• Title/Summary/Keyword: Prince

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Astaxanthin induces migration in human skin keratinocytes via Rac1 activation and RhoA inhibition

  • Ritto, Dakanda;Tanasawet, Supita;Singkhorn, Sawana;Klaypradit, Wanwimol;Hutamekalin, Pilaiwanwadee;Tipmanee, Varomyalin;Sukketsiri, Wanida
    • Nutrition Research and Practice
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    • v.11 no.4
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    • pp.275-280
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    • 2017
  • BACKGROUND/OBJECTIVES: Re-epithelialization has an important role in skin wound healing. Astaxanthin (ASX), a carotenoid found in crustaceans including shrimp, crab, and salmon, has been widely used for skin protection. Therefore, we investigated the effects of ASX on proliferation and migration of human skin keratinocyte cells and explored the mechanism associated with that migration. MATERIAL/METHOD: HaCaT keratinocyte cells were exposed to $0.25-1{\mu}g/mL$ of ASX. Proliferation of keratinocytes was analyzed by using MTT assays and flow cytometry. Keratinocyte migration was determined by using a scratch wound-healing assay. A mechanism for regulation of migration was explored via immunocytochemistry and western blot analysis. RESULTS: Our results suggest that ASX produces no significant toxicity in human keratinocyte cells. Cell-cycle analysis on ASX-treated keratinocytes demonstrated a significant increase in keratinocyte cell proliferation at the S phase. In addition, ASX increased keratinocyte motility across the wound space in a time-dependent manner. The mechanism by which ASX increased keratinocyte migration was associated with induction of filopodia and formation of lamellipodia, as well as with increased Cdc42 and Rac1 activation and decreased RhoA activation. CONCLUSIONS: ASX stimulates the migration of keratinocytes through Cdc42, Rac1 activation and RhoA inhibition. ASX has a positive role in the re-epithelialization of wounds. Our results may encourage further in vivo and clinical study into the development of ASX as a potential agent for wound repair.

Reexamination on Materials related to Wolji Palace - East Palace is not the Crown Prince's Palace (월지궁(月池宮) 관련 자료 재검토 - 동궁(東宮)은 태자궁(太子宮)이 아니다 -)

  • Choi, Young Sung
    • (The)Study of the Eastern Classic
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    • no.55
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    • pp.173-192
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    • 2014
  • Through excavation on Anapji Pond from March 1975 to December 1976, it was discovered that the whole area around Anapji Pond had been called East Palace (東宮) since 7th century and that the original name of East Palace was Wolji Palace (月池宮) through excavation in 1980. The excavation proved that the original name of Anapji Pond was 'Wolji.' In academic world, there are many scholars who recognize this place as the Crown Prince's palace for being called East Palace. East Palace (which is read Dong Palace with pronunciation in Korean alphabet) actually is another name for Crown Prince's palace. This place, however, cannot have served as Crown Prince's palace as 'independent, exclusive space.' After 7th century, there were detached palaces in Silla including East Palace South Palace North Palace and Yang Palace other than Jeong Palace in Wolseong. East Palace is a palace located in the east. The palace's name is based on bearing and it does not indicate Crown Prince's palace. This article proves that East Palace cannot have been Crown Prince's palace through newly analyzing materials related to Wolji Palace.

Optical diagnosis by near-focus versus normal-focus narrow band imaging colonoscopy in colorectal polyps based on combined NICE and WASP classification: a randomized controlled trial

