• Title/Summary/Keyword: Product Risk

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Trend of standardization in the field of Industrial Security through ISO/TC 292 (ISO/TC 292에 의한 산업보안 분야 국제표준화의 동향)

  • Park, Hyeon-Ho
    • Korean Security Journal
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    • no.48
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    • pp.79-111
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    • 2016
  • This study aims at analyzing the global trend of standardization in the field of Industrial Security through ISO/TC 292. It covers broad areas from risk management for industrial property protection and loss prevention through supply chain security, product and document fraud and counterfeiting countermeasures and control and community resilience. It also explores the historical background of the standardization in the security field, how ISO TC 292 came out as a leading group in order to standardize relevant security management systems. TC 292 deals with terminology, general security-related standards and supply chain security management. One of the major findings from this analysis is that security targets and threats are diversified and so organizations like enterprises should have proper flexibility to adapt themselves to new security environment and take appropriate resilience system to cope with the threats and incidents. Also the ISO standardization requires public or private entities to take holistic approaches in security management. Finally, it was found that South Korea has to prepare for this global trend of standardization in this field so that ISO certification market demand and the requirements for transnational trades can be well met.

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Comparison about adverse drug reaction report forms among Asian's countries using herbal medicine (한약을 사용하는 아시아권 국가의 유해사례 보고 양식에 관한 비교 연구)

  • Sun, Seung-Ho;Lee, Eun-Kyoung;Jang, Bo-Hyoung;Park, Sunju;Go, Ho-Yeon;Jeon, Chan-Yong;Ko, Seong-Gyu
    • Journal of Society of Preventive Korean Medicine
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    • v.19 no.3
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    • pp.91-102
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    • 2015
  • Objective : The purpose of this study is to find out the possibility of application to herbal medicine's report form for adverse drug reaction (ADR) by reviewing and analyzing Asian countries's ADR report forms. Method : We investigated, compared, and analyzed ADR report forms (ADR-RF) of Asian countries's ADR institutions (ACAI), such as, Korea institute of drug safety & risk management and Dongguk university Ilsan oriental hospital (DUIOH) in Korea, national center for ADR monintoring (NCAM) in China, pharmaceuticals and medical devices agency (PMDA) in Japan, Ministry of Health and Welfare (MOHW) in Taiwan, and drug office, department of health, the government of the Hong Kong special administrative region (GHKSAR) in Hong Kong. Results : ADR-RF for ACAI included common contents, such as, patients information (name(initial), gender, age, weight), adverse event (AE)'s report information (Recognition and report for AE occurrence, first or follow up report, Severe AE), the detailed information of AE (the title of AE, onset & closing date of AE symptoms, the progress & results detailed test of AE), the information of AE's medicine (the types of medicine, product name, ingredient name, suspected or combination drug, single dose & frequency, dosage form, administration route, dealing for AE-suspected medicine), and AE reporter's information (reporter's information, institution's information). Taiwan had ADR-RF and the department exclusively for herbal medicine (HM), but others (except DUIOH) had not only no ADR report form but also contents for HM. Conclusion : ADR-RF for HM have to include the common contents of ACAI at least, as well as HM information related to ADR, such as the title, composition and types of HM, history related to HM's ADR, and the contents of drug-induced liver injury and so on. In addition, the main department of government for HM's ADR will be needed.

Current status of Atomic and Molecular Data for Low-Temperature Plasmas

  • Yoon, Jung-Sik;Song, Mi-Young;Kwon, Deuk-Chul
    • Proceedings of the Korean Vacuum Society Conference
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    • 2015.08a
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    • pp.64-64
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    • 2015
  • Control of plasma processing methodologies can only occur by obtaining a thorough understanding of the physical and chemical properties of plasmas. However, all plasma processes are currently used in the industry with an incomplete understanding of the coupled chemical and physical properties of the plasma involved. Thus, they are often 'non-predictive' and hence it is not possible to alter the manufacturing process without the risk of considerable product loss. Only a more comprehensive understanding of such processes will allow models of such plasmas to be constructed that in turn can be used to design the next generation of plasma reactors. Developing such models and gaining a detailed understanding of the physical and chemical mechanisms within plasma systems is intricately linked to our knowledge of the key interactions within the plasma and thus the status of the database for characterizing electron, ion and photon interactions with those atomic and molecular species within the plasma and knowledge of both the cross-sections and reaction rates for such collisions, both in the gaseous phase and on the surfaces of the plasma reactor. The compilation of databases required for understanding most plasmas remains inadequate. The spectroscopic database required for monitoring both technological and fusion plasmas and thence deriving fundamental quantities such as chemical composition, neutral, electron and ion temperatures is incomplete with several gaps in our knowledge of many molecular spectra, particularly for radicals and excited (vibrational and electronic) species. However, the compilation of fundamental atomic and molecular data required for such plasma databases is rarely a coherent, planned research program, instead it is a parasitic process. The plasma community is a rapacious user of atomic and molecular data but is increasingly faced with a deficit of data necessary to both interpret observations and build models that can be used to develop the next-generation plasma tools that will continue the scientific and technological progress of the late 20th and early 21st century. It is therefore necessary to both compile and curate the A&M data we do have and thence identify missing data needed by the plasma community (and other user communities). Such data may then be acquired using a mixture of benchmarking experiments and theoretical formalisms. However, equally important is the need for the scientific/technological community to recognize the need to support the value of such databases and the underlying fundamental A&M that populates them. This must be conveyed to funders who are currently attracted to more apparent high-profile projects.

