동에 대한 중재를 사용하는데 있어 근거를 제시하고자 한다. 연구방법 : PRISMA checklist와 diagram을 통해 체계적 고찰을 시행하였고, 데이터베이스는 PubMed, EMBASE, Cochrane library (CENTRAL), ProQuest Dissertations & thesis (PQDT), 한국교육학술정보원(RISS)과 코리아메드(KoreaMed)를 이용하였다. 검색기간은 2005년부터 2018년 9월까지로 하였다. 연구에 선택된 문헌의 질 평가는 RoBANS (Riks of Bias Assessment tool for Non-randomized Study)를 사용하였다. 연구에 포함된 문헌은 총 8개이었다. 문헌에서 사용된 중재들은 종류에 따라 분류하였다. 결과 : 문헌의 연구디자인은 무작위배정 실험연구, 유사실험연구, 전후비교연구, 환자-대조군연구, 횡단적 연구로 다양하게 나타났다. 포함된 문헌의 질적수준은 level I이 1편(12.5%), level II가 6편(75%), level III가 1편(12.5%)으로 나타났다. 문헌의 '편향 위험 낮음' 비율은 62.5%~87.5%로 각 문헌마다 다르게 나타났다. 문헌에 사용된 중재는 가상 현실 및 가상환경을 기반으로 한 중재가 4편(50%)으로 가장 많았고, 프로토콜을 이용한 중재가 3편(37.5%), 휠체어 사용훈련이 1편(12.5%)으로 나타났다. 각 중재의 효과는 전반적으로 유의미하게 나타났다. 결론 : 본 연구는 지역사회이동에 대한 작업치료의 중재효과를 체계적으로 보고하여 임상적 적용근거를 제공하였다. 추후 지역사회이동성에 대해 다양한 형태로 중재를 적용한 연구가 이루어져야 할 것이다.

류마티스 관절염 치료제와 병용한 독활기생탕의 효과 및 안전성: 체계적 문헌고찰 및 메타분석 프로토콜 (The Effectiveness and Safety of Dokwhalkisaeng-tang Combined with the Medication on Rheumatoid Arthritis: A Study Protocol for Systematic Review and Meta-analysis)

  • 채수연;정찬영;김주희;김은정;서병관;황민섭;박성식;김경호;윤종화;성원석
    • 대한한의학방제학회지
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    • 제30권2호
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    • pp.95-100
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    • 2022
  • Objectives : Recent studies reported that Dokwhalkisaeng-tang (DHJST) could relieve the clinical rheumatoid arthritis (RA) symptoms and the level of RA-related blood test. However, evidence-based review on effectiveness and safety of DHJST with medication on RA was not yet provided. Methods : Searching randomized controlled trials on the use of DHJST for RA will be performed using multiple electronic databases, manual search, and contact to author. Studies will be selected according to the pre-defined criteria and collected data on study participants, interventions, control groups, outcome measurements, the results, adverse events, and risk of bias will be summarized. Primary outcome will be the disease activity score (including effective rate, swollen joint count, tender joint count, and morning stiffness), and the secondary outcomes will be RA-related blood test and adverse events. We will use Review Manager software to perform a meta-analysis, Cochrane Collaboration "risk of bias" tool for assessing the risk of bias, and Grades of Recommendation, Assessment, Development and Evaluation for the determination of quality of evidence. Results : We are going to investigate the effectiveness and safety of DHJST with medication for RA. Conclusion : This study will provide reliable evidence on whether DHJST combined with medicine is more effective on RA than medicine monotherapy.

한랭 두드러기에 대한 한약 치료: 체계적 문헌 고찰 및 메타분석 (Herbal Medicine Treatment for Cold Urticaria: A Systematic Review and Meta-Analysis)

  • 김혜나;오정화;윤화정
    • 한방안이비인후피부과학회지
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    • 제36권4호
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    • pp.122-144
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    • 2023
  • Objectives : The purpose of this study is to evaluate the effects of herbal medicine treatment in patients with cold urticaria. Methods : We searched randomized controlled trials(RCTs) reporting the effects of herbal medicine for cold urticaria through domestic and international databases from their inception to September 2023. The results were summarized in tables. We assessed the risk of bias in included RCTs through Cochrane risk of bias tool and the data synthesis was conducted through RevMan version 5.4. Results : A total of 12 RCTs were included in this review and all trials compared herbal medicine alone treatment(treatment group) with western medicine alone treatment(control group). The total effective rate(TER) of treatment group was statistically higher than that of control group(RR: 1.49, 95% CI: 1.38 to 1.62, p<0.00001, I2=65%). On the other hand, when comparing except for 1 trial with different evaluation period, the TER of treatment group was statistically higher than that of control group and heterogeneity was very low(RR: 1.36, 95% CI: 1.26 to 1.47, p<0.00001, I2=0%). And when comparing 8 trials using the total symptom score(TSS) change index as an indicator of TER, the TER of treatment group was statistically higher than that of control group and heterogeneity was very low(RR: 1.38, 95% CI: 1.26 to 1.51, p<0.00001, I2=0%). The treatment group showed more statistically significant decrease compared to the control group in TSS(MD: -2.51, 95% CI: -2.63 to -2.40, p<0.00001, I2=99%). The relapse rate of treatment group was statistically lower than that of control group(RR: 0.19, 95% CI: 0.10 to 0.40, p<0.00001, I2=0%). Mild adverse events such as sleepiness, dizziness were reported in control group and gastric discomfort was reported in treatment group. In the risk of bias assessment, many cases were evaluated as 'Unclear risk'. Conclusions : This review found that herbal medicine alone treatment could more effective and safe than western medicine alone treatment for cold urticaria. But further well-designed researches are needed because of heterogeneity between trials and the quality of the included trials.

