• Radiation Oncology Journal
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• 제11권2호
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• pp.205-217
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• 1993

In order to evalute the effects of radiation on mammalian neuronal system, we have examined the effect of gamma-ray radiation on the monoamine oxidase (MAO) activity in monoaminergic neurons. Following the whole body irradiation, MAO activity in the rat brain was measured as well as in the liver for the comparative studies between the neuronal and nonneuronal system. The effects of some radiation protectors and sensitizers were also examined in addition to the $O_2$ effect. The results can be summarized as follows. 1) The MAO activity of rat brain was minimally affected by the radiation dose up to 1,700 cGy Radiation dose above 2,500 cGy inhibited the brain MAO activity by no less than $l0\%.$ MAO-A form was found to be particularly sensitive to radiation. The liver MAO was somewhat inhibited (by about $5\%$) but hardly dependent on the dose of radiation. 2) The inhibitory effect on the brain was initiated immediately by the radiation dose of 2,500 cGy. On the contrary, for the liver, the inhibitory effect became apparent only 2 days after irradiation. 3) Two days after a dose of 2,500 cGy, Vmax and Km of the brain mitochondrial MAO decreased. For liver, Vmax decreased while Km increased, which indicates the kinetic patterns for the neuronal and nonneruronal systems are not affected similarly by radiation. 4) The effect of several known radiation protectors and sensitizers on MAO activity was tested ut no definite results were obtained. The level of -SH group increased in some degree upon radiation but not by the compounds. 5) MAO activity was not affected by $O_2$ concentration, while an elevated level of lipid peroxidase was found under the same condition. The results described here indicate that characteristics of MAO, one of the most important central nervous system enzymes, are liable to radiation, which is partially differentiated from the liver MAO. Also indicated are that the -SH groups are hardly related to the effect of radiation but the production of the lipid peroxide seems to be somewhat correlated to the effect of radiation.

• 해양환경안전학회지
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• 제23권2호
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• pp.194-199
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• 2017

오탁방지막이 바닷물 속에 설치되어 있을 때 조류와 파도가 변할 때 움직임과 앵커 파주력을 초과하는 유체력이 작용할 경우의 이동 메카니즘을 질량-스프링법으로 해석하였다. 설치 위치는 전남 진도군 임회면 굴포리 동령개 포구 해역이다. 앵커의 파주력을 초과하는 장력은 0.05 m/s에서는 318초 후에 도달하였고, 0.15 m/s에서는 77초, 0.25 m/s에서는 43초, 0.3 m/s에서는 37초 후에 앵커가 움직이기 시작하여, 조류 속도가 0.01 m/s로 증가함에 따라서 평균 11.2 초 정도, 앵커 이동시작 시간이 단축되고 있었다. 조류만 작용할 때와 파랑이 추가될 때의 차이점은 유속이 느릴 경우, 앵커의 이동이 시작되는 시간의 차이가 7.6 % 정도 발생하였으나, 유속이 빠른 경우는 4.3 % 미만으로 큰 차이가 없이 앵커 이동이 시작되는 것을 알 수 있었다. 조류 속도가 0.13 m/s를 초과하고 파도의 방향이 일치하면 주변의 해저 구조물과의 충돌로 인해 오탁방지막 성능이 정상적으로 작동하지 않을 수 있으니, 오탁방지막을 바다에 설치할 때 해수의 흐름 상황 등을 질량-스프링 방법으로 면밀하게 검토해야 한다.

