• 제목/요약/키워드: Profiling analysis

검색결과 749건 처리시간 0.03초

1H-NMR 스펙트럼의 다변량통계분석을 통한 넙치(Paralichthys olivaceus)의 백신 반응의 지표물질 분석 (Multivariate Analysis on 1H-NMR Spectroscopy of Olive Flounder Paralichthys olivaceus Serum)

  • 조지영
    • 한국수산과학회지
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    • 제45권4호
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    • pp.367-371
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    • 2012
  • To investigate the relationship between metabolic changes in $^1H$-nuclear magnetic resonance (NMR) spectra and fish vaccination, serum was collected from olive flounders treated with a formalin-killed Edwardsiella tarda vaccine and used for $^1H$-NMR metabolite profiling. Principal component analysis and partial least squares were applied to the $^1H$-NMR profile to reduce its complexity and establish class-related clusters. Relative lipid regions were distinguished in vaccinated and non-vaccinated serum. Then, the lipids were extracted from the serum and analyzed. Triolein was identified.

A Comparative Study of Local Features in Face-based Video Retrieval

  • Zhou, Juan;Huang, Lan
    • Journal of Computing Science and Engineering
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    • 제11권1호
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    • pp.24-31
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    • 2017
  • Face-based video retrieval has become an active and important branch of intelligent video analysis. Face profiling and matching is a fundamental step and is crucial to the effectiveness of video retrieval. Although many algorithms have been developed for processing static face images, their effectiveness in face-based video retrieval is still unknown, simply because videos have different resolutions, faces vary in scale, and different lighting conditions and angles are used. In this paper, we combined content-based and semantic-based image analysis techniques, and systematically evaluated four mainstream local features to represent face images in the video retrieval task: Harris operators, SIFT and SURF descriptors, and eigenfaces. Results of ten independent runs of 10-fold cross-validation on datasets consisting of TED (Technology Entertainment Design) talk videos showed the effectiveness of our approach, where the SIFT descriptors achieved an average F-score of 0.725 in video retrieval and thus were the most effective, while the SURF descriptors were computed in 0.3 seconds per image on average and were the most efficient in most cases.

Phospholipid Analysis by Nanoflow Liquid Chromatography-Tandem Mass Spectrometry

  • Moon, Myeong Hee
    • Mass Spectrometry Letters
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    • 제5권1호
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    • pp.1-11
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    • 2014
  • Lipids play important roles in biological systems; they store energy, play a structural role in the cell membrane, and are involved in cell growth, signal transduction, and apoptosis. Phospholipids (PLs) in particular have received attention in the medical and lipidomics research fields because of their involvement in human diseases such as diabetes, obesity, atherosclerosis, and many cancers associated with lipid metabolic disorders. Here I review experimental strategies for PL analysis based on nanoflow liquid chromatography-electrospray ionization-tandem mass spectrometry (nLC-ESI-MSn). In particular, discussed are lipid extraction methods, nanoflow LC separation of PLs, effect of ionization modifiers on the ESI of PLs, influence of chain lengths and unsaturation degree of acyl chains of PLs on MS intensity, structural determination of the molecular structure of PLs and their oxidized products, and quantitative profiling of PLs from biological samples such as tissue, urine, and plasma in relation to cancer and coronary artery disease.

전자분광 화학분석볍을 활용한 표면분석 사례 (Case of Surface Analysis Using The ESCA)

  • 손양수;허진영;이홍기
    • 한국표면공학회:학술대회논문집
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    • 한국표면공학회 2015년도 추계학술대회 논문집
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    • pp.282-282
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    • 2015
  • 전자분광 화학분석(Electron Spectroscopy for Chemical Analysis : ESCA)은 고체표면의 구성원소 및 원소간 화학 결합 상태를 분석할 수 있는 효율적인 방법이다. ESCA 분석은 재료의 극표면층 (약 $20{\sim}100{\AA}$)에 분포되어 있는 원소 및 화학상태를 정성 정량적으로 확인할 수 있다. 또한, $Ar^+$이온을 충돌시켜 재료 표면을 ㎚단위로 식각 할 수 있기 때문에 수직분포 분석(Depth profiling)이 가능하여 나노재료가 활용되는 촉매, 반도체소자 그리고 박막 재료 등의 분석에 유용하게 활용될 수 있다. 이와 같은 분석적 장점에도 불구하고, ESCA 분석은 표면특성 분석에 주로 활용되는 주사전자현미경 및 X-선 미소분석(EDS, WDS) 등에 비하여 폭 넓게 사용되고 있지 못하다.

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Perspectives on the Quality Assurance of Ginseng Products in North America

  • Fitzloff, J.F.;Yat, P.;Lu, Z.Z.;Awng, D.V.C.;Arnason, J.T.;Breemen, R.B.van;Ha, T.ll;Blumenthal, M.;Fong, H.H.S.
    • 고려인삼학회:학술대회논문집
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    • 고려인삼학회 1998년도 Advances in Ginseng Research - Proceedings of the 7th International Symposium on Ginseng -
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    • pp.138-145
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    • 1998
  • A validated and reproducible HPLC method was developed for the profiling and quantitative analysis of ginsenosides in commercial products available in North America. Analysis of 280 Panax ginseng and Panax quinquefolius products showed profiles indicative of the presence of ginsenosides in the majority of these products. However, the quantitative contents of the products vary greatly, not only in products of different formulations, but also of products within each of the fromulations examined.