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A Study of Adverse Health Symptoms of Spray Painters Using Isocyanates(HDI) (분사페인트에 의한 이소시안화물의 노출이 건강에 미치는 영향에 관한 연구)

  • Lee, So-Gil;Pisaniello, Dino;Lee, Nae-Woo
    • Journal of the Korean Society of Safety
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    • v.23 no.3
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    • pp.79-86
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    • 2008
  • In the manufacturing industries using HDI(hexamethylene diisocyanate) product hardeners, exposure to HDI is common to spray painters in terms of inhalation and dermal or ocular contact. Due to a lack of information for spray painters in automobile and furniture industries, a questionnaire survey was conducted for the prevalence of adverse health symptoms(33 spray painters and an unexposed group n = 91) to assess the importance of personal controls. Despite the small sample size, common health symptoms were reported, such as skin symptoms(dry cracked skin-61% and dermatitis/skin irritation-33%) and respiratory symptoms(phlegm-49%, asthma-21%). In addition, other adverse health symptoms were reported, such as skin rash(12%), cough(39%), shortness of breath with wheezing(30%), chest tightness and difficulty in breathing(30%). No significant eye symptoms were reported. It was founded that the adverse health symptoms reported in this study were related to poor personal work practices and inappropriate PPE use. Therefore, appropriate personal controls like PPE use, work practices, regular training and education are suggested to minimize the risk of health symptoms. In addition, medical examination will also be suggested for individual health effects.

Effects of Heat Treatment on Protein Quality as Lysine Damage (열처리가 Lysine 손상에 의한 단백질의 품질에 미치는 영향)

  • 이경혜
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.24 no.5
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    • pp.816-828
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    • 1995
  • During the industrial preparation and the storage of foods, the side chain of some protein-bound amino acids can react chemically each other or with other molecules present in the food. The following reactions have been described : destruction of amino acids, racemization, protein-protein interactions, reactions of proteins with reducing sugars, oxidizing agents, or polyphenols. Apart from total destruction, the main reacitons are the forming of Maillard reactions products(e.g. fructoselysine) and the crosslinking with other amino acids in the same or in another protein molecule(e.g. lysinoalanine). The most often involved amino acid is lysine because of its free functional ${\varepsilon}-amino$ acid group. Generally derivatives of amino acids or crosslinks in polypeptides influence the bioavailability and the overall digestibility of the protein. This work reviews the technological, analytical, nutritional, and physiological problems related to the formation of fructoselysine and lysinolalnine in human foods, and evaluates the possible health risk for humans. A summary of the available information is of help in considering whether or not the presence of fructoselysine/lysinoalanine in foods represents a danger to man. The reduction in protein quality through these reactions is not a problem for the general population, but it is extremely important in infant foods, since infants are often nourished with a limited number of food product(e.g. formular foods) which are sensitive to the Mailard reaction.

