• Industrial Engineering and Management Systems
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• 제14권4호
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• pp.401-412
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• 2015

In this paper, we present a modeling approach to production planning for an actual production line and a heuristic method. We also illustrate the successful implementation of the proposed method on the production line. A heuristic algorithm called the push-back algorithm was designed for a single machine earliness/tardiness production planning with distinct due date. It was developed by combining a minimum slack time rule and shortest processing time rule with a push-back procedure. The results of a numerical experiment on the heuristic's performance are presented in comparison with the results of IBM ILOG CPLEX. The proposed algorithm was applied to an actual case of production planning at Woongjin Chemical, a leading manufacturer of filter products in South Korea. The seven-month execution of our algorithm led to a 24.5% decrease in the company's inventory level, thus demonstrating its practicality and effectiveness.

• 대한한방부인과학회지
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• 제18권4호
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• pp.54-71
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• 2005

Purpose : The purpose of this research was to investigate the effects of Saurui Herba Seu Rhizoma(SHSR) on Anti-inflammatory properties in Raw264.7 cell line and murine models of inflammation. Methods : To investigate the effects of Saurui Herba Seu Rhizoma(SHSR) on anti-inflammation, we study cytotoxicity effects of SHSR on Mouse Lung Fibroblast Cells and Peritoneal Macrophages, Inhibitory effects of SHSR on the nitric oxide (NO) release, the ROS production, and the interleukin-6 production. Results : The cytotoxicity of SHSR on mouse lung fibroblast Cells and Raw264.7 cell line was not observed. SHSR in RAW264.7 cell line inhibited $IL-1{\beta}$, IL-6 mRNA gene expression depending upon the concentrations of extract and inhibited IL-18 mRNA gene expression at 100 ${\mu}g/ml$ of extract. SHSR in RAW264.7 cell line inhibit COX-2 mRNA gene expression at 100, 10 ${\mu}g/ml$ of extract. SHSR in RAW264.7 cell line inhibited NOS-II mRNA gene expression depending upon the concentrations of extract. SHSR in RAW264.7 cell line didn't inhibit $TNF-{\alpha}$ mRNA　gene expression. SHSR in RAW264.7 cell line decreased IL-6 production depending　upon the concentrations of extract. SHSR in RAW264.7 cell line decreased $ITNF-{\alpha}$ production according to the concentrations of extract. SHSR in RAW264.7 cell line inhibited NO release specially SHSR 100, 10 ${\mu}g/ml$ concentrations of extract. SHSR inhibit ROS production depending upon the concentrations of extract. Conclusion : These results suggest that SHSR can be used treating a lot of women disease caused by inflammation.

• Industrial Engineering and Management Systems
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• 제8권3호
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• pp.131-138
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• 2009

The variable sampling inspection scheme with screening for the purpose of assuring the upper limit of maximum expected surplus loss after inspection has been proposed. In this inspection scheme, it has been assumed that a product lot consists of products manufactured through a single production line and lot quality characteristics follow a normal distribution. In the previous literature with respect to inspection schemes, it has been commonly assumed that lot quality characteristics obey a single normal distribution under the condition that all products are manufactured in the same condition. On the other hand, the production line is designed in order that the workload of respective processes becomes uniform from the viewpoint of line balancing. One of the solutions for the bottleneck process is to arrange the workshops in parallel. The lot quality characteristics from such a production line with the process consisting of some parallel workshops might not follow strictly the single normal distribution. Therefore, we expand an applicable scope of the above mentioned variable sampling inspection scheme with screening in this article. Concretely, we consider the variable sampling inspection with screening for the purpose of assuring the upper limit of average outgoing surplus quality loss in the production lots when the lot quality follows the mixed normal distribution.

• 한국시뮬레이션학회논문지
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• 제5권2호
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• pp.1-12
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• 1996

Utilizing the simulation approaches, the dynamic production scheduling system FOLS(Flexible flowshop On-Line Simulation) is developed under the flexible flowshop environment. When an interruption such as machine failure/recovery is occurred at the shop floor, the FOLS system performs evaluations for job selection rule oriented alternatives, and generates a dynamic production schedule based on the collected current shop floor data. For the case study, the FOLS system is applied to the printed circuit card assembly(PCCA) line and simulation results are reported.

• 산업경영시스템학회지
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• 제18권34호
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• pp.115-121
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• 1995

The objective of this study is to develope an effectiveness measurement technique for U-shaped JIT production line by computer simulation. A small and medium sized automobile brake master cylinder manufacturing plant is studied for productivity improvement The production line is analysed and improved by applying Low Cost Automation, special jigs and fixtures, and facilities layout changes. An experimental simulation model is built using SIMAN(SIMulation ANalysis) simulation software for the production system analysis.

