• Title/Summary/Keyword: QM

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Tyrosinase Inhibition Effect of extracts from Mistletoe Cultivated on Prunus mume (매실나무(Prunus mume) 겨우살이 추출물의 tyrosinase 저해활성)

  • Heo, Jeong Won;Azad, Md Obyedul Kalam;Park, Cheol Ho
    • Proceedings of the Plant Resources Society of Korea Conference
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    • 2018.04a
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    • pp.84-84
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    • 2018
  • 인공재배 매실나무겨우살이의 의약 화장품의 소재 및 산업화 가능성을 검토하기 위해 80% 에탄올 및 증류수 초음파추출물의 Tyrosinase 저해활성을 측정하였다. 인공재배한 매실나무겨우살이(PM, 동결건조) 및 자연산 굴참나무겨우살이(QM, 열풍건조, $30^{\circ}C$, 7day)의 80% 에탄올, 증류수 초음파추출물에 대한 tyrosinase 저해활성을 측정한 결과, 물 추출물의 경우 100 ppm의 농도에서 PM과 QM 모두 5분이 경과 하였을 때 PM은 88.37%, QM은 87.69%로 최대치를 나타내었고, 농도와 시간이 증가함에 따라 tyrosinase 저해활성이 감소하는 경향을 보여주었다. PM 80% 에탄올 추출물은 5분이 경과하였을 때 2,500ppm이 92.08%로 최대값을 보여주었고 이후 시간이 지남에 따라 저해활성이 감소되는 경향을 나타내었다. 반면 5,000ppm은 5분이 경과하였을 때 66.38%로 최소값을 나타낸 반면, 20분까지 저해활성이 증가하였고 10분이 경과한 이후로 거의 일정하게 유지되어 지속적으로 감소되는 1,000ppm보다 높은 저해효과를 보여 주었다. QM 80% 에탄올 추출물은 5분이 경과하였을 때 1,000ppm이 88.14%로 가장 높았고 5,000ppm은 63.49%로 가장 낮은 저해활성을 보여주었다. 15분까지 1,000ppm이 가장 높은 저해활성을 보여주었으나 꾸준히 감소한 반면, 2,500ppm의 경우 시간이 경과함에 따라 비교적 일정한 저해활성을 보여주어 15분이 경과한 이후로 2,500ppm의 저해활성이 가장 높게 나타났다. 25분이 경과하였을 때 2,500ppm은 70.27%로 가장 높은 저해활성을 나타내었고, 5,000ppm은 30.09%로 가장 낮은 저해활성을 보여주었다. 본 연구 결과에 따르면, 물 추출물의 경우 겨우살이의 농도가 낮을수록 더 높은 tyrosinase 저해활성을 나타내었고, 80% 에탄올 추출물의 경우 2,500ppm에서 가장 높은 저해활성을 나타내어 의약 화장품의 소재 및 산업화 가능성이 높음을 확인할 수 있었다.

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Aspects of Cellulase Induction by Sophorose in Trichoderma reesei QM9414 (Trichoderma reesei QM9414의 sophorose에 의한 섬유소 분해효소 유도현상에 관하여)

  • 정종문;박희문;홍순우;하영칠
    • Korean Journal of Microbiology
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    • v.23 no.2
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    • pp.77-83
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    • 1985
  • The aim of this investigation was to resolve the contradiction between the results of Sternberg and Mandels (1980, 1982)and those of Nisizawa et al., (1971) in cellulase induction by sophorose, and furthermore to study the conditional effects in sophorose-induced cellulase induction in Trichoderma reesei QM 9414. Sophorose could induce the synthesis of CMCase and ${\beta}-glucosidase$ simultaneously. Optimal induction medium by sophorose had the potassium citrate buffer solution of pH 3.0-4.0 for CMCase, but one of pH 5.0-6.0 for ${\beta}-glucosidase$. At this time, two different types of ${\beta}-glucosidase$ could be induced by sophorose: one was extracellular and had maximum at pH 5.0, the other was intracellular and had maximum activity at pH6.5. Induction study showed that $methyl-{\beta}-glucoside$ was not a true inducer of ${\beta}-glucosidase$ and that large ${\beta}-glucosidase$ induction could be obtained only by the addition of sophorose into the induction medium. Glucose repressed the induction of cellulase by sophorose. The repression of glucose could not be overcome by the addition of cyclic AMP into the induction medium.

