• Toxicological Research
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• v.31 no.3
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• pp.255-264
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• 2015

Heterocyclic amines (HCAs) and acrylamide are unintended hazardous substances generated by heating or processing of foods and are known as carcinogenic and mutagenic agents by the animal experiments. A simple method was established for a rapid and accurate determination of 12 types of HCAs (IQ, MeIQ, Glu-P-1, Glu-P-2, MeIQx, Trp-P-1, Trp-P-2, PhIP, $A{\alpha}C$, $MeA{\alpha}C$, Harman and Norharman) and acrylamide in three food matrices (non-fat liquid, non-fat solid and fat solid) by isotope dilution liquid chromatography-tandem mass spectrometry (LC-MS/MS). In every sample, a mixture of internal standards including $IQ-d_3$, $MeIQx-d_3$, $PhIP-d_3$, $Trp-P-2-^{13}C_2-^{15}N$ and $MeA{\alpha}C-d_3$ was spiked for quantification of HCAs and $^{13}C_3$-acrylamide was also spiked for the analysis of acrylamide. HCAs and acrylamide in sample were extracted with acetonitrile and water, respectively, and then two solid-phase extraction cartridges, ChemElut: HLB for HCAs and Accucat: HLB for acrylamide, were used for efficiently removing interferences such as pigment, lipid, polar, nonpolar and ionic compounds. Established method was validated in terms of recovery, accuracy, precision, limit of detection, limit of quantitation, and linearity. This method showed good precision (RSD < 20%), accuracy (71.8~119.1%) and recovery (66.0~118.9%). The detection limits were < 3.1 ng/g for all analytes. The correlation coefficients for all the HCAs and acrylamide were > 0.995, showing excellent linearity. These methods for the detection of HCAs and acrylamide by LC-MS/MS were applied to real samples and were successfully used for quantitative monitoring in the total diet study and this can be applied to risk assessment in various food matrices.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.38 no.2
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• pp.337-347
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• 2018

The government has been operating residential improvement projects through the "Act on the Maintenance and Improvement of Urban Areas and Dwelling Conditions for Residents" as a type of a remedial measure for deteriorated residential areas. However, in recent years, the residential improvement projects have experienced difficulties due to the effects of various factors including the slowdown in economic growth. After observing the depression in a number of projects, various studies have been carried out to investigate the causality and improve the promotion of the residential improvement projects. In the trend of research, this study aims to analyze the effects of land and building characteristics on the improvement projects of Busan Metropolitan City. The dependent variables of the study represent different phases of improvement project as specified in the "Act on the Maintenance and Improvement of Urban Areas and Dwelling Conditions for Residents". The independent variables represent land and building characteristics which refer to the criteria used in the designation process of maintenance area according to the act. The empirical analysis uses the ordered logit model. The results from the analysis suggest that geographical condition, factors related to the number of union members, factors related to the parcel price and condition of a location have impact on the promotion of the improvement project. The results of the analysis show that majority of the factors are related to the economic feasibility of the projects. Residential improvement project is a part of urban planning projects that rehabilitates deteriorated residential environment, and it is closely associated with the quality of life of public. Accordingly, we hope that such projects are reasonable and take effective approach to those with urgent needs rather than to focus on profitability. Also, potential administrative and economical loss should be avoided by taking necessary planning measures in advance.

• Journal of the Korean Society of Marine Environment & Safety
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• v.24 no.3
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• pp.367-372
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• 2018

The objective of this paper is to optimize the cross-section of aluminum decking units used in the bass boats under operating conditions, and to verify the optimized model from the results via by ANSYS software. Aluminum decking unit is needed to endure specific loading while leisure activity and sailing. For a stiffer and more cost-neutral aluminum decking unit, optimization is often considered in the naval and marine industries. This optimization of the aluminum decking unit is performed using the ANSYS program, which is based on the topology optimization method. The generation of finite element models and stress evaluations are conducted using the ANSYS Multiphysics module, which is based on the Finite Element Method (FEM). Through such a series of studies, it was possible to determine the most suitable case for satisfying the structural strength found among the phase-optimized aluminum deck units in bass boats. From these optimization results, CASE 1 shows the best solution in comparison with the other cases for this optimization. By linking the topology optimization with the structural strength analysis, the optimal solution can be found in a relatively short amount of time, and these procedures are expected to be applicable to many fields of engineering.

