• 약학회지
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• 제58권5호
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• pp.300-306
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• 2014

Ethanol consumption causes psychomotor alterations. Hovenia Semen seu Fructus (HS), widely distributed in Korea, China, and Japan, has been reported to have beneficial effects on acute alcohol-induced liver injury. The present study sought to assess the effects of HS extract on ethanol-induced psychomotor alterations in rats. Sprague-Dawley rats were orally (p.o.) given ethanol (4 g/kg) (ethanol group) to induce psychomotor alterations. A separate group (HS-treated groups), were treated with different dosages of HS (50, 100, and 200 mg/kg, p.o.), 30 minutes before ethanol treatment. The control group received only the vehicle (saline). Ethanol-induced psychomotor alterations were evaluated in the open-field, rota-rod, hanging wire, and cold swimming test. In addition, blood ethanol and acetaldehyde concentrations were also measured. Behavioral evaluations and blood analysis were carried out 0.5, 1, 2, 4, and 8 hours after ethanol administration. Pre-treatment of HS ameliorated ethanol-induced alterations in the open-field, rota-rod, and cold swimming test, significantly evident in 2 and 4 hours after ethanol treatment. These improvements coincided with decrease in blood ethanol and acetaldehyde concentration. Based on these results, the present study suggests that HS may have ameliorating effects against ethanol-induced psychomotor alterations.

• 사물인터넷융복합논문지
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• 제6권1호
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• pp.55-63
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• 2020

본 논문은 심리운동프로그램이 보육교사의 자아탄력성과 보육효능감에 미치는 영향을 확인하기 위해 시도되었다. 본 연구의 대상자는 서울시 J구의 8개 어린이집의 보육교사로서 최종 대상자는 실험군 18명, 대조군 19명 이었다. 중재프로그램으로 1회 4시간, 주 2회, 총 10회, 총 40시간의 심리운동프로그램을 보육교사에게 제공하였다. 자료수집은 2017년 9월 2일부터 11월 12일 사이에 이루어졌으며 수집된 자료는 독립표본 Wilcoxon-Mann-Whitney test로 분석하였다. 연구결과는 심리운동프로그램이 보육교사의 자아탄력성과 하위요인인 대인관계 효율성 향상에 유의한 효과가 있음을 보여주었으며 이를 통해 보육교사의 자아탄력성 관리와 지원을 위한 기초근거를 마련의 가치가 있었음을 확인하였다. 본 연구는 보육교사의 직무에서의 적응과 대처능력 향상에 도움이 될 수 있는 방안을 제시하였으므로 그의미와 가치가 있다고 판단된다.

• Journal of Ginseng Research
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• 제41권2호
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• pp.201-208
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• 2017

Background: Panax vietnamensis Ha et Grushv. or Vietnamese ginseng (VG) is a recently discovered ginseng species. Studies on its chemical constituents have shown that VG is remarkably rich in ginseng saponins, particularly ocotillol saponins. However, the psychopharmacological effects of VG have not been characterized. Thus, in the present study we screened the psychopharmacological activities of VG in mice. Methods: VG extract (VGE) was orally administered to mice at various dosages to evaluate its psychomotor (open-field and rota-rod tests), sedative-hypnotic (pentobarbital-induced sleeping test), anti-stress (cold swimming test), anxiolytic (elevated plus-maze test), and cognitive (Y-maze and passive-avoidance tests) effects. Results: VGE treatment increased the spontaneous locomotor activity, enhanced the endurance to stress, reduced the anxiety-like behavior, and ameliorated the scopolamine-induced memory impairments in mice. In addition, VGE treatment did not alter the motor balance and coordination of mice and did not potentiate pentobarbital-induced sleep, indicating that VGE has no sedative-hypnotic effects. The effects of VGE were comparable to those of the Korean Red Ginseng extract. Conclusion: VG, like other ginseng products, has significant and potentially useful psychopharmacological effects. This includes, but is not limited to, psychomotor stimulation, anxiolytic, antistress, and memory enhancing effects.