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Isolation and Characterization of Regulatory Mutant for Cellulase Production from Trichoderma reesei QM 9414 (Trichoderma reesei QM 9414의 섬유소 분해 호소 생산을 위한 조절변이주의 분리 및 특성에 관한 연구)

  • Choi, Kun-Ho;Koo, Youn-Mo;So, Jae-Seong
    • The Korean Journal of Mycology
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    • v.26 no.1 s.84
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    • pp.127-133
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    • 1998
  • Two regulatory mutants of Trichoderma reesei QM 9414 were isolated by treatment with N-methyl-N'-nitro-N-nitrosoguanidine, and the effects of various inducers on the carboxymethyIcellulose (CMC) and filter paper (FP) production were investigated. Induction of CMCase and FPase production of mutants was shown higher level than wild type strain in 1% lactose minimal broth. When induced by glucose, wild type showed glucose-repression for CMCase and FPase production and mutants showed glucose-derepression. Mutant 1 showed 8.38 fold higher CMCase activity and 5.68 fold higher FPase activity than wild type stain. Mutant 2 showed about 8.42 fold higher CMCase activity and 5.41 fold higher FPase activity than wild type strain. Enzyme activities from the mutants and wild type had the same optimum pH of 4.8 and optimum temperature of $60^{\circ}C$.

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Quality Management (QM) Standard Issues in FM - Based on Guidance on quality in European FM Standard

  • Lee, So Young;Jang, Yon Hwa;Lee, Myoung Sik
    • Architectural research
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    • v.18 no.1
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    • pp.21-29
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    • 2016
  • Importance of FM has rapidly increased because of its growing business. However, due to lack of clarity and identity of FM in professional areas, standardization of FM became to be imperative in such a rapidly changing global business environment. Facility services are defined as the provision of support the primary activities of an organization, delivered by an internal or external provider. Majority of FM activities are services related to 'space and infrastructure' and 'people and organization' (CEN, 2011). The purpose of this study is to investigate definitions and characteristics of FM from both globally and domestic environment, by comparison with international or national standards, to identify quality management in FM and service characteristics of FM, to investigate the differences in service level elaboration in FM, and to suggest standard issues of quality management in FM service quality. This study examines contents of the European Standards in FM, Part 3 'Guidance on quality in Facility Management, especially for the process of QM standardized by CEN (2011) and explores undefined issues such as service level, measurement metrics according to service characteristics of FM. The European FM Standard guides the common process of QM in terms of requirements specification, service level elaboration, measurement metrics development although it does not specifically address various service levels, specific performance metrics and indicators.

An Empirical Study on the QM Efficiency Influence Factors in 100ppm Corporates (100ppm 기업의 QM 효율성 영향요인에 관한 실증연)

  • Lee, Soon-Ryoung;Kim, Oh-Woo;Lee, Jong-Ho
    • Journal of Korean Society for Quality Management
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    • v.28 no.4
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    • pp.1-15
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    • 2000
  • Nowadays, consumers' consciousness on me quality are very diversified and their pattern is changing from the price-priority to me quality-priority. So they prefer good-quality products without defects. Therefore quality is a core competence. To compete with me facts, it is very important to keep me the quality competence. To do so, one way is to introduce 100ppm quality innovation system. Many corporates introducing 100ppm improved defect rations(not only process defect ratios but also product defect ratios). In these respects, this study focuses on the comparison and measurement of performance by the analysis of quality system between 100ppm corporates and non-100ppm corporates. Second, this focuses on the finding out core competence reinforcement factors according to the introducing of 100ppm quality system to improve the performance. Third, this focuses on the persuading to introduce the 100ppm quality system to the non-100ppm corporates. Last, this focuses on the playing on the role of guidance to improve QM efficiency.

