• KSBB Journal
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• v.21 no.2
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• pp.96-102
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• 2006

Recently, it has been known that Hericium erinaceum is a one of the very useful functional materials with great attention in mushroom processing industry. In present study, a liquid culture which was not studied systematically until now, was conducted as a method of cultivation for H. erinaceum, and also examined the characteristics of the liquid culture and conditions of process optimization. A good basal medium was selected through the cultivation of 16 species mushroom media and the optimum condition for medium and cultivation were chosen by response surface method. From these results, the optimum condition of medium for mushroom was 3% glucose, 0.2% yeast extract/peptone(1:1) and 0.1% $KH_2PO_4/MgSO_4$(1:1) and also the optimal culture condition was obtained at inoculum of 13.42%, temperature of $22.3^{\circ}C$ and pH of 5.7. The mycelial dry weight of 9 g/I was obtained under these conditions and this amount was about 1.7 times higher than that which were cultivated in basal medium for 8 days.

• KSBB Journal
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• v.20 no.1 s.90
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• pp.60-65
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• 2005

The objective of this work was to evaluate a solid-state fermentation process for the practical production of arachidonic acid(AA) by Mortierella alpina ATCC 32222. In the present investigation, batch culture kinetics for both submerged- and solid-state fermentations was carried out at $25^{\circ}C$ to identify the relationship between growth and arachidonic acid (AA) production. Glucose and yeast extract were used in submerged fermentations by using flasks, while rice bran was used as a sole raw material in the other type of fermentations by using a series of Petri dishes. It was evident that a mixed-growth associated pattern existed between the two variables, irrespective of modes of fermentations. The effect of carbon to nitrogen (CfN) ratio on AA production in solid-state fermentation was studied in the range of 6.5 - 20. As a result, an optimum condition was found to be 6.5. Supplementary carbon source was not necessary to meet the optimum C/N ratio. Unlike the Previous results obtained by other researchers, a supplement of sodium glutamate up to $4\%$ (w/w) to the rice bran medium did not have a positive effect on the AA productivity. However, an increase in AA productivity was obtained with the rice bran medium supplemented with sesame oil.

• Journal of the Korea Institute of Building Construction
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• v.15 no.3
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• pp.265-271
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• 2015

This study is intended to produce a PC (Precast Concrete) member without a steam curing process in developing the high early strength concrete satisfying the condition of 10MPa in compressive strength at the age of 6 hours, and is intended to ensure economic feasibility by increasing the turnover rate of concrete form. Hence, high early strength cement with high $C_3S$ content and the hardening accelerator of powder type accelerating the hydration of $C_3S$ was used. And the properties of concrete were evaluated according to the hardening accelerator mixing ratio (0, 1.2, 1.6, 2.0). No big difference was found from the tests of both slump and air content. When 1.6 % or higher amounts of the hardening accelerator were mixed, the compressive strength of 10MPa was achieved at the age of 6 hours. From the test results of autogenous (drying) shrinkage and plastic shrinkage, it can be seen that there was a difference according to hydration reaction rate due to the addition of the hardening accelerator. However, it was shown that no problem arose with crack and durability. And it was shown that resistance to freezing-thawing, carbonation, and penetration were excellent.

• Tuberculosis and Respiratory Diseases
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• v.69 no.2
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• pp.81-94
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• 2010

Background: Autophagy is an important adaptive mechanism in normal development and in response to changing environmental stimuli in cancer. Previous papers have reported that different types of cancer underwent autophagy to obtain amino acids as energy source of dying cells in nutrient-deprived conditions. However, whether or not autophagy in the process of lung cancer causes death or survival is controversial. Therefore in this study, we investigated whether nutrient deprivation induces autophagy in human H460 lung cancer cells. Methods: H460, lung cancer cells were incubated in RPMI 1640 medium, and the starved media, which are BME and RPMI media without serum, including 2-deoxyl-D-glucose according to time dependence. To evaluate the viability and find out the mechanism of cell death under nutrient-deprived conditions, the MTT assay and flow cytometry were done and analyzed the apoptotic and autophagic related proteins. It is also measured the development of acidic vascular organelles by acridine orange. Results: The nutrient-deprived cancer cell is relatively sensitive to cell death rather than normal nutrition. Massive cytoplasmic vacuolization was seen under nutrient-deprived conditions. Autophagic vacuoles were visible at approximately 12 h and as time ran out, vacuoles became larger and denser with the increasing number of vacuoles. In addition, the proportion of acridine orange stain-positive cells increased according to time dependence. Localization of GFP-LC3 in cytoplasm and expression of LC-3II and Beclin 1 were increased according to time dependence on nutrient-deprived cells. Conclusion: Nutrient deprivation induces cell death through autophagy in H460 lung cancer cells.

