• 한국산학기술학회논문지
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• 제15권2호
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• pp.638-645
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• 2014

컨테이너 물동량 증대에 따라 항만 내 타부두 간 환적 물동량 수요가 크게 증대되었으나, 기존 YT 방식의 타부두 환적은 이를 효율적으로 뒷받침하지 못하고 있다. 본 논문은 컨테이너항만의 경쟁력 향상을 위한 컨테이너 대용량 이송장치 개발방안을 제시하였다. 시스템 대안의 장단점 분석과 국내 터미널 운영형태를 고려하여 2단적재 다중 편성시스템(DMTS)을 최종 대안으로 선정하였다. DMTS 회전반경은 13.5m로, 국내 기존 항만의 layout에서 즉시 운용 가능할 것으로 판단된다. 특허분석을 통하여 DMTS 핵심기술 항목으로서 현가 조향장치 최적설계, 동력 및 동력전달 장치, 주행제어 및 안전감시장치, 그리고 트레일러 간 연결기 등을 도출하였다. DMTS는 국내 수출입 항만에 적용하는데 문제가 없으며 단위 수송용량이 높아 운영 효율성 개선에 기여할 것으로 판단된다.

• 대한방사성의약품학회지
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• 제2권1호
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• pp.43-50
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• 2016

$^{89}Zr$ with the favorable nuclear decay kinetics and chemical properties is an appealing radiometal for its application in immuno-PET using radiolabeled monoclonal antibodies. Rising demand of ultrahigh purity and high-specific activity $^{89}Zr$ has propelled the radiochemist worldwide to develop an overall efficacious method for its promising separation from the target matrix $^{89}Y$. The requirement of elevated radiochemical purity (${\geq}$ 99.99%) has accelerated the efforts since last two decades to achieve higher decontamination and separation factors of carrier free $^{89}Zr$ over $^{89}Y$ using several suitable separation techniques. However, each of the technique has its own pros and cons which prior to its actual medical application needs to be optimized and thoroughly scrutinized to avoid further complications during radiolabelling of the pharmaceuticals. In this short review article we will specifically consider as well focus on the historical development and the recent advances on the radiochemical separation of $^{89}Zr$ from $^{89}Y$ which will be helpful for the separation scientist involved in this area to understand the existing available means and plan the strategy to investigate and develop the novel techniques to overcome the problems involved in the present methods.

• ALGAE
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• 제28권2호
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• pp.131-147
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• 2013

Major progress has been made in the past decade towards understanding of the biosynthesis of red carotenoid astaxanthin and its roles in stress response while exploiting microalgae-based astaxanthin as a potent antioxidant for human health and as a coloring agent for aquaculture applications. In this review, astaxanthin-producing green microalgae are briefly summarized with Haematococcus pluvialis and Chlorella zofingiensis recognized to be the most popular astaxanthin-producers. Two distinct pathways for astaxanthin synthesis along with associated cellular, physiological, and biochemical changes are elucidated using H. pluvialis and C. zofingiensis as the model systems. Interactions between astaxanthin biosynthesis and photosynthesis, fatty acid biosynthesis and enzymatic defense systems are described in the context of multiple lines of defense mechanisms working in concert against photooxidative stress. Major pros and cons of mass cultivation of H. pluvialis and C. zofingiensis in phototrophic, heterotrophic, and mixotrophic culture modes are analyzed. Recent progress in genetic engineering of plants and microalgae for astaxanthin production is presented. Future advancement in microalgal astaxanthin research will depend largely on genome sequencing of H. pluvialis and C. zofingiensis and genetic toolbox development. Continuous effort along the heterotrophic-phototrophic culture mode could lead to major expansion of the microalgal astaxanthin industry.

