• Korean Journal of Occupational Health Nursing
• /
• v.29 no.4
• /
• pp.363-371
• /
• 2020

Purpose: This study aimed to evaluate the effect of information regarding health and safety risks on the subjective health status of workers using data from the Fifth Korean Working Conditions Survey. Methods: Among the survey respondents, 30,094 people classified as salaried workers, of which 8,513 (28.3%) used protective equipment. Results: Although the majority of workers using protective equipment reported being well-informed about safety and health risks, 15% of them were still insufficiently informed. Multivariate analyses have shown that the subjective health status of workers using protective equipment was significantly better if they received sufficient information. When the workers using protective equipment were classified by the kinds of hazards they were exposed to, the satisfaction of information was also significantly beneficial for the subjective health status of all groups. However, in workers who did not use protective equipment, information satisfaction did not appear to be a significant factor. Conclusion: These results suggest that when providing information on safety and health risks, it is necessary to focus on workers using protective equipment, for whom the effects of the policy are clearly expected.

• Journal of the Korean Society of Clothing and Textiles
• /
• v.33 no.5
• /
• pp.817-826
• /
• 2009

As UV radiation to the earth increased over recent years, many adverse effects of UV radiation have been reported. There are needs to develop UV-protective apparel and accessaries to protect skin from these harmful effects. Cellulose is one of the most frequently worn fiber during summer time. However, celllulose shows very low UV-protective property especially in case of thin and low fabric content. In this study, UV-protective cellulose textiles were developed using chiotsan mordanting and green tea dyeing. The repetition effect of chitosan and green tea treatment were focused. Three different cellulose fibers, cotton, linen, and ramie, were used for this study. All chitosan mordanted and green tea dyed fabrics showed increases in UV-protective property. The color of fabrics tended to darker as the numbers of mordanting process and green tea dyeing increased. UV-protective property did not increase significantly upon the repetition of mordanting and green tea dyeing treatment except ramie fabric. UV protective property was persisted upon washfastness test in all three cellulose fiber types.

• Radiation Oncology Journal
• /
• v.33 no.2
• /
• pp.66-74
• /
• 2015

Trace elements play crucial role in the maintenance of genome stability in the cells. Many endogenous defense enzymes are containing trace elements such as superoxide dismutase and metalloproteins. These enzymes are contributing in the detoxification of reactive oxidative species (ROS) induced by ionizing radiation in the cells. Zinc, copper, manganese, and selenium are main trace elements that have protective roles against radiation-induced DNA damages. Trace elements in the free salt forms have protective effect against cell toxicity induced by oxidative stress, metal-complex are more active in the attenuation of ROS particularly through superoxide dismutase mimetic activity. Manganese-complexes in protection of normal cell against radiation without any protective effect on cancer cells are more interesting compounds in this topic. The aim of this paper to review the role of trace elements in protection cells against genotoxicity and side effects induced by ionizing radiation.

• Proceedings of the Korean Institute of Building Construction Conference
• /
• 2013.05a
• /
• pp.27-28
• /
• 2013

This study investigates the effect of a protective layer on the level of carbonation resistance of concrete. For the protective layer, a PE film, bubble sheets, double layered bubble sheets and styroform were placed in a mold before placing the concrete. In addition, PE film was retrofitted by attaching on the surface of the substrate concrete with a glue. Results showed that the carbonation depths of the control concrete were 4.6 mm and 5.2 mm at one week and two weeks exposure in an accelerated carbonation chamber, whereas the concrete with all types of protective layer except PE flim did not allow the ingress of carbon dioxide during the same period.

• Journal of Life Science
• /
• v.8 no.4
• /
• pp.464-471
• /
• 1998

This study was carried out to determine whether Kamihaengche-tang plus Yukmijihwang-tang (KCYH) exerts the protective effect against oxidant-induced liver cell injury. Cell injurt was estimated by measuring lactate dehydrogenase (LDH) and alanine aminotransferase (ALT) release, and lipid peroxidation was estimated by measuring malondialdehyde, a product of lipid peroxidation in rabbit liver slices. $H_2O_2$increased LDH release which was significantly prevented by 1% KCYHT. The protective effect of KCYH against $H_2O_2$-induced cell injury was dose-dependent in the range of 0.05-1% concentrations. Similary, KCYH inhibited $H_2O_2$ induced lipid peroxidation in a dose-dependent manner. When liver tissuse were exposed to Hg(0.5 mM), ALT activity in the medium and lipid erpoxidation in tissues were markedly increased. These changes were prevented by 1% KCYH. KCHY restored Hg-induced inhibition of cellular GSH content. These result indicate that KCYH exerts the protective effect oxidant-induced liver cell injury, and this effect is attributed to prevented to prevention of lipid peroxidation. These dffects may be due to an increase in concentration of endogenous antioxidants.