• Journal of the Korean BIBLIA Society for library and Information Science
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• v.14 no.1
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• pp.199-218
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• 2003

The discriminating power of journal evaluation criteria of Korean medical journals were measured. The study used the data of 76 medical journals, collected in the "Korean Medical Journal Evaluation" process conducted by the Korean Association of Medical Journal Editors (KAMJE) between 1997 and 1999. For each evaluation criterion, the distribution of the individual score vs the total score of a journal received was plotted and their correlations were analyzed. It is found that the evaluation criteria with a high discriminating power are the ones associated with the peer review system and the journal editing. The evaluation criteria with a low discriminating power are the journal frequency and how often a chief editor is changed. Some evaluation criteria such as "Journal holding rates of medical libraries" and "year-end index" need modifications in the evaluation methods. Other evaluation criteria such as "Journal self-citation rate","SCI citation rate" and "SCI impact factor" need to modify the score ranges. It is recommended that the new evaluation criteria such as "citation rate by Korean medical journals" and "Access availability of the journal information through major Korean medical abstract databases" should be added.formation through major Korean medical abstract databases" should be added.dded.

• Journal of the Korean BIBLIA Society for library and Information Science
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• v.26 no.3
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• pp.129-150
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• 2015

As the digital technologies and internet have advanced, data have centered in the process of meaningful scientific ramifications and policy making in a wide variety of fields. Data curator in charge of managing data plays a significant role in terms of improving the effectiveness and efficiency of data management and re-uses. The purpose of this study is to identify the core competencies for data curator. For achieving the purpose of this study, two sets of data were collected. First, a total of 255 job descriptions were collected from the web sites including ARL, Digital Curation Exchange, Code4lib, ASIS&T JobLine for the period of 2011-2014. Second, in-depth interviews with five data curators from four diverse organizations were collected. The two sets of data were analyzed into seven categories identified from the related studies. Findings of this study showed that core competencies for data curator were identified into four categories, communication skills, data management techniques, knowledge and strategies for data management, and instructions and service provisions for users. The implications of this study can be considered as integrated and professional curriculum developments for data curator with core competencies.

• Journal of the Korean BIBLIA Society for library and Information Science
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• v.28 no.4
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• pp.5-33
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• 2017

In this study, an investigation has been made on the status of the issuance of librarian qualification, the status of operating Subject specialized librarians at home and abroad, the status of professional manpower of the similar cultural facilities, and their recruitment method, based on which an attempt has been made to propose a way to nurture the Subject specialized librarians. First, I propose a method for training Subject specialized librarians through a regular curriculum and a retraining process, while suggest the ways to nurture the Subject specialized librarians from undergraduate and also nurture the existing librarians to become the Subject specialized librarians. Second, the basic qualification of the Subject specialized librarians must have a career of more than 3 years in a specific subject area with a master's degree or higher, and in order to have a subject area background, it is proposed that a bachelor's degree or a master's degree must absolutely be acquired in the corresponding subject area. Third, in order to improve the treatment of such Subject specialized librarians, the Subject specialized librarians in the administrative service group could be organized into a research librarian (or library and information science) series and types as a subordinate literary series under the researcher position. That is, it is proposed to differentiate the librarians and the Subject specialized librarians by reorganizing series and types of the Subject specialized librarians while maintaining the current librarian series.

