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Effects of Dietary $\omega3$ and $\omega6$ Fatty Acids on the Fatty Acid Composition of RBC and Brain Synaptosomal, Microsomal and mitochondrial Phospholipids and on Behavioral Development of Rats (식이 $\omega3$$\omega6$계 지방산 조성이 제 2세대 쥐의 RBC과 뇌조직 Synaptosome, Microsome 및 Mitochondria의 인지질 및 행동발달에 미치는 영향)

  • 엄영숙
    • Journal of Nutrition and Health
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    • v.29 no.8
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    • pp.849-860
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    • 1996
  • The supply of different fatty acids during the development period has significant effects. This study examined the effects of dietary $\omega$3 and $\omega$6 fatty acid compositions on phospholipids (PLs) of RBC and rat brain subcellular fractions (synaptosome, microsome, mitochondria), and on learning ability of the 2nd generation rat. Rats were fed experimental diets 3-4 wks prior to the conception. Early in the lactation period, the feeding mothers were exchanged. Diets consisted of 10% fat(by weight), which was either safflower oil('S') poor in $\omega$3 fatty acids or computer-searched mixed oil('M') with P/M/S ratio, 1/1.4/1 and $\omega$6/$\omega$3 ratio, 6.1/1. The 'S' and 'M' rats were subdivided further into SS, SM, MS & MM rats according to their lactation stauts. At 3 (weaning) & 9 wks of age, the percentage of total $\omega$3 fatty acids to their lactation status. At 3 (weaning) & 9 wks of age, the percentage of total $\omega$3 fatty acids and the ratios of $\omega$3/$\omega$6 fatty acids in PLs of RBC and brain subcellular fractions in SM and MM groups fed milk from the mixed oil-fed mothers for 2 wks tended to be higher than those in SS and MS groups respectively. In contrast, the concentrations of $\omega$6 fatty acids, especially 22:5$\omega$6 in all fractions, were significantly lower in the SM & MM groups compared to those of the SS & MS groups respectively. In contrast, the concentration of $\omega$6 fatty acids, especially 22:5$\omega$6 in all fractions, were significantly lower in the SM & MM groups compared to those of the SS & MS groups, The values for the DHA$\omega$3/22:5$\omega$6 ratios after the lactation period were markedly higher in the groups (SM & MM) which were reared by mixed oil(MO) fed mothers. In carring out Y-water maze at 9th wk of age, the SM(4.2$\pm$0.5) & MM (5.3$\pm$0.5) groups made significantly less errors compared to the SS(6.2$\pm$0.6, p<0.05 compared with SM) & MM (7.2$\pm$0.5, p<0.05 compared with MM) groups which were lactated by the safflower oilfed mothers. Therefore, by feeding a balanced fatty acid diet from the lactation period up to 9 wks of age as compared with the groups fed $\omega$3 fatty acid-deficient diet regardless of mother's diet given before parturition. The levels of DHA(synaptosome) and 22:5$\omega$3 (mitochondria) were positively correlated not only with these values in RBC but also with visual discriminating ability. The levels of DHA and 22:5$\omega$3 in RBC can, therfore, reflect visual discriminatng ability in the rat.

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The Generating Processes of Scientific Emotion in the Generation of Biological Hypotheses (생물학 가설의 생성에서 나타난 과학적 감성의 생성 과정)

  • Kwon, Yong-Ju;Shin, Dong-Hoon;Park, Ji-Young
    • Journal of The Korean Association For Science Education
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    • v.25 no.4
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    • pp.503-513
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    • 2005
  • The purpose of this study was to analyze the generating processes of scientific emotion, that appears during the generation of biological hypotheses. To perform the study, a tentative model was set up through pilot test, a think-aloud training procedure was planned and a standardized interview instrument was developed before getting protocols. In this study, 8 college students were selected to bring out protocol through the method of think-aloud, retrospective debriefing, focused interview and observing. As the result of analysis of the collected protocol through coding scheme, 4 types of process for scientific emotion-generating were sorted out. First type was a basic process which was a feeling process in prior to recognition. Second type was a retrospective process that explains the process of retrospect for emotional memory based on the past. Third type was a cognitive process and it explains emotion that occurs during thinking process to achieve cognitive goal. Fourth type was an attribution process and it explains that emotion is generated in the process of attribution for cognitive goal's achievement. These types of process of scientific emotion-generating can contribute the basis for developing cognitive model of EBL (Emotional Brain-based Learning) strategy.