• Toxicological Research
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• v.31 no.3
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• pp.273-278
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• 2015

The aim of this study was to develop an efficient quantitative method for the determination of acetaldehyde (AA) and formaldehyde (FA) contents in solid and liquid food matrices. The determination of those compounds was validated and performed using gas chromatography-mass spectrometry combined by solid phase micro-extraction after derivatization with O-(2,3,4,5,6-pentafluoro-benzyl)-hydroxylamine hydrochloride. Validation was carried out in terms of limit of detection, limit of quantitation, linearity, precision, and recovery. Then their contents were analyzed in various food samples including 15 fruits, 22 milk products, 31 alcohol-free beverages, and 13 alcoholic beverages. The highest contents of AA and FA were determined in a white wine (40,607.02 ng/g) and an instant coffee (1,522.46 ng/g), respectively.

• Hwankyungkyoyuk
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• v.16 no.2
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• pp.1-14
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• 2003

This study aims to review the present condition of human resources development in environment technology area and to explore the direction of human resources development plans, based on the results of a survey targeting experts in this area. Related papers & literatures are referred and a survey for experts' opinions are carried out. The survey was oriented to the importance and effectiveness of policies designed by Korea Ministry of environment. The main findings of this study are as follows; firstly, an emphasis should be put on generating professionals in charge of creating domestic demand for environmental purposes for promotion to make excellent environmental techniques being of practical use and help them go into businesses was turned out crucial; secondly, it is advised to upgrade the level of qualifications of environmental technicians by reforming into a graduate schoolcentered educational system on a human resource-rearing phase; thirdly, retraining should be provided by law to ensure the enhancement of re-educating the existing environmental technicians; fourth, efforts should be made to promptly develope new techniques and unify declining traditional items, deterring national technical qualification system oriented toward cultivating superintendents in the environment field.

• Korean Journal of Adult Nursing
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• v.18 no.4
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• pp.660-667
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• 2006

Purpose: The purpose of this study was to investigate the effects of 12-week brisk walking and brisk walking plus diet program on C-Reactive Protein(CRP) in middle-aged obese hypertriglycemic($triglyceride{\geq}150mg/d{\ell}$) Korean women. Method: The subjects were 16 obese ($BMI{\geq}25$) hypertriglycemic middle-aged women (7 for brisk walking group, 9 for brisk walking plus diet group) who participated in a health promotion program at one public health center. Initially the brisk walking intervention consisted of walking for 20 minutes/day at an intensity of 40 to 50% of heart rate reserve(HRR) for 3 days/week and progressed to 50 minutes/day, 60 to 70% of their HRR, and 6 days/week. The diet intervention consisted of 60 minutes of group education and 20 to 30 minutes of individual counseling with a nutritionist every week. Data were analyzed with SPSS PC program. Results: There was no significant reduction in CRP levels in both brisk walking (Z=-1.70, p=0.088) and brisk walking plus diet group(Z=-0.31, p=0.752). In brisk walking only group, CRP levels were increased after the intervention. Conclusion: Brisk walking could increase the level of CRP when it is in the course of progression and diet could decrease the acute phase inflammatory response.