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Performance Analysis on the Reduction of Drowning Accident Using Buoyancy Bag (부력가방의 익사사고 저감성능 분석)

  • Choi, Kwang Won;Cho, Woncheol;Lee, Taeshik
    • Journal of Korean Society of societal Security
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    • v.3 no.2
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    • pp.33-39
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    • 2010
  • This study is to reduce the rate of drowning accident by using of buoyancy bag. People are exposed to the high risk of drowning accident when they have water leisure activities due to the lack of safety mind-set and shortage of safety products. In case of drowning accident, the rescue action is normally depending on the other people's assistance. Therefore, rescue activities which relyn the people doesn't improve the ratio of survival in the drowning accidents. The submarine specialists should use the buoyancy products to rescue the people in the drowning accident. The citizen can carry portable buoyancy product in the automobile as well as by hands anywhere and anytime. It will be effective rescue tool to save his/her life in the emergency. In addition, it will contribute to rescue other's life because it can be used immediately. There are 3 positive characteristics on the buoyancy bag. First, it is convenience. Documents and other stuffs can be kept in the bag. Second is safety. The material of buoyancy is placed in the inner of the bag. It is possible to float the person whose weight is 90 kg. Lastly, it is durability. It can be used long-term because the outer of the bag is made of anti-water material and anti-water zipper. As a result of performance analysis, it is evident that the buoyancy bag can be used to rescue the people in the drowning accident as a indirect rescue tool compared with the current other rescue products. It is recommended that the design of outer box and performance of buoyancy are required to be improved in order to contribute more to rescue people in the accident.

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Consumption of Water-Soluble Egg Yolk Extract on Growth Rate, Changes in Blood Cholesterol Levels, and Immune Modulation in BALB/c Mice

  • Lee, Won-Young;Lee, Ran;Kim, Hee-Chan;Lee, Kyung-Hoon;Noh, Kyung Sook;Kim, Hyoun Wook;Kim, Ji-Hyuk;Ahn, Dong-Uk;Jang, In-Surk;Jang, Aera;Lee, Hoon-Taek;Song, Hyuk
    • Food Science of Animal Resources
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    • v.33 no.5
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    • pp.587-594
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    • 2013
  • Egg consumption has been limited to avoid cardiovascular diseases such as atherosclerosis and hyperlipidemia, because the yolk contains high levels of cholesterol. This study was conducted to evaluate the effect of the water-soluble component of egg-yolk on the growth efficiency, immune modulation, and changes in serum lipid levels in BALB/c mice. A total 5 wk old 120 BALB/c male mice were divided into 4 groups and were fed 0, 2, 10, and 20 mg/d water-soluble egg yolk extract (WSEYE) for 5 wk. Water-soluble egg yolk extract (WSEYE) uptake resulted in a significant reduction in daily weight gain and feed efficiency rate (FER). The mouse groups treated with 2 and 20 mg/d WSEYE showed a significant increase in populations of monocytes at the third wk and B-lymphocyte activity at the fifth wk. In addition, WSEYE uptake did not influence serum immunoglobulin E levels. In serum lipid-profile studies, treatment of WSEYE did not alter total cholesterol and low-density lipoprotein levels; however, blood triglyceride levels were significantly diminished in mice treated with 2 mg/d at the third wk (p<0.05), and the level of high-density lipoprotein was significantly increased in the mice group treated with 2 and 10 mg/d WSEYE after 5 wk (p<0.05). Taken together, the data demonstrate the beneficial effects of WSEYE in the diet on immune modulation and serum lipid profiles in mouse models; therefore, this study suggests that ingestion of water-soluble fraction of egg yolk might not be related to the increased risk of heart disease, but can be an excellent candidate for maintaining health.

Safety Evaluation of Water-soluble Chromium in Makeup Products (메이크업 화장품에서 수용성 크롬의 안전성 평가)

  • Jeong Hye-Jin;Joo Kyung-Mi;Kim Young-So;Park Jeong-Eun;Park Jin-Hee
    • Toxicological Research
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    • v.21 no.1
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    • pp.15-21
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    • 2005
  • There is now a growing concern about the possible toxicity of heavy metals in cosmetics. Heavy metals can be used as cosmetic ingredients or may be present as low level impurities in some of the raw materials. Chromium derivatives are used as pigments in cosmetics. Chromium is essential and toxic trace elements. Chromium may cause skin allergy. However, the regulations related to cosmetic products give no limit values for Chromium. Hexavalent chromium is significantly more toxic than trivalent chromium. Hexavalent chromium may present a carcinogenic risk at high concentrations. Therefore, it is important to consider oxidation state of chromium when analyze chromium. The purpose of this study is to determine the concentrations of water-soluble trivalent and hexavalent chromium in samples of makeup products, and to assess the safety of cosmetics on the basis of animal sensitization tests using guinea pig. The present study of chromium in 48 makeup products of 12 manufacturers provides a basis for assessing safety of makeup products. Water-soluble hexavalent chromium was not detected in any product. Water-soluble trivalent chromium was detected in only 9 eye shadows out of 48 makeup products, and could not be quantified 3 out of 9 eye shadows. The highest level of water-soluble trivalent chromium was about 10 mg/kg in spite of 90,000 mg/kg of total chromium. The results of animal sensitization tests show that 200 mg/kg of trivalent chromium and 5 mg/kg of hexavalent chromium have no harmful effect. No cross-reaction among these metals was found. Accordingly, the concentrations of water-soluble chromium in makeup products seemed to be safe. The overall results indicate that chromium in cosmetics probably have no significant toxicological effects. However, It is necessary to set guidelines on the maximum permissible concentration of water-soluble chromium in cosmetics.

