• Structural Engineering and Mechanics
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• 제53권3호
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• pp.481-495
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• 2015

Many hydropower stations in southwest China are located in regions of brittle rock mass with high geo-stresses. Under these conditions deep fractured zones often occur in the sidewalls of the underground caverns of a power station. The theory and methods of fracture and damage mechanics are therefore adopted to study the phenomena. First a flexibility matrix is developed to describe initial geometric imperfections of a jointed rock mass. This model takes into account the area and orientation of the fractured surfaces of multiple joint sets, as well as spacing and density of joints. Using the assumption of the equivalent strain principle, a damage constitutive model is established based on the brittle fracture criterion. In addition the theory of fracture mechanics is applied to analyze the occurrence of secondary cracks during a cavern excavation. The failure criterion, for rock bridge coalescence and the damage evolution equation, has been derived and a new sub-program integrated into the FLAC-3D software. The model has then been applied to the stability analysis of an underground cavern group of a hydropower station in Sichuan province, China. The results of this method are compared with those obtained by using a conventional elasto-plastic model and splitting depth calculated by the splitting failure criterion proposed in a previous study. The results are also compared with the depth of the relaxation and fracture zone in the surrounding rock measured by field monitoring. The distribution of the splitting zone obtained both by the proposed model and by the field monitoring measurements are consistent to the validity of the theory developed herein.

• 산경연구논집
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• 제8권6호
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• pp.75-86
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• 2017

Purpose - The purpose of this study is to grasp the concept, characteristics and application status of sharing economy, and to derive a research model based on sharing economic service, and to analyze factors and influences of consumers' intention to reuse of sharing economy. Research design, data, and methodology - The questionnaires were created to examine variables for practical and theoretical implications. After pilot survey, conducted for 24 days from March 10th to April 2st in 2017, total numbers were 377. But 330 copies were used for the analysis with IBM SPSS Statistics 23.0 and IBM SPSS AMOS 23.0. The structural equation model was applied for this. Results - First, sharing economic services remain at an early stage, but it is meaningful to identify the revenue mechanism of the business model of the sharing economic platform. Second, in this study, it is meaningful that we systematized the theoretical structure by examining existing studies on the characteristics of the sharing economic service and consumer characteristics, and by examining empirically. Third, Satisfaction and Reliability are related to the characteristics of Sharing Economic Service (Security, Convenience, Discount, Sharing, Social Interaction), Consumer Characteristics (Personal Innovation, Word-of-Mouth) It is meaningful to broaden the understanding of the factors by verifying the mediating effect. Fourth, the sharing economy business is meaningful in that it is a new consumption trend that changes the meaning of consumption to consumers. Gradually, more and more people are recalling that purchasing something is not consumption, but sharing and borrowing is also consumption. In other words, through the sharing economy, consumers can experience more products and services, have more choices, and are expected to have a positive impact on economic growth by increasing the utilization of idle resources. Conclusions - Currently, the sharing economy is growing rapidly all over the world. Therefore, in the subsequent study, it is necessary to compare Korea and China's sharing economy and study the cultural and social characteristics of Korea and China. In particular, I think that steady research is necessary for more precise and specific direction on the influence of the shared economy.

• Journal of Microbiology and Biotechnology
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• 제27권5호
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• pp.1005-1009
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• 2017

Primary cytomegalovirus (CMV) infection during pregnancy can cause congenital defects. Available data for CMV infection during pregnancy in north China are inadequate. The aim of this study was to evaluate the epidemiology of maternal CMV infection and explore the incidence of congenital infection. In this prospective study, serum CMV IgG and IgM antibodies were measured in 2,887 pregnant women using ELISA, and the IgG avidity test was performed on all IgM-positive subjects. The seroprevalence of anti-CMV IgG was 94.70%, and of anti-CMV IgM was 1.28%. CMV IgG prevalence increased significantly with age (p < 0.01). Women living in downtown areas showed higher IgG prevalence than those residing in urban areas (p = 0.023). CMV-IgM seroprevalence was highest in autumn (p = 0.021). There was no difference in IgM seroprevalence by age, socioeconomic status, geographical area, or gravida. The rate of primary CMV infection was 0.45% (13/2,887) at the first trimester. The seroconversion rate during pregnancy was 0.76% (22/2,887). One woman underwent seroconversion during pregnancy and gave birth to an infant with asymptomatic CMV infection. Congenital CMV infection was diagnosed in five of the 14 infants from 14 mothers with active infection, for a vertical transmission rate of 35.71% (5/14). Three infants were asymptomatic, whereas two infants presented symptomatic infection with hearing deficits. Although CMV IgG prevalence is relatively high in north China, significant attention to primary CMV infection during pregnancy is still needed.

