• Nutrition Research and Practice
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• v.4 no.3
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• pp.183-190
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• 2010

Blueberry was enzymatically hydrolyzed using selected commercial food grade carbohydrases (AMG, Celluclast, Termamyl, Ultraflo and Viscozyme) and proteases (Alcalase, Flavourzyme, Kojizyme, Neutrase and Protamex) to obtain water soluble compounds, and their protective effect was investigated against $H_2O_2$-induced damage in Chinese hamster lung fibroblast cell line (V79-4) via various published methods. Both AMG and Alcalase hydrolysates showed higher total phenolic content as well as higher cell viability and ROS scavenging activities, and hence, selected for further antioxidant assays. Both AMG and Alcalase hydrolysates also showed higher protective effects against lipid peroxidation, DNA damage and apoptotic body formation in a dose-dependent fashion. Thus, the results indicated that water soluble compounds obtained by enzymatic hydrolysis of blueberry possess good antioxidant activity against $H_2O_2$-induced cell damage in vitro.

• Toxicological Research
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• v.3 no.2
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• pp.121-128
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• 1987

Protective effect of scoparone against the acetaminophen inducible hepatic toxicity in mice was investigated. Scoparone (5mg/kg) was administered intraperitoneally to mice daily for 5 days. Scoparone pretreatment before the administration of acetaminophen has blocked subsequent increases in liver to body weight ratio. When biological changes were measured, scoparone protects against acetaminophen inducible hepatotoxicity in mice as evidenced by the decreased formation of lipid peroxide, lowered serum transaminase activity and the decreased level of serum acetaminophen. In conjuction with the results of Huh (Arch. Pharm. Res. 10, 165(1987)), these results suggest that the most likely mechanism for the observed protective effects of scoparone against the acetaminophen-induced hepatotoxicity is the induction of hepatic microsomal UDP-glucuronyltransferase activity.

• Toxicological Research
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• v.20 no.1
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• pp.63-69
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• 2004

Casapse-3 protease is known as a key role of apoptotic enzyme, and caspase-3 activity is a central event that occurs upstream of DNA fragmentation during apoptosis. This study demonstrates that chitosan pretreatment inhibits cadmium-induced apoptosis by attenuating the activity of caspase-3. We also analyzed the protective effect of chitosan on DNA fragmentation induced by cadmium. Cadmium toxicity was examined by DNA fragmentation and nuclear condensation with Hoechst stain. Caspase-3 activities were increased cadmium treated group for 3 hours compared with control. When chitosan (150 mg/ml) was pretreated at 30 min before cadmium treatment, cadmium cytotoxicity was suppressed in a dose-dependent manner evaluated by DNA fragmentation and caspase activity. From these results, it is suggest that the protective effect of chitosan pretreatment against cadmium-induced cytotoxicity is mediated through inhibition of caspase-3 protease activation and DNA fragmentation.

• Korean Journal of Human Ecology
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• v.18 no.3
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• pp.609-618
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• 2009

The study examined the effects of parenting process(supportive and involving mother-adolescent relationship, father-adolescent relationship) and school process(teachers' support, school life satisfaction) on adolescents' academic achievement and self-evaluation. Participants were 1787 middle school students (902 boys, 885 girls) in KEEP(Korean Education and Employment Panel). Structural equation modeling indicated that parenting and school process influenced adolescents' self-evaluation through adolescents' academic achievement. Also, the analysis with One Way ANOVA revealed that positive school (parenting) processes can serve a protective-stabilizing function when parenting(school) processes are negative.

• Fashion & Textile Research Journal
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• v.2 no.5
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• pp.411-415
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• 2000

To be able to work safely and efficiency, the Threshold Limit Values (TLV) for work in the heat are widely used. Since these TLV are only applicable to workers in regular clothing, TLV should be adjusted when applied to the asbestos removal workers who wear extra impermeable protective clothing. Although abbreviated guidelines for heat stress exposure have been proposed, literature advocating their use in the asbestos removal industry is limited. Therefore, we planed a survey to evaluate the workload of asbestos abatement workers in summer, and an experiment with climatic chambers to evaluate the effects of resting in a cool environment between work periods. From these studies, we got following conclusions. There is a high risk of suffering from heat illness by asbestos abatement work in summer in Japan. It is proposed to create a cool room inside the workplace of asbestos abatement work to reduce thermal stress.

