• Proceedings of the Korean Society of Applied Pharmacology
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• 2006.11a
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• pp.139-145
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• 2006

Kaneka Corporation (Kaneka) has been manufacturing CoQ10 under GMP regulation since 1977. Kaneka has a sophisticated quality control system and has been supplying high quality CoQ10 materials to the worldwide customers (Kaneka CoQ10) for about 30 years. Kaneka CoQ10 is characterized by a lot of safety data, which are derived from clinical trials with healthy volunteers (single-dose and 4-week multi-dose safety studies), animal studies (13-week sub-chronic study in dogs and 52-week chronic study in rats), three types of mutagenicity test, six type of skin irritation test (for cosmetics), and others. The risk assessment of CoQ10 was performed by Council for Responsible Nutrition (USA). They reviewed many of available clinical data including clinical trials using Kaneka Q10, and concluded that the upper level for supplements (ULS) of CoQ10 is 1,200 mg/day (Hathcock and Shao. 2006, Regulatory Toxicology and Pharmacology, 45, 282 - 288).

• 한국약용작물학회:학술대회논문집
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• 2006.11a
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• pp.139-145
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• 2006

Kaneka Corporation (Kaneka) has been manufacturing CoQ10 under GMP regulation since 1977. Kaneka has a sophisticated quality control system and has been supplying high quality CoQ10 materials to the worldwide customers (Kaneka CoQ10) for about 30 years. Kaneka CoQ10 is characterized by a lot of safety data, which are derived from clinical trials with healthy volunteers (single-dose and 4-week multi-dose safety studies), animal studies (13-week sub-chronic study in dogs and 52-week chronic study in rats), three types of mutagenicity test, six type of skin irritation test (for cosmetics), and others. The risk assessment of CoQ10 was performed by Council for Responsible Nutrition (USA). They reviewed many of available clinical data including clinical trials using Kaneka Q10, and concluded that the upper level for supplements (ULS) of CoQ10 is 1,200mg/day (Hathcock and Shao. 2006, Regulatory Toxicology and Pharmacology, $\underline{45}$, 282 - 288).

• Kyungpook Mathematical Journal
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• v.47 no.4
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• pp.501-517
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• 2007

In this paper, we introduce and study a new class containing absolutely summing multilinear mappings and polynomials, which we call multiple weakly summing multilinear mappings and polynomials. We investigate some interesting properties about multiple weakly ($p$; $q_1$, ${\cdots}$, $q_k$)-summing multilinear mappings and polynomials defined on Banach spaces: In particular, we prove a kind of Dvoretzky-Rogers' Theorem and an ideal property for multiple weakly ($p$; $q_1$, ${\cdots}$, $q_k$)-summing multilinear mappings and polynomials. We also prove that the Aron-Berner extensions of multiple weakly ($p$; $q_1$, ${\cdots}$, $q_k$)-summing multilinear mappings and polynomials are also multiple weakly ($p$; $q_1$, ${\cdots}$, $q_k$)-summing.

• Journal of the Korea Institute of Military Science and Technology
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• v.15 no.4
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• pp.390-397
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• 2012

According to sailing condition, an exciting force for luminairie of naval vessels was measured and analyzed. A naval combat service support boat and P${\bigcirc}{\bigcirc}$(patrol killer guided missile) were selected as a target naval vessel. Due to their small size and fast speed, they received excessive vibration than other bigger naval vessels like destroyer. The vibration of luminairie was measured on their cruising and maximum speed. This could analyze exciting force for luminairie of naval vessels. Using this analyzed data, the validity of military standard for naval vessel was verified.

• The Journal of Asian Finance, Economics and Business
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• v.4 no.1
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• pp.19-23
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• 2017

Based on a simultaneous-equation model consisting of aggregate demand and short-run aggregate supply, this paper estimates a reduced-form equation specifying that the equilibrium real GDP is a function of the real effective exchange rate, the government deficit as a percent of GDP, the real interest rate, foreign income, labor productivity, the real oil price, the expected inflation rate, and the interactive and intercept binary variables accounting for a potential change in the slope of the real effective exchange rate and shift in the intercept. Applying the exponential GARCH technique, it finds that aggregate output in Australia has a positive relationship with the real effective exchange rate during 2003.Q3 - 2013.Q2, the government deficit as a percent of GDP, U.S. real GDP, labor productivity and the real oil price and a negative relationship with the real effective exchange rate during 2013.Q3 - 2016.Q1, the real lending rate and the expected inflation rate. These results suggest that real appreciation was expansionary before 2013.Q3 whereas real depreciation was expansionary after 2013.Q2 and that more government deficit as a percent of GDP would be helpful to stimulate the economy. Hence, the impact of real appreciation or real depreciation on real GDP may change overtime.

