• Imaging Science in Dentistry
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• 제35권4호
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• pp.235-239
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• 2005

A very uncommon tumor, primary intraosseous carcinoma (PIOC), is a carcinoma arising within the jaw. The definite diagnosis of PIOC is often difficult as the lesion must be distinguished from alveolar carcinoma that may invade the bone from the overlying soft tissues or from the tumors that have metastasized to the jaw from a distant site. A case of PIOC arising in the mandible is presented. The clinical, radiologic, and histologic features are described. This rare lesion should be considered in any differential diagnosis of a jaw radiolucency.

• Journal of Gastric Cancer
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• 제4권3호
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• pp.186-191
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• 2004

Primary small-cell carcinomas of the stomach are rare and aggressive malignancies with poor survival rates. Preoperative diagnosis is difficult and a standard treatment is not yet established. We have recently experienced two cases of a primary small-cell carcinoma of the stomach. The first case was a 65-year-old man with epigastric soreness. Endoscopic biopsy showed an adenocarcinoma. He underwent a radical subtotal gastrectomy with D2 lymph-node dissection. Pathology revealed a collision tumor of a smallcell carcinoma and an adenocarcinoma with submucosal invasion and with metastasis in 20 out of 48 lymph nodes (T1N3M0). The second case was a 64-year-old man with epigastric soreness. Endoscopic biopsy revealed a small-cell carcinoma. There was no evidence of a primary tumor in the lung. A radical subtotal gastrectomy with D2 lymph-node dissection was performed. Pathology showed a pure smallcell carcinoma with proper muscle invasion and with metastasis in 1 out of 36 lymph nodes (T2aN1M0).

• Journal of Chest Surgery
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• 제24권6호
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• pp.631-635
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• 1991

Spontaneous pneumothorax is a rare manifestation of primary lung cancer and it is even more rare as an initial manifestation. Recently we have experienced three cases of lung cancer presenting initially as spontaneous pneumothorax. These three cases involved 2 men and one woman with an average age of 70 years [66 - 74years]. Lung cancer was discovered by explothoracotomy in two cases and by endoscopic biopsy in one case. In pathologic cell types, the one was alveolar cell carcinoma and the others were squamous cell carcinoma. We report these three cases of primary lung cancer presenting initially as spontaneous pneumothorax with review of the literatures.

• 대한두경부종양학회지
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• 제16권2호
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• pp.216-219
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• 2000

Small cell carcinoma usually occurs in lung, but extrapulmonary small cell carcinomas can occur in any sites of body. Most sites of extrapulmonary small cell carcinoma reported were esophagus. And small cell carcinomas occurred in head and neck area were reported rarely. Extrapulmonary small cell carcinoma could be diagnosed when there is no evidence of primary lung lesion on chest X-ray, CT scan of chest and bronchoscopy. The authors experienced a case of small cell carcinoma of left submandibular lymph node in 64-year-old male patient. Biopsy specimen showed poorly differentiated carcinoma but immunohistochemical study showed small cell carcinoma. The chest X-ray and CT scan of chest showed no evidence of primary lung lesion. The patient received chemotherapy(etoposide plus cisplatin) and concurrent chemoradiotherapy using weekly taxol which resulted in good clinical remission. He is still alive 8 months after diagnosis without evidence of lung disease. We report our case with a brief review of literatures.

• Radiation Oncology Journal
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• 제14권1호
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• pp.61-67
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• 1996

목적 : 접형동에 발생하는 일차성 암은 매우 드물어 전체 부비동 악성종양의 $0.3\%$를 차지한다. 접형동암이 드물게 발생되므로 많은 환자들을 분석하여 얻은 치료결과나 생존기간의 통계가 지금까지도 보고되지 않았다. 이에 본원에서 치료를 시행했던 접형동암 환자 1예의 치료경과를 보고하고자 한다. 증례 보고 : 일부 증례보고들과 소수의 환자들을 대상으로 했던 연구들을 재검토한 한 보고에 따르면 2년 생존율이 $7\%$였다. 본 증례는 접형동암으로 진단된 후 지금까지 29개월동안 생존하고 있다. 또한 척수내 전이는 암환자에서 드문 합병증인데 본 증례에서는 접형동암으로 진단된 후 25개월 만에 갑자기 하지 마비증세와 배뇨곤란을 호소하여 흉추부위를 MRI촬영한 결과 척수내 전이성종양을 3번 4번 흉추부위에서 관찰할 수 있었고 척수공동증을 그 이하부위에 동반하고 있었다. 저자들은 접형동암환자에서 척수공동증을 동반한 척수내 전이소견을 보인 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

• 대한골관절종양학회지
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• 제18권1호
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• pp.1-6
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• 2012

