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Exposure Assessment of Total Aflatoxin in Foods (식품중 총 아플라톡신의 노출량 평가)

  • Suh, Jung-Hyuk;Sho, You-Sub;Park, Seong-Soo;Choi, Woo-Jeong;Lee, Jong-Ok;Kim, Hee-Yun;Woo, Gun-Jo;Oh, Keum-Soon
    • Korean Journal of Food Science and Technology
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    • v.39 no.1
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    • pp.25-28
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    • 2007
  • A survey of total aflatoxin levels was conducted on 565 food samples (cereals, nuts, etc) collected in commercial markets. The determination of aflatoxins ($B_{1}$, $B_{2}$, $G_{1}$ and $G_{2}$) was performed using HPLC with fluorescence detector. The Limit of Detections (LODs) of the B group and G group were 0.05 ng/g and 0.07 ng/g, respectively. In addition, recoveries of rice, peanut butter, and red pepper flour were satisfactory. Total aflatoxin was detected 27 samples(4.8%) out of 565 samples. Incidence ratios in cereals, nuts, processed products, and other foods were 0.2, 0.4, 3.0 and 1.2%, respectively, but aflatoxin was not detected in pulse and dried fruits. The daily intake of total aflatoxin using food intakes was 0.04 ng/kg bw/day.

Material Characteristics, Deterioration Evaluation and Crack Depth Estimation for Mulgyeseowon Stele in Changnyeong, Korea (창녕 물계서원 원정비의 재질특성 및 손상도 평가와 균열심도 측정)

  • Yoo, Ji Hyun;Lee, Chan Hee;Chun, Yu Gun
    • Journal of Conservation Science
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    • v.30 no.4
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    • pp.427-438
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    • 2014
  • To measure the depth and extension on the surface cracks of the stone monument, ultrasonic pulse velocity targeted at the Mulgyeseowon Stele in Changnyeong was used in this research. Additionally, to establish a long-term countermeasure of management and conservation for this stele, we have investigated the material properties and damage on it and have conducted a precise diagnosis by a variety of non-destructive techniques. Our research has revealed that stones of the stele are composed mainly of three rock types according to the parts of it, alkali-feldspar granite, gabbro and diorite. The result of the deterioration evaluation has occurred that cracks, which are observed from every direction in the body of the stele, are the significant factors to reduce structural stability. The ultrasonic velocity for an evaluation on the properties of the stele has revealed that the speed was high in the order of body, pedestal and crown. Furthermore, to understand the present condition and occurrences of the cracks which have measured in many different forms on the stele quantitatively, we have estimated from 0.6 to 24.1cm deep of the cracks by To-Tc method using ultrasonic velocity.

A Design of DLL-based Low-Power CDR for 2nd-Generation AiPi+ Application (2세대 AiPi+ 용 DLL 기반 저전력 클록-데이터 복원 회로의 설계)

  • Park, Joon-Sung;Park, Hyung-Gu;Kim, Seong-Geun;Pu, Young-Gun;Lee, Kang-Yoon
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.48 no.4
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    • pp.39-50
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    • 2011
  • In this paper, we presents a CDR circuit for $2^{nd}$-generation AiPi+, one of the Intra-panel Interface. The speed of the proposed clock and data recovery is increased to 1.25 Gbps compared with that of AiPi+. The DLL-based CDR architecture is used to generate the multi-phase clocks. We propose the simple scheme for frequency detector (FD) to mitigate the harmonic-locking and reduce the complexity. In addition, the duty cycle corrector that limits the maximum pulse width is used to avoid the problem of missing clock edges due to the mismatch between rising and falling time of VCDL's delay cells. The proposed CDR is implemented in 0.18 um technology with the supply voltage of 1.8 V. The active die area is $660\;{\mu}m\;{\times}\;250\;{\mu}m$, and supply voltage is 1.8 V. Peak-to-Peak jitter is less than 15 ps and the power consumption of the CDR except input buffer, equalizer, and de-serializer is 5.94 mW.

