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A Study of Adverse Health Symptoms of Spray Painters Using Isocyanates(HDI)  

Lee, So-Gil (Discipline of Public Health, University of Adelaide, South Australia)
Pisaniello, Dino (Discipline of Public Health, University of Adelaide, South Australia)
Lee, Nae-Woo (Faculty of Safety Engineering, Pukyong National University)
Publication Information
Journal of the Korean Society of Safety / v.23, no.3, 2008 , pp. 79-86 More about this Journal
Abstract
In the manufacturing industries using HDI(hexamethylene diisocyanate) product hardeners, exposure to HDI is common to spray painters in terms of inhalation and dermal or ocular contact. Due to a lack of information for spray painters in automobile and furniture industries, a questionnaire survey was conducted for the prevalence of adverse health symptoms(33 spray painters and an unexposed group n = 91) to assess the importance of personal controls. Despite the small sample size, common health symptoms were reported, such as skin symptoms(dry cracked skin-61% and dermatitis/skin irritation-33%) and respiratory symptoms(phlegm-49%, asthma-21%). In addition, other adverse health symptoms were reported, such as skin rash(12%), cough(39%), shortness of breath with wheezing(30%), chest tightness and difficulty in breathing(30%). No significant eye symptoms were reported. It was founded that the adverse health symptoms reported in this study were related to poor personal work practices and inappropriate PPE use. Therefore, appropriate personal controls like PPE use, work practices, regular training and education are suggested to minimize the risk of health symptoms. In addition, medical examination will also be suggested for individual health effects.
Keywords
isocyanate; questionnaire; health symptom; spray painter; crash repair shops; furniture industry;
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Times Cited By KSCI : 1  (Citation Analysis)
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1 Talini D., Monteverdi A., Benvenuti A., Petrozzino M., Di Pede F., Lemmi M., Carletti A., Macchioni P., Serretti N., Viegi G. and Paggiaro P., Asthma- like symptoms, atopy, and bronchial responsiveness in furniture workers, Occup. Environ. Med., Vol. 55, No. 11, 786-791, 1998   DOI
2 Karol M.H., Respiratory effects of inhaled isocyanates, CRC Crit. Rev. Toxicol., Vol. 16, 349-379, 1986   DOI
3 Liu Y.C., Sparer J., Woskie S.R., Cullen M.R., Chung J.S., Holm C.T. and Redlich C.A., Qualitative assessment of isocyanate skin exposure in auto body shops: A pilot study, Am. J. Ind. Med., Vol. 37, 265- 274, 2000   DOI   ScienceOn
4 HSE, Occupational Asthma - Causal agents for occupational asthma, Health & Safety Executive, UK, Updated 15th Nov. 2007, URL: http://www.hse. gov.uk/statistics/causdis/asthma/agents.htm, 2007
5 Gun R.T., Langley A., Dundas S.J. and McCaul K., The Human Cost of Work-Occupational Respiratory Disease, 2nd Ed., ISBN 0-7308-4858-2, SA Health Commission, Adelaide, 1996
6 Banks D.E., Butcher B.T. and Salvaggio J.E., Isocyanate- induced respiratory disease, Ann. Allergy, Vol. 57, 389-398, 1986
7 Hagmar L., Nielsen J. and Skerfving S., Clinical features and epidemiology of occupational obstructive respiratory disease caused by small molecular weight organic chemicals, Monogr. Allergy., Vol. 21, 42-58, 1987
8 Cushmac M., Difiore D. and Hetfield C., New Chemical Environmental Technology Initiative- Automotive Refinishing Industry Isocyanate Profile, U.S. Environmental Protection Agency(EPA), SAIC Project No. 01-1029-07-8088, 1997