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기체크로마토그래피법에 의한 타액내 유기산의 신속한 스크리닝 (Rapid Gas Chromatographic Screening of Saliva Samples for Organic Acids)

  • 김경례;김정한;박영준;김정옥
    • 약학회지
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    • 제39권3호
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    • pp.283-288
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    • 1995
  • Rapid gas chromatographic profiling method was applied to saliva from healthy subjects for the analysis of free organic acids. Saliva samples were first saturated with NaHCO$_{3}$ and extracted with diethyl ether. The aqueous phase was solid-phase extracted using Chromosorb P as the adsorbent and diethyl ether as the eluent after the acidification and NaCl saturation, followed by triethylamine treatment. The resulting tiiethylammonium salts of acids were directly converted into stable tert.-butyl-dimethylsflyl derivatives, with subsequent analysis by dual-capiuary column gas chromatography and gas chromatograpy -mass spectrometry. From the ten saliva samples studied, twenty eight free organic acids including various fatty acids, hydroxy acids, dicarboxylic acids, md aromatic acids were tentatively identified. Among the acids identified , the concentration of lactic acid was highest for five saliva samples while $\alpha$-hydroxyisocaproic acid was most abundant for me sample, and succinic acid and glycolic acid for two samples. respectively. When the GC profiles were simplified to the corresponding acid retention index spectra of bar graphical form, they presented characteristic patterns for each individual.

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서비스 온톨로지 기반 SOA 개발 방법론 (SOA Development Methodology Based on Service Ontology)

  • 최고봉;박세권;류승완
    • 한국IT서비스학회지
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    • 제9권2호
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    • pp.193-203
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    • 2010
  • Service-Oriented Architecture (SOA) is a new trend for the design of application architecture to enhance the degree of share and reuse with the concept of service. It comes from the current situation where the business environments are changing rapidly and therefore competitions are getting bitter. To cope with such business challenges, business (and/or applications) architecture needs considerably flexibility and reusability, and that's why SOA is accepted as one of the most effective framework for the business applications in these days. In this paper we propose an analysis and design methodology for the applications of SOA. To implement the proposed methodology, the service ontology needs to be defined first, and the tasks such as service profiling, workflow design and service orchestration need to be followed. To validate the expected effects on flexibility and reusability, the proposed methodology was compared with CBD (Component Based Development).

박용 디젤기관 캠-롤러 접촉부의 응력 해석 (Stress Analysis on the Cam-Roller Contact Parts in a Marine Diesel Engine)

  • 구영필;김형자;임우조;조용주
    • 한국마린엔지니어링학회:학술대회논문집
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    • 한국마린엔지니어링학회 2001년도 춘계학술대회 논문집
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    • pp.168-172
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    • 2001
  • The subsurface stress field beneath the roller due to the lubricant film pressure acting on the roller surface has been calculated. Main purpose of this study in view of engineering is to prove the validity of the numerical profile roller presented by Koo et al who obtained the lubricant film pressure by elastohydrodynamic lubrication analysis on the cam-roller mechanism. The stress field for the numerical profile roller was compared with the one for the existing dub-off profile roller.

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용접연결부의 실제 비드형상을 고려한 노치피로해석법 (Notch Fatigue Analysis Based on the Actual Bead Shape of Welded Joint)

  • 양박달치;박치모
    • 대한조선학회논문집
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    • 제46권4호
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    • pp.417-423
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    • 2009
  • This paper is concerned with the fatigue behaviour of welded joints by the notch stress approach. The actual welded shape is complex and 3-dimensional that may influence greatly the fatigue strength. The purpose of the paper is to present a way of modelling the actual weld bead shape by using a 3-D Laser scanner for experimental models of steel plates with longitudinal fillet welds, and applying its results to a proper notch stress method for the fatigue strength. The present approach to assess the fatigue strength is quite promising with application to a variety of welded joints and effects of weld profiling to fatigue strength.

Multi-omics integration strategies for animal epigenetic studies - A review

  • Kim, Do-Young;Kim, Jun-Mo
    • Animal Bioscience
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    • 제34권8호
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    • pp.1271-1282
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    • 2021
  • Genome-wide studies provide considerable insights into the genetic background of animals; however, the inheritance of several heritable factors cannot be elucidated. Epigenetics explains these heritabilities, including those of genes influenced by environmental factors. Knowledge of the mechanisms underlying epigenetics enables understanding the processes of gene regulation through interactions with the environment. Recently developed next-generation sequencing (NGS) technologies help understand the interactional changes in epigenetic mechanisms. There are large sets of NGS data available; however, the integrative data analysis approaches still have limitations with regard to reliably interpreting the epigenetic changes. This review focuses on the epigenetic mechanisms and profiling methods and multi-omics integration methods that can provide comprehensive biological insights in animal genetic studies.