Severe Nephritic-nephrotic Syndrome with Small Bowel Perforation in a Child with $Henoch-Sch\ddot{o}nlein$ Purpura (신염-신증후군과 소장 천공을 동반한 $Henoch-Sch\ddot{o}nlein$ 자반증 1례)

  • Kim, Gun-Ha;Shin, Hye-Kyung;Yim, Hyung-Eun;Hong, Young-Sook;Lee, Joo-Won;Won, Nam-Hee;Yoo, Kee-Hwan
    • Childhood Kidney Diseases
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    • v.11 no.1
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    • pp.106-111
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    • 2007
  • [ $Henoch-Sch\ddot{o}nlein$ ] Purpura(HSP) is a form of vasculitis that typically affects small arteries in the skin, joints, intestinal tract and kidneys. It usually resolves spontaneously but sometimes can cause serious problems in the kidneys and intestinal tract. A 6-year-old girl with purpura, arthralgia and abdominal pain for 2 weeks was admitted. She also showed gross hematuria, generalized edema and decreased urine output. Blood pressure was in the upper normal range. Initial laboratory findings showed hypoalbuminemia, hyperlipidemia, microhematuria and nephrotic-range proteinuria(27.2 g/day). Initially, she was treated with pulse methylprednisolone, azathioprine, albumin and furosemide. Her renal biopsy revealed diffuse mesangial proliferation with strong IgA deposition. There were no crescents. On the third hospital day, she complained of severe abdominal pain and free peritoneal air was seen on abdominal X-ray. Primary repair of small bowel was performed and two pin-point sized holes were found. One week later, she still showed heavy proteinuria. Therefore, we added an ACE inhibitor and dipyridamole, and changed azathioprine to cyclosporine. One month later, the urine protein/creatinine ratio was decreased to 17.8 from 57, but heavy proteinuria has been still persisted. Here we report a rare case of a patient with HSP who had both severe nephrritc-nephrotic syndrome and small bowel perforation.

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Combined Spa-Exercise Therapy for Vital Sign, Body Composition, Skin Status in Participants of Middle-Aged Women: A Before and After Study (12주간의 온천요법 전후 갱년기 환자의 혈압, 맥박, 체성분, 피부 변화에 관한 임상연구)

  • Kim, Myoung-Kyu;Huh, Gun;Nam, Dae-Jin;Lee, Jae-Eun;Kim, Ki-Hong;Lee, Jung-Min;Oh, Min-Seok
    • Journal of Korean Medicine Rehabilitation
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    • v.25 no.4
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    • pp.123-137
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    • 2015
  • Objectives The aim of this clinical study was to find out the changes of vital sign, body composition, skin status before and after combined spa-exercise therapy in participants of middle-aged women. Methods In this study 24 participants of middle-aged women went through 12 weeks of combined spa-exercise therapy. Each week vital sign, body composition, skin status were measured before exercise, which consisted of warming-up, whole body exercise and final exercises bathing in spa ($32{\sim}36^{\circ}C$). Results 1. The average of systolic blood pressure significantly decreased from $126.38{\pm}19.33mmHg$ to $120.46{\pm}11.18mmHg$ after 11 weeks of spa-exercise therapy (p<0.05). 2. The average of moisture of skin significantly increased from $36.83{\pm}3.18$ to $44.21{\pm}7.43$ after 11 weeks of spa-exercise therapy (p<0.05). 3. The average of elasticity of skin significantly increased from $59.75{\pm}3.50$ to $62.63{\pm}2.29$ after 11 weeks of spa-exercise therapy (p<0.05). 4. The average of diastolic blood pressure, pulse, et cetera. didn't significantly change after spa-exercise therapy. Conclusions The results showed that 12 weeks of spa-exercise therapy had significant effect on reducing systolic blood pressure, increasing moisture, elasticity of skin in participants of middle-aged women, which means spa-exercise therapy may be used as a treatment on high blood pressure and cutaneous diseases. Further studies are anticipated to find out other various effects of spa-exercise therapy.

