• Tuberculosis and Respiratory Diseases
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• 제48권6호
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• pp.837-852
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• 2000

연구배경 : 이 연구는 우리나라 각 기초자치단체에서 발행하는 "통계연보" 등을 활용하여 결핵관리사업의 성과를 결핵예방사업, 환자발견 및 지속관리사업, 그리고 결핵 치료사업 측면에서 소규모 지역간 사계열분석 모형에 의해 연도별 인구천명당 결핵등록률 및 결핵 치료순응도 등의 성과지표로 산출하여 비교분석하고 이에 영향을 미치는 요인을 규명하고자 하였다. 방법 : 전국 234개 시 군 구 기초자치단체별로 발간된 "통계연보"나 광역자치단체별 "통계연보"를 원주시청 행정자료실, 강원도청 행정자료실, 통계청 민원실 등을 방문, 1980년도부터 2000년도까지 순차적으로 열람하여 결핵관리사업등 관련 정보를 지난 1년여동안 추적 조사하였다. 결핵관리사업의 성과지표인 연도별 결핵유병률 등을 산정, 이를 종속변수로 하여 다중 희귀모형을 구축하여 Micro TSP와 SAS 패키지를 이용하여 확률론적안 시계열분석을 하였다. 결과 : 1998년까지의 지역별 현황을 비교하면, 인구지표 중 인구이동률을 제외한 나머지 변수들의 경우 모두 구지역, 시지역, 군지역의 순으로 유의하게 감소하였다. 사회 경제학적 지표로는 인구천명당 자동차 등록대수, 지방세, 담배소비세 모두 시 군 구지역간에 유의한 차이를 보였다. 또한 보건의료지표는 시 군 구지역간 인구천명당 의사수 및 병상수 모두 통계적으로 유의하게 지역 규모의 크기에 따라 감소하였다. 지역별 관련 결핵지표의 시계열 분포의 변화를 비교하면, BCG접종률의 경우 1980년부터 1984년까지 약간의 증가 추세를 보이다가 그 이후 1993년도까지는 일정한 평형 수준 (plateau state) 을 유지한 이후 다시 감소추세를 보였다. 1985년 이전에는 시지역이, 1985년 이후에는 군지역의 접종률이 타지역에 비해 유의하게 높았다. 폐결핵양성자수 시점유병률, 폐결핵 음성자수 시점유병률 및 결핵사망률의 분포를 보면, 세가지 결핵지표 모두 1981년 이후 지속적으로 감소하는 영향을 보여주되, 군지역이 가장 높았고 시간이 경과할수록 시 군 구지역간 차이도 점차 줄어들었다. 이는 지역 특성상 민간의료기관의 분포가 적은 군 지역에서의 결핵등록 및 관리사업이 상대적으로 시 구(광역도시)지역보다 보건소 중심으로 용이하게 운영되어지고 있음을 시사한다. 결핵 치료순응도의 경우 기간유병률이나 사망률과는 반대로 1982년 이후 점차 증가하는 추세였다. 결론 : 이 연구결과는 현재 보건소 중심으로 관리되어 매년 집계, 보고, 발간되는 시 군 구 기초자치단체별 "통계연보"의 결핵보건사업 결과정보에 대한 이용의 실증연구에 해당된다. 따라서 지난 제7차까지 시행해 오던 전국결핵실태조사 대신에 향후 시행될 결핵정보 감시체계 운영등의 기초자료로서 가능성을 제공해주고 있다. 결국 이를 바탕으로 결핵관리사업과 관련 지역 특성에 맞는 지역보건의료계획 수립의 기초자료 및 정부의 국가결핵보건사업 기획의 근거를 제공함으로써 결핵관리 대책 수립시 우선순위 결정과 예산배분, 기대효과 산정에 필수적인 정보로 활용되기를 기대한다.

