• Journal of Ginseng Research
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• 제37권1호
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• pp.124-134
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• 2013

The authentication of the physico-chemical properties of ginsenosides reference materials as well as qualitative and quantitative batch analytical data based on validated analytical procedures is a prerequisite for certifying good manufacturing practice (GMP). Ginsenoside Rb1 and Rg1, representing protopanaxadiol and protopanaxatriol ginsenosides, respectively, are accepted as marker substances in quality control standards worldwide. However, the current analytical methods for these two compounds recommended by Korean, Chinese, European, and Japanese pharmacopoeia do not apply to red ginseng preparations, particularly the extract, because of the relatively low content of the two agents in red ginseng compared to white ginseng. In manufacturing fresh ginseng into red ginseng products, ginseng roots are exposed to a high temperature for many hours, and the naturally occurring ginsenoside Rb1 and Rg1 are converted to artifact ginsenosides such as Rg3, Rg5, Rh1, and Rh2 during the heating process. The analysis of ginsenosides in commercially available ginseng products in Korea led us to propose the inclusion of the (20S)- and (20R)-ginsenoside Rg3, including ginsenoside Rb1 and Rg1, as additional reference materials for ginseng preparations. (20S)- and (20R)-ginsenoside Rg3 were isolated by Diaion HP-20 adsorption chromatography, silica gel flash chromatography, recrystallization, and preparative HPLC. HPLC fractions corresponding to those two ginsenosides were recrystallized in appropriate solvents for the analysis of physico-chemical properties. Documentation of those isolated ginsenosides was achieved according to the method proposed by Gaedcke and Steinhoff. The ginsenosides were subjected to analyses of their general characteristics, identification, purity, content quantification, and mass balance tests. The isolated ginsenosides showed 100% purity when determined by the three HPLC systems. Also, the water content was found to be 0.534% for (20S)-Rg3 and 0.920% for (20R)-Rg3, meaning that the net mass balances for (20S)-Rg3 and (20R)-Rg3 were 99.466% and 99.080%, respectively. From these results, we could assess and propose a full spectrum of physico-chemical properties of (20S)- and (20R)-ginsenoside Rg3 as standard reference materials for GMP-based quality control.

• 대한간호학회지
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• 제28권3호
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• pp.773-785
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• 1998

This study aims at providing more qualitative care in family nursing practice. It is designed to analyze the degree of quality of life(QL) among families of the patients. The subjects consisted of 79 families of hospital hospice patients and 74 families of home-based hospice patients. The ages of the subjects were 17-74 years, at five university hospitals in Seoul, Inchon, and Kyung Gi Province, and one clinic in Chunchon. The data were collected from September, 1996 to August, 1997. The instrument used for the study was the Quality of Life Scale (QLS), which was composed of six factors, developed by Ro, You Ja. The analysis was done using t-test, ANOVA Scheff test, and Stepwise multiple regression. The results were as follows : 1. There were no statistically significant differences between the families of hospital hospice patients and the families of home-based hospice patients ; however, the mean score of the families of hospital hospice patients was higher than that of the families of home-based hospice patients. The scores on QLS ranged from 75 to 224 with a mean score of 140.58 in the families of hospital hospice patients. In the families of home-based hospice patients, the scores ranged from 79 to 214, showing a mean score of 135.25. Among six factors of QLS, family relationships showed the highest score in both groups, but economic life showed the lowest score in the families of hospital hospice patients, and emotional state showed the lowest score in those of home-based hospital patients. Self-esteem and relationship with the neighborhood were significantly higher in the families of hospital hospice patients than the families of home-based hospice patients (t=2.69, P= 0.008 ; 1=2.04, p=0.043). 2. In the families of hospital hospice patients, QL had significant relationship with family member's age(F=2.52, p =0.029), marital status (F=3.57, P=0.018), economic state(F=6.07, P=0.004), and education level(F=3.77, P=0.014). In the families of home-based hospice patients, QL had significant relationship with marital status (F=2.53, P=0.049), education level(F=4.35, P=0.007), occupation(F=3.93, P=0.002), and patient's age(F=2.73, P=0.020) 3. Economic status accounted for 17% of QL, and diagnosis accounted for an additional 7% of QL in the families of hospital hospice patients by means of stepwise multiple regression analysis. In the families of home-based hospice patients, relationships with patient accounted for 12% of QL. The findings showed that self-esteem and relationship with the neighborhood were significantly higher in the families of hospital hospice patients than the families of homed-based hospice patients and family relationships showed the highest value in QL. These findings should be considered in nursing practice.