The Effects of Science Lessons Applying STEAM Education Program on the Creativity and Interest Levels of Elementary Students (STEAM 프로그램을 적용한 과학수업이 초등학생의 창의성과 과학교과 흥미도에 미치는 영향)

  • Kim, Deok-Ho;Ko, Dong Gook;Han, Myeong-Jae;Hong, Seung-Ho
    • Journal of The Korean Association For Science Education
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    • v.34 no.1
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    • pp.43-54
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    • 2014
  • According to trends in scientific technical competition, many countries around the world are interested in and focused on the STEAM integrated education. By observing the fact that the goal of our country's science education is to cultivate creative workers who have scientific knowledge, the need for STEAM integrated education cannot be denied. Therefore, the purpose of this study was to develop the STEAM integrated program focused on themes that considered activities and interest in the grade 6 science subject in order to identify its influence on the creativity and interest levels of elementary students. The STEAM integrated education program in this study was developed so that it can be applied as a unit review or reinforcement activities in the closing activities per unit in grade 6. The focus was placed on heightening students' creativity and interest in science subject learning through a program focused on activities per theme. As a result of applying the developed STEAM integrated program in prior and post conditions on 3 elementary school's students in J Province, it was discovered that significant improvement was found in the creativity and scientific interest of elementary students in the experimental group, compared to the control group. Therefore, continuous and systematic development of the STEAM integrated education program is required, and moreover, it must be developed for all elementary grade levels and efforts should be put into actively applying the program in the field of education.

A Study on the Development of Instruction Model on Project inquiry and Materials for the New Subject of 'Mathematical Task Inquiry' in the curriculum revised in 2015 (2015 개정 <수학과제 탐구> 신설 과목 운영을 위한 과제 탐구의 수업 모형 및 자료 개발 연구)

  • Hwang, Hye Jeang;Kim, Ju Mi
    • Communications of Mathematical Education
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    • v.32 no.3
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    • pp.363-383
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    • 2018
  • The subject of 'Mathematical Task Inquiry' was introduced newly in the curriculum revised in 2015. The subject is dealt with after completing the subject of 'mathematics' to be dealt with in the tenth grade. Its main content is comprised of the understanding and learning of the purpose and procedure of inquiry task and of study ethics, and its educational goal is to enforce the prior mathematical knowledge and to obtain the ability to select interesting topics that combine mathematics with other subjects. However the textbook of the subject does not exist, and teachers should handle with the subject with responsibility for their own ways. Because of this reason, this study is to develop an instruction model on project(task) inquiry model and materials. Namely, according to the model, students is guided to select and decide the subject of the task, and develop the task for themselves, solve it with peers in cooperation, and announce the solution and their feelings. During those students' exploration and activities, the role of teachers is to guide students to complete their work. By the way, in order to develop more creative tasks that is appropriate to their academic and cognitive level, this study conducted the experimentation for the subject of 9 students (6 girls and 3 boys), who are scheduled to advance to the 11 grade of J high school located in G domestic. The experimentation was consisted of three class and after the third class, the semi-structured interview was conducted immediately for the students.

『Bonchojeonghwa(本草精華)』, Medical Historical Approach to Bibliographic Notes (『본초정화(本草精華)』의 해제(解題)에 관한 역사학적(醫史學的) 접근)

  • Kim, Hong-Kyoon
    • The Journal of Korean Medical History
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    • v.24 no.2
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    • pp.25-55
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    • 2011
  • The currently existing "Bonchojeonghwa (本草精華)" is a manuscript without the preface and the epilogue, composed of 2 books in 2 volumes. This book is a quintessence of knowledge on science of medicinal ingredients (medicinal phytology I herbal science) as well as an trial of new development in Chosun medical science. I.e. this book includes surprising change representing medical science in Chosun dynasty as a single publication on science of medicinal ingredients. It holds a value essential to clinician as a specialized book in medicinal ingredients, and Includes richer content on medicinal ingredients than any other books published before. In addition, it is away from boring list-up of superfluous knowledge as seen in "Bonchokangmok(本草綱目)" published in China, and well summarizes essential knowledge which can be used within a range of medicines available in Korea. This book has an outstanding structure that can be even used in today's textbook on science of medicinal ingredients, as it has clear theory, system and classification. Because it handles essential learning points prior to prescription to disease, it is possible to configure new prescription and adjustment of medicinal materials. Moreover, this book can play a good role for linguistic study at the time of publication, because it describes many drugs in Hangul in many parts of the book. "Bonchojeonghwa" includes a variety of animals, plants and mineral resources in Korea, like "Bonchokangmok" which was recently listed in UNESCO. As such, it has a significance in natural history as well as pharmacy in Korean Medicine. It has various academic relationships all in biologic & abiologic aspects. It has importance in sharing future biological resources, building up international potential, setting up the standard for biologic species under IMF system, and becoming a base for resource diplomacy. We should not only see it as a book on medicinal ingredients in terms of Oriental Medicine, but also make an prudent approach to it in terms of study strengthening Korea's national competitiveness. After bibliographical reviewing on the features & characteristics of the only existing copy of "Bonchojeonghwa" housed in Kyujanggak(奎章閣) of Seoul National University, the followings are noted. First, "Bonchojeonghwa" is a specialized book on medicinal ingredients voluntarily made by private hands to distribute knowledge on drugs in the desolate situation after Imjinoeran (Japanese Invasion in 1592), without waiting for governmental help. Second, it raised accessibility and practicality by new editing. Third, it classified 990 different kinds of drugs into plant, animal, and mineral at large, and dassified more in detail into 15 'Bu' and 48 'Ryu' at 258 pages. Fourth, the publication of this book is estimated to be around 1625~1633, at the time of Injo's reign in 17th century. Fifth, it contains the existing & up-to-date knowledge at the time of publication, and it is possible to see the supply-demand situation by Hangul descriptions in 149 places in the book. By the fact that there are many linguistic evidences of 17th century, explains well when the book was published.

