• Annals of Occupational and Environmental Medicine
• /
• 제34권
• /
• pp.29.1-29.14
• /
• 2022

Background: Hotel housekeepers are one of the most important occupational group within tourism hotel sector; various health problems related to their job have been described, above all musculoskeletal disorders. The objective of this study is to understand the experiences and perceptions of hotel housekeepers and key informants from the Balearic Islands (Spain) regarding occupational health conditions and the strategies employed to mitigate them. Methods: A qualitative study was carried out. Six focus groups with hotel housekeepers and 10 semi-structured interviews with key informants were conducted. Next, we carried out a content analysis. Results: Hotel housekeepers reported musculoskeletal disorders, anxiety and stress as main occupational health problems; health professionals underscored the physical problems. Hotel housekeepers perceived that their work (physically demanding and with repetitive movements) caused their health conditions. To solve health issues, they used medication (anti-inflammatory agents, painkillers, sedatives and anxiolytics), which allowed them to continue working; health public services, generally rated as satisfactory; individual protective equipment; ergonomics (with difficulties due to high work pace and hotel facilities) and physical activity. Two contrasting attitudes were identified regarding sick leave: HHs who refused to accept a doctor-prescribed sick leave (due to fear of being fired, sense of responsibility, ...), and those who accepted it (because they could not continue working, they prioritised health before work). Conclusions: Our results might contribute to plan improvement strategies and programs to address health problems among hotel housekeepers. These programs should include interventions, such as coping strategies for the work-related risk factors (i.e., stress) and strategies to reduce medicine consumption. Additionally, hotel facilities should adopt policies focused on making workplaces more ergonomic (i.e., furniture) and to diminish the work pace.

• Journal of Power Electronics
• /
• 제18권1호
• /
• pp.300-308
• /
• 2018

An online estimation method for wireless power transfer (WPT) systems is presented without using any measurement of the secondary side or the load. This parameter estimation method can be applied with a controlling strategy that removes both the receiving terminal controller and the wireless communication. This improves the reliability of the system while reducing its costs and size. In a wireless power transfer system with an LCCL impedance matching circuit under a rectifier load, the actual load value, voltage/current and mutual inductance can be reflected through reflected impedance measuring at the primary side. The proposed method can calculate the phase angle tangent value of the secondary loop circuit impedance via the reflected impedance, which is unrelated to the mutual inductance. Then the load value can be determined based on the relationships between the load value and the secondary loop impedance. After that, the mutual inductance and transfer efficiency can be computed. According to the primary side voltage and current, the load voltage and current can also be detected in real-time. Experiments have verified that high estimation accuracy can be achieved with the proposed method. A single-controller based on the proposed parameter estimation method is established to achieve constant current control over a WPT system.

• 한국정보디스플레이학회:학술대회논문집
• /
• 한국정보디스플레이학회 2004년도 Asia Display / IMID 04
• /
• pp.483-486
• /
• 2004

A CCD-based color uniformity measurement system was set up. Through measuring the two-dimensional brightness distributions of three primary colors on the screen, chromaticity coordinate distributions of combination gray can be obtained within a few seconds. This system can be widely used in the production of LCD projection.

• International journal of advanced smart convergence
• /
• 제10권2호
• /
• pp.10-14
• /
• 2021

Today people adopt various contents from their mobile devices which lead to numerous platforms. As technology of 5G, IOT, and smart phone develops, the number of people who create, edit, collect, and share their own videos, photos, and articles continues to increase. As more contents are shared online, the numbers of data being stolen continue to increase too. To prevent these cases, an authentication method is needed to encrypt the content and prove it as its own content. In the report, we propose a few methods to secure various misused content with secondary security. A unique private key is designed when people create new contents through sending photos or videos to platforms. The primary security is to encrypt the "Private Key" with a public key algorithm, making its data-specific "Timeset" that doesn't allow third-party users to enter. For the secondary security, we propose to use Message Authentication Codes(MACs) to certify that we have produced the content.