• 정보교육학회논문지
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• 제20권2호
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• pp.139-150
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• 2016

스마트디바이스의 기술적 발전은 학교 교육체제의 변화를 이끄는 동인이다. 스마트교육이 학교 내 안착하려면 최종 수용자 집단인 다수 일반교사들이 스마트교육에 대해 어떻게 인식하고 있으며, 그들의 실제 활용은 어느 정도인지에 대해 규명할 필요가 있다. 이 연구는 일반교사들이 인식하는 스마트교육의 특성을 질적 연구 방법으로 도출한 후, 학교현장에서 스마트교육의 활용에 대한 중요도와 수행도 차이를 양적 연구 방법으로 분석하여 일반교사가 체감하는 스마트교육의 실태를 규명하고자 수행되었다. 스마트교육 속성에 대한 일반교사의 인식을 규명하기 위해 선행연구를 분석하였고, 8명의 일반교사를 대상으로 수업 관찰 및 반구조화된 질문지를 이용한 심층면담 등 질적 연구방법을 실시하였고, 스마트교육에 대한 그들의 1차 핵심 개념 72개를 선정하였다. 그 후 연구자간 논의를 거쳐 16개의 최종 개념, 6개의 하위 범주, 3개의 상위 범주를 도출하였다. 16개 개념을 토대로 일반교사들의 스마트교육 속성에 대한 중요도-실행도를 분석(IPA)하였으며, 스마트교육에 대한 일반교사들의 중요성 인식과 활용 수준에 대한 도출 결과를 토대로 진일보한 스마트교육 실천을 위한 시사점을 제시하였다.

• 한국조경학회지
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• 제31권5호
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• pp.20-30
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• 2003

This study is aimed at establishing the categories and items for ecological assessment and evaluation of the environmental friendliness of golf courses in the capital region of Korea. The categories and items for the assessment have been derived based on the existing literature and interviews with golf experts. This study covers 32 golf courses in the capital region of Korea that are available in terms of data and on-site surveys. In order to conduct a comprehensive assessment of the environmental friendliness of the golf courses, the assessment area was divided into 4 categories that include a total of 14 sub-categories. The 4 categories encompass 1) location, 2) topography, 3) vegetation, and 4) construction. As its sub-categories, the location category includes current land use and zoning in the National Land Use Management Law. Topography has 2 sub-categories in the damage ratio of existing topography, gradient, cut area, and slope height. The assessment of vegetation is largely based on site surveys in the categories of preservation of the existing vegetation, the use of natural resources and existing trees, the component ratio of native tree species, the multi-layered structure of vegetation, and the utilization of water purification plants. In the aspect of construction, afforestation on tile slopes and the utilization of existing surface soil were evaluated. The examination of comparative analysis among the 10 items as a ratio measure showed that the scores were low in the sub-categories of current land we, the use of existing trees, and the multi-layered structure of vegetation. However, the rating results were satisfactory in the 2 sub-categories including cut area, and the utilization of native tree species. Those proved to be contributing factors in the ecological health of the golf courses. According to correlation analysis of the 10 items to the overall ecological rating of each golf course, the sizes of the 32 golf courses were mainly affected by the damage ratio of existing topography, gradient, preservation of vegetation and slope height. This study has the initiative to conduct an ecological assessment of golf courses in the country based on site surveys. The study results revealed that location factors such as current land use, damage ratio of topography and gradient and topographical factors were the main factors affecting the environmental friendliness of golf courses. This indicates indicating the significance of these factors in the future construction practices of golf courses. Furthermore, this study raises the need for follow-up studies to establish more detailed assessment criteria and to develop assessment techniques for areas such as slope afforestation and water purification plants that need a qualitative approach.

• 한국간호교육학회지
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• 제18권2호
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• pp.332-344
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• 2012

Purpose: The purpose of this study was to identify the current status of Asian research and suggest a direction for the future development of nursing research in Asian countries Methods: To examine the current status of Asian nursing research, 539 abstracts presented at the 2011 East Asian Forum of Nursing Scholars in Seoul were analyzed according to the structured analysis format. Results: The results showed that most of the studies (77.6%) were quantitative design, but qualitative design was also conducted. Most of quantitative studies were quasi experimental designs and questionnaires are most frequently used for data collection. Only 8.5% of the studies used physiological measures. Key words were categorized into four nursing metaparadigms: clients, environment, health and nursing. The most frequently mentioned domain was health. Main themes of research were elderly, chronic disease, health promotion, and nurse/nursing management. Most frequently used key words were elderly, social support, depression, and stress. Conclusion: Major trends were similar in Asian countries, and mostly conducted with quantitative designs. Research topics were varied and major interests in nursing research topics were elderly, health promotion, and mental health in all countries. We need to develop nursing science based on closer communication and cooperation among Asian countries.