• BMB Reports
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• 제38권5호
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• pp.571-576
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• 2005

Cytokines are proteins produced by many different cells of the immune system and play a significant role in initiating and regulating the inflammatory process. In this research, an important cytokine, interleukin-10 (IL-10) gene, has been identified and characterized from zebrafish (Danio rerio) genome database. Zebrafish IL-10 is located within a 2690 bp fragment and contains five exons and four introns, sharing the same organization with mammalian IL-10 genes. An open reading frame of 543 bp was found to encode a putative 180 amino acid protein with a signal peptide of 22 amino acids, which shares 29.7-80.9% homology with amino acid sequences of other known IL-10. The signature motif of IL-10 is also conserved in zebrafish IL-10. The predicted transcript was finally confirmed by sequencing of cDNA clones. Multi-tissue reverse transcriptase PCR (RT-PCR) was performed to examine the tissue distribution and expression regulation of this gene in seven organs of normal and lipopolysaccharide (LPS) stimulation zebrafish. The results demonstrated that this gene was expressed slightly in normal kidney, gill and gut, no expression was detected in other four tissues. The expression was clearly upregulated after LPS stimulation. Using the ideal zebrafish model, further study of IL-10 characterization and function may provide insight on the understanding of the innate immune system.

• 한국디지털건축인테리어학회논문집
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• 제6권1호
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• pp.5-11
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• 2006

Korea and China have had close relations not only geographically but also ideally and culturally throughout history. Regarding their lifestyles on housing patterns, however, Koreans had a sedentary way of life, usually sitting on the floor while Chinese had a standing lifestyle, sitting on a chair. This paper tries to have a comparative analysis on similarities and distinctions of two countries' traditional furniture that had complied with each lifestyle. This paper also aims to explore the similarities and distinctions of the form and function of the traditional furniture of the two countries and then to put results of this paper in design and plan of modern furniture and housing in our times. The study can be summarized as follows. Even if, cultural and historical relationships of two countries, there is a different of traditional furniture's forms and types. The major differences are as following : Korean furniture is predominantly on the floor level with storing furniture while Chinese one is intermixed with seat-level and floor level styles. These characters seem to be derived from their own housing and life style. In Ming and Qing period China, Their developed in which intermediate people and building. But, in Korea their housing style had floating floor against wet earth, which finished woods, Ondol. Because of these finishing, the Korean traditional furniture was developed into a good form and a suitable dimension for moving. These differences in furnishing style seemed to well reflect building and housing style of each country. And Image map and positioning map can show the differences in a whole aspect.

• Asian Pacific Journal of Cancer Prevention
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• 제15권8호
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• pp.3635-3640
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• 2014

Aim: To determine whether induced abortion (IA) increases breast cancer (BC) risk. Materials and Methods: A population-based case-control study was performed from Dec, 2000 to November, 2004 in Shanghai, China, where IA could be verified through the family planning network and client medical records. Structured questionnaires were completed by 1,517 cases with primary invasive epithelial breast cancer and 1,573 controls frequency-matched to cases for age group. The information was supplemented and verified by the family planning records. Statistical analysis was conducted with SAS 9.0. Results: After adjusting for potential confounders, induced abortions were not found to be associated with breast cancer with OR=0.94 (95%CI= 0.79-1.11). Compared to parous women without induced abortion, parous women with 3 or more times induced abortion (OR=0.66, 95%CI=0.46 to 0.95) and women with 3 or more times induced abortion after the first live birth (OR=0.66, 95%CI =0.45 to 0.97) showed a lower risk of breast cancer, after adjustment for age, level of education, annual income per capita, age at menarche, menopause, parity times, spontaneous abortion, age at first live birth, breast-feeding, oral contraceptives, hormones drug, breast disease, BMI, drinking alcohol, drinking tea, taking vitamin/calcium tablet, physical activity, vocation, history of breast cancer, eating the bean. Conclusions: The results suggest that a history of induced abortions may not increase the risk of breast cancer.

• 한국한의학연구원논문집
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• 제15권3호
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• pp.63-74
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• 2009

