• Communications for Statistical Applications and Methods
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• v.29 no.4
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• pp.421-439
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• 2022

Phase I dose-finding trials are essential in drug development. By finding the maximum tolerated dose (MTD) of a new drug or treatment, a Phase I trial establishes the recommended doses for later-phase testing. The primary toxicity endpoint of interest is often a binary variable, which describes an event of a patient who experiences dose-limiting toxicity. However, there is a growing interest in dose-finding studies regarding non-binary outcomes, defined by either the weighted sum of rates of various toxicity grades or a continuous outcome. Although several novel methods have been proposed in the literature, accessible software is still lacking to implement these methods. This study introduces a newly developed R package, UnifiedDoseFinding, which implements three phase I dose-finding methods with non-binary outcomes (Quasi- and Robust Quasi-CRM designs by Yuan et al. (2007) and Pan et al. (2014), gBOIN design by Mu et al. (2019), and by a method by Ivanova and Kim (2009)). For each of the methods, UnifiedDoseFinding provides corresponding functions that begin with next that determines the dose for the next cohort of patients, select, which selects the MTD defined by the non-binary toxicity endpoint when the trial is completed, and get oc, which obtains the operating characteristics. Three real examples are provided to help practitioners use these methods. The R package UnifiedDoseFinding, which is accessible in R CRAN, provides a user-friendly tool to facilitate the implementation of innovative dose-finding studies with nonbinary outcomes.

• Journal of Broadcast Engineering
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• v.27 no.5
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• pp.718-727
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• 2022

The Korean domestic cartoon industry has grown explosively by 65% compared to the previous year. Then the market size is expected to exceed KRW 1 trillion. However, excessive work results in health deterioration. Moreover, this working environment makes the production of human resources insufficient, repeating a vicious cycle. Although some tasks require creation activity during cartoon production, there are still a lot of simple repetitive tasks. Therefore, this study aimed to develop a method for creating a character pose through human pose estimation (HPE). The HPE is to detect key points for each joint of a user. The primary role of the proposed method was to make each joint of the character match that of the human. The proposed method enabled us to create the pose of the two-dimensional cartoon character through the results. Furthermore, it was possible to save the static image for one character pose and the video for continuous character pose.

• Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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• v.7 no.1
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• pp.265-276
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• 2017

Korean petroglyphs have been found over a lot of ruins through nation-wide regions including Daegok-ri Bangudae and Cheonjeon-ri in Ulsan. In this paper, we present an information system for Korean petroglyph ruins named KPetro which supports the dedicated camera application and the timeline service. The system provides the services for searching and updating information in various ways over the primary database constructed with the data on petroglyph ruins, which are collected by the Bangudae Petroglyph Institute. In addition, through the camera application developed for the system, users can easily add photos to the appropriate petroglyph ruin according to the GPS information of the location where those photos are taken. Also, the system provides the timeline service showing the photos for a specific petroglyph ruins in order of shooting time. To support both mobile and desktop environments, KPetro provides its functions in a web browser using the HTML5 standard technology and the JavaScript language, enabling the system to be adaptable to various user devices and extendable for its functionalities.

• The Korean Journal of Franchise Management
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• v.7 no.1
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• pp.21-29
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• 2016

Purpose - The primary purpose of this study is to employ effective marketing methods using market segmentation of coffee shops by determining how motivations to visit coffee shops have different impacts on demographic profile of visitors and characteristics of coffee shop visits, so as to draw out a better understanding of customers of coffee market. Research design, data, and methodology - Data were collected using surveys of self-administered questionnaires toward coffee shop users in Daejeon, Korea. A number of samples used in data analysis were 253 excluding unusable responses. The data were analyzed through frequency, reliability, and factor analysis using SPSS 20.0. Factor analysis was conducted through the principal component analysis and varimax rotation method to derive factors of one or more eigen values. In addition, the cluster analysis, multivariate ANOVA, and cross-tab analysis were used for the market segmentation based on the types of motivation for coffee shop visits. The process of the cluster analysis is as follows. Four clusters were derived through hierarchical clustering, and k-means cluster analysis was then carried out using mean value of the four clusters as the initial seed value. Result - The factor analysis delineated four dimensions of motivation to visit coffee shops: ostentation motivation, hedonic motivation, esthetic motivation, utility motivation. The cluster analysis yielded four clusters: utility and esthetic seekers, hedonic seekers, utility seekers, ostentation seekers. In order to further specify the profile of four clusters, each cluster was cross tabulated with socio-demographics and characteristics of coffee shop visits. Four clusters are significantly different from each other by four types of motivations for coffee shop visits. Conclusions - This study has empirically examined the difference in demographic profile of visitors and characteristics of coffee shop visits by motivation to visit coffee shops. There are significant differences according to age, education background, marital status, occupation and monthly income. In addition, coffee shops use pattern characterization in frequency of visits to coffee shops, relationships with companion, purpose of visit, information sources, brand type, average expense per visit, important elements of selection attribute were significantly different depending on motivations for coffee shop visits.

