• 제목/요약/키워드: Prevention of Infectious Diseases

검색결과 404건 처리시간 0.026초

어린이집 원장의 감염병 예방 교육요구도 및 자기효능감 (Educational Needs and Self-efficacy for Prevention of Infectious Diseases of Day Care Center Administrators)

  • 유선영;주은경
    • 디지털융복합연구
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    • 제20권5호
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    • pp.909-918
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    • 2022
  • 본 연구는 어린이집 원장을 대상으로 감염병 예방 교육요구도, 자기효능감을 파악하고 감염병 예방 자기효능감에 영향을 미치는 요인을 파악하고자 시행되었다. 연구는 G, J, S시 소재 어린이집 원장 172명을 대상으로 설문지를 이용하여 진행하였다. 수집된 자료는 SPSS 24.0 프로그램을 이용하여 기술통계, t-test, ANOVA, Pearson's correlation coefficient, Multiple regression analysis로 분석하였다. 연구 결과, 감염병 예방 교육요구도는 손 씻기 방법 및 시기, 세척과 소독 방법이 높았고, 감염병 예방 자기효능감은 영유아 손 씻기 교육과 시기가 가장 높았다. 감염병 예방 교육요구도와 자기효능감(r=.528, p<.001) 간에는 양의 상관관계가 있는 것으로 나타났다. 감염병 예방 자기효능감에 영향을 미치는 유의한 요인은 감염병 예방 교육요구도(β=.53, p<.001), 감염병 예방 교육의 경험(β=.25, p<.001)로 나타났다. 이러한 연구 결과는 어린이집 원장에 대한 감염병 예방에 대한 교육 요구를 충족시킬 수 있는 프로그램 개발이 필요하다는 것을 보여준다. 이러한 교육을 통해 어린이집 원장의 감염병 예방에 대한 자기효능감이 향상될 것이다.

Construction of Luminescence- and Fluorescence-Tagged Burkholderia pseudomallei for Pathogen Tracking in a Mouse Model

  • Shin, Yong-Woo;Park, Deok Bum;Choi, Myung-Min;Chun, Jeong-Hoon;Seong, Baik-Lin;Rhie, Gi-Eun
    • Journal of Microbiology and Biotechnology
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    • 제28권3호
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    • pp.498-502
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    • 2018
  • Molecular imaging is a powerful method for tracking various infectious disease-causing pathogens in host organisms. Currently, a dual molecular imaging method that can provide temporal and spatial information on infected hosts at the organism, organ, tissue, and cellular levels simultaneously has not been reported for Burkholderia pseudomallei, a high-risk pathogen that causes melioidosis. In this study, we have established an experimental method that provides spatiotemporal information on infected hosts using luminescent and fluorescent dual-labeled B. pseudomallei. Using this method, we visualized B. pseudomallei infection at the organism, organ, and tissue levels in a BALB/c mouse model by detecting its luminescence and fluorescence. The infection of B. pseudomallei at the cellular level was also visualized by its emitted fluorescence in infected macrophage cells. This method could be an extremely useful and applicable tool to study the pathogenesis of B. pseudomallei-related infectious diseases.

Diagnosis and Molecular Analysis on Imported Plasmodium ovale curtisi and P. ovale wallikeri Malaria Cases from West and South Africa during 2013-2016

  • Shin, Hyun-Il;Ku, Bora;Kim, Yu Jung;Kim, Tae Yun;Cho, Shin-Hyeong;Lee, Sang-Eun
    • Parasites, Hosts and Diseases
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    • 제58권1호
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    • pp.61-65
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    • 2020
  • Majority of the imported malaria cases in Korea is attributed to Plasmodium falciparum and P. vivax infections, whereas P. malariae and P. ovale infections are very rare. Falciparum and ovale malaria are mostly imported from Africa, while most of the vivax malaria cases are imported from Southeast Asia. Here, we report 6 Korean imported ovale malaria cases (4 males and 2 females) who had visited in Africa during 2013-2016. These subjects were diagnosed with P. ovale based on microscopic findings, Plasmodium species-specific nested-PCR, and phylogenetic clade using 18S rRNA gene sequences. We identified 2 P. ovale subtypes, 1 P. ovale curtisi (classic type) and 5 P. ovale wallikeri (variant type). All patients were treated with chloroquine and primaquine, and no relapse or recrudescence was reported for 1 year after treatment. With increase of travelers to the countries where existing Plasmodium species, the risk of Plasmodium infection is also increasing. Molecular monitoring for imported malaria parasites should be rigorously and continuously performed to enable diagnosis and certification of Plasmodium spp.

