• Title/Summary/Keyword: Producing Organization

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Purification of Therapeutic Serums of Snake Anti-Venom with Caprylic Acid

  • Norouznejad, Nilofar;Zolfagharian, Hossein;Babaie, Mahdi;Ghobeh, Maryam
    • Journal of Pharmacopuncture
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    • v.25 no.2
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    • pp.114-120
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    • 2022
  • Objectives: Antivenom serums have been used extensively for over a century and are the only effective treatment option for snake bites and other dangerous animal envenomations. In therapeutic serum centers, a wide range of antivenoms is made from animal serum, mainly equine and sheep, that are immunized with single or multiple venoms. This work aimed to use caprylic acid (CA) to purify therapeutic snake antivenom. Methods: Plasma was obtained from equine immunized with a mixture of venoms. Immunized plasma was obtained by precipitation of different concentrations (2-5%) of CA. This methodology was compared to that based on ammonium sulfate (AS) precipitation. Sediment plasma proteins were purified by ion-exchange chromatography. Protein assay, SDSPAGE, and agar gel diffusion were performed. Results: The total protein precipitation with AS was higher than precipitation with CA, but the best results were obtained when CA was added to the plasma until a final CA concentration of 5% was reached. Chromatography and electrophoresis indicated a stronger band for the 5% CA, and the gel diffusion assay showed antigen-antibody interaction in the purified serum. Conclusion: The use of CA compared to the routine method for purifying hyperimmune serums is a practical and cost-effective method for preparing and producing therapeutic serums. It constitutes a potentially valuable technology for alleviating the critical shortage of antivenom in Iran.

Typological characteristic of the comics published gutter (출판만화 칸새의 유형별 특징)

  • Lee, Suk Jae;Yoon, Ki Heon
    • Cartoon and Animation Studies
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    • s.33
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    • pp.271-291
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    • 2013
  • Cartoons exhibit contents and images and deliver them to readers by repeating frames. Frames embody the cross sectional factors of space-time, and the repetition of frames makes those cross sectional factors into a continuous flow. The gutter, which exists between frames, takes the role to make the continuous flow link smoothly, and at the beginning stage of the gutter, the operating of the gutter was usually passive by the frame meanings. However, the gutter is not just a medium for linking the frames, but is an efficient participation device for creating new expression methods of cartoon organization. By producing new directing methods for cartoon organization, the distinctive functions of the gutter have been kept alive with cartoon history. The distinctive functions of the gutter can be divided largely into transition function, reminiscence function, speech balloon function, pen function, and decorative function. And those functions perform actively as direct expression method of the gutter. When those functional methods are expressed by the author's intention and the frequency of them is generalized according to described contents, using each author's individual differences can suggest direction for new directing organization of cartoons.

A Study on the Quality Perceptions of Red Pepper Growers (고추 재배 농가들의 품질 인식에 관한 연구)

  • Kim, Jeong-Seop;Hwang, Jeong-Im
    • Journal of Agricultural Extension & Community Development
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    • v.12 no.2
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    • pp.173-185
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    • 2005
  • This article indicates that the perceptions on the quality of agro-food are socially constructed. Farmers who were producing red pepper in Eumsung county had somewhat different perceptions on the quality of red pepper according to their own marketing channels. Farmers who were selling their red pepper to consumers by direct marketing tend to think the quality attributes more important as follows; information on producers, ingredients, taste and smell, amount of pesticides input, cleaning the harvested red pepper, quality certification by public authority, and brands. Consumers tend to think safety and production area more important, while farmers tend to think the quality attributes as follows; taste, color, variety, soil environment, and largeness. Based on these research findings, we can give some recommendations as follows; 1) the agricultural extension organization in the Eumsung county should change the strategy for local agriculture towards quality management of red peppers. and 2) the local government need to examine the feasibility of quality certifying on red pepper.

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Effects of Ionizing Radiation on Plants and the Radiological Protection of the Environment

  • Stanislav A. Geras'kin;Kim, Jin-Kyu
    • Korean Journal of Environmental Biology
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    • v.21 no.4
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    • pp.321-327
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    • 2003
  • Differences between the principles for the radiological protection of man and the environment are compared. The derived levels of exposure for man and biota recommended by the international agencies with dose rates for chronic radiation producing effects at different levels of biological organization were given in terms of the biological effects. Cytogenetic effects on plants after an exposure to ionizing radiation at low doses alone and in combination with other factors are discussed. A wide range of experimental data were analysed and the general conclusions were extracted to cover the topics such as non-linearity of dose response, synergistic and antagonistic effects of the combined exposure of different factors, radiation-induced genomic instability, and the phenomena of radioadaptation.

Trends in US Nursing Research: Links to Global Healthcare Issues

  • Kenner, Carole A.
    • Journal of Korean Academy of Nursing Administration
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    • v.23 no.1
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    • pp.1-7
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    • 2017
  • Nursing research in the United States (US) spans several decades. Many of the priorities/trends have stayed through the years. Today, the goal of producing evidence to support nursing care interventions coupled with the drive for Magnet Recognition has encouraged academic nurses (faculty) to work with nurse clinicians to form research teams. Interdisciplinary research teams have also formed to address growing concerns over patient safety and quality care. These issues are not just US issues but global ones. This article addresses US trends with the link to global research trends. The role that organizations such as the International Council of Nurses (ICN), the World Health Organization (WHO), and the Council of International Neonatal Nurses, Inc. (COINN) pay in shaping research agendas and promoting nursing research is highlighted. It emphasizes the key role that nurses, especially nurse leaders/administrators play in changing health outcomes through support of nursing research.