9 Pisaniello D., Edwards J., Cattani M., and Tkaczuk M., Exposure and Health Effects Among Pest Control Operators Using the Insecticide Chloropyrifos - Report for the National Occupational Health and Safety Commission, The University of Adelaide, Adelaide, 2000
10 Talini D., Monteverdi A., Benvenuti A., Petrozzino M., Di Pede F., Lemmi M., Carletti A., Macchioni P., Serretti N., Viegi G. and Paggiaro P., Asthma- like symptoms, atopy, and bronchial responsiveness in furniture workers, Occup. Environ. Med., Vol. 55, No. 11, 786-791, 1998   DOI
11 Mohanu N., A Follow-up Study of Isocyanate Exposures and Health Outcomes in Automobile Spray Painting Workshops, Master of Public Health Thesis, The University of Adelaide, Department of Community Medicine(Unpublished), 1996
12 Heitbrink W.A., Cooper TC., Edmonds M.A., Bryant C.J. and Ruch W.E., In-DEPTH Survey Report- Control Technology for Autobody Repair and Painting Shops at Jeff Wyler Autobody Shop, Batavia, Ojio, Occupational Safe & Health Administration(OSHA), U.S. Department of Labor, Report No. ECTB 179-14a, 1993
13 Malo J.L., Ouitmet G., Cartier A., Levits D. and Zeiss R., Combined alveolitis and asthma due to hexamethylwene diisocyanate, with demonstration of crossed respiratory and immunologic reactivities to diphenylmethane diiso- cyanate, J. Allergy Clin. Immunol., Vol. 72, No. 4, 413-419, 1983   DOI
14 ATSDR, Toxicological Profile for Hexamethylene Diisocyanate(HDI), CAS#822-06-0, Agency for Toxic Substances and Disease Resitry, 1998
15 Liu, Y, Bello, D, Sparer, JA, Stowe, MH, Gore, RJ, Woskie, SR, Cullen, MR and Redlich, CA. Skin exposure to aliphatic polyisocyanates in the auto body repair and refinishing industry: a qualitative assessment. Ann Occup Hyg, Vol. 51, 429-439, 2007   DOI   ScienceOn
16 Fleiss J.L., Statistical Methods for Rates and Proportions, 2nd Edn., John Wiley, New York, 30-31, 1981
17 Mobay Corporation, 21-Day Inhalation Toxicity Study with Hexamethylene Diisocyanate(HDI) in Rats, EPA/OTS doc #86-870001230, 1984
18 Mobay Corporation, Chronic Inhalation Toxicity and Oncogenicity Study in Rats, EPA/OTS Doc. No. 86-900000055, 1989
19 Liu Y., Berode M., Stowe M.H., Holm C.T., Walsh F.X., Slade M., Boeniger M.F. and Redlich C.A., Urinary hexane diamine to assess respiratory exposure to hexamethylene diisocyanate aerosol: A human inhalation study, Int. J. Occup. Environ. Health, Vol. 10, No. 3, 262-271, 2004   DOI
20 Redlich C.A., Stowe M.H., Coren B.A., Wisnewski A.V., Holm C.T. and Cullen M.R., Diisocyanateexposed auto body shop workers: A one-year follw- up, Am. J. Ind. Med., Vol. 42, No. 6, 511-518, 2002   DOI   ScienceOn
21 Heitbrink W.A., Cooper TC. and Edmonds M.A., Control of paint overspray in Autobody repair shops, Am. Ind. Hyg. Assoc. J., 56, 1023-1032, 1995   DOI   ScienceOn
22 Randolph B.W., Lalloo U.G., Gouws E. and Colvin M.S., An evaluation of the respiratory health status of automotive spray-painters exposed containing hexamethylene diisocyanates in the greater durban area, S. Afr. Med. J., Vol. 87, No. 3, 318-323, 1997
23 Liu, Y, Bello, D, Sparer, JA, Stowe, MH, Gore, RJ, Woskie, SR, Cullen, MR and Redlich, CA. Skin exposure to aliphatic polyisocyanates in the auto body repair and refinishing industry: a qualitative assessment, Ann Occup Hyg., Vol. 51, 429-439, 2007   DOI   ScienceOn