• Preventive Nutrition and Food Science
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• 제14권4호
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• pp.329-334
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• 2009

The effects of drying conditions on the antioxidant activities, luteolin, and volatile compounds of Chrysanthemi Flos flowers were evaluated. The flowers were dried with hot-air or far-infrared radiation at 40${^{\circ}C}$, 50${^{\circ}C}$ and 60${^{\circ}C}$, respectively, to reach 22$\pm$1% of moisture content. Each 10 g of the dried flowers were extracted with 100 mL of 95% ethanol. Increasing temperature in hot-air dried (HAD) conditions increased the antioxidant activities of the flower extracts. However, increasing temperature in far-infrared dried (FID) conditions decreased the antioxidant activities of the extracts. Luteolin, one of main flavonoids of Chrysanthemi Flos flowers, was present in the highest content at 60${^{\circ}C}$ FID flowers with a value of 139 $\mu$g/mL. Thirteen volatile compounds including camphor and β-caryophyllene were identified in chromatograms. Higher amount of the volatiles were found at 50${^{\circ}C}$ HAD and 40${^{\circ}C}$ FID. The results indicated that the antioxidant activities and volatile compounds of Chrysanthemi Flos flowers were significantly affected by drying conditions.

• 약학회지
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• 제56권2호
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• pp.116-125
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• 2012

Local pharmaceutical companies in Korea, which have grown focusing on domestic markets, have recently faced difficulties such as market saturation, price control policies and market-opening pressures by FTA. It seems to be an urgent issue for them to export pharmaceuticals to developed countries comprising the greater part of the global pharmaceutical market. Hence, this research was conducted to investigate and benchmark the strategies employed by India industry for the successful access to the global pharmaceutical markets. Drug policies as well as their influences on pharmaceutical market changes between India and Korea for the last 40 years have been searched and the differences have been comparatively analyzed. The pharmaceutical industry of India has the following strengths: low costs; experienced labor pool; excellent reverse-engineering skills; powerful IT; marketing capability; and established distribution network. After 2000, consolidations, M&A and alliances with domestic and multinational companies have been sharply increased in the industry of India. Indian companies unfolding both competition and cooperation with multinational corporations currently move up the value-added chain, and this enthusiastic strategy should be learned by local pharmaceutical companies.

• Preventive Nutrition and Food Science
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• 제9권1호
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• pp.98-106
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• 2004

Tomatoes and tomato products are the major source of lycopene in the diet. The bioavailability of lycopene is different in raw tomatoes compared to processed tomato products. This is due to the chemical and physical properties of the different lycopene isomers. All-trans-lycopene is found in raw tomatoes and is a poor bioavailable source, whereas, processed tomato products are more bioavailable because they contain more cis-isomers. Heat and mechanical processing of tomatoes induces rupture of the cell walls, thereby releasing lycopene from its food matrix. Heat processing also induces cis-trans isomerization and disrupts protein-carotenoid complexes. Many dietary components also impact lycopene bioavailability, like the amount and type of fat present with the intake and processing of tomato products, the amount and type of fiber present, and the interaction between carotenoids. Fundamentally, anything that enhances formation and incorporation of lycopene in bile acid micelles increases bioavailability, and the opposite is true in that anything that interferes with micelle formation decreases bioavailability.

• 한국병원경영학회지
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• 제4권2호
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• pp.21-40
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• 1999

One Diagnosis Related Group(DRG) pilot study participating hospital was measured and analyzed to see if there were any changes after the DRG program. It was implemented in consideration of medical service utilization, hospital charges, and non-covered medical service charges by insurance in all Cesarean section cases by reviewing medical records for 3 years, including 1 year before pilot study as well as 1 and 2 years after, respectively. The results were as follows: First, the use of intramuscular antibiotics decreased statistically significantly, whereas intravenous use did not. Second, the administration period and charges of antianemic medication decreased significantly, where the prescription was appropriate. Third, the length of hospital stay decreased statistically significantly. Fourth, there were significant statistical differences in cost sharing between the insured and the insurer: cost sharing of the insured was reduced, whereas the share of the insurer increased. However, there was no change in the quality of care. Fifth, there were no statistically significant changes in the Cesarean section rate. As a result, if the fee schedule is reasonably high, hospitals can provide quality care. This DRG pilot study resulted expected outcomes: by paying a higher fee schedule than fee-for-service, then hospitals can provide quality care to their patients and increase hospital profits.