  • Nisa Netinatsunton;Natcha Cheewasereechon;Tanawat Pattarapuntakul;Jaksin Sottisuporn;Kanet Kanjanapradit;Bancha Ovartlarnporn
    • Clinical Endoscopy
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    • v.55 no.5
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    • pp.645-654
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    • 2022
  • Background/Aims: Narrow Band Imaging (NBI) International Colorectal Endoscopic (NICE) and Workgroup Serrated Polyps and Polyposis (WASP) classifications were developed for optical diagnosis of neoplastic and sessile serrated polyps, respectively. Near-focus NBI with NICE combined with WASP criteria for optical diagnosis of colonic polyps has not yet been evaluated. We aimed to compare the accuracy of near-focus NBI (group A) with normal-focus NBI (group B) in real-time optical diagnosis of colorectal polyps using combined NICE and WASP criteria. Methods: Among 362 patients, 118 with 227 polyps were recruited. Groups A and B included 62 patients with 130 polyps (three lost polyps) and 56 patients with 106 polyps (six lost polyps), respectively. Optical diagnoses were compared with pathological reports. Results: The accuracy of optical diagnosis of neoplastic polyps in groups A and B was not significantly different (76% vs. 71%, p=0.52). WASP criteria provided all false positive diagnoses of sessile polyps as serrated polyps in 31 (16.2%) patients. Conclusions: Near-focus NBI was not superior to normal-focus NBI in optical diagnostics of neoplastic polyps using NICE criteria. In our study, WASP classification yielded all false positives in the diagnosis of sessile serrated adenomas/polyps. Routine real-life optical diagnosis of polyps is still unadvisable.

Cosmetic Outcomes and Quality of Life in Thai Women Post Breast Conserving Therapy for Breast Cancer

  • Thanarpan, Peerawong;Somrit, Mahattanobon;Rungarun, Jiratrachu;Paytai, Rordlamool;Duangjai, Sangtawan;Chanon, Kongkamol;Puttisak, Puttawibul
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.11
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    • pp.4685-4690
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    • 2015
  • Purpose: To evaluate the correlation between cosmetic outcome (CO), body image, and quality of life in post breast-conserving therapy (BCT) women. Materials and Methods: This cross-sectional study concerned one-year post-completed BCT Thai women. The data included subjective and objective CO with a questionnaire covering demographic and clinical data, anti-hormonal treatment status, Eastern Cooperative Oncology Group (ECOG) performance status, Self-Reported Cosmetic Outcomes (SRCO), Self-Reported Breast Symmetry (SRBS), Body Image Scale (BIS), and the Functional Assessment of Cancer Therapy with Breast Cancer subscale (FACT-B). Participants had breast photographs taken for the evaluation of objective cosmetic outcome (OCO) after breast cancer conservation treatment. The relationship between CO and FACT-B was tested using Spearman's rank correlation Results: A total 127 participants volunteered for the study. The participant characteristics were age 52(${\pm}9$), Buddhist 87%, married 65%, body mass index 25.0(${\pm}4.6$), breast cup size A-C 91%, college educated 60%, employed 66%, ECOG 0-1 95%, tumor size less than or equal to 2 cm 55%, no lymph node metastasis 98%, and taking tamoxifen 57%. Two percent of the participants regretted their decision to undergo BCT. The SRCO was excellent in 2%, good in 68%, fair in 30%, and poor in 0%. For SRBS, rates were 17%, 58%, 24% and 1% for excellent, good, fair and poor cosmetic outcomes, respectively. The BCCT scores were excellent 24%, good 39%, fair 32%, and poor 6%. The median total QOL score of the participants was 130 (93-144). There was no significant correlation between CO and FACT-B scores. Conclusions: The significance of CO for FACT-B in Thai women with breast cancer could not be assessed in detail because of a very low level of correlation. The results may be due to the effects of cultural background.

A study on the method of narrative in the new trend of historical drama (서사의 방법과 역사극의 새로운 방향 - <왕세자 실종사건>을 중심으로 -)