• Asian Pacific Journal of Cancer Prevention
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• 제16권17호
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• pp.7789-7794
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• 2015

Background: This study aimed to evaluate the impact of a community-based health education and communication programme on reducing liver fluke infections caused by the consumption of uncooked fish among people in a high-risk area of Thailand. Materials and Methods: The study was quasi-experimental in nature, with three-stages. Stage 1 involved a situational and capacity analysis of designated communities in Khon Kaen province. This was followed by the development of a model for community-based health education and communication to prevent liver fluke infections among high-risk people, and, lastly, implementation and evaluation of the model were performed. Data were collected using both qualitative and quantitative methods. In total, 390 people were surveyed, and quasi-experimental and comparison groups, each with 90 people, were assessed between May 2011 and April 2012. Analysis was using statistical OR, 95 % CI, the Willcoxon matched pairs signed ranks test, the chi-square test, and the Mann-Whitney U test. Results: The findings showed that most respondents had a high level of knowledge and understanding of liver fluke disease (89.5%, 95% CI:86.0-92.4), and positive attitudes toward the prevention of the disease (94.4%, 95% CI:91.6-96.4). However, with regard to changes in consumption of uncooked fish, most respondents were still in the pre-contemplation phase (55.1%, 95% CI:50.0-60.1), followed by the contemplation phase, 22.6%. Furthermore, four factors were found to be associated with the consumption of uncooked fish - the consumption of alcohol (OR 4.16, 95% CI:1.79-9.65), gender (OR 3.17, 95% CI:1.53-6.54), smoking (OR 3.03, 95% CI:1.31-7.05), and age 40 years and above (OR 2.68, 95% CI:1.02-7.05). After nine months of the health education and communication programme using local media based on local wisdom, culture and persons, the results showed that, compared to the control group, members of the experimental group had a higher level of knowledge, a better attitude and lower levels of ill-advised consumption behaviour. Also, it was found that consumption of uncooked fish, by an assessment of the level of stage of change, was reduced. (p-value 0.002). Conclusions: The health education and communication programme developed as part of the study was effective in changing the consumption of uncooked fish. Therefore, this approach should be promoted in other high-risk areas in Thailand in the future.

• Journal of Hospice and Palliative Care
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• 제20권2호
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• pp.100-110
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• 2017

목적: 본 연구는 우리나라 사람들이 인지하고 있는 존엄한 죽음의 의미를 참여자의 관점에서 있는 그대로 탐구하여 확인하고 기술함으로써 그 구조와 본질을 규명하기 위한 것이다. 방법: 현상학적 분석방법을 적용한 질적 연구로 본 연구의 참여자들은 연령대와 성별을 고려한 일반인으로 총 13명이었다. 자료수집은 참여자와 개별적 심층면담을 통해 이루어졌으며, 자료분석은 Colaizzi(1978)의 현상학적 분석방법을 이용하였다. 결과: 우리나라 사람들이 인지하는 존엄한 죽음은 4개의 범주와 9개의 주제모음 및 18개의 주제로 구조화할 수 있었다. 4개의 범주는 '편안한 죽음', '보기 좋은 죽음', '해결하고 죽는 죽음', '남긴 죽음'이었고, 9개의 주제모음은 '고통 없는 죽음', '자연에 순응하는 죽음', '흉하지 않은 죽음', '좋은 회상을 남기는 죽음', '원하는 방식으로 죽는 죽음', '주변을 정리한 죽음', '응어리를 풀고 가는 죽음', '잘 살고 죽는 죽음', '인정받는 죽음'이었다. 결론: 우리나라 사람들이 의미하는 존엄한 죽음은 고통 없이 편안하게 죽으면서 다른 사람에게 피해를 주지 않고 남아 있는 삶 동안 모든 일을 해결하고 가족을 포함한 다른 사람과의 관계 속에서 좋은 이미지로 남아야 하는 것으로 나타나 우리나라 사람들의 존엄한 죽음을 위하여 임종을 앞둔 대상자의 호스피스 간호에 적용할 수 있을 것이다.