Background and Purpose : Oncheongeum(溫淸飮) composed of Samultang(四物湯) and Hwangryunhaedoktang(黃連解毒湯) was mainly used for healing metrorrhagia in the Qing dynasty of China. At present, Oncheongeum is used for treating a broad spectrum of diseases such as skin disease, stomatitis, behcets disease, diabetes mellitus and, especially in Japan, atopic dermatitis. To our knowledge, however, neither the precise constituents and their effects of Oncheongeum nor the criteria for the prescription of Oncheongeum were defined. To address this issue, we searched and performed analysis of Korean, Chinese and Japanese articles reporting the clinical and experimental studies of Oncheongeum. Methods : We searched articles in the national assembly library of Korea by using keyword 'Oncheongeum' korean. Similarly, we did chinese articles in the CNKI and japanese ones in the CiNii, respectively. Results : We found 13 korean articles about Oncheongeum in the national assembly library, 34 chinese articles in the CNKI, and 23 japanese in the CiNii. The papers were divided into clinical and experimental articles. The clinical articles were mainly published from China and Japan, and their subjects were predominantly on skin diseases. Conclusions : There were a lot of case reports about Oncheongeum used in the clinical studies. In order to better understand the effects of Oncheongeum, systematic review of the studies seems essential. The efficacy of Oncheongeum reported in the clinical studies should be supported by experimental data. Not much were clinical reports in Korea, although we are expecting more to come. It is possible to not only analyse but compare Oncheongeum with other prescriptions used for atopic dermatitis. More comprehensive and comparative analysis of three countries' prescriptions might provide a way of how to standardize prescriptions, which leads oriental medicine to an evidence based medicine.

• Parasites, Hosts and Diseases
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• 제58권2호
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• pp.181-184
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• 2020

Blastocystis, an enteric protist, has been reported to be an important cause of protozoal gastrointestinal manifestations in humans and animals worldwide. Animals harboring certain Blastocystis subtypes (STs) may serve as a potential source of human infection. However, information about the prevalence and genetic diversity of Blastocystis in alpacas is limited. In the present study, a total of 366 fecal samples from alpacas in Shanxi Province, northern China, were examined for Blastocystis by PCR amplification of the small subunit rRNA gene, followed by sequencing and phylogenetic analysis. The prevalence of Blastocystis in alpacas was 23.8%, and gender difference in the prevalence of Blastocystis was observed. The most predominant Blastocystis ST was ST10, followed by ST14 and ST5. The detection of ST5, a potentially zoonotic genotype, indicates that alpacas harboring ST5 could be a potential source of human infection with Blastocystis. These data provide new insight into the prevalence and genetic diversity of Blastocystis in alpacas.

• 디지털융복합연구
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• 제17권6호
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• pp.43-49
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• 2019

본 연구는 중국기업의 기업수명주기를 성장기, 성숙기, 쇠퇴기 등 3단계로 구분하여 2011년부터 2017년까지 중국 중소상장기업(SME) 3,750개를 대상으로 공시데이터를 활용하여 기업수명주기별 연구개발투자강도(매출액 대비 연구개발비 총액)가 경영성과(총자산이익률)에 미치는 영향에 대해 실증 분석하였다. 분석결과, 연구개발투자강도(RDS)과 차기(t년도)의 기업 경영성과(ROA)에 부(-)의 영향을 미치는 것으로 분석되었고 기업수명주기에 따라 연구개발투자가 기업의 경영성과에 다르게 영향을 미치는 것으로 분석되었다. 본 연구의 실증결과는 기업의 연구개발투자와 관련한 전략적 의사결정을 할 때 산업특성 및 기업특성을 고려하여 연구개발투자와 관련한 지출 규모, 자원을 투입 시간 등을 결정하는데 있어서 도움을 줄 것으로 기대한다.

• 대한본초학회지
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• 제28권5호
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• pp.13-19
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• 2013

Objectives : The purpose of this study is correct the scientific name of Aquilariae Lignum in Korean Herbal Pharmacoepia. Methods : The production areas of Aquilariae Lignum and its trading status with China in Chinese history, Sanscrit-Chinese Translation Sutra, Naming year and the discovered district in main Aquilaria spp., Several nation's Pharmacoepia, The Plant List(TPL), Convention on International Trade in Endangered Species of Wild fauna and flora(CITES) and The International Union for Conservation of Nature(IUCN) were cross-checked. Results : The records in the Jiaozhouyiwuzhi written in the early 2nd century said that Aquilariae Lignum was produced in Vietnam. NanfangCaomuZhuang written in 304 said that Agarwood in Vietnam had white flowers. Vietnam had led production and trading of Aquilariae Lignum until Qing Dynasty. Aquilariae Lignum from Malaysia and Indonesia was not traded with China. In Sanscrit-Chinese Translation Sutra, India Aquilariae Lignum was translated as Vietnam Aquilariae Lignum. Aquilaria malaccensis was discovered from Malay-Peninsular in 1783, and has green or dirty yellow flowers. A. agallocha from North-Eastern India in 1814, white flowers. A. crasssna from Vietnam in 1914, white flowers. A. crassna is different from A. malaccensis in several ways, such as flower, fruit, seed and disribution. In several Nation's Pharmacoepia, A. crassna was a synonym of A. agallocha. But in TPL, CITES and IUCN, A. malaccensis was an accepted name, and A. agallocha was a synonym of A. malaccensis. Conclusions : These results show that the original species of Aquilariae Lignum in Korea Herbal Pharmacoepia should be reversed from A. agallocha to A. crassna Pierre ex Lacomte.