  • Kim, Yoo Mi
    • (The) Research of the performance art and culture
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    • no.18
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    • pp.283-314
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    • 2009
  • This paper is an attempt to examine historical drama which change rapidly in the manner of seeing history. Historical records are treated differently unlike in the field of modern history. Now the distinction between historical facts and fictions becomes no longer important. This change is affected by micro history, new cultural history, or post-modern history. History and narrative become interactive each other. In this respect they are no more historical drama. by Han Areum (director Suh Jae-hyung) represents this new trends. Of course, it doesn't suddenly pop up in 2005. It began in by Lee Yoon-Taek, was reinforced in by Kim Tae-Woong, and bloomed in . I intended to search important features of by following three. First is the interest about unimportant persons such as a maid of honor, an eunuch. In , they are the main characters. The author described much about those trivial people revealing the truth in different way of the existence. Second is the way of calling a past. In this piece, the past is not continuous. The past always appears at the stage by the present in the form of split which is imagination, recollection, revival. Third is a mixing genre. Comics, melodrama, and thrillers are all together in . This is a similar phenomenon to historical novel and movie of new trend. Strictly speaking, this piece isn't a history thriller. The accident of lost prince doesn't be treated importantly and the result isn't clear either. In this piece, detective genre is used for a symbol showing that writer pursuits the history, not the event. This represents well the characters of new historical drama because how historical facts are carefully recreated and constructed are important. It's enough to show the possibility to mix genre through comics and melodrama.

A Study on Gollyongpo in the Joseon Dynasty (조선시대(朝鮮時代) 곤룡포(袞龍袍) 연구)

  • Keum, Jong-Suk;Koh, Bou-Ja
    • The Research Journal of the Costume Culture
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    • v.16 no.5
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    • pp.937-954
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    • 2008
  • The Gollyongpo was worn by the King and the Crown Prince in Joseon dynasty as an ordinary wear. The research on the Gollyongpo is focused on the historic record of Joseon dynasty, Joseonwangjosillok. This study will analyze literature, paintings and relics. First, I have researched Ming's(China) representative document daminghuidian, and excavated relics from the tomb dingling. I examined the usage and characteristic, through various remaining literature data, artifacts and paintings. The Gollyongpo was worn for the various ceremonies as well as an ordinary wear. According to the periode, the style and color had changed. The King wore the red Gollyongpo with 5 clawed dragon pattern, the Crown Prince wore black one with 4 clawed pattern, and the eldest son of the Crown Prince wore black one with 3 clawed dragon emblem. After the Daehan Empire, the Emperor wore gold outfit and the Crown Prince wore red outfit. Sonyongpo recorded in the Gungjungbalgi is concerned as Gollyongpo with narrow straight sleeve, one of the Sejong University Museum's Collection. There is some Possibility that the Gollyongpo painted in Bongsado is woven with dragon design, I would leave this matter for next research task.

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EFFECT OF SUPPLEMENTATION AND PARASITIC INFECTION ON PRODUCTIVITY OF THAI NATIVE AND CROSS-BRED FEMALE WEANER GOATS I. GROWTH, PARASITE INFESTATION AND BLOOD CONSTITUENTS

  • Pralomkarn, W.;Kochapakdee, S.;Choldumrongkul, S.;Saithanoo, S.
    • Asian-Australasian Journal of Animal Sciences
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    • v.7 no.4
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    • pp.547-554
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    • 1994
  • This paper presents the effects of supplementary feeding and internal parasites on the growth rates of female weaner goats raised under improved management. A completely randomized $3{\times}3{\times}2$ factorial design was used. Factors were genotype (Thai native: TN, 75% TN $\times$ 25% Anglo-Nubian: An and 50% TN $\times$ 50% AN), feeding grazing only, low (1.0% BW/d) and high (1.5% BW/d) supplementation and parasite control (undrenched and drenched). It was shown that native goats had significantly (p<0.05) higher growth rates than did the cross-bred goats from 12-24 weeks of the trial. The growth rate of goats grazing improved pasture depended on the amount of concentrate offered as a supplement. There was no significant difference in growth rates between undrenched and drenched goats. There was no interaction effect on growth rates between the treatments. Drenched goats had significantly (p<0.01) lower egg counts per gram of gastro-intestinal nematode than did undrenched goats. There was no significant difference between the treatments for blood constituents (total protein, haemoglobin, packed cell volume, eosinophils, lymphocytes, monocytes and basophils).