• Journal of Gastric Cancer
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• v.24 no.1
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• pp.108-121
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• 2024

Anastomotic leaks and fistulas are significant complications of gastric surgery that potentially lead to increased postoperative morbidity and mortality. Surgical intervention is reserved for cases with severe symptoms or hemodynamic instability; however, surgery carries a higher risk of complications. With advancements in endoscopic treatment options, endoscopic approaches have emerged as the primary choice for managing these complications. Endoscopic clipping is a traditional method comprising 2 main categories: through-the-scope clips and over-the-scope clips. Through-the-scope clips are user friendly and adaptable to various clinical scenarios, whereas over-the-scope clips can close larger defects. Another promising approach is endoscopic stent insertion, which has shown a high success rate for leak closure, although vigilant monitoring is required to monitor stent migration. Infection control is essential in post-surgical leakage cases, and endoscopic internal drainage provides a relatively safe and noninvasive means to manage fluids, contributing to infection control and wound healing promotion. Endoscopic suturing offers full-thickness wound closure, but requires additional training and endoscopic versatility. As a promising tool, endoscopic vacuum therapy potentially surpasses stent therapy by draining inflammatory materials and closing defects. Furthermore, the use of tissue sealants, such as fibrin glue and cyanoacrylate, has been reported to be effective in selected situations. The choice of endoscopic device should be tailored to individual cases and specific patient conditions, with careful consideration of the nature of the defect. Further extensive studies involving larger patient populations are required to provide more robust evidence on the efficacy of endoscopic approach in managing post-gastric anastomotic leaks.

• Journal of the Korean Society of Safety
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• v.39 no.1
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• pp.41-54
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• 2024

Efforts to reduce on-site safety incidents have expanded, leading to active research in this domain. However, a systematic analysis to improve the utility of technology is lacking. In this study, we conducted a survey on the various institutional and technical improvement measures to promote the application of smart construction safety technology over three years after the implementation of the "Smart Safety Equipment Support Project." The results showed that financial constraint was the primary obstacle in the adoption of this innovation. Fostering a flexible environment in the utilization of management fees and financial support of projects was determined to aid in the extensive application of the technology. Ensuring cost efficiency and user-friendliness were principally necessary for technical enhancements in the smart construction safety technology. Technologies, such as VR/AR safety education, real-time location tracking, wearable devices, and innovation on streamlining safety-related work efficiency, had been anticipated to contribute to on-site safety. Operating a smart safety control center was expected to be beneficial in the systematic securing of data and reduction of safety blind spots. Effective methods had been suggested to overcome the barriers that hindered the development and application of smart construction safety technology. This study facilitates in the technological improvements in this field.

• Nutrition Research and Practice
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• v.18 no.2
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• pp.294-307
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• 2024

