대한두경부종양학회지 (Korean Journal of Head & Neck Oncology)

  • 제35권2호
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  • Pages.45-49
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  • 2019
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  • 1229-5183(pISSN)
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  • 2586-2553(eISSN)
대한두경부종양학회 (The Korean Society for Head and Neck Oncology)
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상악동에 발생한 대세포 신경내분비 암종 1례

A Case of Large Cell Neuroendocrine Carcinoma of the Maxillary Sinus

  • 이윤재 (한양대학교 의과대학 이비인후-두경부외과학교실) ;
  • 정진혁 (한양대학교 의과대학 이비인후-두경부외과학교실) ;
  • 오영하 (한양대학교 의과대학 병리과학교실) ;
  • 지용배 (한양대학교 의과대학 이비인후-두경부외과학교실)
  • Lee, Yun Jae (Department of Otorhinolaryngology-Head and Neck Surgery, Hanyang University College of Medicine) ;
  • Jeong, Jin Hyeok (Department of Otorhinolaryngology-Head and Neck Surgery, Hanyang University College of Medicine) ;
  • Oh, Young Ha (Department of pathology, Hanyang University College of Medicine) ;
  • Ji, Yong Bae (Department of Otorhinolaryngology-Head and Neck Surgery, Hanyang University College of Medicine)
  • 투고 : 2019.08.12
  • 심사 : 2019.11.07
  • 발행 : 2019.11.30
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초록

Large cell neuroendocrine carcinoma is a rare epithelial neuroendocrine malignancy and is preferentially located in gastrointestinal tract and pancreas. Cases of large cell neuroendocrine carcinoma have been reported in many other locations, including the thymus, gallbladder, prostate, larynx, salivary glands, nasopharynx, tonsil and mastoid. However, primary sinonasal large cell neuroendocrine carcinoma never have been reported in Korea. We experienced a case of primary large cell neuroendocrine carcinoma arising from left maxillary sinus recently. A 82-year-old male patient presented with nasal obstruction and epistaxis. The biopsy revealed large cell neuroendocrine carcinoma with poor differentiation. After a general evaluation, the patient was staged as cT3N0M0. The patient was treated by combined radiotherapy and chemotherapy. We report this rare case with literature review.

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참고문헌

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