• 제목/요약/키워드: QT

검색결과 243건 처리시간 0.024초

토러스 구조와 하이퍼-토러스 구조 상호간 임베딩 정도의 분석 (An Analysis of the Degree of Embedding between Torus Structure and Hyper-Torus One)

  • 김종석;이형옥
    • 한국정보통신학회논문지
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    • 제18권5호
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    • pp.1116-1121
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    • 2014
  • 메쉬 구조는 대표적인 상호연결망 중 하나로, VLSI 회로 설계 같은 분야에서 많이 이용되고 있다. 이러한 메쉬 구조에서 지름과 고장허용도를 개선한 연결망으로 토러스와 하이퍼-토러스 연결망이 있다. 본 논문에서는 토러스 구조 T(4k,2l)와 하이퍼-토러스 네트워크 QT(m,n) 사이의 임베딩을 분석한다. 토러스 T(4k,2l)는 QT(m,n)에 연장율 5, 밀집율 4, 확장율 1에 임베딩 가능하고, QT(m,n)은 T(4k,2l)에 연장율 3, 밀집율 3, 확장율 1에 임베딩 가능함을 보인다.

Cloning and Expression of Human KCNE1 Gene

  • ;;;유민
    • 대한의생명과학회지
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    • 제16권4호
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    • pp.299-305
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    • 2010
  • KCNE1 is the causal gene of long QT syndrome. KCNE1 gene is located in chromosome 21. In compliance with this KCNE1 gene the proteins come out. KCNE1 is responsible for $K^+$ channel which maintains the normal function of the heart muscle for contraction. Affected individuals manifest prolongation of the QT interval on electrocardiongrams, a sign of abnormal cardiac repolarization. The clinical features of LQT result from episodic cardiac arrhythmias, such as torsade de pointes and ventricular fibrllation. Blood DNA was isolated and kept in $4^{\circ}C$ refrigerator. The KCNE1 gene was amplified by PCR method and about 414 bp band was identified by agarose gel electrophoresis. PCR products were inserted into pGEX-4T-1 vector in order to express KCNE1 protein after treatment with IPTG SDS-PAGE was carried out and the protein band which was about 47 kDa was clearly odserved. Results of this study would contribute to the detailed understanding of KCNE1 protein function and to designing better treatment of Long QT symdrome.

Preparation and Antitumor Activity of a Tamibarotene-Furoxan Derivative

  • Wang, Xue-Jian;Duan, Yu;Li, Zong-Tao;Feng, Jin-Hong;Pan, Xiang-Po;Zhang, Xiu-Rong;Shi, Li-Hong;Zhang, Tao
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권15호
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    • pp.6343-6347
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    • 2014
  • Multi-target drug design, in which drugs are designed as single molecules to simultaneously modulate multiple physiological targets, is an important strategy in the field of drug discovery. QT-011, a tamibarotene-furoxan derivative, was here prepared and proposed to exert synergistic effects on antileukemia by releasing nitric oxide and tamibarotene. Compared with tamibarotene itself, QT-011 displayed stronger antiproliferative effects on U937 and HL-60 cells and was more effective evaluated in a nude mice U937 xenograft model in vivo. In addition, QT-011 could release nitric oxide which might contribute to the antiproliferative activity. Autodocking assays showed that QT-011 fits well with the hydrophobic pocket of retinoic acid receptors. Taken together, these results suggest that QT-011 might be a highly effective derivative of tamibarotene and a potential candidate compound as antileukemia agent.

QT/임베디드 기반의 화상 감시시스템 설계 몇 구현 (Design and Implementation for Image Monitoring System using Qt/Embedded)

  • 노방현
    • 한국산학기술학회논문지
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    • 제5권3호
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    • pp.236-240
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    • 2004
  • PXA255 프로세서 기반의 내장형 보드에 QT/Embedded 2.3.7 버전을 포팅하여 원격지의 화상 감시 시스템을 구현하였다. 클라이언트 단말기로서의 역할을 하는 PXA255보드에서 이더넷 통신방법에 의해 원거리의 의 Host PC로 접속하여 PC에 연결되어 있는 카메라 영상을 확인할 수 있도록 하였다. 또한 PCI 인터페이스 카드를 설계하여 카메라의 Pan/Tilt 에 대한 모터제어가 가능하도록 하였다. 즉, 320×240크기의 컬러 비트맵 형식의 영상을 타깃보드의 TFT-LCD화면으로 출력하고 사용자가 터치스크린 입력방식으로 Pan/Tilt 에 대한 원하는 위치를 선택하면 호스트 PC의 모터가 회전함으로서 원하는 위치의 영상을 감시할 수 있도록 하였다.