BACKGROUND/OBJECTIVES: Dietitians frequently use nutrition education tools to facilitate dietary counselling sessions. Nevertheless, these tools may require adaptation to keep pace with technological advancements. This study had a 2-fold purpose: first, to identify the types of nutrition education tools currently in use, identify their limitations, and explore dietitians' perspectives on the importance of these tools; second, to investigate the features that dietitians prefer in digital nutrition education tools. SUBJECTS/METHODS: A semi-structured face-to-face interview was conducted among 15 dietitians from selected public hospitals, primary care clinics, and teaching hospitals in Malaysia. Inductive thematic analysis of the responses was conducted using NVivo version 12 software. RESULTS: Most dietitians used physical education tools including the healthy plate model, pamphlets, food models, and flip charts. These tools were perceived as important as they facilitate the nutrition assessment process, deliver nutrition intervention, and are time efficient. However, dietitians described the current educational tools as impersonal, outdated, limited in availability due to financial constraints, unhandy, and difficult to visualise. Alternatively, they strongly favoured digital education tools that provided instant feedback, utilised an automated system, included a local food database, were user-friendly, developed by experts in the field, and seamlessly integrated into the healthcare system. CONCLUSION: Presently, although dietitians have a preference for digital educational tools, they heavily rely on physical nutrition education tools due to their availability despite the perception that these tools are outdated, impersonal, and inconvenient. Transitioning to digital dietary education tools could potentially address these issues.

• Asia-Pacific Journal of Business
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• v.14 no.4
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• pp.163-174
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• 2023

Purpose - This study examines the effect of consumers' motivations on the perception and purchase intentions of electric cars. Specifically, it empirically analyzes how moral motivations based on personal environmental values and norms in car usage and purchasing influence the perceived usefulness and purchase intentions of electric cars. Furthermore, it investigates whether the influence of moral motivations on perceived usefulness and purchase intentions varies according to the user's driving characteristics. Design/methodology/approach - An online survey was conducted with 234 respondents, by setting criteria for participants as car owners or primary car users within their households, ensuring the sample composition was not biased in terms of the presence or absence of experience with eco-friendly cars. Findings - The research findings indicate that perceived usefulness mediates the effect of consumers' moral motivations on their intention to purchase electric cars. The results of the moderating effect of driving distance on perceived usefulness revealed a significant interaction effect; however, there was no significant interaction effect on purchase intentions. Specifically, for individuals with shorter driving distances, as consumers' moral motivations increase, their perception of the usefulness of electric cars also increases. In contrast, for those with longer driving distances, the increase in perceived usefulness due to moral motivations shows a decreasing trend. Research implications or Originality - This study considered individual driving characteristics that previous research on electric vehicle adoption overlooked, and suggested that setting specific communicating points for electric cars according to driving distance levels might be effective. Lastly, it proposes directions for future research that motivations influencing eco-friendly vehicle purchases may differ based on driving characteristics

• International Journal of Computer Science & Network Security
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• v.24 no.9
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• pp.127-134
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• 2024

The acute respiratory infection known as a coronavirus (COVID-19) may present with a wide range of clinical manifestations, ranging from no symptoms at all to severe pneumonia and even death. Expert medical systems, particularly those used in the diagnostic and monitoring phases of treatment, have the potential to provide beneficial results in the fight against COVID-19. The significance of healthcare mobile technologies, as well as the advantages they provide, are quickly growing, particularly when such applications are linked to the internet of things. This research work presents a knowledge-based smart system for the primary diagnosis of COVID-19. The system uses symptoms that manifest in the patient to make an educated guess about the severity of the COVID-19 infection. The proposed inference system can assist individuals in self-diagnosing their conditions and can also assist medical professionals in identifying the ailment. The system is designed to be user-friendly and easy to use, with the goal of increasing the speed and accuracy of COVID-19 diagnosis. With the current global pandemic, early identification of COVID-19 is essential to regulate and break the cycle of transmission of the disease. The results of this research demonstrate the feasibility and effectiveness of using a knowledge-based smart system for COVID-19 diagnosis, and the system has the potential to improve the overall response to the COVID-19 pandemic. In conclusion, these sorts of knowledge-based smart technologies have the potential to be useful in preventing the deaths caused by the COVID-19 pandemic.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.24 no.4
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• pp.1-7
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• 2024

Traditional security model design presents two primary issues. First, these models have been developed and implemented with a technology-centered approach rather than considering human factors. Such structures can be undermined by cognitive vulnerabilities like psychological resistance within organizations and user errors. Second, these models are typically designed based on network perimeter security. This design is unsuitable for the boundary-less remote work environments rapidly becoming prevalent due to the Fourth Industrial Revolution and the COVID-19 pandemic. This paper proposes an approach to address these limitations by integrating human-centered threats within the Zero Trust security model, a state-of-the-art boundary-less security framework. By doing so, we suggest a robust security model design that can protect against both technical and human-centered threats.