• 제목/요약/키워드: Proportional hazards

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Cox 비례위험모형을 따르는 중도절단자료 생성 (Generating censored data from Cox proportional hazards models)

  • 김지현;김봉성
    • 응용통계연구
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    • 제31권6호
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    • pp.761-769
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    • 2018
  • 통계학 연구에 모의실험이 중요하게 쓰이며 중도절단자료를 다루는 생존분석에서도 마찬가지다. 생존분석에서 Cox 모형이 널리 쓰이는데, Cox 모형을 따르는 중도절단자료를 생성하는 방법에 대해 살펴보았다. Bender 등 (Statistics in Medicine, 24, 1713-1723, 2005)은 생존시간을 생성하는 모수적 방법을 제시하였으나 생존시간뿐만 아니라 중도절단시간도 생성해야 중도절단자료를 얻게 된다. 중도절단자료를 생성하기 위한 모수적 방법과 함께 비모수적 방법도 제시하였으며 실제 자료에도 적용해 보았다.

상수관로의 잔존수명 평가를 위한 통계적 방법론 (A Statistical Methodology for Evaluating the Residual Life of Water Mains)

  • 박수완;최창록;김정현;배철호
    • 상하수도학회지
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    • 제23권3호
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    • pp.305-313
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    • 2009
  • This paper provides a method for evaluating a residual life of water mains using a proportional hazard model(PHM). The survival time of individual pipe is defined as the elapsed time since installation until a break rate of individual pipe exceeds the Threshold Break Rate. A break rate of an individual pipe is estimated by using the General Pipe Break Model(GPBM). In order to use the GPBM effectively, improvement of the GPBM is presented in this paper by utilizing additional break data that is the cumulative number of pipe break of 0 for the time of installation and adjusting a value of weighting factor(WF). The residual lives and hazard ratios of the case study pipes of which the cumulative number of pipe breaks is more than one is estimated by using the estimated survival function. It is found that the average residual lives of the steel and cast iron pipes are about 25.1 and 21 years, respectively. The hazard rate of the cast iron pipes is found to be higher than the steel pipes until 20 years since installation. However, the hazard rate of the cast iron pipes become lower than the hazard rates of the steel pipes after 20 years since installation.

비례위험모형을 이용한 수명데이터의 분석 (Analysis of Lifetime Data using Proportional Hazards Model)

  • Kim, Yon Soo;Chung, Young Bae
    • 산업경영시스템학회지
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    • 제20권44호
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    • pp.357-368
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    • 1997
  • 본 연구에서는 의학분야의 생존분석에서 적용되어 왔던 Cox의 비례위험모형을 신뢰성예측 에 적용할 때의 분석절차 및 그에 따른 소프트웨어를 다룬다. 이 비례 위험모형은 신뢰성공학 분야에 적용될 경우 많은 잠재력을 가지고 있으나, 그 분야에 적용된 경우가 많지 않고, 이미 적용된 사례들도 잘못 적용되어 왔다는 지적이 많은 실정이다. 본 연구에서는 시스템 , 서브시스템, 부품수준에서의 각 라이프사이클을 거치며 얻어진 수명데이타를 분석하여 신뢰도를 예측할 수 있는 모형을 설정하고, 그에 따른 소프트웨어를 다루며, 이 방법의 개관, 장단점, 주의점등을 고찰한다.

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Controling the Healthy Worker Effect in Occupational Epidemiology

  • 김진흠;남정모
    • 한국통계학회:학술대회논문집
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    • 한국통계학회 2002년도 추계 학술발표회 논문집
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    • pp.197-201
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    • 2002
  • The healthy worker effect is an important issue in occupational epidemiology. We proposed a new statistical method to test the relationship between exposure and time to death in the presence of the healthy worker effect. In this study, we considered the healthy worker hire effect to operate as a confounder and the healthy worker survival effect to operate as a confounder and an intermediate variable. The basic idea of the proposed method reflects the length bias-sampling caused by changing one's employment status. Simulation studies were also carried out to compare the proposed method with the Cox proportional hazards models. According to our simulation studies, both the proposed test and the test based on the Cox model having the change of the employment status as a time-dependent covariate seem to be satisfactory at an upper 5% significance level. The Cox models, however, are inadequate with the change, if any, of the employment status as time-independent covariate. The proposed test is superior in power to the test based on the Cox model including the time-dependent employment status.