• 한국해양바이오학회지
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• 제5권4호
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• pp.15-25
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• 2011

Marine sponges are a rich source of highly diversified bioactive compounds. These medicinally valuable molecules represent extreme physiological and ecological functions in sponges, more presumably involving in the resistance to the feeding by other marine organisms like fish and fouling by barnacles, bacteria, fungi, etc. This feature of attaining resistance made sponges as successful poriferans that possess an impressive array of biological properties ranging from antimicrobial to anticancerous activities. The diversified bioactive principle of sponges might be due to their spacio-temporal distribution and although, the gateway for exploiting the sponges for isolating these distinct, potential molecules is open, suitable technical and methodological approaches are yet to be implemented in order to bring the sponges as successful pharmaceutical leads in the field of marine biotechnology. Despite of the identified difficulties of marine sponge research from past few decades, one should concentrate not only on the basic and applied technical/methodological considerations, but also on the novel strategies like in vitro sponge cell, fragment and whole sponge culture; sponge symbiont cell culture; in situ and ex situ sponge cultivation; and sponge bioreactors and metagenomic approaches, for the successful exploitation of marine sponges towards the novelty in sponge biotechnology. The present review narrates the pros and cons of the nowadays-marine sponge research by focusing on the suggestive ecobiotechnological approaches, based on the latest studies for feasible ecological exploitation and biotechnological application of sponges from the sea.

• 대한두경부종양학회지
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• 제35권1호
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• pp.1-11
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• 2019

In head and neck reconstruction, microsurgeons are faced with various demands, such as thin resurfacing, or three-dimensional reconstruction, and therefore, conventional flap as well as perforator flaps are all useful for the functional and aesthetic reconstruction successfully. Among perforator flaps, the pros and cons of anterolateral thigh perforator flap(ALTp) and thoracodorsal perforator flap(TAp) is compared and selected depending on the surgeon's preference, recipient site condition or patient status. Both flaps can be elevated in a chimeric pattern by combining different aspects of tissue components. Customized or tailored reconstruction as well as 3 dimensional reconstructions are all available with perforator flaps and it is useful in head and neck reconstruction. The most outstanding update in head and neck reconstruction is the perforator based island flap (PBIF) compared to conventional flaps. The conventional local flap has evolved on behalf of the perforator concept and its design becomes more flexible and freestyle with less limitations. Actually, random pattern flap is now a misnomer and most conventional local flaps turn into PBIFs. Finally we can say all conventional donor site becomes universal, depending on the surgeons' preference or idea. Moreover, there is no more "flap of choice" and postoperative results are quite variable by surgeons' ability. Operative procedures and plans are very flexible to freestyle flap. With all these advantages, surgeons should be armed with both conventional and perforator concepts for solving any defects or problems.

• Earthquakes and Structures
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• 제4권6호
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• pp.607-627
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• 2013

The application of shape memory alloys (SMAs) to the seismic response reduction of civil engineering structures has attracted growing interest due to their self-centering feature and excellent fatigue performance. The loading rate dependence of SMAs raises a concern in the seismic analysis of SMA-based devices. However, the implementation of micromechanics-based strain-rate-dependent constitutive models in structural analysis software is rather complicated and computationally demanding. This paper investigates the feasibility of replacing complex rate-dependent models with rate-independent constitutive models for superelastic SMA elements in seismic time-history analysis. Three uniaxial constitutive models for superelastic SMAs, including one rate-dependent thermomechanical model and two rate-independent phenomenological models, are considered in this comparative study. The pros and cons of the three nonlinear constitutive models are also discussed. A parametric study of single-degree-of-freedom systems with different initial periods and strength reduction factors is conducted to examine the effect of the three constitutive models on seismic simulations. Additionally, nonlinear time-history analyses of a three-story prototype steel frame building with special SMA-based damping braces are performed. Two suites of seismic records that correspond to frequent and design basis earthquakes are used as base excitations in the seismic analyses of steel-braced frames. The results of this study show that the rate-independent constitutive models, with their parameters properly tuned to dynamic test data, are able to predict the seismic responses of structures with SMA-based seismic response modification devices.

