• Journal of Korean Academy of Nursing
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• v.50 no.5
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• pp.658-670
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• 2020

Purpose: This study aimed to identify the predictors of blood and body fluid exposure (BBFE) in multifaceted individual (sleep disturbance and fatigue), occupational (occupational stress), and organizational (hospital safety climate) factors, as well as infection prevention behavior. We also aimed to test the mediating effect of infection prevention behavior in relation to multifaceted factors and the frequency of BBFE. Methods: This study was based on a secondary data analysis, using data of 246 nurses from the Shift Work Nurses' Health and Turnover study. Based on the characteristics of zero-inflated and over-dispersed count data of frequencies of BBFE, the data were analyzed to calculate zero-inflated negative binomial regression within a generalized linear model and to test the mediating effect using SPSS 25.0, Stata 14.1, and PROCESS macro. Results: We found that the frequency of BBFE increased in subjects with disturbed sleep (IRR = 1.87, p = .049), and the probability of non-BBFE increased in subjects showing higher infection prevention behavior (IRR = 15.05, p = .006) and a hospital safety climate (IRR = 28.46, p = .018). We also found that infection prevention behavior had mediating effects on the occupational stress-BBFE and hospital safety climate-BBFE relationships. Conclusion: Sleep disturbance is an important risk factor related to frequency of BBFE, whereas preventive factors are infection prevention behavior and hospital safety climate. We suggest individual and systemic efforts to improve sleep, occupational stress, and hospital safety climate to prevent BBFE occurrence.

• Journal of the Korean Society of School Health
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• v.35 no.3
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• pp.75-83
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• 2022

Purpose: This study aimed to identify factors affecting COVID-19 infection prevention behaviors among teachers and administrative staff of elementary schools. Methods: A total of 204 participants, who were elementary school teachers and administrative staff, completed a pack of self-report questionnaires. The variables were COVID-19-related knowledge and COVID-19 infection prevention behaviors. The collected data were analyzed using descriptive statistics, t-test, 𝑥², Pearson's correlation coefficient, and multiple regression. Results: The participants' COVID-19-related knowledge was 3.67±0.85 and their COVID-19 prevention behaviors were 4.60±0.36. COVID-19 prevention behaviors had a positive relationship (r=.15, p=.031) with COVID-19-related knowledge. Factors affecting COVID-19 prevention behaviors were occupation (administrative staff), age, sex (male), COVID-19-related knowledge, and subjective health (good). Conclusion: It is expected that findings of the study will be used as essential data for developing strategies promoting school health. Considering the results, there is a need to create effective interventions that can increase COVID-19 infection prevention behaviors and COVID-19-related knowledge of teachers and administrative staff of elementary schools.

• The Korean Journal of Emergency Medical Services
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• v.26 no.1
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• pp.57-70
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• 2022

Purpose: The purpose of this study was to investigate the effect of coronavirus disease-19 (COVID-19) knowledge, anxiety, and psychosocial well-being on the infection prevention behavior of college students in health care. Methods: This study is a descriptive survey research. A total of 301 college students at four health care departments in three regions were surveyed using a structured questionnaire from February 10 to February 16, 2022. The collected data were analyzed using descriptive statistics, independent t-test, and one-way ANOVA. Pearson correlation coefficients and multiple regression analyses were done using SPSS ver. 18.0. Results: Knowledge on COVID-19 was significantly dependent on a family history of chronic disease (p=.049). Anxiety was significantly dependent on test of COVID-19 (p=.040). Gender (p=.049), perceived physical and mental health status (p=.000), and chronic disease (p=.000) had significant effects on infection prevention behavior. When the level of anxiety was higher, the infection prevention behavior was also higher (p=.000) and the psychosocial well-being was improved (p=.017). Stepwise multiple regression analysis revealed that anxiety significantly improved the infection prevention behavior (𝛽=.396, p<.001) and psychosocial well-being (𝛽=-.139, p=.008), which accounts for 18.5% (F=22.444, p<.001) of the variance. Conclusion: In order to prevent infectious diseases such as COVID-19 and its spread, measures to prevent infection and improve the psychosocial well-being should also be sought.

• Parasites, Hosts and Diseases
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• v.53 no.6
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• pp.777-783
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• 2015

The nitric oxide (NO) formation and intrinsic nitrosation may be involved in the possible mechanisms of liver fluke-associated carcinogenesis. We still do not know much about the responses of inducible NO synthase (iNOS) induced by Clonorchis sinensis infection. This study was conducted to explore the pathological lesions and iNOS expressions in the liver of mice with different infection intensity levels of C. sinensis. Extensive periductal inflammatory cell infiltration, bile duct hyperplasia, and fibrosis were commonly observed during the infection. The different pathological responses in liver tissues strongly correlated with the infection intensity of C. sinensis. Massive acute spotty necrosis occurred in the liver parenchyma after a severe infection. The iNOS activity in liver tissues increased, and iNOS-expressing cells with morphological differences were observed after a moderate or severe infection. The iNOS-expressing cells in liver tissues had multiple origins.

• The Journal of the Convergence on Culture Technology
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• v.8 no.2
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• pp.131-138
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• 2022

This study is a descriptive study to investigate factors affecting the level of performance of COVID-19 infection prevention activities among nurses. The participants were 190 nurses at a tertiary hospital located in Daejeon city and data collection was performed during March, 2021. The results showed that the factors affecting the level of performance of infection prevention activities were age(β=.25, p=.008), working unit(β=.15, p=.046), and hospital safety climate(β=.17, p=.025). Therefore, in order to improve the level of performance of infection prevention activities among hospital nurses, education and policy to establish a hospital safety climate should be implemented.

