• 한국군사과학기술학회지
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• 제17권2호
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• pp.275-281
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• 2014

Although self-propelled artilleries are mobile equipment, they need their own covered-positions for survival against preemptive strikes. The most important military requirement is enough protective capacity against blast pressure caused by explosion. This paper aims to assess the protective capacity of the newly-placed concrete box-type artillery positions using accurate structural geometric models as well as soil-structure interaction analysis. The commercial program is used to model the structural geometry of the positions. In order to describe the correct wave propagation in the backfill along with soil-structure interaction, used parameters in shock equation of state are selected based on the related studies as well as theories and then their final results are verified with the ones calculated with empirical equations in the US Unified Facility Criteria. In sum, it could be concluded that the protective capacity of the newly-built positions satisfies the protective structural requirement.

• 대한안전경영과학회지
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• 제24권1호
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• pp.11-19
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• 2022

In order to find out the management and sanitation status of protective gear provided at the construction site, a case study and survey were conducted by visiting the site. As a result of the case study, inspection and management, disinfection, and storage of protective equipment were insufficient in both workplaces with less than 50 employees and workplaces with more than 100 employees. As a result of the survey, workers(66.2%), said they did not know how to identify hard hats(67.6.%), how to identify bad hard hats(60.8%), and how to identify bad safety belts (73.0%), even though workers(66.2%) were educated on protective gear, and those in charge of protective gear Non-specified(56.8%), regular inspection of the provided protective equipment was not performed(82.4%), and disinfection was not performed(90.5%). Therefore, as a management plan to maintain the performance of personal protective equipment, educational aspects, regular training on protective equipment, training on how to identify defective protective equipment, management of recording papers, technical aspects, strengthening of standards for placement of dedicated safety managers in small workplaces, participation of workers' representatives when selecting protective equipment, and selection of protective equipment for workers Providing opportunities, administrative aspects of protective equipment regulation and management, introduction of sanitary and cleanliness system, and selection of personnel in charge of protective equipment management were suggested.

• 산업기술연구
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• 제22권A호
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• pp.169-176
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• 2002

The purpose of this paper is to investigate for strain measurement of concrete pavement slab at field. The early-age behaviors of concrete pavement were measured using the strain gages. From the static and dynamic wheel loading tests, the outputs from each gages were recorded. The measured data, also, was compared to those from finite element analysis. The static wheel loading tests were performed in twice, and the dynamic wheel loading tests were performed at the speed 10km-50km. The results could be summarized as follows: To embed the strain gage accurately and stably in concrete pavement, a chair and protective box must be used. The protective box must not be affected from the outside vibrating. From the results of early-age stram measurement, it was found that the strain varied at the maximum value of $180{\mu}{\varepsilon}$ From the results of static wheel loading tests, A1, A2 and B gages generally developed a consistent tendency When comparing the results from the measured at field and the calculated by FEM analysis, the data of A1 and B gages were similar to that from theory. The values from the field test were generally higher than that from the theory. From the results of dynamic wheel loading tests, it was known that the measured strain at field became smaller as the truck speed became faster, Indicating the maximum at the range of $12{\sim}13{\mu}{\varepsilon}$.

• Advances in concrete construction
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• 제12권6호
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• pp.517-525
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• 2021

More underground structures are increasingly being constructed such as box culverts for electric power transmission, and the life extension of these structures is very important. It is well known that the steel embedded in concrete is usually invulnerable to corrosion because the high alkalinity of the pore solution in concrete generates a thin protective oxide layer on the surface of the steel. Recent observations in the field and experimental evidence have shown that even steel in concrete can be corroded through the carbonation reaction of cover concrete. Carbonation-induced corrosion in concrete may often occur in a high carbon dioxide environment. In this study, the risk of carbonation of underground box culverts in Korea was evaluated by measuring the car¬bonation rate and concrete cover depth in the field. Then, the carbonation-free service life for the cover depth of the steel was calcu¬lated with in situ information and Monte Carlo simulation. Additionally, an accelerated carbonation test for a cracked beam specimen was performed, and the effect of a crack on the service life of a box culvert was numerically investigated with Monte Carlo simulation based on experimental results.

• 한국건축시공학회:학술대회논문집
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• 한국건축시공학회 2013년도 추계 학술논문 발표대회
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• pp.88-89
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• 2013

For the purpose of launching strikes, initial survivability of self-propelled artilleries is of crucial importance despite the fact that they are mobility weapon systems. This study identifies the combat placement possibility of the reinforced concrete box-type artillery positions, which might enable the replacement of the current igloo-types, in terms of cost and protection capability. In the numerical analysis the obtained numerical values have proved that these facilities have sufficient protection capability. In addition, it could be concluded that these facilities are also cost-competitive, if more than five positions are constructed simultaneously.