목적: Marjolin 궤양으로 발생한 편평 상피암의 치료결과에 대해 원발성 편평 상피암과 비교 분석하고자 한다. 대상 및 방법: Marjolin 궤양에 의한 편평 상피암으로 치료받았던 14예를 대상으로 하였으며, 같은 기간 치료받았던 원발성 편평 상피암 20예를 대조군으로 하였다. 평균 연령은 61.2세였으며, 남자 24예였고, 여자가 10예였다. 두 군간의 발생 부위, 조직학적 분류, 병기, 치료 방법, 전이, 재발, 생존율에 대해 비교 분석하였다. 결과: 평균 추시 기간은 54.8개월(12-168개월)이었다. 국소 재발은 6예에서 발생하였고, 5예는 Marjolin 궤양 군에서, 나머지 1예는 원발성 편평 상피암 군에서 발생하였다. 최초 진단 후 국소 재발까지의 평균 기간은 9개월(2-20개월)이었다. 전이는 총 6예에서 발생하였는데 이들 중 2예(14.3%)는 Marjolin 궤양 군에서, 나머지 4예(20.0%)는 원발성 편평 상피암 군에서 발생하였다. 전이 또는 국소 재발은 총 10예에서 발생하였는데 이들 중 6예는 Marjolin 궤양 군에서, 나머지 4예는 원발성 편평 상피암 군에서 발생하였다. 5년 무병 생존률은 Marjolin 궤양 군에서는 64.3%였고, 원발성 군에서는 95%였다. 결론: Marjolin 궤양에 동반된 편평 상피암은 적극적인 치료에도 불구하고 높은 재발율 및 사망률을 보이므로, 치료 결과를 향상시키는 새로운 치료법에 대한 연구가 요구된다.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제33권5호
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• pp.440-444
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• 2011

Mucoepidermoid carcinoma generally arises from salivary glands and represents 5~10% of all salivary tumors. Arising within the jaws as primary central bony lesions, central mucoepidermoid carcinomas are extremely rare, accounting for only 2~3% of all mucoepidermoid tumors. Central mucoepidermoid carcinoma of the mandible was first reported in 1939 and since then approximately 100 cases have been documented in the literature. Several hypotheses have been proposed to explain the pathogenesis of intraosseous salivary tumors. The most likely source of most intraosseous tumors is odontogenic epithelium. Waldron and Mustoe suggested that central mucoepidermoid carcinoma be included in primary intraosseous carcinoma of the jaw. We report here on a case of central mucoepidermoid carcinoma affecting the mandible and discuss the clinical, radiographic, and histological findings.

• Journal of Chest Surgery
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• 제2권1호
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• pp.13-18
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• 1969

A clinical evaluation was done on a total of 41 cases of primary bronchogenic carcinoma, which came to the department of thoracic surgery, Chonnam University Hospital for the period of 5 years from May 1964, and the various factors led the patients to an inoperable stage were searched. The incidence ratio of male to female was 5.8:1 and the age group of fifty and sixty decade occupied 78% of the total. The subjective symptoms of the patients were cough with or without sputum [83%], chest pain or chest discomfort [76%], and a few incidence of bloody sputum and hemoptysis. The histological findings were 40% of squamous cell carcinoma, 35% of adenocarcinoma and 25% of anaplastic carcinoma, including 5 cases of unclassified bronchogenie carcinoma in scalene biopsy. 12 cases [29%] of a total of 41 cases received thoracotomy, but 8 cases among them were operable and 4 cases inoperable. The rest of 29 cases [71%] could not receive thoracotomy because of the various contraindication. 23 cases [70%] out of inoperable 33 cases had wasted time over 2 months duration for an operation owing to physicians` misdiagnosis of bronchogenic carcinoma as pulmonary tuberculosis, chronic lung abscess, asthma, pleurisy, pneumonia. common cold, neuralgia in order. The delaying factors led the patients to an inoperable stage were physicians misdiagnosis of bronchogenic carcinoma due to non-specific symptoms and signs of the patients, old aged patients dependance on herb medicine, and poor economical condition of the patients.

• 대한두경부종양학회지
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• 제35권2호
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• pp.45-49
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• 2019

Large cell neuroendocrine carcinoma is a rare epithelial neuroendocrine malignancy and is preferentially located in gastrointestinal tract and pancreas. Cases of large cell neuroendocrine carcinoma have been reported in many other locations, including the thymus, gallbladder, prostate, larynx, salivary glands, nasopharynx, tonsil and mastoid. However, primary sinonasal large cell neuroendocrine carcinoma never have been reported in Korea. We experienced a case of primary large cell neuroendocrine carcinoma arising from left maxillary sinus recently. A 82-year-old male patient presented with nasal obstruction and epistaxis. The biopsy revealed large cell neuroendocrine carcinoma with poor differentiation. After a general evaluation, the patient was staged as cT3N0M0. The patient was treated by combined radiotherapy and chemotherapy. We report this rare case with literature review.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제12권1호
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• pp.121-126
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• 1990

Primary squamous cell carcinoma occuring in the salivary glands involves a grave prognosis since the tumor exhibit infiltrative properties, metastasizes early and recurs readily. But it is so rare that the clinician may see only a few in a lifetime of practice. The following report describes a case of primary squamous cell carcinoma arising from the submaxillary gland treated by combined therapy including surgery, radiotherapy and hyperthermia. The biologic behavior of the tumor was quite abnormal that immediate recurrence was noticed in two weeks after surgery. The progress was dismal and the disease became overwhelming before long.