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Effect of Composition Size of Sintered Body and Electrode on Resonant Characteristics of $Pb(Mn_{1/3}Nb_{2/3})O_3 PbTiO_3-PbZrO_3$ Piezoelectric Ceramics (소결체 및 전극의 크기와 조성이 $Pb(Mn_{1/3}Nb_{2/3})O_3 PbTiO_3-PbZrO_3$계 압전세라믹스의 공진특성에 미치는 영향)

  • 류영대;조상희
    • Journal of the Korean Ceramic Society
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    • v.23 no.1
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    • pp.60-66
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    • 1986
  • The effect of composition size of sintered body and electrode on resonant characteristics of the system $Pb(Mn_{1/3}Nb_{2/3})O_3 PbTiO_3-PbZrO_3$ has been decribed. Composition ranged from X=40 to X=55 diameter of sintered body ranged from D=6.5 to D=12.5(mm) and diameter of electrode ranged from De=5.5 to De=11 (mm) In the composition of morphotropic phase boundary antiresonant frequency (fa) dcreased slowly whereas resonant frequency (fr) decreased rapidly on the ground of this Δf(fa-fr) and electromechanical coupling fractor Kp increased and Qm showed low value. On the contrary in toward the composition of tetragonal and rhombo-hedral fa increased slowly whereas fr increased rapidly on the ground of this Δf and Kp decreased and Qm increased abruptly. Substance of the above statements have no concern with size of sintered body and ele-ctrode. The other side as the size of electrode decreased Qm fr, fa and Δf increased. Cm and Co dominantly affect the resonant frequency and antiresonant frequency.

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A Case Study of Quality Management System Computerization with SAP QM Module & Mobile Office Construction (품질경영 성과 향상을 위한 ERP QM모듈 및 모바일 오피스 기반의 품질경영시스템 구축에 관한 연구 - A사(社) 사례(事例)를 중심(中心)으로-)

  • Kwon, Oh-Hyun;Park, Yong-Tae
    • The Journal of Information Systems
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    • v.23 no.2
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    • pp.49-66
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    • 2014
  • In today's competitive business environment it is a necessary condition for a company to produce high-quality product for its survival and growth. That is the case in the auto-part industry as well where the international standards, ISO/TS 16949 certification, are required by customers to adopt mandatory. This study presents a successful implementation of quality management system(QMS) in a major auto-part manufacturer in Korea, utilizing SAP's QM(qualaity management) module and a mobile office system. The QMS brought the company "A" a variety of benefits such as real-time availability of product-inspection data, speedy decision-making, reduction in time required for defect-handling, ease of vertical integration of business partners in supply chain, and ease of business process standardization between headquarters and overseas subsidiaries. It is expected that the findings of this study can be used as a useful guideline for companies to consider implementing ERP-based quality management systems successfully.

Characterization of Heading- and Yield-related Gene Loci in the Cheongcheong/Nagdong Doubled Haploid Line using Rice QTLs (청청/낙동 배가반수체 집단에서 QTL을 통한 출수기와 수량관련 유전자좌 분석)

  • Jang, Yoon-Hee;Park, Jae-Ryoung;Kim, Kyung-Min
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.64 no.1
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    • pp.1-17
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    • 2019
  • A quantitative trait loci (QTL) analysis of traits related to heading and yield was performed develop rice cultivars that are both early maturing and panicle weight type varieties. Our analysis included 120 strains of the Cheongcheong Nagdong doubled haploid (CNDH) variety. An observational growth experiment was conducted to identify genetic agronomic traits of CNDH. Heading date, ten plant weight, moisture, thousand grain weight, and yield had a normal distribution based on the frequency distribution table of the observational growth data. The QTL analysis found one heading-related and nine yield-related QTLs. The LOD of 2.85 was the largest in QTLs for heading date (QHD), 5.39 in QTLs for ten plant weight (QTPW), 3.92 in QTLs for moisture (QM), 4.80 in QTLs for thousand grain weight (QTGW), and 3.7 in QTLs for yield (QY). Genomic analysis detected 58 candidate genes on chromosome 2, 3, 7, 8, and 10. Among those, we found Rcd1 protein and OsERF3 gene in QM, MtN3 and zinc finger protein genes in QTGW, and OsNAC3 protein gene in QY. If further analysis reveals the presence of genes related to water content, thousand grain weight or yield in the CNDH stains, we can develop a selection of varieties that will be capable of coping with climate change and will contribute to global food problems.