• 대한교통학회지
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• 제30권6호
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• pp.27-36
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• 2012

국내 2010년도 음주운전 교통사고는 28,641건으로 전체 사고건수 226,878건의 12.62%를 차지하고 있지만, 사망자수는 781명, 부상자수는 51,364명으로 전체 교통사고 사망자수인 5,505명의 14.19%, 부상자수인 352,458명의 14.57%로 여전히 높은 비율을 차지하고 있다. 음주운전으로 인한 교통사고를 예방하기 위해서 경찰 단속이나 법적규제를 강화하는 등 다양한 노력을 기하고 있지만 음주운전에 대한 사회문화적 관용과 상습음주운전자 관리 부재등으로 인하여 음주 관련 교통사고가 쉽게 줄어들지 않고 있는 것이 현실이다. 본 연구에서는 음주운전의 특성 및 음주에 따른 운전행동 변화를 실증적으로 알아보기 위하여 정신운동검사와 차량시뮬레이터를 활용하여 국내운전자 26명을 대상으로 음주 전 후 정신운동 및 운전 수행 결과를 비교분석 하였다. 정신운동검사 결과의 경우, 음주 후에는 음주 전에 비하여 정답수가 감소하고 오답수는 증가하였으며 생략반응 또한 증가되는 경향을 나타냈다. 그리고 차량시뮬레이터 실험결과에서는 음주 전에 비하여 음주 후의 주행속도가 상대적으로 빨라졌으며 가속페달 답력 편차 및 차량편측위치 편차가 커지는 등 위험운전 행태를 보였다. 이러한 결과는 알코올이 운전자의 시각인지능력 및 주행안전성을 저하시킨다는 것을 보여준다. 마지막으로 본 연구의 제한점 및 향후 연구방향을 제시하였다.

• 한국융합학회논문지
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• 제9권7호
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• pp.301-308
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• 2018

본 연구는 장애노인 신체활동 프로그램의 구성 유형을 분석하고 효과에 대한 메타분석을 실시하였다. 검색된 전체 177편의 연구 중 본 연구를 위해 선별과정과 필수적인 요소를 갖춘 총 14편의 연구가 선정되었지만, 한 연구 안에 신체활동 효과의 범주가 중복된 경우 개별 연구로 가정하여 총 28개의 효과 크기를 계산하였다. 메타분석을 위해 선행연구들의 효과 크기와 출간오류 등을 분석하였으며, Hedges'g, funnel plot, forest plot, Egger's regression test, trim-and-fill, fail-safe N 등을 수행하였다. 그 결과 첫째, 장애노인에게 신체활동은 효과적이고 심동적, 인지적, 정의적 영역에 좋은 효과가 나타났다. 둘째, 기본운동기술, 게임 및 스포츠, 체력운동의 신체활동 프로그램은 장애노인의 심동적, 인지적, 정의적 영역에 좋은 효과가 나타났다. 셋째, 장애노인의 심동적 영역은 기본운동기술 프로그램이 가장 효과가 높았으며, 인지적 영역은 게임 및 스포츠, 정의적 영역은 체력운동 프로그램이 가장 효과가 높은 것으로 나타났다.

• 고려인삼학회:학술대회논문집
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• 고려인삼학회 1974년도 학술대회지
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• pp.65-67
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• 1974

In a double-blind test performed for 33-days on healthy students 2 capsules daily of Geriatric Pharmaton (ginsengextractvitamins and diethylaminoethanol) and of Gerikomplex Vitamex (ginsengextract viatmins but no diethylaminoethanol) showed a significant positive effect on psychomotor activity and simultaneous capacity. With the two methods used no difference between the prerarations could be demonstrated.

• 대한한의학회지
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• 제42권3호
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• pp.86-98
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• 2021

Objectives: This study aims to evaluate the impact of patient-physician communication curriculum on students of Korean medical school in terms of cognitive, affective, and psychomotor level of communication skills. Methods: A communication curriculum was developed considering COVID-19 pandemic situation. Lectures, peer role-play, open interview with standardized patient (SP), discussion and feedback were conducted by online, and face-to-face 1:1 SP-interview was performed. Scores of written test, peer role-play of medical communication, SP-interview, self-evaluation on one's interview with real patients in clinical clerkship, and questionnaire of importance were collected and analyzed. Results: Converted to 100 point scale, the mean score of written test (cognitive level) was 91.2 while that of importance questionnaire (affective level) was 77.5. The mean scores of psychomotor level were 72.5, 77.5, and 62.5 for peer role-play, SP-interview, and real patient interview in clerkship, respectively. Conclusions: Students' performance is lower in higher level of competence. Curriculums should provide more opportunities of practices to students, and include evaluation focusing on performance skills.