24 Cooper T.C., Heitbrink W.A., Edmonds M.A., Bryant C.J. and Ruch W.E., In-DEPTH Survey Report- Control Technology for Autobody Repair and Painting Shops, Occupational Safe & Health Administration( OSHA), U.S. Department of Labor, Report No. ECTB 179-15a, 1993
25 McCammon C., NIOSH Health Hazard Evaluation, Occupational Safety & Health Administration(OSHA), U.S Department of Labor, Report No. HETA 95- 0405-2600, 1996
26 Pisaniello D. and Muriale L., The use of isocyanate paints in auto refinishing: A survey of isocyanate exposure and related work practices in South Australia, Ann. Occup. Hyg., Vol. 33, No. 4, 563-572, 1989a   DOI   ScienceOn
27 Baur X., Marek W., Ammon J. and Czuppon A.B., Respiratory and other hazards of isocyanates, Int. Arch. Occup. Environ. Health., Vol. 66, 141-152, 1994   DOI
28 Cullen M.R., Redlich C.A., Beckett W.S., Weltmann B., Sparer J., Jackson G., Ruff T., Rubinstein E. and Holden W., Feasibility study of respiratory questionnaire and peak flow recordings in Autobody shop workers exposed to Isocyanate- containing spray paint: Observation and limitations, Occup. Med., Vol. 46, No. 3, 197-204, 1996   DOI   ScienceOn
29 Lee, S. G., Lee, N. W., Pisaniello, D., Evaluation of Exposure to Isocyanate Used in Furniture Industry, J. of Korean Society of Safety. Vol. 21, No. 2, 138-142, 2006   과학기술학회마을
30 Lee, S.G., Dermal and Ocular Exposure During The Spray Application of Selected Industrial Chemicals, PhD Thesis, Descipline of Public Health, The University of Adelaide, South Australia, 2005
31 Liu Y., Stowe M., Walsh F., Cullen M., Sparer J., Holm C. and Redlich C., Biological monitoring to assess exposure to hexamethylene diisocyanate in auto body repair shops., Yale University School of Medicine, New Haven, CT; M. Berode, University of Lausanne, Lausanne, Switzerland; M. Boeniger, NIOSH, Cincinnati, OH. Am. Ind. Hyg. Assoc., URL: www.aiha.org/abs01/01biom.html, 2001
32 Berode M., Testa B. and Savolainen H., Bicarbonate- catalyzed hydrolysis of hexamethylene diisocyanate to 1,6-diaminohexane, Toxicol. Lett., Vol. 56, 173-178, 1991   DOI   ScienceOn
33 Meredith S.K., Taylor V.M. and McDonald J.C., Occupational respiratory disease in the United Kingdom 1989; A report to the British Thoracic Society and the Society of Occupational Medicine by the SWORD project group, Br. J. Ind. Med., Vol. 48, No. 292, 1991
34 Williams N.R., Jones K. and Cocker J., Biological monitoring to assess exposure from use of isocyanates in motor vehicle repair, Occup. Environ. Med., Vol. 56, No. 9, 598-601, 1999   DOI   ScienceOn
35 Hardy H.L. and Devine J.M., Use of organic isocyanates in industry-Some industrial hygiene aspects, Ann. Occup. Hyg., Vol. 22, 421-427, 1979   DOI   ScienceOn
36 McDonald, JC, Chen, Y, Zekveld, C and Cherry, NM. Incidence by occupation and industry of acute work related respiratory diseases in the UK, 1992-2001. Occup Environ Med, Vol. 62, 836-842, 2005   DOI   ScienceOn
37 Ucgun I., Ozdemir N., Metintas M., Meintas S., Erginel S. and Kolsuz M., Prevalence of occupational asthma among automobile and furniture painters in the center of eskisehir(Turkey): The effects of atopsy and smoking habits on occupational asthma, Allergy, Vol. 53, No. 11, 1096-1100, 1998   DOI   ScienceOn
38 SABRE, Surveillance of Australian Workplace Based Respiratory Events, Monash University, ABN 12 377 614 012, Updated Oct 7, 2005
39 Pisaniello D. and Muriale L., An analysis of respiratory syndrome among car painters exposed to isocyanates, J. Occup. Health Safety: Australia and New Zealand, Vol. 5, No. 4, 335-341, 1989b