GRAZING MANAGEMENT STUDIES WITH THAI GOATS I. PRODUCTIVITY OF FEMALE GOATS GRAZING NEWLY ESTABLISHED PASTURE WITH VARYING LEVELS OF SUPPLEMENTARY FEEDING

  • Kochapakdee, S.;Pralomkarn, W.;Saithanoo, S.;Lawpetchara, A.;Norton, B.W.
    • Asian-Australasian Journal of Animal Sciences
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    • v.7 no.2
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    • pp.289-294
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    • 1994
  • This report deals with the effect of levels of concentrate supplementary feeding (Nil, 0.25% BW and 0.75% BW) on the productivity of different genotypes (Thai native (TN), 25% Anglo-Nubian (AN), 50% AN and 75% AN) of female goats grazing newly established pasture in a tropical area. The major species of grass was Brachiaria mutica (33%) and of legumes was Centrosema pubescens (34%). There was no significant (p>0.05) difference between nil and 0.25% BW supplementary feeding for growth rate ($g/kg^{0.75}/d$). However, goats fed 0.75% BW supplementary feeding had significantly (p<0.01) higher growth rates than did other treatments. There was no significant (p>0.05) difference among genotypes and between age for growth rate. There was no interaction between feeding and genotype for growth rate.

Factors Influencing Usage of University Mobile Application Among University Students

  • ALJAAIDI, Khaled Salmen;BAGAIS, Omer Ali;SHARMA, Raj Bahadur
    • The Journal of Asian Finance, Economics and Business
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    • v.7 no.10
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    • pp.1129-1136
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    • 2020
  • This study investigates the factors influencing the usage of PSAU Mobile Application by the students at Prince Sattam bin Abdulaziz University (PSAU). This study used Technology Acceptance Model (TAM) as a framework to predict the factors influencing 67 students' usage of PSAU M-Application. The results of this study were consistent with the TAM framework in predicting the actual usage of the PSAU mobile application for academic activities. The results indicated a significantly positive association of the perceived ease-to-use with perceived usefulness, significantly positive associations of the perceived ease-to-use and the perceived usefulness with the attitude toward the usage of the PSAU's mobile application, a significantly positive association of the perceived usefulness with the behavioral intention toward the usage of the PSAU's mobile application, a significantly positive association of the students' attitude toward the usage of the PSAU's mobile application with the behavioral intention of using the application, and a significantly positive association of the behavioral intention with the actual usage of the PSAU's mobile application. The results of this study should be useful to educational policymakers at PSAU University and elsewhere, as there is an opportunity to enhance the existing technology or adopt new technologies for academic activities.

Sound Absorption of Natural Fiber Composite from Sugarcane Bagasse and Coffee Silver Skin

  • Wachara KALASEE;Putipong LAKACHAIWORAKUN;Visit EAKVANICH;Panya DANGWILAILUX
    • Journal of the Korean Wood Science and Technology
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    • v.51 no.6
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    • pp.470-480
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    • 2023
  • This study aimed to develop a sound-absorbing composite using sugarcane bagasse (SB) and coffee silver skin (CS) as raw materials. The composite boards were manufactured by bonding the fibers with Melamine Urea-Formaldehyde adhesive, ensuring a consistent thickness of 30 mm. Various densities were employed, namely 380, 450, and 520 kg/m3. The samples were fabricated with different fiber ratios, including SB100%, SB75% with CS25%, and SB50% with CS50%. The sound absorption coefficient (SAC) and noise reduction coefficient (NRC) were measured using the impedance tube method within a frequency range of 63-6,300 Hz. The experimental results revealed that the mixing ratio of CS exerted a notable influence on enhancing the SAC, while the density of the composite board exhibited a significant impact on increasing both the SAC and NRC. Among the densities tested, the optimal value was observed at 520 kg/m3, yielding a SAC value of 0.65 at a frequency of 1,000 Hz and an NRC value of 0.55 for the SB50-CS50 composite plate. These findings underscore the importance of considering the CS mixing ratio and composite board density when aiming to optimize sound absorption properties.