• Title/Summary/Keyword: Q4A

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Effects of Dietary Coenzyme $Q_10$ and Vitamin E on Lipid Peroxidation in Adriamycin-treated Rat (Coenzyme $Q_10$과 Vitamin E 첨가식이가 Adriamycin을 투여한 흰쥐의 체내 지질과산화에 미치는 영향)

  • 서정숙;양경미;정영아
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.20 no.4
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    • pp.320-328
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    • 1991
  • The present study was designed to evaluate the effects of dietary vitamin E and coenzyme $Q_{10}$ supplementation on adriamycin (ADR) -induced lipid petoxidation in rats. After feeding the experimental diets for e weeks. Ann treatment significantly decreased growth performance of rats. But this decrement was not modified by supplementation of vitamin E or coenzyme $Q_{10}$ . Lipid peroxide values of plasma and heart mitochondria were elevated by Ann treatment. But these values were significantly decreased according to vitamin E or coenzyme $Q_{10}$ supplementation. Adriamycin treatment elevated glutathione peroxidase (GSH-Px) activity of rats, but this increment was modified by vitamin E supplementation. There was a tendency of higher superoxide dismutase (SOD) activity in ADR-treated rats. However, vitamin E or coenzyme $Q_{10}$ administration reduced this enzyme activity. With ADR treatment, arachidonic acid (20 : 4) was greatly increased, but docosahexaenoic acid (22 : 6) was not detected. Arachidonic acid was decreased and docosahexaenoic acid increased by supplementation of higher level of vitamin E or coenzyme $Q_{10}$ . Present data showed that dietary vitamin E and coenzyme $Q_{10}$ influenced on ADR-induced lipid peroxidation in rats, and also the degree of antioxidative effect was greater in vitamin E-supplemented rats.

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A Study into Pattern of Smoking Behavior of University Students (대학생의 흡연행위 유형에 대한 연구)

  • 김문실;김애경
    • Journal of Korean Academy of Nursing
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    • v.27 no.4
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    • pp.843-856
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    • 1997
  • The purpose of this study was to explore the subjective opinions related to of smoking behavior of university students with a history of smoking. The research period was from Feb, 1. 1996 to Sep. 10. 1997. The research method used was Q-methodology. The process of the research was as follows : 1. Collection of concourse : The statement of self-reference was derived from face to face interviews with 50 university students. Statement were categorized by researcher according to semantics. 2. Extraction of Q-sample : 38 of the self-reference statements from the 32 categories of the Q-population were selected. 3. Selection of P-sample : 30 of university students were selected by consideration of diversity in sociodemographic background. 4. Based on a 1 to 9 point scale, the selected university students were made to participate in Q-sorting. 5. Analysis of Q-type was obtained by use of the QUANAL program. The results of this study revealed as follows : There are three types of smoking behavior of Korean university students. 1. The first type focused on the right of the individual to smoke and the lack of recognition of smoking behavior as a health hazard. 2. The second type cared about smoking behavior as a hazard to health. 3. The third type was habitual smoker. They are bored and smoke habitually. It is suggested that the results of this study may contribute to the development of strategies for the purpose of decreasing the incidence of smoking of university students.

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Patent Foramen Ovale Complicated with Chronic Mitral Valvular Insufficiency in A Mixed Dog (잡종 개에서 이첨판 폐쇄 부전증이 합병된 난원공 개존증)

  • Lee, Dong-Guk;Han, Suk-Hee;Hyun, Changbaig
    • Journal of Veterinary Clinics
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    • v.30 no.6
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    • pp.468-472
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    • 2013
  • A 12-year-old intact female mixed dog (weighing 6.2 kg) was referred with primary complaints of severe abdominal distension, persistent coughing and exercise intolerance. Diagnostic studies found ascites, jugular distension, loud left and right apical systolic (grade 4/6) murmur, generalized cardiomegaly with caudal vena cava distension and left atrial dilation. Echocardiographic findings were consistent with degenerative mitral and tricuspid valve endocardiosis and bi-ventricular congestive heart failure. There was also a left to right shunting patent foramen ovale. The LV systolic function is depressed relative to the degree of volume overload. Based on diagnostic findings, this case was diagnosed as PFO complicated with mitral and tricuspid valve endocardiosis with ISACHC IIIa heart failure. The dog was treated with furosemide (2 mg/kg, q12hr, PO), sildenafil (1 mg/kg, q8hr, PO), pimobendan (0.3 mg/kg, q12hr, PO), enalapril (0.5 mg/kg, q12hr, PO) and spironolactone (1 mg/kg, q12hr). The clinical signs were gradually improved after medical therapy.