• 한국지능시스템학회논문지
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• 제26권5호
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• pp.416-422
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• 2016

수많은 플라스틱이 산업분야에 다양하게 사용되어지고 있다. 또한 많은 양의 플라스틱 폐기물들이 발생하고 있다. 재활용에 대한 연구는 환경오염 뿐만아니라 한정된 유용한 자원이 버려지는 것을 방지하기 위해 중요한 이슈로 부각되고 있다. 이렇기 때문에 폐플라스틱의 재활용은 재사용 관점에서 주목받고 있는 실정이다. 현재 재활용 센터에서는 플라스틱의 재질을 분류하기 위해 NIR 센서를 이용한 플라스틱 자동 분류 시스템을 구축 및 운용하고 있다. 하지만 흑색 플라스틱은 여전히 분류가 되지 않는 도전적인 목표로 남아있다. 카본 블랙이 포함된 흑색 플라스틱의 경우 검정색의 특성상 NIR 장비에서 나오는 빛을 흡수하기 때문에 분류에 어려움이 있다. 본 연구는 NIR 장비 대신 흑색 플라스틱을 분류하는 방법에 대한 연구이다. 흑색 플라스틱의 정성적, 정량적 분석을 위해 Raman 분광법을 사용하였다. 또한 분류기의 인식률을 높이기 위해 데이터를 특성을 분석하고 흑색 플라스틱을 좀 더 확실하게 분류하기 위해 Support Vector Machine(SVM), 주성분 분석법(PCA) 같은 알고리즘을 이용하였다.

• 한국산학기술학회논문지
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• 제20권12호
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• pp.493-501
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• 2019

본 연구의 목적은 부모의 돌봄참여에 대한 소아중환자실 간호사의 인식을 파악하는 것이다. 연구대상은 서울에 위치한 상급종합병원 2곳의 소아중환자실에 근무하고 있는 간호사 5명이며, 일대일 심층 면담을 수행하였다. 자료수집 기간은 2016년 1월부터 2월까지였고 전통적 내용분석을 이용해 자료를 분석하였다. 연구 결과 소아중환자실 부모의 돌봄참여에 대한 간호사의 인식은 5개 범주와 43개 하위범주가 도출되었으며, 5개 범주는 필요성, 의미, 효과, 장애 요인과 촉진방안으로 나타났다. 간호사는 소아중환자실에서 집중 간호를 필요로 하는 자녀의 중증 상태로 인해 부모가 정서적 부담을 경험하며, 면회가 제한된 병원 정책이 이러한 부담을 악화시킨다는 점에서 소아중환자실에서 부모 돌봄참여의 필요성과 그 효과를 인식하고 있었다. 주요한 장애 요인은 부모의 돌봄참여에 대한 간호사의 지식과 역량의 부족, 과중한 업무 부담, 소아중환자실과 병원 내 정책이나 지침의 부족으로 나타났다. 촉진방안은 간호사 대상 부모 돌봄참여의 의미와 실천방안에 대한 교육 제공, 간호사뿐 아니라 부모를 포함하여 인식개선 활동, 전담 전문가를 지원하는 방안으로 나타났다. 본 연구의 결과를 기반으로 향후 소아중환자실에서 부모의 돌봄참여를 통합적으로 도입하기 위한 간호 중재의 개발과 효과 검증을 위한 후속 연구가 필요할 것이다.

• 대한두경부종양학회지
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• 제34권1호
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• pp.21-27
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• 2018

Background/Objectives: This study aimed to evaluate the changes of uptake around the sternoclavicular joint (SCJ) according to 18F-FDG PET images in patients with head and neck cancer who underwent neck dissection. Materials & Methods: Retrospectively, the medical records of patients who received selective or comprehensive neck dissection were reviewed. Preoperative and 1-year postoperative 18F-FDG PET images, if available, were analyzed by nuclear medicine physicians in both qualitative and quantitative manners. Correlation between the changes of uptake around SCJ and perioperative data were statistically analyzed. Results: Thirty-seven patients satisfying the inclusion criteria were enrolled. Seven patients with increased uptake around SCJ on 1-year postoperative 18F-FDG PET showed a correlation with radical or comprehensive neck dissection, accessory nerve sacrifice, and high postoperative SUVmax. When 20 patients with increased uptake around SCJ according to quantitative measurement were compared with other patients without increased uptake, no parameter was significantly different, except postoperative SUVmax. Bivariate logistic regression analysis revealed that the clinical symptom (shoulder or sternal pain) was significantly correlated with the extent of neck dissection (OR 0.227, CI 0.053-0.966, p=0.045) and spinal accessory nerve sacrifice (OR 13.500, CI 1.189-153.331, p=0.036). Conclusions: Increased uptake around SCJ on 1-year postoperative 18 F-FDG PET was correlated with either the radical or comprehensive procedure, as well as with accessory nerve sacrifice. This suggests that subjective analysis of 18F-FDG PET can be used to detect subclinical shoulder instability.