• Investigative Magnetic Resonance Imaging
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• 제24권1호
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• pp.30-37
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• 2020

Purpose: Preterm infants are at high risk for adverse neurodevelopmental outcomes. Magnetic resonance imaging (MRI) has been proposed as a means of predicting neurodevelopmental outcomes in this population. It is controversial whether diffuse excessive high signal intensity (DEHSI) represents damage to the white matter or delayed myelination in preterm infants. This study investigated MRI findings for predicting the severity of neurodevelopmental outcomes and assessing whether preterm infants with DEHSI near term-equivalent age have abnormal neurodevelopmental outcomes. Materials and Methods: Preterm infants (n = 64, gestational age at birth < 35 weeks) undergoing brain MRI near term-equivalent age and subsequent neurodevelopmental outcomes were evaluated between 18 and 24 months of age. The associations of MRI findings and the risk of severe cognitive delay, severe psychomotor delay, cerebral palsy (CP), and neurosensory impairment were analyzed. The associations of DEHSI with risks of severe cognitive delay, severe psychomotor delay, CP, and neurosensory impairment (hearing or visual impairment) were analyzed. Outcome data were evaluated by logistic regression and the Fisher's exact test. Results: There were significant associations between abnormal white matter findings and delayed mental development, delayed psychomotor development, neurosensory impairment, and presence of CP. The presence of DEHSI was not correlated with delayed neurodevelopmental outcomes or presence of CP. In multivariate logistic regression analyses, cystic encephalomalacia, punctate lesion, loss of white matter volume and ventricular dilation were significantly associated with CP. Conclusion: Abnormal MRI findings near term-equivalent age in preterm infants predict adverse neurodevelopmental outcomes. No significant association between DEHSI and adverse neurodevelopmental outcomes was demonstrated.

• 생물정신의학
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• 제3권2호
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• pp.222-239
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• 1996

ALDH-I 활성군과 비활성군에서 음주후 정신운동성 수행 및 주관적 평가에 미치는 영향을 비교하였다. 사교적 음주에 상응하는 4종류의 알콜(0.25, 0.5, 0.75, 1.0g/kg)을 투여한 결과 비활성군이 활성군에 비해 보다 부정적인 평가를 하였다. 이는 특히 고용량의 알콜(0.75 및 1.0g/kg)을 투여시 분명하였다. 이러한 결과는 비활성군이 활성군에 비해 알콜에 대한 민감성이 주관적인 판단과 객관적인 수행에서 모두 더 높다는 사실을 반영한다.

• 대한간호
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• 제33권3호
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• pp.56-69
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• 1994

This study was done to develop self - directed learning modules related to asepsis and elimination including urine and stool for Fundamentals in Nursing practice education contents and to measure the effectiveness of those modules. The subjects of this study were 96 sophomore students in the nursing college. Self-directed learning modules were developed by the researcher on the basis of the Lippincott Learning System of Kruger (1986) and Modules for Basic Nursing Care of Ellis (1992). Videotape was editted by using videotape made by the Lippincott Company and Film strip made by the Trainex Company with Korean dubbing. Self-directed learning was done for one week with the asepsis module and two weeks with the elimination modules after confirming the requiered level of knowledge acquisition through pre-test. For measuring proficiency in self-directed learning, a written test for cognitive domain, a sufficiency test for psychomotor domain, and a confidnece examination for affective domain were given. The data were analyzed using descritive statistics, and Pearson correlation coefficient using a SPSS-PC program. The results are summarized as follows: 1. Sufficiency test and confidence examination grades showed high levels in both asepsis and elimination. 2. Written test grades showed a high level in asepsis and elimination of urine but showed a medium level in eliminationin of stool. 3. Grades of sufficiency and confidence in asepsis and elimination practice were statistically significant with a moderate positive correlation (r=0.4- 0.5, p<0.001). 4. Grades of sufficiency and written tests in asepsis and elimination practice also were statistically significant with a moderate positive correlation (r=0.5-0.7, p<0.001). 5. Students showed relatively high contentment with the self-directed learning modules themselves but revealed relatively low contentment with video program and the self-directed learning process. In conclusion, this study disclosed that proficiency levels in cognitive, affective, and psychomotor domains were high when asepsis and elimination modules were applied. Also students showed high satisfaction with the modules themselves, but didn't show high contentment with the video programs. In considering low contentment with the self-directed learning process, it is estimated the students had experienced some difficulties about using self-directed learning modules because this was their first exposure to the self-directed learning module and they were already accustomed to the demonstration-practice method.