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Bayesian Semi-Parametric Regression for Quantile Residual Lifetime

  • Park, Taeyoung;Bae, Wonho
    • Communications for Statistical Applications and Methods
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    • 제21권4호
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    • pp.285-296
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    • 2014
  • The quantile residual life function has been effectively used to interpret results from the analysis of the proportional hazards model for censored survival data; however, the quantile residual life function is not always estimable with currently available semi-parametric regression methods in the presence of heavy censoring. A parametric regression approach may circumvent the difficulty of heavy censoring, but parametric assumptions on a baseline hazard function can cause a potential bias. This article proposes a Bayesian semi-parametric regression approach for inference on an unknown baseline hazard function while adjusting for available covariates. We consider a model-based approach but the proposed method does not suffer from strong parametric assumptions, enjoying a closed-form specification of the parametric regression approach without sacrificing the flexibility of the semi-parametric regression approach. The proposed method is applied to simulated data and heavily censored survival data to estimate various quantile residual lifetimes and adjust for important prognostic factors.

Prediction of the Probability of Customer Attrition by Using Cox Regression

  • Kang, Hyuncheol;Han, Sang-Tae
    • Communications for Statistical Applications and Methods
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    • 제11권2호
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    • pp.227-233
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    • 2004
  • This paper presents our work on constructing a model that is intended to predict the probability of attrition at specified points in time among customers of an insurance company. There are some difficulties in building a data-based model because a data set may contain possibly censored observations. In an effort to avoid such kind of problem, we performed logistic regression over specified time intervals while using explanatory variables to construct the proposed model. Then, we developed a Cox-type regression model for estimating the probability of attrition over a specified period of time using time-dependent explanatory variables subject to changes in value over the course of the observations.

Cox Model 을 이용한 공기압 실린더의 수명예측에 관한 연구 (A Study on Life Prediction of Pneumatic Cylinder using Cox Model)

  • 강보식;김형의;장무성
    • 대한기계학회:학술대회논문집
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    • 대한기계학회 2008년도 추계학술대회A
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    • pp.1387-1390
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    • 2008
  • Pneumatic cylinder is widely used in the various industrial fields. Reliability Study of this field is very important part to the related companies. In this study, we want to predict the life of pneumatic cylinder using Cox (or proportional hazards) model. Used in biomedical applications, the Cox model can be used as an accelerated life testing model. We considered working pressure and temperature as stress factors. The statistical software is used to analyze and forecast the life data.

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Analyzing Clustered and Interval-Censored Data based on the Semiparametric Frailty Model

  • Kim, Jin-Heum;Kim, Youn-Nam
    • 응용통계연구
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    • 제25권5호
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    • pp.707-718
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    • 2012
  • We propose a semi-parametric model to analyze clustered and interval-censored data; in addition, we plugged-in a gamma frailty to the model to measure the association of members within the same cluster. We propose an estimation procedure based on EM algorithm. Simulation results showed that our estimation procedure may result in unbiased estimates. The standard error is smaller than expected and provides conservative results to estimate the coverage rate; however, this trend gradually disappeared as the number of members in the same cluster increased. In addition, our proposed method was illustrated with data taken from diabetic retinopathy studies to evaluate the effectiveness of laser photocoagulation in delaying or preventing the onset of blindness in individuals with diabetic retinopathy.

A Goodness-of-Fit Test for the Additive Risk Model with a Binary Covariate

  • Kim, Jin-Heum;Song, Moon-Sup
    • Journal of the Korean Statistical Society
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    • 제24권2호
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    • pp.537-549
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    • 1995
  • In this article, we propose a class of weighted estimators for the excess risk in additive risk model with a binary covariate. The proposed estimator is consistent and asymptotically normal. When the assumed model is inappropriate, however, the estimators with different weights converge to nonidentical constants. This fact enables us to develop a goodness-of-fit test for the excess assumption by comparing estimators with diffrent weights. It is shown that the proposed test converges in distribution to normal with mean zero and is consistent under the model misspecifications. Furthermore, the finite-sample properties of the proposed test procedure are investigated and two examples using real data are presented.

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Multiprocess Discount Survival Models With Survival Times

  • Shim, Joo-Yong
    • Journal of the Korean Statistical Society
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    • 제26권2호
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    • pp.277-288
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    • 1997
  • For the analysis of survival data including covariates whose effects vary in time, the multiprocess discount survival model is proposed. The parameter vector modeling the time-varying effects of covariates is to vary between time intervals and its evolution between time intervals depends on the perturbation of the next time interval. The recursive estimation of the parameter vector can be obtained at the end of each time interval. The retrospective estimation of the survival function and the forecasting of the survival function of individuals of the specific covariates also can be obtained based on the information gathered until the end of the time interval.

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