• Journal of Convergence for Information Technology
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• v.7 no.4
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• pp.19-26
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• 2017

The purpose of this study was to examine the knowledge of nursing students on methicillin-resistant Staphylococcus aureus (MRSA), and the compliance level of infection prevention during their clinical practice. The data was collected using a questionnaire from the 234 senior nursing students with previous clinical practice experience from October $14^{th}$ to November $30^{th}$, 2016. According to the result, the mean MRSA knowledge score was 52.0 points out of 100 and the compliance level for MRSA infection prevention was 89.41 points out of 100. As for the factors affecting compliance of MRSA infection prevention, education of MRSA and awareness about the possibility of MRSA infection during the clinical practice were significant. In order to promote compliance of MRSA infection prevention, it is necessary to develop educational programs centering on the contents applicable to clinical practice, including awareness on possible infection.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.9
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• pp.4953-4960
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• 2013

Primary liver cancer is one of the most common cancers at the global level, accounting for half of all cancers in some undeveloped countries. This disease tends to occur in livers damaged through alcohol abuse, or chronic infection with hepatitis B and C, on a background of cirrhosis. Various cancer-causing substances are associated with primary liver cancer, including certain pesticides and such chemicals as vinyl chloride and arsenic. The strong association between HBV infection and liver cancer is well documented in epidemiological studies. It is generally acknowledged that the virus is involved through long term chronic infection, frequently associated with cirrhosis, suggesting a nonspecific mechanism triggered by the immune response. Chronic inflammation of liver, continuous cell death, abnormal cell growth, would increase the occurrence rate of genetic alterations and risk of disease. However, the statistics indicated that only about one fifth of HBV carries would develop HCC in lifetime, suggesting that individual variation in genome would also influence the susceptibility of HCC. The goal of this review is to highlight present level of knowledge on the role of viral infection and genetic variation in the development of liver cancer.

• Journal of the Korean Applied Science and Technology
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• v.41 no.2
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• pp.188-198
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• 2024

This study was conducted to understand the level of compliance and influencing factors to respiratory infection prevention among the college students who experienced the COVID-19 pandemic. An online survey was conducted on 200 college students from December 15, 2023 to January 5, 2024, and the data of 199 people who responded faithfully were analyzed using descriptive statistics, t-test, ANOVA, and multiple regression through SPSS 18.0. According to the result, the compliance level of respiratory infection prevention was 32.95±6.05 points on average out of 48 points. The general characteristics, which showed differences in the compliance level of respiratory infection prevention, and the characteristics related to respiratory infections were identified to be major (t=-2.59, p=.010), education on respiratory infection prevention (t=1.99, p=.048), influenza vaccination of the year (t=-2.10, p=.037), COVID-19 vaccination of the year (t=3.56, p<.001), and mask wearing in crowded places (t=4.96, p<.001). As for the factors influencing the compliance to respiratory infection prevention, major (β=0.31, p<.001), influenza vaccination of the year (β=-0.15, p=.046), and mask wearing in a crowded places (β=-0.31, p<.001) were identified as a significant variable in the multiple regression analysis. In conclusion, since respiratory infections continue to occur even after the termination of COVID-19 epidemic, it is necessary to make efforts to promote compliance to respiratory infection prevention practice, and it is expected that the factors identified in this study can be used as the basic data when developing a respiratory infection prevention program targeting college students.

• Journal of Korean Public Health Nursing
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• v.36 no.3
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• pp.417-430
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• 2022

Purpose: The purpose of this study was to develop a respiratory infection prevention program for the rural elderly in the post-coronavirus disease 2019 (COVID-19) era. Methods: The Delphi method was used to validate the contents of the program. Two rounds of Delphi surveys and one individual interview were conducted on four subjects and 16 categories with nine experts. Content validity was calculated using the content validity ratio (CVR) and coefficient of variation (CV). Results: This study verified the content validity of the existing program components, such as respiratory infection prevention characteristics, cough etiquette, correct hand washing, oral hygiene, correct tooth brushing, and exercise by walking. The study comprised 28 categories covering seven subjects, including the provision of knowledge and information about COVID-19, environmental management for respiratory infection prevention, and exercise training for immunity enhancement. Conclusion: This Delphi study examined the respiratory infection prevention program that was redesigned for the post-COVID-19 era and confirmed the validity of the educational contents. The findings of this study suggest that the program can be used practically for the prevention of respiratory infection among the rural elderly.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.25 no.3
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• pp.210-219
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• 2018

Purpose: The purpose of this study was to investigate the effects of emergency setting visitors' knowledge and behavior patterns in relation to prevention of respiratory tract infections. Methods: A descriptive survey was used. The participants were visitors to the emergency service in 'D' general hospital in 'D' city, and the data were collected from July 1 to September 1, 2016. The collected data were analyzed using frequency analysis, t-test, ANOVA, $Scheff{\acute{e}}$ test, Pearson correlation coefficients, and multiple regression analysis. Results: Factors influencing prevention of respiratory tract infections were visitors' education level, methods of dissemination of prevention information, and participants' knowledge with regard to preventive methods. The explanatory power was found to be 35% in the regression model. Conclusion: The findings indicate that visitors' education level, knowledge of infection prevention, and the dissemination of information regarding infection prevention by the hospital play an important role in the prevention of respiratory tract infections in emergency services in the hospital. These results highlight the need for a customized education program for prevention of respiratory tract infections in emergency settings. Programs should take into consideration the educational background of visitors, and provide them with appropriate information regarding infection prevention.