• Transactions of the Korean Society of Mechanical Engineers A
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• v.34 no.2
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• pp.237-243
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• 2010

This paper presents a study on the helical gear inspection system for application to vehicle transmission gear manufacturing lines. The special gear profile inspection system is not suitable for manufacturing lines due to the measuring time. The master gear method, which was used in this study and compared with the machined gear in the line, is more efficient and economical. In this paper, three helical gear inspection parameters were of concern: nick, run-out, and PCD (pitch circle diameter) error. To evaluate its influence on the accuracy, the gear measuring system was also studied. This system can be useful in practical vehicle transmission gear manufacturing lines, where imported equipment is currently being used.

• Journal of the Korean Society for Precision Engineering
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• v.30 no.3
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• pp.324-330
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• 2013

This paper describes a novel method to surface large optics mirror with an extremely high hardness, which could replace the high cost of the repetitive off-line measurement steps and the large ultra-precision grinding machine with ultra-positioning control of 10 nm resolution. A lot of diamond pellet to be attached on the convex aluminum base consists of a grinding tool for the concave large mirror, and the tool was pressured down on the large mirror blank. The tool motion at an interval on the spiral path was controlled with each feed rate as the dwell time in the conventional computer-controlled polishing. The shape to be surfaced was measured directly by a touch probe on the machine without any separation of the mirror blank. Total 40 iterative steps of the surfacing and measurement could demonstrate the form error of RMS $7.8{\mu}m$, surface roughness of Ra $0.2{\mu}m$ for the mirror blank with diameter of 1 m and spherical radius of curvature of 5400 mm.

• Transactions of the KSME C: Technology and Education
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• v.3 no.3
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• pp.175-181
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• 2015

Because internal space of combat vehicle reachs about $80^{\circ}C$ at high temperature period, Proximity Sensor exposed high temperature and humidity, which has function to sense the distance and transfer signal for control unit, have enlarged sensing distance and finally locked on. Malfunction of sensing itself occur frequently, therefore we carried out cause analysis and improvement. We accomplish improvement activity secondly. Through-out many trial and error, we find out that malfunction of sensor occur at high temperature circumstance. To improve, the another Emitter Coil is added to increase voltage difference and improve sensing accuracy about 5~10 times. And we accomplish design improvement to dull temperature and humity change after increasing molding surface to add vibration and shock resistance. We prove that the improved product do not fail after enduring 136hr at $85^{\circ}C$ temperature and 85% relative humidity circumstance chamber.

• Journal of The Korean Society of Inherited Metabolic disease
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• v.4 no.1
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• pp.5-12
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• 2004

Purpose Phenylketonuria is an inborn error of metabolism, which is inherited as an autosomal recessive trait. PKU is resulting from deficiency of phenylalanine hydroxylase. PAH gene spans about 90 kb on chromosome 12q and comprises 13 exons. In order to define the genetic basis of PKU and the frequencies and distribution of PAH mutations in the Korean population, we analyzed PAH gene in independent 80 patients with PKU. Methods All 13 exons including exon-intron boundaries and 2 kb of 5' upstream region of the PAH gene were analyzed by PCR-direct sequencing methods. Results PAH gene analysis revealed 39 different mutations including 10 novel mutations. The novel mutations consisted of 9 missense mutations (P69S, G103S, N207D, T278S, P281A, L293M, G332V, S391I and A447P) and a novel splice site variant (IVS10-3C>G). R243Q, IVS4-1G>A, and E6-96A>G were the most relevant mutations and they accounted in the whole for 38% of the mutant alleles identified in this study. We also observed that. $BH_4$ responsibility was. associated with genotype of R241C, R53H and R408Q. Conc1ustion Our present study with 80 participants extends the previous results to more comprehensive understanding of PAH allele distribution and frequency in Koreans. Although Korean mutation profile of PAH is similar to those of the nearest oriental populations (Japanese, Chinese, and Taiwanese), several different characteristic features are revealed. The characterization of the genotype-phenotype relationship was also performed. Our data would be very useful information for diagnosis, genetic counseling and planning of dietary and therapeutic strategies in Korean PAH patients.

• Journal of the Institute of Electronics Engineers of Korea SC
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• v.44 no.5
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• pp.55-61
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• 2007

In this paper, we propose a three-dimensional(3D) active shape models for medical image segmentation. In order to build a 3D shape model, we need to generate a point distribution model(PDM) and select corresponding landmarks in all the training shapes. The manual determination method, two-dimensional(2D) method, and limited 3D method of landmark correspondences are time-consuming, tedious, and error-prone. In this paper, we generate a 3D statistical shape model using the 3D model generation method of a distance transform and a tetrahedron method for landmarking. After generating the 3D model, we extend the shape model training and gray-level model training of 2D active shape models(ASMs) and we use the integrated modeling process with scale and gray-level models for the appearance profile to represent the local structure. Experimental results are comparable to those of region-based, contour-based methods, and 2D ASMs.

• Journal of Korea Spatial Information System Society
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• v.2 no.1 s.3
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• pp.91-107
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• 2000

Geographic Information Systems(GISs) generally use a very large amount of spatial data. and are implemented on various software and hardware system. If it is impossible to exchange the spatial data efficiently among the different hardware, software, and operation systems, data sharing will be very difficult and duplicated storage & management of the spatial data will result in a great economic loss. To solve such problems, a national organization established a national standard for GIS and constructed spatial databases at the national level. In Korea, SDTS(Spatial Data Transfer Standard) is selected as a national standard for the common data transfer format. In this paper, we design and implement a SDTS Data Management System which can support display, insertion, update, deletion of SDTS data, extraction and creation of a specified area, error checking and reporting, setting and verification of a SDTS profile through the GUI (Graphic User Interface) environment. Hereafter, as GIS industry is continually activated and a demand for the SDTS data increases, a requirement for analysis and trust of the SDTS data will grow bigger, so the necessity of the SDTS Data Management System developed in this paper will also grow rapidly.