• 운동영양학회지
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• 제24권2호
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• pp.11-21
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• 2020

[Purpose] Doxorubicin (DOX) is a potent anti-cancer drug that appears to have severe myotoxicity due to accumulation. The skeletal muscle has a regeneration capacity through satellite cell activation when exposed to extracellular stimulus or damage. Endurance exercise (EXE) is a therapeutic strategy that improves pathological features and contributes to muscle homeostasis. Thus, this study investigated the effect of EXE training in mitigating chronic DOX-induced myotoxicity. [Methods] Male C57BL/6J mice were housed and allowed to acclimatize with free access to food and water. All the mice were randomly divided into four groups: sedentary control (CON, n=9), exercise training (EXE, n=9), doxorubicin treatment (DOX, n=9), doxorubicin treatment and exercise training (DOX+EXE, n=9) groups. The animals were intraperitoneally injected with 5 mg/kg/week of DOX treatment for 4 weeks, and EXE training was initiated for treadmill adaptation for 1 week and then performed for 4 weeks. Both sides of the soleus (SOL) muscle tissues were dissected and weighed after 24 hours of the last training sessions. [Results] DOX chemotherapy induced an abnormal myofiber's phenotype and transition of myosin heavy chain (MHC) isoforms. The paired box 7 (PAX7) and myoblast determination protein 1 (MYOD) protein levels were triggered by DOX, while no alterations were shown for the myogenin (MYOG). DOX remarkably impaired the a-actinin (ACTN) protein, but the EXE training seems to repair it. DOX-induced myotoxicity stimulated the expression of the forkhead box O3 (FOXO3a) protein, which was accurately controlled and adjusted by the EXE training. However, the FOXO3a-mediated downstream markers were not associated with DOX and EXE. [Conclusion] EXE postconditioning provides protective effects against chronic DOX-induced myotoxicity, and should be recommended to alleviate cancer chemotherapy-induced late-onset myotoxicity.

• 한국항해항만학회지
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• 제43권6호
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• pp.444-449
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• 2019

국제항해선박과 국내항해 카페리선박에 적용되었던 "화물적재고박 등에 관한 기준"이 2018년 1월부터 국내 항만을 운송하는 일반화물선박에도 적용 되었다. 이에 따라 일반화물선을 통해 제주도를 기점으로 국내 주요항만으로 운송되고 있던 크기와 형태가 다른 비표준 철재상자와 같은 새로운 형식의 화물에 대한 법적인 성질을 분류하고 그 분류에 따라 안전하게 적재하고 고박할 수 있는 방안이 필요하게 되었다. 본 연구는 현장 조사와 관련기관 자료 수집을 통해 철재상자의 크기, 형태 등을 분석하였고, 이를 기반으로 철재상자의 법적인 지위를 관련 국내법령과 국제규범을 비교 분석하였으며 그 검토결과를 바탕으로 일반화물선의 화물창에 안전하게 적재하고 고박하는 방법을 검토하였다. 철재상자는 관련 국내법령과 국제규범 등에 따르면 비표준화 화물의 한 종류인 보호외벽이 있는 팔렛트 상자로 분류할 수 있었다. 또한, 일반선박의 화물창에 철재상자를 적재하는 경우 선박 화물창에 빈틈이 없도록 꽉채워서 적재하여 운송하는 방안이 검토되었다. 검토된 화물창내 빈틈없이 꽉채우는 적재·운송 방안이 안전한지에 대한 검증은 선체구조 안전성과 선박복원성 확보 여부를 통해 확인하였다. 선체구조 안전성에 대한 검증결과 화물창내에 적재할 수 있는 화물의 총중량에 대한 선박의 화물창 바닥과 양측면의 구조강도 값은 만족하였으며, 선박복원성은 GoM 값과 3가지 횡경사각별 복원정곡선 및 복원정이 만족되었다.