NIR-TECHNOLOGY FOR RATIONALE SOIL ANALYSIS WITH IMPLICATIONS FOR PRECISION AGRICULTURE

  • Stenberg, Bo
    • Proceedings of the Korean Society of Near Infrared Spectroscopy Conference
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    • 2001.06a
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    • pp.1061-1061
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    • 2001
  • The scope of precision agriculture is to reach the put up cultivation goals by adjusting inputs as precise as possible after what is required by the soil and crop potentials, on a high spatial resolution. Consequently, precision agriculture is also often called site specific agriculture. Regulation of field inputs “on the run” has been made possible by the GPS (Geographical Position System)-technology, which gives the farmer his exact real time positioning in the field. The general goal with precision agriculture is to apply inputs where they best fill their purpose. Thus, resources could be saved, and nutrient losses as well as the impact on the environment could be minimized without lowering total yields or putting product quality at risk. As already indicated the technology exists to regulate the input based on beforehand decisions. However, the real challenge is to provide a reliable basis for decision-making. To support high spatial resolution, extensive sampling and analysis is required for many soil and plant characteristics. The potential of the NIR-technology to provide rapid, low cost analyses with a minimum of sample preparation for a multitude of characteristics therefore constitutes a far to irresistible opportunity to be un-scrutinized. In our work we have concentrated on soil-analysis. The instrument we have used is a Bran Lubbe InfraAlyzer 500 (1300-2500 nm). Clay- and organic matter-contents are soil constituents with major implications for most properties and processes in the soil system. For these constituents we had a 3000-sample material provided. High performance models for the agricultural areas in Sweden have been constructed for clay-content, but a rather large reference material is required, probably due to the large variability of Swedish soils. By subdividing Sweden into six areas the total performance was improved. Unfortunately organic matter was not as easy to get at. Reliable models for larger areas could not be constructed. However, through keeping the mineral fraction of the soil at minimal variation good performance could be achieved locally. The influence of a highly variable mineral fraction is probably one of the reasons for the contradictory results found in the literature regarding organic matter content. Tentative studies have also been performed to elucidate the potential performance in contexts with direct operational implications: lime requirement and prediction of plant uptake of soil nitrogen. In both cases there is no definite reference method, but there are numerous indirect, or indicator, methods suggested. In our study, field experiments where used as references and NIR was compared with methods normally used in Sweden. The NIR-models performed equally or slightly better as the standard methods in both situations. However, whether this is good enough is open for evaluation.

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Probe Study on the Failure Factors of Venture Companies (벤처기업의 부실요인에 대한 탐색적 연구)

  • Lee, Hoon;Hong, Jae-Bum
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.12 no.1
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    • pp.25-31
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    • 2017
  • The objective of this study is to find the failure factors of venture companies. We analyze 210 troubled venture companies, all of which have been under guarantee from the Korea Technology Finance Corporation over the last three years. Methods of analysis for failure factors are as follows. First, we categorize the failure factors into the four different types based on growth and profitability indicators in the financial statements of targeted venture companies. Then we analyzed the failure factors of the subject companies based on the troubled guarantee reports made by the Korea Technology Finance Corporation. If a venture company under its guarantee program falls into insolvency, the Korea Technology Finance Corporation make the troubled guarantee report to find out the failure factors and evaluate the recovery potentials. We identify 374 failure factors of venture companies through the analysis. The most prominent among them are deteriorating of business environments (79 factors) and decreasing or withdrawing orders from major suppliers (54 factors) due to bankruptcies or change in business plans. They are followed by slowing collection of accounts receivable (31 factors), dropping or frozen product price (24 factors) due to intensifying competition and escalating pressures from major suppliers, rising raw material costs both at home and abroad (21 factors). In addition, the nuclear power plant disaster in Japan, shut-down of the Kaesong Industrial Complex and subsequent lawsuits, delay in technology development projects, high cost-low efficiency management structure, etc., are also revealed as new factors causing trouble for venture companies.

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