• 농촌의학ㆍ지역보건
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• 제42권1호
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• pp.24-35
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• 2017

이 연구의 목적은 한국형 일차의료 평가 도구(KPCAT)를 이용하여 한 농촌 지역 보건소의 일차의료의 질을 평가하는 것이다. 또 이 연구에서는 KPCAT 적용 및 결과 해석과 관계된 몇 가지 방법론적 이슈를 검토하였다. 농촌 보건소 진료 의사에게 4회 이상 진료받은 환자 79명이 KPCAT 설문에 응답하였다. 응답자의 특성을 빈도와 백분율, 중앙값과 사분위 범위, 평균과 표준 편차로 제시하였다. 일차의료의 질은 KPCAT 총점과 영역별 점수의 중앙값과 사분위 범위로 제시하였고 최댓값과 최솟값, 기대 점수와 함께 방사형 도표로 제시하였다. KPCAT 문항별 점수와 중앙값과 사분위 범위, 기대 점수 이상 응답자 비율, 잘 모름 응답자 비율을 제시하였다. 연구 대상 농촌 지역 보건소 일차의료 질의 중앙값과 사분위 범위는 각각 45점, 16점이었다. KPCAT 영역별 점수 중앙값이 기대 점수에 이른 영역은 최초 접촉 하나였다. KPCAT 문항별 점수가 기대 점수 이상인 응답자 비율이 50% 미만인 문항은 포괄성 4문항 중 2개, 조정 기능 3문항 전부, 전인적 의료 5문항 중 2개, 가족 및 지역 사회 지향성 4문항 전부였다. 잘 모름 응답의 처리 방침 개선, 잘 모름 응답률이 높은 문항의 타당성 검토, 응답 척도의 내용과 점수의 일치 등이 방법론적 개선 과제였다. 농촌 지역 보건소 일차의료의 질은 개선할 여지가 많았다. 특히 조정 기능과 가족 및 지역 사회 지향성 영역의 개선 필요성이 두드러졌다. KPCAT의 방법론적 개선을 통하여 타당하고 신뢰성 있는 일차의료 평가가 이루어지기를 기대한다.

• 환경영향평가
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• 제2권2호
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• pp.1-11
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• 1993

Most developing countries are experiencing rapid urbanization and the associated growth of industry and services. Cities are currently absorbing two-thirds of the total population in the developing world. Korea has about 85 percent of urban dwellers. World population will shift from being predominantly rural to predominantly urban around the turn of the century. Although cities play a key role in development process and make more than a proportionate contribution to national economic growth, especially cities are also the main catalysts of economic growth in developing countries, they can also be unhealthy, inefficient, and inequitable places to live. Most developing countries are increasingly unable to provide basic environmental infrastructure and services, whether in the megacities or in secondary urban centers. Of particular concern is the strain on natural resources brought by the increasing number of people, cars, and factories. They are generating ever greater amounts of urban wastes and emissions. They also exceed the capacity of regulatory authorities to control them and of nature to assimilate them. The environmental consequences are translated into direct negative impacts on human health, the quality of life, the productivity of the city, and the surrounding ecosystems. Environmental degradation threatens the long tenn availability and quality of natural resources critical to economic growth. Cities, with their higher and growing per capita energy use for domestic, industrial, and transport purpose also contribute a disproportionate share of the emission leading to global warming and acid rain. An important priority is to develop strategic approaches for managing the urban environment. The design of appropriate and lasting strategic responses requires first an understanding of the underlying causes of urban environmental deterioration, it is necessary that longer tenn objectives should be set for urban area to avoid irreversible ecological damage and to ensure lasting economic development. As a means to the preventive policies against the adverse effect, environmental impact assessment (EIA) serve to identify a project's possible environmental consequences early enough to allow their being taken into consideration in the decision making process for urban planning. This paper describes some considerations of EIA for urban planning-scoping, assessment process, measurement and prediction of impacts, pollution controls and supervision, and system planning for environmental preservation.