• International Journal of Internet, Broadcasting and Communication
• /
• 제8권1호
• /
• pp.7-18
• /
• 2016

Several authentication methods have been developed to make use of tokens in the mobile networks and smart payment systems. Token used in smart payment system is genearated in place of Primary Account Number. The use of token in each payment transaction is advantageous because the token authentication prevents enemy from intercepting credit card number over the network. Existing token authentication methods work together with the cryptogram, which is computed using the shared key that is provisioned by the token service provider. Long lifetime and repeated use of shared key cause potential brawback related to its vulnerability against the brute-force attack. This paper proposes a per-transaction shared key mechanism, where the per-transaction key is agreed between the mobile device and token service provider for each smart payment transaction. From server viewpoint, per-transaction key list is easy to handle because the per-transaction key has short lifetime below a couple of seconds and the server does not need to maintain the state for the mobile device. We analyze the optimum size of the per-transaction shared key which satisfy the requirements for transaction latency and security strength for secure payment transactions.

• Journal of Ginseng Research
• /
• 제47권2호
• /
• pp.173-182
• /
• 2023

Cancer is a global public health issue that becomes the second primary cause of death globally. Considering the side effects of radio- or chemo-therapy, natural phytochemicals are promising alternatives for therapeutic interventions to alleviate the side effects and complications. Ginsenoside Rh2 (GRh2) is the main phytochemical extracted from Panax ginseng C.A. Meyer with anticancer activity. GRh2 could induce apoptosis and autophagy of cancer cells and inhibit proliferation, metastasis, invasion, and angiogenesis in vitro and in vivo. In addition, GRh2 could be used as an adjuvant to chemotherapeutics to enhance the anticancer effect and reverse the adverse effects. Here we summarized the understanding of the molecular mechanisms underlying the anticancer effects of GRh2 and proposed future directions to promote the development and application of GRh2.

• Genomics & Informatics
• /
• 제16권2호
• /
• pp.30-35
• /
• 2018

Patient-derived xenograft (PDX) models are useful tools for tumor biology research and testing the efficacy of candidate anticancer drugs targeting the druggable mutations identified in tumor tissue. However, it is still unknown how much of the genetic alterations identified in primary tumors are consistently detected in tumor tissues in the PDX model. In this study, we analyzed the genetic alterations of three primary colorectal cancers (CRCs) and matched xenograft tissues in PDX models using a next-generation sequencing cancer panel. Of the 17 somatic mutations identified from the three CRCs, 14 (82.4%) were consistently identified in both primary and xenograft tumors. The other three mutations identified in the primary tumor were not detected in the xenograft tumor tissue. There was no newly identified mutation in the xenograft tumor tissues. In addition to the somatic mutations, the copy number alteration profiles were also largely consistent between the primary tumor and xenograft tissue. All of these data suggest that the PDX tumor model preserves the majority of the key mutations detected in the primary tumor site. This study provides evidence that the PDX model is useful for testing targeted therapies in the clinical field and research on precision medicine.

• Asian-Australasian Journal of Animal Sciences
• /
• 제31권5호
• /
• pp.650-657
• /
• 2018

Objective: The study investigated the biological functions and mechanisms for controlling cashmere growth of Liaoning cashmere goat by ovarian carcinoma immunoreactive antigen-like protein 2 (OCIAD2) and decorin (DCN) genes. Methods: cDNA library of Liaoning cashmere goat was constructed in early stages. OCIAD2 and DCN genes related to cashmere growth were identified by homology analysis comparison. The expression location of OCIAD2 and DCN genes in primary and secondary hair follicles (SF) was performed using in situ hybridization. The expression of OCIAD2 and DCN genes in primary and SF was performed using real-time polymerase chain reaction (PCR). Results: In situ hybridization revealed that OCIAD2 and DCN were expressed in the inner root sheath of Liaoning cashmere goat hair follicles. Real-time quantitative PCR showed that these genes were highly expressed in SF during anagen, while these genes were highly expressed in primary hair follicle in catagen phase. Melatonin (MT) inhibited the expression of OCIAD2 and promoted the expression of DCN. Insulin-like growth factors-1 (IGF-1) inhibited the expression of OCIAD2 and DCN, while fibroblast growth factors 5 (FGF5) promoted the expression of these genes. MT and IGF-1 promoted OCIAD2 synergistically, while MT and FGF5 inhibited the genes simultaneously. MT+IGF-1/MT+FGF5 inhibited DCN gene. RNAi technology showed that OCIAD2 expression was promoted, while that of DCN was inhibited. Conclusion: Activation of bone morphogenetic protein (BMP) signaling pathway up-regulated OCIAD2 expression and stimulated SF to control cell proliferation. DCN gene affected hair follicle morphogenesis and periodic changes by promoting transforming growth $factor-{\beta}$ ($TGF-{\beta}$) and BMP signaling pathways. OCIAD2 and DCN genes have opposite effects on $TGF-{\beta}$ signaling pathway and inhibit each other to affect the hair growth.

