• Title/Summary/Keyword: Pt-Pd

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The Study of Hepatic Antioxidative Enzyme Activity and Eletrophoresis in Mice After Treatment with Paraquat and/(or) Ginseng Saponins (Paraquat를 투여한 생쥐 간에서 홍삼 사포닌의 항상화 효소 활성과 전기영동에 관한 연구)

  • Chun, Chul;Kim, Dong-Jo;Sung, Kum-Soo;Kim, Jong-Hwan;Kim, Ji-Sik;Chang, Che-chul
    • Journal of Ginseng Research
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    • v.25 no.4
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    • pp.150-155
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    • 2001
  • This study examined effects of the active ingredients from ginseng on paraquat(PQ) toxitity. Mice were given PQ(25mg/kg, ip) and then they were given total saponins (TS; 5mg/kg, orally), protopanaxadiol (PD; 5mg/kg, orally) and protopanaxatriol(PT; 5mg/kg, orally) per day for periods of 1,3 & 7 days. We measured the activities of superoxide dismutase (SOD), electrophoretic isozyme band, catalase (CAT) were compared in the liver of mouse that dose with PQ and/or TS, PD and PT. The activities of SOD, CAT were generally higher in PQ+PD group than others groups. Especially the activity of SOD was the highest in PQ+PD group than others groups. SOD isozyme separated into three bands by electrophoresis. One band was located to near the anode side and two bands were cathode side. As the results of treated with KCN, we were confiremed that the Cu, Zn-SOD was located to near the anode side but the Mn-SOD were cathode side. Our results suggested that an antioxidant effect of ginseng saponins elevated a protection ability to an oxidative damage by direct action of SOD, CAT and reinforced the synthetic ability of endogenous antioxidant material in living organism. Particularly, PD was a effective antioxidant compared with others.

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Underlayer for Coercivity Enhancement of Ti/CoCrPt Thin Films (보자력 향상을 위한 Ti/CoCrPt박막의 하지층)

  • Jang, Pyung-Woo
    • Journal of the Korean Magnetics Society
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    • v.12 no.3
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    • pp.94-98
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    • 2002
  • Sputtering conditions and various underlayer such as Al, Cu, Ni, Cr, Ag, Mg, Fe, Co, Pd, Au, Pt, Mo and Hf were investigated for coercivity enhancement of 20 nm Ti/CoCrPt thin films in order to increase the coercivity of the films thinner than 20 nm. Among them, Ag and Mg were effective to increase the coercivity. Particularly 2 nm Ag was very effective to increase the coercivity and nucleation field as well as to reduce ${\alpha}$ value in CoCrPt thin film such that the coercivity of 2 nm Ag/18 nm Ti/10 nm CoCrPt film was 2200 Oe. However, it seemed that other coercivity enhancement mechanism operated in CoCrPt films because Ti (002) preferred texture was not developed with Ag underlayer contrary to a general expectation. And the coercivity and nucleation field were decreased when glass substrate with rougher surface was used.

Improvement on Property of Insulation in PT of Epoxy Mold Type (에폭시 몰드형 PT의 절연특성 개선)

  • Song, Jae-Joo;Kim, Sung-Hong;Choi, Myeong-Ho;Lee, Jae;Lim, Sung-Hun;Han, Byung-Sung
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2001.09a
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    • pp.67-71
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    • 2001
  • PT of epoxy mold type have tendency to occur dielectric breakdown in high voltage system. These are using for measurement of voltage or protection of system and application voltage is 25.8kV. Therefore, for improving a lots of problems like as partial discharge, we had analyze on the destroyed Epoxy molded type PT and processing of production. As a results, we concluded that the reason of dielectric breakdown was defect of processing and degradation of insulation by electrical stress. In this work, We presented a method of solution in processing of production. which is reduction of the PO which was occurred at the insulation material. so we must many try to remove faults, these problems are mainly to winding methods of 1st coil. the other side, Reformation of 1st coil improved property of PD and we could prove it with experiments.

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Research of UHF PD measuring techniques for Oil-Transformer (Oil-Transformer에서의 UHF PD 측정 기술 연구)

  • Lee, C.J.;Kang, W.J.;Kang, Y.S.;Park, J.B.;Lee, H.C.;Park, J.W.
    • Proceedings of the KIEE Conference
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    • 2003.07c
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    • pp.1809-1811
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    • 2003
  • Oil-TR에서의 이상을 진단하기 위해서, 유중가스 분석 및 AE센서를 사용한 부분방전측정을 중심으로 많은 연구가 진행/적용되어왔다. 근래 들어서는 거의 모든 진단항목이 환선상태에서 측정하는 것으로 전이되는 추세이며, 사용자가 설비의 현재의 상태를 계속 감시하여 수명을 연장시키는데 관심의 초점이 모아지고 있다. 이에 본 논문에서는 Spiral-Type의 광대역 UHF센서를 사용하여 TR에서 발생하는 부분방전을 측정하였다. 이 방식은 TR내부에 센서를 주입하는 방식으로서, 상대적으로 감도가 우수하며, 노이즈의 영향이 적게 받는다. 코로나방전, 표면방전 및 부유물 형태의 결함에 대하여 측정한 결과를 나타내었으며, 주파수 분포에 대한 변화를 주로 관측하였다. 결과적으로, 서로 다른 결함은 서로 다른 결과를 나타내었으며, 이를 바탕으로 Oil-TR에서 발생하는 결함을 인식할 수 있는 데이터로 활용할 수 있다.