퇴원환자의 가정간호요구와 가정간호사업의 효과 분석 - 일 종합병원을 중심으로 (A Study of Home Care Needs of Patients at Discharge and Effects of Home Care -Centered on Patients Discharged from a Rural General Hospilal-)

  • 최연순;김대현;서미혜;김조자;강규숙
    • 대한간호
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    • 제31권4호
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    • pp.77-99
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    • 1992
  • The study was carried out at W. hospital, an affiliated hospital of Y university, involved a total of 163 patients who were discharged from the hospital between May 1990 und March 199J. Data collection was twice, just prior to discharge and a minimum of three months post discharge. Thirty patients who lived within a hour travel time of the hospital received home care during the three months post discharge. Nursing diagnoses and nursing interventions For these patients were analyzed in this study. The results of the study are summarized as follows : 1. Discharge needs for the subjects of the study were analyzed using Gordon's eleven Functional categories and it was found that 48.3% of the total sample had identified nursing needs. Of these, the needs most frequently identified were in the categories of sexuality, 79.3 %, health perception, 68.2 % self concept, 62.5 %, and sleep and rest 62.5 %. Looking ut j he nursing diagnosis that were made for the 30 patients receiving home care, the following diagnoses were the most frequently given; alteration in sexual pattern 79.3%, alterations in health maintenance, 72.6%, alteration in comfort, 68.0%, depression, 64.0%, noncompliance with diet therapy, 6.3.7%, alteration in self concept, 55.6%, and alteration in sleep pattern, 53%. 2. In looking at the effects of home nursing care as demonstrated by changes in the functional categories over the three month period, it was Found that of the 11 functional categories, the need level for health perception, nutrition, activity and self concept decreased slightly over the three month period. On the average sleep patterns improved, but restfulness was slightly less and bowel elimination patterns improved but satisfaction with urinary elimination was slightly less. On the other hand, role enactment, sexuality, stress management and spirituality decreased slightly. The only results that were statistically significant at the 0.05 level were improvement. in digestion and decrease in pain. No statistically significant changes were found in ability related to ADL, the total ADL Score at discharge was $19.78{\pm}8.234, and after 3 months $19.01{\pm}8.12$. Considering that a majority of the patients were over 60 years of age and that many had brain or spinal cord injuries, the fact that their ADL ability did nor deteriorate after discharge can be interpreted as related to a positive impact by the home health care nurses. Similarly there was a slight be not statistically significant decrease in the quality of life scores between the two lest times(l47.83 at discharge and 113.02 at the three month period). Again, when the chronic nature of thee problems facing these patients is considered this maintenance of quality of life can be interpreted as a positive impact by the home health care nurses. 3. One of the home care nursing activities was diagnosis. For this activity it was found that for nine functional health categories(sexuality and spirituality excepted) there were 20 nursing diagnoses. The most frequent were noncompliance, alteration in skin integrity both actual and potential, and impaired physical mobility in that order. 4. Delivery of home health care by the home health nurses included the following nursing activities; assessment, patient education, demonstration of care activities, counselling, direct care to the patient and referrals. Direct care included changing dressings, bladder irrigations, changing Foley catheters, measurement of residual urine, perineal care, position change, back care, oral hygiene, exercise and massage of motion exercises, cleansing enemas, tracheostomy suctioning and tracheostomy care, care of dentures, applications of heat and other similar nursing activities. In conclusion almost 50% of (he sample indicated a need for continued nursing care at the time of discharge and for the patients in the sample who received home care there was a slight decrease in nursing needs but while the patients had chronic and debilitation problems there was ill decrease in ADL abilities or in quality of life. Further study needs Lo be done La increase the reliability and validity of the tool that was used to measure home health care needs. It is also recommended that study by done using a randomized sampling with a control group to compare patients who receive home care with those who do not.

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