• The Korean Journal of Physiology and Pharmacology
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• 제27권2호
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• pp.167-176
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• 2023

This study aims to explore the impact of Rehmannioside D (RD) on ovarian functions of rats with diminished ovarian reserve (DOR) and its underlying mechanisms of action. A single injection of cyclophosphamide was performed to establish a DOR rat model, and fourteen days after the injection, the rats were intragastrically administrated with RD for two weeks. Rat estrus cycles were tested using vaginal smears. Ovarian tissues were histologically evaluated, the number of primordial, mature, and atretic follicles was calculated, and the apoptotic rate of granulosa cells. Follicle-stimulating hormone (FSH), luteinizing hormone (LH), and estradiol (E₂) levels were determined by ELISA assays. Protein levels of Forkhead Box O1 (FOXO1), KLOTHO, Bcl-2, and Bax were investigated in ovarian tissues of DOR rats. The binding between FOXO1 and KLOTHO was verified by ChIP assay. High-dose administration of RD into DOR rats improved their estrus cycles, increased ovarian index, enhanced the number of primordial and mature follicles, reduced the number of atretic follicle number, and ovarian granulosa cell apoptosis in addition to inhibiting FSH and LH levels and upregulating E₂ expression. FOXO1 and KLOTHO were significantly suppressed in DOR rats. FOXO1 knockdown partially suppressed the protective effects of RD on DOR rats, and KLOTHO overexpression could restore RD-induced blockade of DOR development despite knocking down FOXO1. FOXO1 antibody enriched KLOTHO promoter, and the binding between them was reduced in DOR group compared to that in sham group. RD improved ovarian functions in DOR rats and diminished granulosa cell apoptosis via the FOXO1/KLOTHO axis.

• 한국의학물리학회지:의학물리
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• 제9권3호
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• pp.137-141
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• 1998

납공 (lead ball)과 쇠공(steel ball)을 고에너지 광자선에 대한 차폐재로 이용하는 것이 가능한가를 평가하고 ,4～10MV 엑스선 차폐를 위한 납공과 쇠공의 물리자료를 구하는 것이 목적이다. 직경이 각각 2.0-2.5mm, 1.5-2.0mm 인 납공 및 쇠공을 폭이 균일한 아크릴 용기에 채워, 두께의 균일성 확인을 위해 MV 엑스선사진을 촬영하였으며, 금속공의 평균 밀도와 4～10MV 엑스선에 대한 선감쇠계수를 측정하였다. 선감쇠계수를 측정할 때 Farmer 이온함을 이용하였으며 산란선의 효과를 최소화하기 위해 70cm 거리에서 조사면크기는 5.5cm$\times$5.5cm로 하였다. 비교하기 위해 납판과 철판에 대해서도 같은 종류의 변수를 구하였다. 금속구를 용기에 채웠을 때 분포는 균일하였으며, 납 -공기 혼합물의 밀도는 6.93g/$cm^3$이었으며, 철-공기 혼합물의 밀도는 4.75g/$cm^3$ 이었다. 납의 밀도에 대한 납-공기 혼합물의 밀도의 비는 0.611, 철에 대한 철-공기 혼합물의 밀도의 비는 0.604이었다. 납-공기 혼합물의 반가층은 4MV, 6MV, 10MV 엑스선 각각에 대하여 1.89cm, 2.07cm, 2.16cm 이었으며 납판 반가층의 약 1.64배였다. 철-공기 혼합물의 반가층은 4MV, 6MV, 10MV 엑스선 각각에 대하여 3.24cm, 3.70cm, 4.15cm 이었으며 철판 반가 층의 약 1.65 배였다. 금속구는 용기속에 고르게 채워질 수 있기 때문에 차폐재료로 쓸 수 있다. 납공과 쇠공이 고르게 채워질 때 밀도는 각각 6.93g/$cm^3$, 4.75g/$cm^3$ 이었으며 각각의 반가층은 납 또는 철의 반가층의 1.65배였다. 밀도와 반가층을 곱한 값은 공이나 판에 대해 같은 값이었다.

• Composites Research
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• 제19권1호
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• pp.9-14
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• 2006

본 연구는 KS F 2278 2003 (창호의 단열성 시험 방법)에 의하여 철도차량 및 버스의 내/외장재로 적용 가능한 카본/에폭시 스킨-알루미늄 하니콤 & 발사코어 샌드위치 판넬(두께 : 37mm), 카본/에폭시 스킨-알루미늄 하니콤 코어 샌드위치 판넬(두께 : 57mm, 단열재 포함) 및 카본/에폭시 스킨-알루미늄 하니콤 코어 샌드위치 판넬(두께 : 37mm)에 대한 열관류율 시험을 하였다. 또한 KS F2277 . 2002 (건축용 구성재의 단열성 측정방법-교정열상자법 및 보호열상자법)에 의하여 추가로 알루미늄 스킨-알류미늄 하니콤 샌드위치 판넬들 (두께 : 27mm, 35n1m)과 알루미늄 스킨-포밍 알루미늄 샌드위치 판넬 (두께27mm)에 대한 열관류율 시험을 수행하였다. 본 연구를 통해 면제와 심재사이에 열전달은 실제 단면적이 넓을수록 열관류율이 높았으며, 하이브리드형 복합재 일수록 단열성능이 우수함을 확인하였다.