• Journal of the Korean BIBLIA Society for library and Information Science
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• v.31 no.1
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• pp.67-87
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• 2020

The purpose of this study is to analyze current status and teacher librarians' perceptions of school library space composition and indoor environment, and propose some methods for the school library to be a basic educational facility. The space most secured by the 126 teacher librarians who participated in the survey was the free reading area, and the space with the lowest level was the media production and group project area. The most important types of spaces for teacher librarians are the teaching area and the free reading area, while the recognition of the importance of media production and group project areas is relatively low. Among the elements of indoor environmental assessment, they showed that safety and comfort were the most important but diversity and flexibility were relatively less important. The result of this analysis is different from the school and library policy direction that emphasizes the learning commons and maker spaces. Teacher librarians still seem to appreciate the importance of traditional library space. Therefore, it is necessary to include the establishment and operation of maker spaces and learning commons in the teacher librarians training and retraining process. In addition, it is necessary to increase the participation of users such as teachers, students, and parents in space composition and interior design initiatives to increase the user's interior environment satisfaction.

• Journal of the Korea Computer Graphics Society
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• v.9 no.3
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• pp.23-29
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• 2003

There is the temporal correlation of the video sequence between the motion vector of current block and the motion vector of the previous block. If we can obtain useful and enough information from the motion vector of the same coordinate block of the previous frame, the total number of search points used to find the motion vector of the current block may be reduced significantly. In this paper, we propose the block-matching motion estimation using an adaptive initial search point by the predicted motion information from the same block of the previous frame. And the first search point of the proposed algorithm is moved an initial point on the location of being possibility and the searching process after moving the first search point is processed according to the fast search pattern. Simulation results show that PSNR(Peak-to-Signal Noise Ratio) values are improved UP to the 1.05dB as depend on the image sequences and improved about 0.33~0.37dB on an average. Search times are reduced about 29~97% than the other fast search algorithms. Simulation results also show that the performance of the proposed scheme gives better subjective picture quality than the other fast search algorithms and is closer to that of the FS(Full Search) algorithm.

• Research in Community and Public Health Nursing
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• v.11 no.2
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• pp.358-372
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• 2000

The purpose of this study was to describe the way of life (such as smoking habits, alcohol consumption, exercise, duration of sleep, eating habits etc.), physical. psychological and overall health complaints and to identify the relationship between the way of life and health complaints of the nursing students. Data was collected with the self-administered OMI( Okayama Medical Index Health Questionnaire, devised Cornell Medical Index) from 766 nursing students and was analyzed. For data analysis, descriptive statistics and an ANOVA with an SPSS/PC+ program were used. The results were as follows: 1. The mean age of subjects was 21.0557(2.7618) years old in their 1st, 2nd, 3rd and 4th year-classes of nursing departments and college students in 4 regions of Korea. 62.1% of subjects were of the proper body weight, 2.0% were overweight, and 28.3% were underweight. Most subjects did not have a past history of disease, but 1.8% of subjects had experienced a blood transfusion. 2. 28.3% of the subjects had averaged 7 hours of sleep, 98.5% were nonsmokers, 91.2% were nondrinkers, 74.7% of subjects had milk intake sometimes, 53.7% of the subjects had an average salt intake, 49.6% of the subjects usually had a green vegetable intake, 45.4% of the subjects sometimes had fatty food intake, 64.8% of the subjects had good taste, 29.5% of the subjects enjoyed physical exercise. 3. The highest percentages of 'yes' among physical. psychological and overall health complaints were observed in the question 'Do you have gastric pain?'(60.2%), 'Are you confused of disorderly?' (37.2%), 'Physical body was burdensome and fatigued.'(57.3%). 4. The total O.M.I. score ranged from 1 to 89 with an average of 22.91(SD=12.10). A statistically significant difference was observed for the physical. psychological complaints for alcohol consumption. and for the psychological complaints for salt and fatty food intake. These conclusions should provide grounds for future studies of strategies for health promoting lifestyle for nursing students and their health concerns. Further research is required to investigate the life environmental and psychological factors affecting the way of life for nursing students and their health status, to analyze the health behavior of nursing students related with their culture and consciousness. Also epidemiologic research methodology, such as prospective cohort study should be considered to explore the performing process of nursing student's health behavior related with the occurrence of diseases.