• Asia pacific journal of information systems
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• v.15 no.1
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• pp.115-133
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• 2005

This study is to develop an information security management model(ISMM) for small and medium sized enterprises(SMEs). Based on extensive literature review, a five-pillar twelve-component reference ISMM is developed. The five pillars of SME's information security are: centralized decision making, ease of management, flexibility, agility and expandability. Twelve components are: scope & organization, security policy, resource assessment, risk assessment, implementation planning, control development, awareness training, monitoring, change management, auditing, maintenance and accident management. Subsequent survey designed and administered to expose experts' perception on the importance of these twelve components revealed that five out of tweleve components require relatively immediate attention than others, especially in SME's context. These five components are: scope and organization, resource assessment, auditing, change management, and incident management. Other seven components are policy, risk assessment, implementation planning, control development, awareness training, monitoring, and maintenance. It seems that resource limitation of SMEs directs their attention to ISMM activities that may not require a lot of resources. On the basis of these findings, a three-phase approach is developed and proposed here as an SME ISMM. Three phases are (1) foundation and promotion, (2) management and expansion, and (3) maturity. Implications of the model are discussed and suggestions are made for further research.

• 한국컴퓨터산업교육학회:학술대회논문집
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• 2003.11a
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• pp.105-110
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• 2003

Number of information users of industry, school and research institute with arrival of knowledge information society are in trend that increase gradually the 21th century. Manufacture user number of database been circulating is examined to fourteen million, six hundred and twenty-four thousand people in internal until end of 2002 if follow to Korea data base promotion center, this shows increase more than yearly mean $70\%$ every year by increasing provision $70.3\%$ past years. That collect rapidly and analyze connection importance information of scientific technique field in this hard fact and offer efficiently timely to investigator processing can say as indispensable indispensability a element in country science technique elevation. Wish to illuminate Specialized Information Center of scientific technique field's role and significance in this hard fact in this research, and examine the role and significance. Together, wish to present way for research direction and Specialized Information Center development by introducing phase thesis and synthetic middle, effort of Korea Institute of Science and Technology Information(KISTI) for special skill development way preparation and study finding for each Specialized Information Center.

• Clinical and Experimental Pediatrics
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• v.59 no.10
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• pp.395-401
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• 2016

Since the outbreak of the enterovirus 71 (EV71) infection in Malaysia in 1997, large epidemics of EV71 have occurred in the Asia-Pacific region. Many children and infants have died from serious neurological complications during these epidemics, and EV71 infection has become a serious public health problem in these areas. EV71 infection causes hand, foot and mouth disease (HFMD) in children, and usually resolves spontaneously. However, EV71 occasionally involves the central nervous system (CNS), and induces diverse neurological complications such as brainstem encephalitis, aseptic meningitis, and acute flaccid paralysis. Among those complications, brainstem encephalitis is the most critical neurological manifestation because it can cause neurogenic pulmonary hemorrhage/edema leading to death. The characteristic clinical symptoms such as myoclonus and ataxia, cerebrospinal fluid (CSF) pleocytosis, and brainstem lesions on magnetic resonance imaging, in conjunction with the skin rash of HFMD and the isolation of EV71 from a stool, throat-swab, or CSF sample are typical findings indicating CNS involvement of EV71 infection. Treatment with intravenous immunoglobulin and milrinone are recommended in cases with severe neurological complications from EV71 infection, such as brainstem encephalitis. Despite the recent discovery of receptors for EV71 in human cells, such as the scavenger receptor B2 and P-selection glycoprotein ligand 1, it is not known why EV71 infection predominantly involves the brainstem. Recently, 3 companies in China have completed phase III clinical trials of EV71 vaccines. However, the promotion and approval of these vaccines in various countries are problems yet to be resolved.

• The Journal of the Convergence on Culture Technology
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• v.2 no.2
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• pp.23-27
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• 2016

'Colored hearing' occurs to those who caused confusion in the visual, auditory path to brain because pruning had not normally done in the growth phase. It is called as 'colored hearing'. 'Colored hearing' is a phenomenon which some people can see colors when they hear sounds. In the interview of video, art experts say that the phenomenon is a natural talents, however professionals in the medical field say that the disorder may be causing a major disruption to daily life. Usually people are unknowingly suffering from synesthesia phenomenon. In this paper, based on the video, we show the phenomenon of 'colored hearing' based on the results of scientific research and on the daily life, and also analyze the video from the viewpoint of the editors and the audience.