• Textile Coloration and Finishing
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• v.20 no.4
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• pp.31-42
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• 2008

Tricrecyl phosphate(TCP)-containing polyurea microcapsules were prepared by interfacial polymerization using aromatic 2,4-toluene diisocyanate(TDI) and ethylenediamine(EDA) as wall forming materials. The effects of the protective colloids of polyvinylalcohol(PVA) and gelatin were investigated through experimentation. The mean size of prepared polyurea microcapsules was smaller and the surface morphology of the microcapsule prepared by the PVA as protective colloid was much smoother than the gelatin. As the concentration of protective colloid increased, the wall membrane of the polyurea microcapsules became more stable, the thermal stability of the wall membrane increased, the mean particle size became smaller, and the particle distribution was more uniform. PET containg microTCPs have a higher activation energy of decomposition, higher char content and lower heat of combustion.

• Journal of Ginseng Research
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• v.33 no.4
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• pp.305-310
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• 2009

Phenanthrene, one of the polycyclic aromatic hydrocarbons, has been known to be toxic to the environment. In this investigation, the protective effect of red ginseng on phenanthrene-induced oxidative DNA damage was evaluated using Comet assay in A549 cells. Red ginseng's cytoprotective effect on phenanthrene-induced hemolysis was also investigated. This study's findings show that oxidative DNA damage and hemolysis were significantly prevented by red ginseng treatment. Notably, it was found that pulverizing red ginseng into ultra-fine particles even enhanced its protective effects against DNA damage and hemolysis. The results suggest that particle size reduction seems to effectively enhance red ginseng's pharmacological efficacies.

• Corrosion Science and Technology
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• v.7 no.1
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• pp.22-26
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• 2008

Formation of protective iron carbonate films in $CO_2$ corrosion can reduce corrosion rate substantially and the effects have been incorporated in various prediction models. The $CO_2$ corrosion with the presence of free acetic acid is known to increase corrosion rate below scaling temperature. The possible interaction between the formation of iron acetate and iron carbonate films can affect the protectiveness of the film. The study is done using 3% NaCl solution under stagnant $CO_2$ -saturated condition at the scaling temperatures at various pH values and HAC concentrations. The result show that the presence of HAc does not affect the formation of protective iron carbonate film but delays the attainment of protective iron carbonate due to a possibility of solubilising of ferrous ions and thinning of the films.

• Proceedings of the Korean Institute of IIIuminating and Electrical Installation Engineers Conference
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• 2009.05a
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• pp.344-347
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• 2009

Surge protective devices (SPD) have a special position because of the expectation that they perform an effective protective function against various kinds of surges. However, there exists a misconception that the SPD satisfying lower measured limiting voltage (MLV) should also protect equipment against temporary overvoltages (TOVs) as well. This paper inspects various types of MOV based SPDs and carry out experiments on the side effects of the low MLV characteristics. The experiment results show that a low MLV could cause a higher TOV-induced SPD failure rate in the field.

• Journal of the Korean Society of Food Science and Nutrition
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• v.26 no.6
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• pp.998-1005
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• 1997

Kimchi showed protective effect from oxidative damage generated by hydrogen peroxide and paraquat. To investigate the major components of kimchi which reduce the cytotoxicity against reactive oxygen species, keratinocyte(A431, epidermoid carcinoma, human) and fibroblast(CCD-986SK, normal control, human) were cultured under oxidative stress condition provoked by paraquat, a superoxide anion generator, and hydrogen peroxide in the absence or presence of kimchi ingredients. Most keratinocyte and fibroblast cells were killed by hydrogen peroxide and paraquat over 1mM concentration, but kimchi ingredients showed protective effects from oxidative damage generated by hydrogen peroxide and onion, among those, garlic showed the most remarkable preventive effect. Most of kimchi ingredients showed protective effect against paraquat, especially leek notably increased cell survival. For fibroblast cells, ginger had the preventive effect against paraquat, especially leek notably increased cell survival. For fibroblast cells, ginger had the preventive effect from cell killing by high dose of hydrogen peroxide, but most ingredients were not effective against paraquat.