A neural-based predictive model of the compressive strength of waste LCD glass concrete

  • Kao, Chih-Han;Wang, Chien-Chih;Wang, Her-Yung
    • Computers and Concrete
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    • v.19 no.5
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    • pp.457-465
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    • 2017
  • The Taiwanese liquid crystal display (LCD) industry has traditionally produced a huge amount of waste glass that is placed in landfills. Waste glass recycling can reduce the material costs of concrete and promote sustainable environmental protection activities. Concrete is always utilized as structural material; thus, the concrete compressive strength with a variety of mixtures must be studied using predictive models to achieve more precise results. To create an efficient waste LCD glass concrete (WLGC) design proportion, the related studies utilized a multivariable regression analysis to develop a compressive strength waste LCD glass concrete equation. The mix design proportion for waste LCD glass and the compressive strength relationship is complex and nonlinear. This results in a prediction weakness for the multivariable regression model during the initial growing phase of the compressive strength of waste LCD glass concrete. Thus, the R ratio for the predictive multivariable regression model is 0.96. Neural networks (NN) have a superior ability to handle nonlinear relationships between multiple variables by incorporating supervised learning. This study developed a multivariable prediction model for the determination of waste LCD glass concrete compressive strength by analyzing a series of laboratory test results and utilizing a neural network algorithm that was obtained in a related prior study. The current study also trained the prediction model for the compressive strength of waste LCD glass by calculating the effects of several types of factor combinations, such as the different number of input variables and the relevant filter for input variables. These types of factor combinations have been adjusted to enhance the predictive ability based on the training mechanism of the NN and the characteristics of waste LCD glass concrete. The selection priority of the input variable strategy is that evaluating relevance is better than adding dimensions for the NN prediction of the compressive strength of WLGC. The prediction ability of the model is examined using test results from the same data pool. The R ratio was determined to be approximately 0.996. Using the appropriate input variables from neural networks, the model validation results indicated that the model prediction attains greater accuracy than the multivariable regression model during the initial growing phase of compressive strength. Therefore, the neural-based predictive model for compressive strength promotes the application of waste LCD glass concrete.

Initiating Smokeless Tobacco Use across Reproductive Stages

  • Begum, Shahina;Schensul, Jean J.;Nair, Saritha;Donta, Balaiah
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.17
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    • pp.7547-7554
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    • 2015
  • Background: The use of smokeless tobacco (SLT) among women is increasing in India, especially among those with limited education and resources. Preventing the initiation of SLT among women is critical since it has known negative consequences for oral and reproductive health. Most research on tobacco initiation in India focuses on adolescents. This paper addresses the unrecognized issues of post marital initiation among women of reproductive age, highlighting the importance of reproductive stages in women's tobacco initiation. The objective is to examine the correlates of SLT initiation among low income women in Mumbai from pre-marriage through early marriage, first pregnancy and beyond, using case examples to illustrate initiation during each of these stages. Materials and Methods: In 2011-2012, cross-sectional community level survey data were collected from a representative sample of 409 daily SLT-using married women aged 18-40 years in a low income community in Mumbai. Information on socio-demographics, initiation by reproductive stage, types of tobacco use, childhood exposure to tobacco, learning to use, and initiation influences and reasons were collected through a researcher-administered survey. Univariate and bivariate analysis assessed factors influencing initiation of SLT use by reproductive stage. In addition 42 narratives of tobacco use were collected from a purposive sample of pregnant and non-pregnant married women addressing the same questions in detail. Narratives were transcribed, translated, and coded for key concepts including initiation of tobacco use. Results: Thirty-two percent of women initiated SLT use before marriage, 44% initiated after marriage but before pregnancy, 18.1% initiated during their first pregnancy and the remainder started after their first pregnancy. Mean age of marriage among women in this study was 16 years. Younger women (i.e. age at time of the interview of less than 30 years) were 0.47 [95% CI (0.32, 0.87)] percent less likely to initiate after marriage than women aged more than 30 years. Women who got married before 18 years of age were 2.34 [95% CI (1.40, 3.93)] times more likely to initiate after marriage than their counterparts. Childhood exposure was a predictor for initiating SLT use prior to marriage but not after. Women reporting tooth and gum pain were 1.85 times more likely to initiate after marriage than their counterparts. Husband and neighbours were the most significant influences on post-marital initiation. Narratives highlighted differences in processes of initiation pre and post marriage and during pregnancy. Conclusions: Most tobacco prevention interventions are directed to adolescents in school. This study suggests that especially for low literate or illiterate women, school based interventions are ineffective. To be effective strategies to prevent SLT initiation must reach women in urban areas at or immediately after marriage and during their first pregnancy. Messages must negate culturally rooted beliefs about the health benefits of SLT in order to prevent initiation and onset of daily use.