• Asian-Australasian Journal of Animal Sciences
• /
• 제30권3호
• /
• pp.328-337
• /
• 2017

Objective: An experiment was conducted to determine the relationship between the KAP11.1 and the regulation wool fineness. Methods: In previous work, we constructed a skin cDNA library and isolated a full-length cDNA clone termed KAP11.1. On this basis, we conducted a series of bioinformatics analysis. Tissue distribution of KAP11.1 mRNA was performed using semi-quantitative reverse transcription polymerase chain reaction (RT-PCR) analysis. The expression of KAP11.1 mRNA in primary and secondary hair follicles was performed using real-time PCR (real-time polymerase chain reaction) analysis. The expression location of KAP11.1 mRNA in primary and secondary hair follicles was performed using in situ hybridization. Results: Bioinformatics analysis showed that KAP11.1 gene encodes a putative 158 amino acid protein that exhibited a high content of cysteine, serine, threonine, and valine and has a pubertal mammary gland) structural domain. Secondary structure prediction revealed a high proportion of random coils (76.73%). Semi-quantitative RT-PCR showed that KAP11.1 gene was expressed in heart, skin, and liver, but not expressed in spleen, lung and kidney. Real time PCR results showed that the expression of KAP11.1 has a higher expression in catagen than in anagen in the primary hair follicles. However, in the secondary hair follicles, KAP11.1 has a significantly higher expression in anagen than in catagen. Moreover, KAP11.1 gene has a strong expression in inner root sheath, hair matrix, and a lower expression in hair bulb. Conclusion: We conclude that KAP11.1 gene may play an important role in regulating the fiber diameter.

• 한국지역지리학회지
• /
• 제18권2호
• /
• pp.232-251
• /
• 2012

이 연구는 영국 국가교육과정의 개정에 따른 지리 학습프로그램의 변화와 그 함의를 밝히고자 한 것이다. 2008년과 2011년부터 각각 시행된 중등 및 초등 국가교육과정은 1995년과 2000년에 이어 세 번째 개정으로서 그 이전보다 편제 면에서나 내용 면에서나 획기적인 변화를 보이고 있다. 특히, 초등 국가교육과정은 6개의 학습영역으로 재편 되었는데, 기존의 KS1-2 지리는 역사 및 시민성과 함께 '역사적, 지리적, 사회적 이해'라는 학습영역에 통합되어, 처음으로 통합사회과의 출범을 알리는 계기가 되었다. 그리하여 현재 영국 국가교육과정에서는 지리는 KS3에서만 기초 교과로서 그 이름을 유지하고 있다. 그럼에도 불구하고 국가교육과정은 여전히 학습프로그램과 성취목표로 구성되어 있다. 그러나 학습프로그램의 구성 체제와 그 내용에 있어서는 매우 큰 변화가 있었다. 초등의 경우 학습프로그램이 '교육과정 목표-학습영역의 중요성-본질적 지식-핵심기능-범교과적 학습-학습의 폭-교육과정의 계열'로, 중등의 경우 '교육과정 목표-교과의 중요성-핵심개념-핵심프로세서-범위와 내용-교육과정 기회'로 재구조화되었다. 이 연구는 이와 같은 새로운 지리 학습프로그램의 항목별 특징과 효과적인 지리교육과정 계획을 위한 함의를 도출하였다.