• 한국의류학회지
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• 제44권4호
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• pp.739-748
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• 2020

In this study, a wrist protector was manufactured and designed using 3D printing technology to prevent wrist pain when riding a bicycle with a high forward-tilted saddle. The efficiency of the design was analyzed in objective and subjective evaluations. First, seven women in their twenties selected their most preferred design by subjective evaluation from among three 3D wrist protectors. Then electromyography (EMG) was measured and subjective sensations were evaluated while wearing and not wearing the preferred 3D wrist protector as selected by cyclists. Experimental results showed that a wrist-bending angle of 30 degrees was most favored. When the 3D wrist protector was worn, muscle activity was smaller at the flexor carpus radialis position than when the 3D wrist protector was not worn; muscle fatigue was also lower. In the subjective evaluation, the 3D wrist protector was more comfortable than no protector, and wrist fatigue was also lower. In addition, the wrist protector was rated positively for its design suitability, size adequacy, ease of operation, and fit; however, cyclists felt that a little more cushioning was needed.

• 패션비즈니스
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• 제13권1호
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• pp.141-151
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• 2009

The purpose of this study consist in the investigation into the pants wearing practices and preference with arthritis patient of aged female and the gathering of basic data to help to their clothing lifestyle. For this study, personal interviews were carried out with 124 arthritis patients of aged female over 65 year old and data analysis were done with SPSS. The results of the study are that on pants wearing practices with the subjects of aged female arthritis patient showed that many persons experience inconvenience for both knees and the wearing of knee protectors which use a purpose of a reducing pain such as they feel inconvenience of knee showed a high rate of 79.8% during winter. They purchased the pants with much space in the knee part or span trousers in consideration of knee protector wearing. When they purchase the pants, they attached great importance to the convenience or activities during their wearing period, prices, and the pants which were wide at the thigh, narrow at the pants hole, hanging down to the anklebones, and setting over the waistline as for the pants' waist position. The arthritis patients who felt uncomfortable at knees paid attention to the excellent materials at keeping warmth and with good flexibility.

• 조명전기설비학회논문지
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• 제24권1호
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• pp.71-77
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• 2010

뇌서지 보호는 오늘날 대부분의 전기전자기기에 있어 중요한 문제 중 하나이다. 그리고 뇌서지 보호를 위한 대다수 SPD의 가장 주요 부품으로 MOV가 사용된다. 본 논문에서는 다양한 타입의 MOV 기반 SPD를 조사하고 낮은 MLV특성의 부작용에 대하여 실험하였다. 실험결과로서 상대적으로 낮은 MLV특성은 실제 현장에서 발생 가능한 TOV 고장 상태하에서 더 큰 고장률로 나타날 수 있으며, 피보호기기보다 우선하여 소손될 수 있음을 알 수 있다. 결국 안전면에서 SPD는 높은 TOV내력과 신속한 단로기의 동작이 요구된다.

• 한국의료질향상학회지
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• 제6권1_2호
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• pp.120-134
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• 1999

Background : This study was conducted to reduce the neonatal infection rate in nursery. Methods : 50 items, structural problems in NICU were selected by open questionnaire and categorized into 11 similar items. 38 items were picked out among them and then categorized into 6 similar items. We carried out quality improvement focusing around 6 items. Results : The high achievement of goal in CQI Activities was shown in hand washing for reducing infection of NICU after July. The local infection in IV site was not found and hand washing and gowning of protectors were achieved by 100%. Conclusion : Neonatal infection rate was reduced through the quality improvement activities, but structural problem of Hospital still remained.

• Journal of Korean Neurosurgical Society
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• 제49권1호
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• pp.37-42
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• 2011

Objective: The author measured levels of fluoroscopic radiation exposure to the surgeon's body based on the different beam directions during kyphoplasty. Methods: This is an observational study. A series of 84 patients (96 vertebral bodies) were treated with kyphoplasty over one year. The patients were divided into four groups based on the horizontal and vertical directions of the X-Ray beams. We measured radiation exposure with the seven dosimetry badges which were worn by the surgeon in each group (total of 28 badges). Twenty-four procedures were measured in each group. Cumulative dose and dose rates were compared between groups. Results: Fluoroscopic radiation is received by the operator in real-time for approximately 50% (half) of the operation time. Thyroid protectors and lead aprons can block radiation almost completely. The largest dose was received in the chest irrespective of beam directions. The lowest level of radiation were received when X-ray tube was away from the surgeon and beneath the bed (dose rate of head, neck, chest, abdomen and knee: 0.2986, 0.2828, 0.9711, 0.8977, 0.8168 mSv, respectively). The radiation differences between each group were approximately 2.7-10 folds. Conclusion: When fluoroscopic guided-KP is performed, the X-Ray tube should be positioned on the opposite side of the operator and below the table, otherwise the received radiation to the surgeon's body would be 2.7-10 times higher than such condition.