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Concealed congenital long QT syndrome during velopharyngeal dysfunction correction: a case report

  • Jeon, Soeun;Lee, Hyeon-Jeong;Jung, Young-hoon;Do, Wangseok;Cho, Ah-Reum;Baik, Jiseok;Lee, Do-Won;Kim, Eun-Jung;Kim, Eunsoo;Hong, Jeong-Min
    • Journal of Dental Anesthesia and Pain Medicine
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    • 제20권3호
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    • pp.165-171
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    • 2020
  • The congenital long QT syndrome (LQTS) is an inherited cardiac disorder characterized by increased QT intervals and a tendency to experience ventricular tachycardia, which can cause fainting, heart failure, or sudden death. A 4-year-old female patient undergoing velopharyngeal correction surgery under general anesthesia suddenly developed Torsades de pointes. Although the patient spontaneously resolved to sinus rhythm without treatment, subsequent QT prolongation persisted. Here, we report a case of concealed LQTS with a literature review.

내장형 리눅스 시스템상에서 EBKS용 전자책 리더 시스템의 개발 (Development of an E-Book Reader System for EBKS on Embedded Linux System)

  • 김정원;노영욱
    • 정보처리학회논문지A
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    • 제9A권4호
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    • pp.421-428
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    • 2002
  • 본 논문에서는 내장형 리눅스 환경에서 XML기반 EBKS용 전자책 리더 시스템을 개발하였다. 개발된 시스템은 내장형 리눅스 타겟보드 상에서 Qt SAX 파서를 이용하여 한국형 전자책 문서 표준에 기반한 XML 문서를 파싱하고, 크로스플랫폼형 윈도우 시스템인 QWS(Qt Windows system)를 이용하여 디스플레이 한다. 개발된 전자책 리더는 리눅스 환경뿐만 아니라 다양한 윈도우 플랫폼(MS 윈도즈 등)에서 신속하게 그리고 쉽게 개발 가능하며, SAX 파서를 사용하므로 DOM 인터페이스에 비해 메모리 소요량이 감소함을 확인하였다.

적응적 결함-허용 다단계 상호연결망 (Adaptive Fault-tolerant Multistage Interconnection Network)

  • 김금호;김영만;배은호;윤성대
    • 대한전자공학회:학술대회논문집
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    • 대한전자공학회 2001년도 하계종합학술대회 논문집(3)
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    • pp.199-202
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    • 2001
  • In this paper, we proposed and analyzed a new class of irregular fault-tolerant multistage interconnection network named as Extended-QT(Quad Tree) network. E-QT network is extended QT network. A unique path MIN usually is low hardware complexity and control algorithm. So we proposes a class of multipath MIN which are obtained by adding self-loop auxiliary links at the a1l stages in QT(Quad Tree) networks so that they can provide more paths between each source-destination pair. The routing of proposed structure is adaptived and is based by a routing tag. Starting with the routing tag for the minimum path between a given source-destination pair, routing algorithm uses a set of rules to select switches and modify routing tag. Trying the self-loop auxiliary link when both of the output links are unavailable. If the trying is failure, the packet discard. In simulation, an index of performance called reliability and cost are introduced to compare different kinds of MINs. As a result, the prouosed MINs have better capacity than 07 networks.

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Complete Nucleotide Sequence of KCNE1 in Korean Genome

  • Yeo, Shin-Il;Kim, Su-Won;Kim, Yoon-Nyun;You, Kwan-Hee;Shin, Song-Woo;Kim, Myoung-Hee;Song, Jae-Chan;Yoo, Min
    • 대한의생명과학회지
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    • 제8권3호
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    • pp.185-188
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    • 2002
  • We have cloned the gene fur long QT syndrome in Korean genome and determined its detailed nucleotide sequence. Blood DNAs were isolated from 68 healthy individuals (including males and females) and the genomic DNAs were amplified by PCR method followed by automatic DNA sequencing. Entire sequence of the coding region for KCNEI was located in exon 3. PCR products were reexamined for the confirmation of KCNE1-specific amplification by nested PCR. KCNE1 mRNA was 436 bp. This corresponded to 129 amino acids. There was no recognizable difference between males and females. This study should contribute to the better understanding of long QT syndrome in Korean population.

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Long QT 증후군 환자에게 시행한 좌측 흉부 교감신경절 절제술 -1례 보고- (Left Thoracic Sympathetic Ganglionectomy with Thoracoscope for the Treatment of the Long QT Syndrome -A case report-)

  • 홍남기;정태은;이정철;한승세;이동협
    • Journal of Chest Surgery
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    • 제33권9호
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    • pp.766-769
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    • 2000
  • The long QT syndromes have been classified into acquired or inheritary forms, both of which are associated with a characteristic type of life-threatening polymorphic ventricular tachycardia called torsade de points. Beta-adrenergic blocker is the first cholic treatment, but in those whom cardiac events are not prevented by $\beta$-blockade, left thoracic sympathetic ganglionectomy may be useful in selected cases. A 50-year-old woman had an recurrent syncopal attack in which she was unconscious for 1-2 min and 1-2 times a month for 10 years. The EKG revealed that QT & QTc intervals were 744 and 632 msec respectively. Treatment with Beta-adrenergic blocker and calcium channel blocker was ineffective in preventing recurrence of syncopal spell. Therefore, she underwent left thoracic sympathetic ganglionectomy with thoracoscope. During the 9 months after operation, she was free of syncopal episodes and is doing well.

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