Analysis of Teaching and Learning Results in Mathematics using Reconstructed Textbook -Focusing on Vocational High School- (재구성 교재를 활용한 수학과 교수·학습 결과 분석 -특성화 고등학교를 중심으로-)

  • So, Jae Hong;Jeon, Young Ju
    • The Journal of the Korea Contents Association
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    • v.16 no.4
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    • pp.179-194
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    • 2016
  • The purpose of this study is to find out how the reconstructed textbook for vocational high school students influences on students' scholastic achievement and affective domain when it is used in the class of vocational high school. To tackle the study problems, the researcher chose two classes of the first grade in G commercial high school and gave lessons to each of the two classes; one class, as an experimental group, was taught with the reconstructed textbook and the other, as a comparative group, was taught with the original textbook. The following results are derived from the study. First, it turned out in the post academic achievement test result, there is no significant difference between the experimental group and the comparison group, by significant level; .05. However, the prior academic achievement test result shows that the average of the comparison group is 0.44 points higher than the average of the experimental group, while the post test result shows that the average of the experimental group is 1.96 points higher than the average of the comparison group. Second, it turned out by the post affective domain test result, there is no significant difference between the experimental group and the comparison group, by significant level; .05, and any significant difference did not occur in all five areas. However, the whole point of the affective domain and the points of each area of experimental group are higher than those of the comparison group, and the degree of improvement in experimental group is also greater than that of the comparison group. In conclusion, the effectiveness of utilizing a reconstructed textbook in vocational high school math class can be expected in the long term.

Students' Informal Knowledge of Division in Elementary School Mathematics (자연수의 나눗셈에 관한 초등학교 학생의 비형식적 지식)

  • Park, Hyoun-Mi;Kang, Wan
    • Journal of Elementary Mathematics Education in Korea
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    • v.10 no.2
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    • pp.221-242
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    • 2006
  • For teaching division more effectively, it is necessary to know students' informal knowledge before they learned formal knowledge about division. The purpose of this study is to research students' informal knowledge of division and to analyze meaningful suggestions to link formal knowledge of division in elementary school mathematics. According to this purpose, two research questions were set up as follows: (1) What is the students' informal knowledge before they learned formal knowledge about division in elementary school mathematics? (2) What is the difference of thinking strategies between students who have learned formal knowledge and students who have not learned formal knowledge? The conclusions are as follows: First, informal knowledge of division of natural numbers used by grade 1 and 2 varies from using concrete materials to formal operations. Second, students learning formal knowledge do not use so various strategies because of limited problem solving methods by formal knowledge. Third, acquisition of algorithm is not a prior condition for solving problems. Fourth, it is necessary that formal knowledge is connected to informal knowledge when teaching mathematics. Fifth, it is necessary to teach not only algorithms but also various strategies in the area of number and operation.

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Improvement of basic Academic Skills for Junior College Students : Based on a Case Study of D College (전문대학 기초학습능력 향상 방안: D 대학 사례를 중심으로)

  • Choi, Kil-Sung;Lee, Seung-Hee
    • The Journal of the Korea Contents Association
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    • v.11 no.4
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    • pp.468-476
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    • 2011
  • A lack of basic academic skills of junior college students has negatively impacted on the quality of vacational education and student dropout prevention, and yet it is true that there still are unclear alternatives or solutions to come up with that concern. As a way to find out the actual levels of basic academic skills of junior college students and educational efforts to improve these skills, the study investigated prior studies and benchmarked strengths and weaknesses of the related educational programs and supporting systems operated by ten junior colleges around the nation. Further, the study addressed emerging issues and challenges related to basic academic skills, based on the case study of D college. Major research methodologies included literature review, surveys for students and faculty members and focus-group interviews of faculty members in order to examine the states of students' basic academic skills in the area of language, in particular. Accordingly, the study proposed several suggestions with which educational practitioners could assist in supporting students to acquire improved basic academic skills(such as the development of a competence-based curriculum, implementation of reliable diagnosis tools and supporting educational systems for evaluating students' basic academic skills and upgrading of diverse teaching and learning resources and methods).