• 대한조선학회논문집
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• 제53권6호
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• pp.482-493
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• 2016

The identification of modal damping of a segmented hull model with torsional response is difficult task due to the coupling of modal response. This is because the 1st and 2nd torsional vibration modes are closely spaced in frequency domain leading to the situation that the modal decomposition is difficult to achieve by simple band-pass filter. Present study applied several different modal decomposition methods to derive the damping ratio of different modes. The modal decomposition methods considered in this study are simple band-pass filter, Hilbert vibration decomposition, Wavelet transform and proper orthogonal decomposition. Coupled free decay signal obtained from the torsional hammering test on a segmented hull model was processed with four different methods and the derived damping ratios were compared with each other. Discussions also have been made on the pros and cons of the different methodologies.

• 한국기록관리학회지
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• 제14권1호
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• pp.75-100
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• 2014

국가기록원 등 많은 기록관에서 온라인 검색도구를 적극 활용하고 있으나 여러 측면에서 개선이 필요한 상황이다. 이에 본 연구에서는 국가기록원을 중심으로, 호주, 영국, 미국의 국립기록관에서 제공하는 온라인 검색도구현황을 분석하였다. 또 호주, 영국, 미국 국립기록관의 검색도구를 직접 사용하여 각각의 장단점을 파악해 보도록 하기 위해, 실제 이용자들을 선정하여 포커스 그룹 인터뷰를 통한 평가를 실시하였다. 그 결과를 기반으로, 전반적 기능 및 계층별 검색, 검색옵션 및 주제어검색, 검색결과제시, 기록정보콘텐츠 서비스 등의 측면에서 온라인 검색도구의 개선 및 발전 방향을 제시하였다.

• Nuclear Engineering and Technology
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• 제46권1호
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• pp.101-108
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• 2014

About 40% of reactors in the world are being operated beyond design life or are approaching the end of their life cycle. During long-term operation, various degradation mechanisms occur. Fatigue caused by alternating operational stresses in terms of temperature or pressure change is an important damage mechanism in continued operation of nuclear power plants. To monitor the fatigue damage of components, Fatigue Monitoring System (FMS) has been installed. Most FMSs have used Green's Function Approach (GFA) to calculate the thermal stresses rapidly. However, if temperature-dependent material properties are used in a detailed FEM, there is a maximum peak stress discrepancy between a conventional GFA and a detailed FEM because constant material properties are used in a conventional method. Therefore, if a conventional method is used in the fatigue evaluation, thermal stresses for various operating cycles may be calculated incorrectly and it may lead to an unreliable estimation. So, in this paper, the modified GFA which can consider temperature-dependent material properties is proposed by using an artificial neural network and weight factor. To verify the proposed method, thermal stresses by the new method are compared with those by FEM. Finally, pros and cons of the new method as well as technical findings from the assessment are discussed.

• 한국BIM학회 논문집
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• 제11권3호
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• pp.75-90
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• 2021

A smart home system improves the elderly's quality of life by monitoring and analyzing their movements and health conditions with better health-care and social support services. Therefore, there has been an effort to adopt a smart home system for the independently living elderly. However, to the best of our knowledge, no study has investigated the usability of a smart home system on actual independently living elderly housing in long-term settings. Thus, this study aims to demonstrate the usability of a smart home system on independently living elders in living lab conditions. The BLE smart band and the BLE receiver were chosen for the smart home system to monitor the movement of the participants in their homes as well as to monitor the heart rates, step counts, sleep index. Nine independent living elderly from the senior welfare center in Kimjae participated in this living lab demonstration experiment for ten months. This demonstration experiment confirmed the effectiveness of low-cost and easily adoptable IoT-based BLE sensor sets on independent living elders and discussed the troubles and limitations of the experiment. By grasping the pros and cons of IoT-based BLE sensor sets, this study seeks to improve the accessibility and usability of smart home systems for the elderly population in independent living arrangements.