• Journal of Environmental Science International
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• v.12 no.3
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• pp.265-274
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• 2003

The Pasquill-Gifford stability category is a very important scheme of the Gaussian type dispersion model defined the complex turbulence state of the atmosphere by A grade(very unstable) to F grade(very stable). But there has been made a point out that this stability category might decrease the predictability of the model because it was each covers a broad range of stability conditions, and that they were very site specific. The APSM (Air Pollution Simulation Model) was composed of the turbulent parameters, i.e. friction velocity(${\mu}$$\_$*/), convective velocity scale($\omega$$\_$*/) and Monin-Obukhov length scale(Ｌ) for the purpose of the performance increasing on the case of the unstable atmospheric conditions. And the PDF (Probability Density Function)model was used to express the vertical dispersion characteristics and the profile method was used to calculate the turbulent characteristics. And the performance assessment was validated between APSM and EPA regulatory models(TEM, ISCST), tracer experiment results. There were very good performance results simulated by APSM than that of TEM, ISCST in the short distance (<1415 m) from the source, but increase the simulation error(%) to stand off the source in others. And there were differences in comparison with the lateral dispersion coefficient($\sigma$$\_$y/) which was represent the horizontal dispersion characteristics of a air pollutant in the atmosphere. So the different calculation method of $\sigma$$\_$y/ which was extrapolated from a different tracer experiment data might decrease the simulation performance capability. In conclusion, the air pollution simulation model showed a good capability of predict the air pollution which was composed of the turbulent parameters compared with the results of TEM and ISCST for the unstable atmospheric conditions.

• Korean Journal of Biological Psychiatry
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• v.8 no.2
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• pp.226-232
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• 2001

The pharmacotherapy of depression has reduced morbidity and improved outcome for many depressive patients. A wide range of classical and new antidepressants are available for their treatment. However, 30-40% of all patients do not respond sufficiently to the initial treatment and present adverse effects. Pharmacogenetics studies the genetic basis of an individual's ability to respond to pharmacotherapy. Recently, some reports on serotonin transporter gene polymorphisms and their influence on the response to antidepressive therapy provide an interesting diagnostic tool in assessing the chances of response to antidepressants. We also investigated the relationship between serotonin transprter polymorphisms(5-HTTLPR) and the long-term effect of the antidepressant treatment. 128 depressive patients were enrolled into 2nd year study. The therapeutic response of each subset was not different at 8th, 16th week, but the subset with homozygote(l/l) of long variant showed a better therapeutic response to antidepressant than the heterozygote(l/s) of long and short variant, which showed a better therapeutic response than the subset with homozygote (s/s) of short variant at 1st year and 2nd year after the antidepressant treatment. This result shows that the serotonin transporter polymorphisms may be related to the long-term effect of antidepressant treatment. The potential for pharmacogenomics, the use of genetic information to guide pharmacotherapy and improve outcome by providing individualized treatment decisions, has gained increasing attention. pharmacogenomics will contribute to individualize drug choice by using genotype to predict positive clinical outcomes, adverse reactions, and levels of drug metabolism. Personalized medicine, the use of marker-assisted diagnosis and targeted therapies derived from an individual molecular profile, will impact the antidepressant therapy and this approach will replace the traditional trial-and-error practice of medicine.

• Journal of the Korean Society of Manufacturing Technology Engineers
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• v.21 no.3
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• pp.387-393
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• 2012

It is very difficult to determine suitable cutting conditions in order to obtain accurate cutting profiles because machining errors caused by tool deflection depend upon cutting conditions. In this study the relationship between real cutting profiles (inclined shapes and machining errors) and cutting conditions was modeled in order to fabricate draft angle on micro molds. CCD (Central Composite Design) of DOE (Design Of Experiment) and RSM (Response Surface Method) were applied in order to model the relationship between cutting conditions and machining errors. In order to use CCD the range of radial depth of cut was chosen by $10-90{\mu}m$ and the range of feedrate was chosen by 200-300mm/min, and 9 points of cutting conditions were chosen inside determined ranges. Then, actual cutting processes were carried out as respect to 9 points of cutting conditions, draft angles and real cutting profiles were measured on cutting profiles, each response surface function was determined by conducting response surface analysis and the functions were represented by 3-dimensional graphs, contour lines and $101{\times}101$ matrices. Consequently it is possible to determine suitable cutting conditions in order to obtain arbitrary given draft angles and cutting profiles by using modeling. To validate proposed approach in this study suitable cutting conditions were determined by modeling in order to obtain arbitrary given draft angle and cutting profile, and actual cutting processes were carried out. About 95% of good agreement between predicted and measured values was obtained.

• Journal of Korean Society of Transportation
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• v.25 no.5
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• pp.33-42
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• 2007

The current left-turn split model adopted in COSMOS has an inherent limitation when a loop detector in the left-turn lanes was disconnected for a period of time. In this instance, the current model always allocated minimum green time to the left-turn phase, thus optimal split and efficient signal operation for the intersection was not guaranteed. In this paper, four mathmatical models using detector information of the intersection and four empirical models using historical profiles were developed and investigated for different traffic conditions to improve the operational efficiency of the intersection. From the model evaluation test, the empirical model using a four-week historical profile produced the least error among the eight models investigated. NETSIM simulation test results also showed that the proposed model could give significantly reduced delay time as compared to the current model. From these results, the operational efficency of the signalized intersections under the real-time control can be greatly improved by using the model proposed in case of the left-turn detector failure.