• BMB Reports
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• 제57권2호
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• pp.86-91
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• 2024

The fatty acids content of castor (Ricinus communis L.) seed oil is 80-90% ricinoleic acid, which is a hydroxy fatty acid (HFA). The structures and functional groups of HFAs are different from those of common fatty acids and are useful for various industrial applications. However, castor seeds contain the toxin ricin and an allergenic protein, which limit their cultivation. Accordingly, many researchers are conducting studies to enhance the production of HFAs in Arabidopsis thaliana, a model plant for oil crops. Oleate 12-hydroxylase from castor (RcFAH12), which synthesizes HFA (18:1-OH), was transformed into an Arabidopsis fae1 mutant, resulting in the CL37 line producing a maximum of 17% HFA content. In addition, castor phospholipid:diacylglycerol acyltransferase 1-2 (RcPDAT1-2), which catalyzes the production of triacylglycerol by transferring HFA from phosphatidylcholine to diacylglycerol, was transformed into the CL37 line to develop a P327 line that produces 25% HFA. In this study, we investigated changes in HFA content when endogenous Arabidopsis PDAT1 (AtPDAT1) of the P327 line was edited using the CRISPR/Cas9 technique. The successful mutation resulted in three independent lines with different mutation patterns, which were transmitted until the T4 generation. Fatty acid analysis of the seeds showed that HFA content decreased in all three mutant lines. These findings indicate that AtPDAT1 as well as RcPDAT1-2 in the P327 line are involved in transferring and increasing HFAs to triacylglycerol.

• 대한산업공학회지
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• 제24권1호
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• pp.105-113
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• 1998

This paper deals with a production line which consists of two production stages that are separated by a finite storage buffer. The inventory level in the storage buffer controls the production rate of the preceding stage. That is, the production rate becomes high (low) when the buffer inventory is low (high). We analyze the system characteristics utilizing the Markov process theory and then find an optimal control policy which maximizes a given system profit function. Also, a sensitivity analysis is made to examine the effects of various system parameters on the system performances.

• 한국의류학회지
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• 제25권1호
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• pp.103-114
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• 2001

In Korean clothing industry, most of the womens wear is manufactured by subcontractors. Because womens fashion is getting more rapidly changing, subcontractors production run of each orders is getting shorter too. Also the volume of each order is quite small compare to mens or childrens. So subcontractors are always in a hurry to adjust their production capacity to new order. Therefore they cannot afford to plan production line and allocate works efficiently enough to manufacture competitive products in terms of cost, lead time, as well as quality. The purpose of this study is to suggest a production planning model for womens apparel manufacture, which are relevant to the situation of Korean clothing industry.

• 한국시뮬레이션학회논문지
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• 제22권2호
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• pp.93-100
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• 2013

다품종 소량생산이 보편화 되면서 하나의 생산라인에서 여러 종류의 제품을 교대로 생산하는 혼류생산방식이 보편화 되었다. 하지만 흐름라인 방식의 혼류생산에서는 필연적으로 작업장 간의 공정시간 불균형이 존재한다. 따라서 이러한 공정불균형에 의한 대기의 낭비를 최소화하기 위하여 기존의 흐름생산방식에서 셀생산방식으로 전환하는 시도가 빈번하게 발생한다. 본 논문에서는 굴삭기 부품을 생산하는 혼류흐름라인 방식의 자동화 로봇 용접라인을 FMC 개념의 직선형 셀방식으로 전환하는 과정에서 타당성 검토를 위해 시뮬레이션을 수행한 사례연구 결과를 소개한다. 분석결과 26.7%의 생산량 증가와 55% 이상의 리드타임 감소효과가 예상되었다. 또한 향후 제품 생산비율의 변화에 따른 민감도분석을 수행하였다.

• 한국공작기계학회논문집
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• 제16권5호
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• pp.162-165
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• 2007

TFT-LCD process has two advantages as compared with the semiconductor-process. It is that cycle time is short and number of the final products are small. But it needs complicated inspection / assembly line to be treated manually and much higher labor costs in the TFT-LCD process. Also, It is necessary to build PICS(Production Information and Control System) which is automated and intelligent. In this paper, an automated process of LCD module assembly line that can increase productivity and reduce the cost of production to strengthen the competitiveness corresponding with global market is planned in comparison with its manual/semi-auto. It is noted that The automated line for COG$\sim$FOG process replacing with the existing facilities had the following effects; the productivity is increased to about 1.5 times and labor cost reduced 85%. In addition, whole assembly line can be short and simple.