• 한국조명전기설비학회:학술대회논문집
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• 한국조명전기설비학회 2007년도 춘계학술대회 논문집
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• pp.250-253
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• 2007

Gas Discharge Tubes (GDTs) are widely used as surge protectors for commnuication applications due to their small internal capacitance. In these days, however, they are mostly used in combined configurations, because the activation voltage required to initiate the discharge process in the GDTs for sufficient amount of time can be large enough to damage surge-sensitive protected circuits. For GDTs with a considerably high initial over-voltage value, we should limit the peak voltage using a TVS or filter. As for ZnO varistors, even though their performance for voltage restriction is excellent, their applications in high-frequency commnuication circuits have been limited because of higher internal capacitance when compared to the GDTs. In order to develop a surge protector for commnuication applications by taking advantages of these two devices, we built a combination circuit that connects a GDT and a ZnO varistor along with a choke coil in common and differential modes. We describe how the applied SPDs operate in protection process steps with the actual data obtained from the residual voltage measurements at each step. The experiment results show that the surge voltage restriction with the choke coil is more effective in 100 [kHz] RingWave voltage than in lightning impulse voltage.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2002년도 하계학술대회 논문집 Vol.3 No.2
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• pp.731-734
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• 2002

This paper describes on the fabrication and characteristics of a ceramic thin-film pressure sensor based on Ta-N strain gauges for harsh environment applications. The Ta-N thin-film strain gauges are sputter deposited onto a micromachined Si diaphragms with buried cavity for overpressure protectors. The proposed device takes advantages of the good mechanical properties of single crystalline Si as diaphragms fabricated by SDB and electrochemical etch-stop technology, and in order to extend the operating temperature range, it incorporates relatively the high resistance, stability and gauge factor of Ta-N thin-films. The fabricated pressure sensor presents a low temperature coefficient of resistance, high sensitivity, low non-linearity and excellent temperature stability. The sensitivity is $1.097{\sim}1.21mV/V{\cdot}kgf/cm^2$ in the temperature range of $25{\sim}200^{\circ}C$ and the maximum non-linearity is 0.43 %FS.

• Radiation Oncology Journal
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• 제32권3호
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• pp.103-115
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• 2014

To summarize current knowledge regarding mechanisms of radiation-induced normal tissue injury and medical countermeasures available to reduce its severity. Advances in radiation delivery using megavoltage and intensity-modulated radiation therapy have permitted delivery of higher doses of radiation to well-defined tumor target tissues. Injury to critical normal tissues and organs, however, poses substantial risks in the curative treatment of cancers, especially when radiation is administered in combination with chemotherapy. The principal pathogenesis is initiated by depletion of tissue stem cells and progenitor cells and damage to vascular endothelial microvessels. Emerging concepts of radiation-induced normal tissue toxicity suggest that the recovery and repopulation of stromal stem cells remain chronically impaired by long-lived free radicals, reactive oxygen species, and pro-inflammatory cytokines/chemokines resulting in progressive damage after radiation exposure. Better understanding the mechanisms mediating interactions among excessive generation of reactive oxygen species, production of pro-inflammatory cytokines and activated macrophages, and role of bone marrow-derived progenitor and stem cells may provide novel insight on the pathogenesis of radiation-induced injury of tissues. Further understanding the molecular signaling pathways of cytokines and chemokines would reveal novel targets for protecting or mitigating radiation injury of tissues and organs.