A Study on Subjective Recognition of Food-truck Customers Using Q Methodology (Q방법론을 활용한 푸드 트럭 이용고객의 주관적 인식 연구)

  • Kim, Chan-Woo;Jung, In-Yeong
    • The Journal of the Korea Contents Association
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    • v.18 no.8
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    • pp.514-524
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    • 2018
  • This study applied Q methodology to consumers who have experience using food trucks to understand subjective perception of food truck customers. The purpose of this study is to characterize the perceptual structure of food truck customers, to describe characteristics of the types and to suggest some implications. The results of the type analysis are as follows. The first type (N = 10): Food truck zone accessibility preferred type, the second type (N = 8): Complex entertainment experience type, the third type (N = 9) = 3): Fast food preference type. Future research on food trucks, restaurants, and tourism will be based on a variety of literature and empirical studies, and will be revised and supplemented with more detailed Q methodological questions and analytical techniques to analyze the various opinions of respondents in a more concrete and objective manner.

The Determination and Prediction of Pine to Oak Forest Succession in Sugadaira, Central Japan

  • Jun, Kato;Hayashi, Ichiroku
    • The Korean Journal of Ecology
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    • v.26 no.4
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    • pp.155-163
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    • 2003
  • In order to analyze the succession process from a pine forest to an oak forest, the tree growth of Pinus densiflora and Quercus mongolica ssp. crispula was monitored in a permanent quadrat for 23 years. The measurements were carried out for the stem diameter (DBH) of Pinus densiflora between 1977 and 1999 and for the height of Quercus mongolica ssp. crispula saplings between 1998 and 2000. The floristic composition and the locations of the individual P. densiflora and Q. mongolica ssp. crispula trees and saplings in the quadrat were recorded. P densiflora and Q. mongolica ssp. crispula individuals were randomly distributed within the quadrat. The relative growth rates (RGR) of DBH in P. densiflora were 0.085 $yr^{-1}$ for large trees and 0.056 $yr^{-1}$ for small trees in 1977. The RGR of height for Q. mongolica ssp. crispula was 0.122 $yr^{-1}$. The growth curve for DBH of P. densiflora was approximated by the logistic equation: $$DBH(t) = 30 {[1+1.16exp(-0.13 t)]}^{-1}$$ where DBH (t) the DBH (cm) in year t and t is the number of years since 1977. The growth in height of P. densiflora and Q. mongolica ssp. crispula was described by following equations: $$H (t) = 20.2 {[1+0.407exp(-0.137 t)]}^{-1} (P. densiflora)$$ $$H (t) = 30 {[1+20.7exp(-0.122 t)}^{-1} (Q. mongolica ssp. crispula)$$ Where H (t) is the tree height (m) in year t and t is the number of years since 1977 in P. densiflora and 1998 in Q. mongolica ssp. crispula. With these equations we predicted that the height of Q. mongolica ssp. crispula increases from 2 m in 1999 to 20 m in 2029. Therefore, Q. mongolica ssp. crispula and P. densiflora will be approximately the same height in 2029. The years required for succession from a pine forest to an oak forest are expected 33 with the range between 23 and 44 years.

Chromosome Imbalances and Alterations of AURKA and MYCN Genes in Children with Neuroblastoma

  • Inandiklioglu, Nihal;Yilmaz, Sema;Demirhan, Osman;Erdogan, seyda;Tanyeli, Atila
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.11
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    • pp.5391-5397
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    • 2012
  • Background: Neuroblastoma (NB), like most human cancers, is characterized by genomic instability, manifested at the chromosomal level as allelic gain, loss or rearrangement. Genetics methods, as well as conventional and molecular cytogenetics may provide valuable clues for the identification of target loci and successful search for major genes in neuroblastoma. We aimed to investigate AURKA and MYCN gene rearrangements and the chromosomal aberrations (CAs) to determine the prognosis of neuroblastoma. Methods: We performed cytogenetic analysis by G-banding in 25 cases [11 girls (44%) and 14 boys (66%)] and in 25 controls. Fluorescence in situ hybridization (FISH) with AURKA and MYCN gene probes was also used on interphase nuclei to screen for alterations. Results: Some 18.4% of patient cells exhibited CAs., with a significant difference between patient and control groups in the frequencies (P<0.0001). Some 72% of the cells had structural aberrations, and only 28% had numerical chnages in patients. Structural aberrations consisted of deletions, translocations, breaks and fragility in various chromosomes, 84% and 52% of the patients having deletions and translocations, respectively. Among these expressed CAs, there was a higher frequency at 1q21, 1q32, 2q21, 2q31, 2p24, 4q31, 9q11, 9q22, 13q14, 14q11.2, 14q24, and 15q22 in patients. 32% of the patients had chromosome breaks, most frequently in chromosomes 1, 2, 3, 4, 5, 8, 9, 11, 12, 19 and X. The number of cells with breaks and the genomic damage frequencies were higher in patients (p<0.001). Aneuploidies in chromosomes X, 22, 3, 17 and 18 were most frequently observed. Numerical chromosome abnormalities were distinctive in 10.7% of sex chromosomes. Fragile sites were observed in 16% of our patients. Conclusion: Our data confirmed that there is a close correlation between amplification of the two genes, amplification of MYCN possibly contributing significantly to the oncogenic properties of AURKA. The high frequencies of chromosomal aberrations and amplifications of AURKA and MYCN genes indicate prognostic value in children with neuroblastomas and may point to contributing factors in their development.