A Historical Study on the Paisley Shawl Design -Focus on Kashmir Shawl- (페이즐리 숄 디자인에 관한 역사적 고찰 -카슈미르 숄을 중심으로-)

  • Kim Hee-Sun
    • Journal of the Korea Fashion and Costume Design Association
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    • v.7 no.3
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    • pp.39-52
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    • 2005
  • This paper is to study about paisley shawl and paisley motif to focus on Kashmir shawl. Kashmir shawl and paisley shawl of Europe can be identified by the use of 'pine cone' motif. Early 19th Europe textile manufactures began imitating the Kashmir shawl, the motif began to be called 'paisley', after Paisley, Scotland, one of the largest producers of imitation Karshmir shawls. This study is to analyze on origin of shawl and paisley motif at the theoretical background. And main issues are to study on organization of the Kashmir shawl indusry, weaving technic and producing process, development of motif, change of size and border design of shawl, difference of Woven Kashmir shawl, Patchwork shawl and hml shawl, causes of decline to shawl industry, differences of between Kashmir and European shawl etc. The result of this study can help to understand correct and accurate information, knowledge of paisley motif and paisley shawl.

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Development of Indicators for Evaluating the Size of Economic Investment for Child Care in Korea (한국아동보육사업의 경제적 규모 평가를 위한 지표개발 연구)

  • Lee, Seung-Hee;Paik, Il-Woo;Kim, Myoung-Soon
    • Korean Journal of Child Studies
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    • v.26 no.1
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    • pp.183-202
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    • 2005
  • This study performed intensive indicators based on a model of economics of education. Trends of childcare in Korea were obtained by producing values developed with statistical data. Results showed that such simple initial indicator values as numbers of children, institutions and teachers have improved. However, intensive indicator values that take demographic and economic conditions into consideration have not reached the same rate of progress as the initial indicator values. In other words, qualitative growth remains at an unsatisfactory level in comparison to quantitative growth and to qualitative growth in members of the Organization for Economics Cooperation and Development (OECD).Thus, financial investment by the government should be expanded in order to reach the desired level of high quality in daycare for children.

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Recent Progresses in the Linguistic Modeling of Biological Sequences Based on Formal Language Theory

  • Park, Hyun-Seok;Galbadrakh, Bulgan;Kim, Young-Mi
    • Genomics & Informatics
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    • v.9 no.1
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    • pp.5-11
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    • 2011
  • Treating genomes just as languages raises the possibility of producing concise generalizations about information in biological sequences. Grammars used in this way would constitute a model of underlying biological processes or structures, and that grammars may, in fact, serve as an appropriate tool for theory formation. The increasing number of biological sequences that have been yielded further highlights a growing need for developing grammatical systems in bioinformatics. The intent of this review is therefore to list some bibliographic references regarding the recent progresses in the field of grammatical modeling of biological sequences. This review will also contain some sections to briefly introduce basic knowledge about formal language theory, such as the Chomsky hierarchy, for non-experts in computational linguistics, and to provide some helpful pointers to start a deeper investigation into this field.

Charaterization of an Escherichia coli O157:H7 Strain Producing Verotoxin 2Isolated from a Patient in Korea

  • Park, Wan;Sohn, Chang-Kyu;Wan Huh;Kim, Byung-Chun
    • Journal of Microbiology
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    • v.38 no.2
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    • pp.93-98
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    • 2000
  • Nine hundred patients diagnosed with diarrhea or hemorrhagic uremic syndrome in the Kyungpook Province, Korea, were examined from November 1998 to February 2000. One patient in Kumi appeared to possess the Escherichia coli O157:H7 strain, which is very important in clinical decision making and public health action. The isolated strain, an E. coli O157:H7 KM, contained a 60 MDa plasmid and typical virulence genes including the verotoxin 2 gene, ehxA gene (encoding enterohemorrhagic hemolysin), and eae (encoding attaching and effacing protein-intimin) gene. This strain produced only verotoxin 2. Pulsed field gel electrophoretic analysis showed that the genomic organization of the E. coli O157:H7 KM strain may differ greatly from those of representative strains previously reported in the United States and Japan.

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A Studyon Relationship among the Key Dimensions of Quality Management (품질경영 핵심영역간의 상관관계연구)

  • 최현경;박재홍
    • Journal of Korean Society for Quality Management
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    • v.26 no.1
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    • pp.11-26
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    • 1998
  • A key aspect of theoretical and practical development of quality management is articulation of the distinction between quality management practices(input) and quality performance (output), which to date has been blurred under the broad heading of 'quality'. Recent literature primarily addressed measurement of quality performance but very little empirical research focuses specifically on quality management practices. In order to understand quality cause and effect, it is necessary to specify and measure quality management practices (cause) as well as quality performance (effect). This paper identifies and substantiates the key areas of quality management that must be implemented to achieve effective quality management, then analyzes relationships among those areas. In doing so, it establishes the basis for subsequent research by producing a profile of organization-wide quality manage-ment and provides the direction and priority of quality management practices for practitioners.

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