• The Korea Journal of Herbology
• /
• v.20 no.2
• /
• pp.115-125
• /
• 2005

Objectives : Polygalae Radix (PR) from Polygalae tenuifolia (Polygalaceae) has been clinically used as a sedative, anti-inflammatory, and anti-bacterial agent. To extend pharmacological effects of PR in the central nervous system (CNS) on the basis of its CNS protective effect, the present study was conducted to identify the effect of PR, whether it shows the neuroprotective action against excitatory neurotoxicity. Methods : To identify the protective effect of PR to excitatory neuro-toxic agent, the present study was focused on the PR effect on cell death, that was caused by applying NMDA to nerve cell, elevation of $(Ca^{2+})_i$, releasement of glutamate, and ROS generation. Result : 1. PR methanol extract, at the concentration range of 0.05 to 5 g/ml, significantly inhibited NMDA (1 mM)-induced neuronal cell death as well as MK-801 (non competitive NMDA antagonist). 2. PR methanol extract $(0.5\;{\mu}g/ml)$ inhibited NMDA (1 mM)-induced elevation of cytosolic calcium concentration $[Ca^{2+}]_i$. NMDA application in the presence of MK-801 $(10\;{\mu}M)$ failed to produce the increase of $[Ca^{2+}]_i$ through all the measurement time. 3. PR methanol extract $(0.5\;{\mu}g/ml)$ inhibited the NMDA-induced elevation of glutamate release. Also, MK-801 showed similar protective effects. 4. PR methanol extract $(0.5\;{\mu}g/ml)$ inhibited the NMDA-induced elevation of ROS generation. Also, MK-801 showed similar protective effects. Conclusion : The present study provides the availability of PR to exert its protective effect on the neuronal cell death in various neurodegenerative pathophysiological conditions.

• Journal of Physiology & Pathology in Korean Medicine
• /
• v.17 no.6
• /
• pp.1524-1527
• /
• 2003

In this study, we demonstrated the antioxidant effect of the Caesalpinia sappan L. extract through the scavenging effect against 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical and the protective effect on protein damage and PC12 cells against cupric ion/hydrogen peroxide. Its IC/sub 50/ value of the scavenging effect against DPPH radical was 7.7 ㎍. Protection of its extract against oxidative bovine serum albumin (BSA)damage induced by hydrogen peroxide was more effective than that of vitamin C. The protective effect on PC12 cells by hydrogen peroxide was shown to be more potent in is extract than in vitamin C. DNA fragmentation analysis also supports this result.

• Journal of Physiology & Pathology in Korean Medicine
• /
• v.17 no.2
• /
• pp.447-450
• /
• 2003

To clerify the cytotoxicity of reactive oxygen species in cultured hippocampal neurons of neonatal mouse, toxic effect was measured by MTT assay after cultured cells were incubated for 3 hours in the media containing 1～40 μM concentrations of H₂O₂. In addition, the protective effect of vitamin E was determined in these cultrures. Cell viability was significantly decreased in a dose-dependent manner after exposure of 10 μM H₂O₂ to cultured mouse hippocampal neurons for 5 hours. In the protective effect of vitamin E, vitamin E prevented the H₂O₂-induced cytotoxicity in these cultures. From these results, it suggests that H₂O₂ has toxic effect in cultured mouse hippocampal neurons and vitamin E has protective effect on the cytotoxicity induced by H₂O₂.

• Journal of the Korean Society of Food Science and Nutrition
• /
• v.26 no.6
• /
• pp.998-1005
• /
• 1997

Kimchi showed protective effect from oxidative damage generated by hydrogen peroxide and paraquat. To investigate the major components of kimchi which reduce the cytotoxicity against reactive oxygen species, keratinocyte(A431, epidermoid carcinoma, human) and fibroblast(CCD-986SK, normal control, human) were cultured under oxidative stress condition provoked by paraquat, a superoxide anion generator, and hydrogen peroxide in the absence or presence of kimchi ingredients. Most keratinocyte and fibroblast cells were killed by hydrogen peroxide and paraquat over 1mM concentration, but kimchi ingredients showed protective effects from oxidative damage generated by hydrogen peroxide and onion, among those, garlic showed the most remarkable preventive effect. Most of kimchi ingredients showed protective effect against paraquat, especially leek notably increased cell survival. For fibroblast cells, ginger had the preventive effect against paraquat, especially leek notably increased cell survival. For fibroblast cells, ginger had the preventive effect from cell killing by high dose of hydrogen peroxide, but most ingredients were not effective against paraquat.

• Korean Journal of Social Welfare
• /
• v.59 no.2
• /
• pp.251-275
• /
• 2007

The purpose of this study was to investigate the relationship between child maltreatment, protective factors, and resilience in elementary school students. It was especially focused on what direct effect of the risk factor(child maltreatment) and protective factors to child resilience, and how protective factors affect the resilience of maltreated child. In the concrete, this study intended to find out whether protective factors mediate between child maltreatment and resilience. This study based on data from the first wave of 'Korean Youth Panel Survey(KYPS)' and subjects consisted of 2,844 4th grade elementary school students. In addition, to test the proposed models, the Mplus-structural equation modeling-was used. The major findings are as follows: First, when child maltreatment increased, resilience decreased. Second, when protective factors increased, resilience increased. Third, protective factors act as buffers against the negative effects of child maltreatment on resilience by mediation. Results indicated that child maltreatment related negatively to resilience and protective factors related positively to resilience. In addition, a mediational model in which protective factors mediates child maltreatment and resilience was supported. In conclusion, various theoretical and practical implications for social work practice focusing on the maltreated children were discussed.