Assessment of the Application Status of Transcutaneous/Percutaneous Vagus Nerve Stimulation for Musculoskeletal Pain: A Scoping Review for Utilization in Korean Medicine and Subsequent Research (경피적 미주 신경 자극술의 근골격계 통증에 대한 적용 현황 파악: 한의학적 활용 및 후속 연구를 위한 Scoping Review)

  • Gun Hee Bae;Jeong Hoon Ahn;Dong Jin Jang;Jeong Hee Noh;Jae Kwon Shin;Eun Seok Jin;Sun Kyu Yeom;Seung Ju Oh
    • Journal of Korean Medicine Rehabilitation
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    • v.34 no.1
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    • pp.65-81
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    • 2024
  • Objectives This study aimed to understand the general research trends, applicated disease, and methodology of transcutaneous/percutaneous vagus nerve stimulation, contemplating its clinical use in traditional Korean medicine and future research directions. Methods A scoping review was conducted following Arksey and O'Malley Framework Stage and adhering to the PRISMA extension for scoping reviews: checklist and explanation. Papers published until October 30, 2023, were investigated across 10 databases (PubMed, Embase, Scopus, Web of Science, China National Knowledge Infrastructure, Oriental Medicine Advanced Searching Integrated System, Korean Studies Information Service System, KMbase, Science ON, Research Information Sharing Service. The search terms used were 'Transcutaneous/Percutaneous vagus nerve stimulation'. Results Since 2021, the application of transcutaneous/percutaneous vagus nerve stimulation for musculoskeletal symptoms has been actively researched, predominantly in Asia (37%), Europe (37%), and North America (21%). All 19 papers were part of clinical studies. Chronic pain was noted that most applied disease, it also was found to potentially aid in acute post-surgical pain relief. Major assessment tools include not only simple pain metrics but also pain perception, vagal nerve tension, quality of life, and inflammatory markers. Most procedures were carried out through the ear, which offers a favorable site for therapeutic stimulation without notable side effects. And parameter analysis, frequencies typically ranged around 25 Hz to 30 Hz, while pulse widths were commonly set at 250 ㎲ or 300 ㎲. Conclusions Transcutaneous/percutaneous vagus nerve stimulation is easily accessible through acupuncture in Korean medicine. Therefore, if future studies establish parameters and clinical significance, it could be utilized as a therapeutic modality.

Analysis of Groundwater Flow Characterization in Fractured Aquifer System (파쇄대 응회암 대수층의 지하수 유동 특성화 기법)

  • Kim Yong-Je;Kim Tae-Hee;Kim Kue-Young;Hwang Se-Ho;Chae Byung-Gon
    • Journal of Soil and Groundwater Environment
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    • v.10 no.4
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    • pp.33-44
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    • 2005
  • On the basis of a stepwise and careful integration of various field and laboratory methods the analysis of groundwater flow characterization was performed with five boreholes (BH-1, -2, -3, -4, -5) on a pilot site of Natural Forest Park in Guemsan-gun, Chungcheongbook-do, Korea. The regional lineaments of NW-SE are primarily developed on the area, which results in the development of many fractures of NW-SE direction around boreholes made in the test site for the study. A series of surface geological survey, core logging, geophysical logging, tomography, tracer tests, and heat-pulse flowmeter logging were carried out to determine fracture characteristics and fracture connectivity between the boreholes. In the result of fracture connectivity analysis BH-1 the injection well has a poor connectivity with BH-2 and BH-3, whereas a good with BH-4 and BH-5. In order to analyse the hydraulic connectivity between BH-1 and BH-5, in particular, a conspicuous groundwater outflux in the depth of 12 m and influx in the depth of 65 m and 70 m, but partly in/outflux occurred in other depths in BH-5 were observed as pumping from BH-1. On the other hand, when pumping from BH-5 the strong outflux in the depths of 17 m and 70 m was occurred. The spatial connectivity between the boreholes was examined in the depth of 15 m, 67 m, and 71 m in BH-1 as well as in the depth of 15 m, 17 m, 22 m, 72 m, and 83 m in BH-5.