• Korean Chemical Engineering Research
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• v.54 no.1
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• pp.101-107
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• 2016

This paper investigates the feasibility of applying the jet loop reactor for the neutralization of alkaline wastewater using carbon dioxide ($CO_2$). In this study, pH changes and $CO_2$ removal characteristics were examined by changing influent flow rate of alkaline wastewater (initial pH=10.1) and influent $CO_2$ flow rates. Influent flow rates of alkaline wastewater ($Q_{L,in}$) ranged between 0.9 and 6.6 L/min, and inlet gas flow rate ($Q_{G,in}$) of 1 and 6 L/min in a lab-scale continuous flow jet loop reactor. The outlet pH of wastewater was maintained at 7.2 when the ratio ($Q_{L,in}/Q_{G,in}$) of $Q_{L,in}$ and $Q_{G,in}$ was 1.1. However, the $CO_2$ removal efficiency and the outlet pH of wastewater were increased when $Q_{L,in}/Q_{G,in}$ ratio was higher than 1.1. Throughout the experiments, the maximum $CO_2$ removal efficiency and the outlet pH of wastewater were 98.06% and 8.43 at the condition when $Q_{G,in}$ and $Q_{L,in}$ were 2 L/min and 4 L/min, respectively.

• Journal of Korean Tunnelling and Underground Space Association
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• v.14 no.6
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• pp.617-635
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• 2012

In this study, correlations between the rock mass permeability before and after grouting & injection volume and the parameters of Q system were investigated on a grouted rock mass tunnel corresponding to rock class 4 and 5 in terms of Q classification system. As a result, it appears that the lower the Q value is, the higher the before-grouting permeability becomes and the smaller the injection volume of grouting becomes. Also RQD and Jn are the most influencing factors to the permeability of rock mass and the injection volume of grouting. In addition, it turned out that it was very difficult to lower the permeability of rock mass smaller than $1.0{\times}10^{-8}$ m/sec with the ordinary portland cement grout.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.9 no.6
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• pp.1787-1794
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• 2008

Coenzyme $Q_{10}$ and six derivatives of coenzyme $Q_n$ were synthesized and tested for their antioxidative effects occurred in proximal tubular epithelial cell (LLC-PK1 cell) and cytotoxicities using in NIH/3T3 cell. As the result, synthetic coenzyme $Q_n$ derivatives showed a potent antioxidative effect compared to coenzyme $Q_{10}$. Among these synthetic compounds, coenzyme $Q_3$-C at ranged 0.04 to 0.4 mmol showed the $107.7{\sim}135.9%$ of cell viability in LLC-PK1 cell. In the test of NIH/3T3, all synthesized coenzyme $Q_n$ derivatives showed the similar effect compared with coenzyme $Q_{10}$. A correlation between isoprene unit number of coenzyme $Q_n$ derivatives and its biological effects, we suggest reduction of isoprene unit number of $Q_n$ derivatives may be related to the increase of antioxidants effects and the reduction of cytotoxicities.

• Korean Journal of Agricultural Science
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• v.49 no.4
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• pp.795-807
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• 2022

The development and commercialization of industrial genetically modified (GM) organisms is actively progressing worldwide, highlighting an increased need for improved safety management protocols. We sought to establish an environmental monitoring method, using real-time polymerase chain reaction (PCR) and propidium monoazide (PMA) treatment to develop a quantitative detection protocol for living GM microorganisms. We developed a duplex TaqMan quantitative PCR (qPCR) assay to simultaneously detect the selectable antibiotic gene, ampicillin (AmpR), and the single-copy Escherichia coli taxon-specific gene, D-1-deoxyxylulose 5-phosphate synthase (dxs), using a direct cell suspension culture. We identified viable engineered E. coli cells by performing qPCR on PMA-treated cells. The theoretical cell density (true copy numbers) calculated from mean quantification cycle (Cq) values of PMA-qPCR showed a bias of 7.71% from the colony-forming unit (CFU), which was within ±25% of the acceptance criteria of the European Network of GMO Laboratories (ENGL). PMA-qPCR to detect AmpR and dxs was highly sensitive and was able to detect target genes from a 10,000-fold (10^-4) diluted cell suspension, with a limit of detection at 95% confidence (LOD_95%) of 134 viable E. coli cells. Compared to DNA-based qPCR methods, the cell suspension direct PMA-qPCR analysis provides reliable results and is a quick and accurate method to monitor living GM E. coli cells that can potentially be released into the environment.

• Management & Information Systems Review
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• v.35 no.1
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• pp.117-141
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• 2016

This Research Paper was based on practical method to examine a subjectivity of ODA experts' images. It was used Q-methodology to solve the research problems. I found 4 types of images out throughout the process totally. The perception patterns came out in the research were divided into 4 types in Q-methodology. The results is following ; Those are separated 4 types like Type 1(called operationally individual type), Type 2(arbitrary type), Type 3(mellow type), Type 4(onlooking type). These types consist of each elements to evaluate ODA experts from the people minds. Therefore, This study give us one way to take an assessment of ODA projects. The results reveal that korean ODA policy more has to depend on the scientific evaluation of the person participated in each projects. And the findings demonstrate good questions in comparing with trends of ODA distributors of international development cooperation such as OECD/DAC.