• 한국IT서비스학회지
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• 제19권2호
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• pp.23-35
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• 2020

The development of digital technology is changing the paradigm of the healthcare industry to preventive and consumer-oriented. The combination of the ICT industry and the bio-healthcare industry is emerging as a core industry in the era of the Fourth Industrial Revolution. The Korean government has also selected the bio-healthcare industry as one of the three key future development industries. In May, the government announced its bio-health industry innovation strategy and set a goal of 300,000 employees. Therefore, analyzing the effects of employment on the related industries of the digital bio-healthcare industry is very important for the establishment of future industrial and technology development policies. The research method restructures the integrated classification of 32 industries into 34, including the digital bio-healthcare industry, using the classification criteria of the government and professional institutions, and then reorganizes the digital bio-healthcare industry into eight industries classified as one industry group. The analysis data was taken from the Bank of Korea's 2019 data. Various trigger coefficients and ripple effects coefficients were rewritten using the analysis method of the Input-output Statistics. The analysis of the results compares the employment-induced effects of the digital bio-healthcare industry and the ripple effects of related industries in production, investment and value-added. In addition, in terms of investment effect, the effects of in-house and related industries were compared. It is hoped that the results of this study will be used to establish employment and industrial policies.

• 한국응급구조학회지
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• 제20권2호
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• pp.37-49
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• 2016

Purpose: This study investigated the current status of post-traumatic stress and related factors among safety managers in Korea National Parks. Methods: The study subjects were 109 safety managers working in Korea National Parks. General characteristics, job-related characteristics, experience of traumatic events and post-traumatic stress were collected by self-reported questionnaires through the mail. The associated factors with post-traumatic stress was analyzed by t-test, ANOVA and multiple linear regression. Results: Overall score of post-traumatic stress was $10.32{\pm}11.37$ and 12.8% was the high-risk group of post-traumatic stress disorder. In simple analysis, score of post-traumatic stress was associated with drinking frequency, disease history, duration of career, delay of rescue, provided the break, rest space and the number of experiences of traumatic events. Finally, the score of post-traumatic stress was significantly higher in subjects who experienced 3 (B=9.141, SE=3.538) or more than 4 (B=11.367, SE=3.063) traumatic events compared to subjects without experience of traumatic event. Conclusion: The score of post-traumatic stress was $10.32{\pm}11.37$ and 12.8% was the high-risk group among safety managers in Korea National Parks. Post-traumatic stress was associated with the experience of traumatic events. Management of safety managers after mobilization or experience of traumatic events will be helpful to decrease of post-traumatic stress.

• 한국IT서비스학회지
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• 제20권6호
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• pp.45-62
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• 2021

After the COVID-19 outbreak in 2019, the spread of COVID-19 has not been easily caught despite preventive measures in each country. The spread of COVID-19 has hit the world, especially in the economic and tourism sectors. Countries around the world are easing restrictions on the movement of vaccinated people in preparation for the post-corona era. Under the name of "Vaccine Passport," "Vaccination Certificate," and "Digital Health Pass," vaccination measures are being implemented to allow vaccination recipients to use multi-use facilities. However, there is no international agreement on the movement of countries, and each country has its own immigration policy. In order to return to pre-corona daily life, global agreements must be reached from the movement of vaccinated people between countries, and standards and implementation methods must be determined. This study focuses on the implementation and utilization of vaccination certificates suitable for the COVID-19 era. We will look at the spread of COVID-19 and its international response policies. In the case of COVID-19, we will investigate why vaccination certificate installation should be standardized and how far the current standardization has been discussed, and discuss the characteristics of vaccination certificate installation and considerations. In order for the immunization certificate discussed in the previous chapter to be recognized internationally, institutional and technical considerations are identified and security factors that may occur in each implementation are also presented. Finally, the international recognition case of vaccination certificate is discussed, and the method of installation and utilization of vaccination certificate is proposed. This paper can be used as a policy because of its timeliness in studying the standards of vaccination certificates and considerations for international recognition to restore movement between countries in the spread of COVID-19. In addition, if other infectious diseases occur in the future or similar cases where movement between countries is restricted, it can be used as a reference to support the movement of verified people.