Perception Types on the Training System with regard to long-term Care Worker (노인 장기요양인력 양성체계에 관한 인식 연구)

  • Lee, Jae-Hwan
    • The Journal of the Korea Contents Association
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    • v.14 no.8
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    • pp.172-184
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    • 2014
  • The purpose of this study is to find out subjective perception types and needs of interested group on manpower training system with long-term care service by Q methodology, then to search for political measures to improve long-term care system in the implication of the sorted subjective perception types. The result of the study showed that there are five major sorts of subjectivities on manpower training system with long-term care service: emphasizes retraining of existing care worker(Type1), emphasizes ethics of public service provider(Type2), emphasizes practice-oriented education(Type3), emphasizes policy judgement of government(Type4), emphasizes training of long-term care worker in demand(Type5). And to try quantity approach methods, this study was developed Q-Block as a assessment tool to enhance validity and reliability of Q-types. The results of the survey showed high conformity.

A Study on the Production and Decomposition of Litters along Altitude of Mt. Dokyoo (덕유산의 고도에 따른 낙엽의 생산과 분해에 관한 연구)

  • Chang, Nam-Kee;Mi-Ae Chung
    • The Korean Journal of Ecology
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    • v.9 no.4
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    • pp.185-192
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    • 1986
  • The production and decomposition rate of litters from the three different locations, Quercus acutissium forest at 630 m, Q. mongolica forests at 1, 005m and 1, 490 m of Mt. Dokyoo, were estimated by Olson model. The contents of N, P, K, Ca and Na in soils were measured and the relationships among them were elucidated. The amounts of litter production in Q. mangolica were the lowest, 378.96g/$m^2$ at 1, 490 m and the highest, 876.12g/$m^2$ at 1, 005 m. And the amounts of litter production in Q. acutissima at 630 m was 686.16 g/$m^2$. The decay rate of litters in Q. mongolica was the smallest, 0.123 at 1, 490 m, and the largest, 0.222 at 1, 005 m. And that in Q. acutissima was 0.169 at 630 m which was the medium rate. The production and decay rate of litters decreased with the ascending altitude. The values at 630 m were maller than those at 1, 005 m. This might be due to the fact that the tree species at 630 m was Q. acutissima was 0.169 at 630 m which was the medium rate. The production and decay rate of litters decreased with the ascending altitude. The values at 630 m was Q. acutissima which was different from Q. mongolica at 1, 005 m and 1, 490 m. The half-0life of litter decay in Q. monglica was 5, 634 years at 1, 490 m and 3.134 years at 1, 005 m. And that in Q. acutissima was 4.132 years at 630 m. The decay rates of litters were tend to be inversely proportional to the ascending altitude. The annual standing stocks of mineral and their amounts returned to the soil were proportional to the decay rate of organic matters.

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VOLUMES OF GEODESIC BALLS IN HEISENBERG GROUPS ℍ5

  • Kim, Hyeyeon
    • Journal of the Chungcheong Mathematical Society
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    • v.32 no.3
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    • pp.349-363
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    • 2019
  • Let ${\mathbb{H}}^5$ be the 5-dimensional Heisenberg group equipped with a left-invariant metric. In this paper we calculate the volumes of geodesic balls in ${\mathbb{H}}^5$. Let $B_e(R)$ be the geodesic ball with center e (the identity of ${\mathbb{H}}^5$) and radius R in ${\mathbb{H}}^5$. Then, the volume of $B_e(R)$ is given by $${\hfill{12}}Vol(B_e(R))\\{={\frac{4{\pi}^2}{6!}}{\left(p_1(R)+p_4(R){\sin}\;R+p_5(R){\cos}\;R+p_6(R){\displaystyle\smashmargin{2}{\int\nolimits_0}^R}{\frac{{\sin}\;t}{t}}dt\right.}\\{\left.{\hfill{65}}{+q_4(R){\sin}(2R)+q_5(R){\cos}(2R)+q_6(R){\displaystyle\smashmargin{2}{\int\nolimits_0}^{2R}}{\frac{{\sin}\;t}{t}}dt}\right)}$$ where $p_n$ and $q_n$ are polynomials with degree n.

Types of Shared Medical Decision Making for Terminally Ill Patients (말기 환자의 공유 의료적 의사결정에 관한 의료인의 인식 유형)

  • Jo, Kae Hwa;Kim, Gyun Moo
    • Journal of Hospice and Palliative Care
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    • v.17 no.4
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    • pp.278-288
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    • 2014
  • Purpose: The purpose of this study is to analyze types of shared medical decision making by health professionals in a decision making position. Methods: The Q-methodology was used. Q sample was constructed with a total of 35 Q-statements that were offered with a 9-point rating scale. The statements were structured to generate answers that would form a shape of a normal distribution. Answers to Q sample were analyzed using a QUANL PC program. Results: Four types of shared medical decision making were identified. Type I is patient-centered decision making, Type II is physician-centered, Type III is health professional-centered and Type IV is patient-family-centered. Conclusion: Study results indicate that it is recommended to develop an education program based on the four types of shared medical decision making so that health professionals can be provided with different approaches according to their decision making style.