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Synthesis of Some Palladium (II) Complexes of 1, 2-Diaminocyclohexane and Dicarboxylates as Cisplatin Analogues of Palladium Series

  • Kim, Jong-Yoon
    • Archives of Pharmacal Research
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    • v.15 no.4
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    • pp.336-342
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    • 1992
  • Ten [$Pd^{II}$(dicarboxylato)(1, 2-diaminocyclohexane)] complexes were prepared after the antitumor-active Pt(II)1, 2-diaminocyclohexane complexes as the cisplatin analogues of palladium series. They were characterized by means of elemental analysis, IR and NMR spectroscopy. As a result, the dicarboxylate ligands were conformed to be chelated with Pd(II) within the scope studied. The stability differences beween the dicarboxylato complexes according to the chelate ring size could not be differentiated due to generally lower thermodynamic stability of the dicarboxylato Pd(II) complexes.

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Development of a Semiconductor Odor Gas Sensor for the Measurement of CH3SH with Taguchi Experimental Design (Taguchi 실험 계획법에 의한 CH3SH 반도체 악취 가스 센서의 개발)

  • Kim Sun-Tae;Choi Il-Hwan
    • Journal of Korean Society for Atmospheric Environment
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    • v.20 no.6
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    • pp.783-792
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    • 2004
  • In this study, a thick-film semiconductor odor gas sensor for the detection of $CH_3$SH was developed using SnO$_2$ as the main substrate and was investigated in terms of its sensitivity and reaction time. In the process of manufacturing the sensor, Taguchi's design of experiment (DOE) was applied to analyze the effects of a variety of parameters, including the substrate, the additives and the fabrication conditions, systematically and effectively. Eight trials of experiments could be possible using the 27 orthogonal array for the seven factors and two levels of condition, which originally demands 128 trials of experiments without DOE. The additives of Sb$_2$O$_{5}$ and PdCl$_2$ with the H$_2$PtCl$_{6}$ ㆍ6$H_2O$ catalyst were appeared to be important factors to improve the sensitivity, and CuO, TiO$_2$, V$_2$O$_{5}$ and PdO were less important. In addition, TiO$_2$, V$_2$O$_{5}$ and PdO would improve the reaction time of a sensor, and CuO, Sb$_2$O$_{5}$, PdCl$_2$ and H$_2$PtCl$_{6}$ㆍ6$H_2O$ were negligible. Being evaluated simultaneously in terms of both sensitivity and reaction time, the sensor showed the higher performance with the addition of TiO$_2$ and PdO, but the opposite results with the addition of CuO, V$_2$O$_{5}$, Sb$_2$O$_{5}$ and PdCl$_2$. The amount of additives were superior in the case of 1% than 4%. H$_2$PtCl$_{6}$ㆍ6$H_2O$ would play an important role for the increase of sensor performance as a catalyst.nce as a catalyst.

Effects of the Antioxidative Components to Ginsenoside in the Liver of 40-week-old Mice (40주령의 생쥐 간에 미치는 ginsenoside의 항산화효과)

  • 김경현;성금수;장재철
    • Journal of Ginseng Research
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    • v.24 no.4
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    • pp.162-167
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    • 2000
  • To study on antioxidant effects of saponin fractions, we investigated effects in the liver of 40-week-old mice to which were pretreated with 5 mg/kg per body weight of saponins for 5 days. The ability of saponins to protect against oxidative damage to the mouse liver was examined by determining the level malondialdehyde (MDA),hydrogen peroxide and the activity of superoxide dismutase (SOD) and catalase (CAT). The only panaxadiol (PD)among the ginseng saponin fractions significantly increased the hepatic SOD activities (p<0.01), Whereas PD, panaxatriol (PT), ginsenoside Rd (G-Rd) (p<0.01) and ginsenoside Re (G-Re) (p<0.05) significantly decreased the contents of hydrogen peroxide. It was only G-Rd that significantly increased CAT activities (p<0.05). The level of MDA was significantly decreased by G-Rd and PD. In conclusion, PD and G-Rd among the saponin fractions were especially increased in the activity of hepatic antioxidative enzyme and decreased the lipid peroxidation that was expressed in term of MDA formation.

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