Improving Pneumovirus Isolation Using a Centrifugation and AZD1480 Combined Method

  • Lee, Hansaem;Woo, Hye-Min;Kim, Kisoon;Park, Sehee;Park, Man-Seong;Kim, Sung Soon;Kim, You-Jin
    • Journal of Microbiology and Biotechnology
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    • 제29권12호
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    • pp.2006-2013
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    • 2019
  • The isolation of respiratory viruses, especially from clinical specimens, often shows poor efficiency with classical cell culture methods. The lack of suitable methods to generate virus particles inhibits the development of diagnostic assays, treatments, and vaccines. We compared three inoculation methods, classical cell culture, the addition of a JAK2 inhibitor AZD1480, and centrifugation-enhanced inoculation (CEI), to replicate human respiratory syncytial virus (HRSV) and human metapneumovirus (HMPV). In addition, a combined method using AZD1480 treatment and CEI was used on throat swabs to verify that this method could increase virus isolation efficiency from human clinical specimens. Both CEI and AZD1480 treatment increased HRSV and HMPV genome replication. Also, the combined method using CEI and AZD1480 treatment enhanced virus proliferation synergistically. The combined method is particularly suited for the isolation of interferon-sensitive or slowly growing viruses from human clinical specimens.

제주특별자치도 코로나19 대응 보건인력 대상 설문조사 연구 (COVID-19 response survey study on health personnel in Jeju Special Self-governing Province)

  • 강남훈;배종면
    • Journal of Medicine and Life Science
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    • 제21권1호
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    • pp.1-10
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    • 2024
  • The purpose of this study is to determine the issues of supplementation and improvement to prepare for the outbreak of new infectious diseases such as new variants of coronavirus disease 2019 (COVID-19) to guide work for a strategic new response to infectious disease. Public officials of Jeju Special Self-governing Province and health personnel responding to COVID-19, working at six public health centers in Jeju-do region were administered a survey about additional preparations to be made in the future, based on the period when COVID-19 was treated legally as a first-class infectious disease. Frequency analysis was conducted on the collected data. The Likert 5-point scale and Kruskal-Wallis test were used to compare the scores for effective response to emerging infectious diseases according to demographics. Among the important factors identified for effective response to new infectious diseases, 'facilitation of cooperation with public institutions' and 'facilitation of cooperation with private institutions' had the highest scores. In the future, when a patient presents with a new infectious disease, the step that needs to be supplemented in each phase of the public health center's response is 'immediate response team operation'. Further, public health centers responded that 'expansion of dedicated personnel related to infectious diseases' needs to be improved to respond to new infectious diseases. Along with the results of this study, considering the difficulties experienced by health personnel responding to new infectious diseases in preparation for future outbreaks of new infectious diseases, and to respond effectively, detailed and clear guidelines for responding to quarantine of patients of new infectious diseases will be needed.

Infectious diseases in children and adolescents in the Republic of Korea: Past & recent status

  • Kim, Jong-Hyun
    • Clinical and Experimental Pediatrics
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    • 제54권12호
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    • pp.489-500
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    • 2011
  • Compared to the past decades, in recent decades, environmental and hygienic conditions in the Republic of Korea have improved along with socioeconomic developments, and the incidence of most infectious diseases, especially vaccine-preventable diseases, has greatly decreased due to active immunization with the developed level of health care. However, the incidence of some diseases has been increasing, and new diseases have been emerging. To cope with such changes actively, the government put the "Law for Control and Prevention of Infectious Diseases" into effect; this law was entirely revised on December 30, 2010. In this report, I review the past and recent status of infectious diseases in the Republic of Korea, following the introduction of this law, on the basis of data in the "National Notifiable Disease Surveillance System", which had been accumulated between the years 1960 and 2010.

Lentivirus-mediated Silencing of Rhomboid Domain Containing 1 Suppresses Tumor Growth and Induces Apoptosis in Hepatoma HepG2 Cells

  • Liu, Xue-Ni;Tang, Zheng-Hao;Zhang, Yi;Pan, Qing-Chun;Chen, Xiao-Hua;Yu, Yong-Sheng;Zang, Guo-Qing
    • Asian Pacific Journal of Cancer Prevention
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    • 제14권1호
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    • pp.5-9
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    • 2013
  • Rhomboids were identified as the first intramembrane serine proteases about 10 years ago. Since then, the study of the rhomboid protease family has blossomed. Rhomboid domain containing 1 (RHBDD1), highly-expressed in human testis, contains a rhomboid domain with unknown function. In the present study, we tested the hypothesis that RHBDD1 was associated with proliferation and apoptosis in hepatocellular carcinoma using recombinant lentivirus-mediated silencing of RHBDD1 in HepG2 cells. Our results showed that down-regulation of RHBDD1 mRNA levels markedly suppressed proliferation and colony formation capacity of HepG2 human hepatoma cancer cells in vitro, and induced cell cycle arrest. We also found that RHBDD1 silencing could obviously trigger HepG2 cell apoptosis. In summary, it was demonstrated that RHBDD1 might be a positive regulator for proliferative and apoptotic characteristics of hepatocellular carcinoma.

수인성 전염병의 현황 및 효율적 관리 (Present status and effective control measure of water-borne infectious diseases in Korea)

  • 김호훈
    • 환경위생공학
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    • 제9권2호
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    • pp.41-49
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    • 1994
  • Water- borne infectious diseases can be acquired by contact with contaminated water or by ingestion of contaminated water. There are many water- borne infectious agents such as bacteria, virus, and parasite. Among many of water- borne infectious diseases, health authorities of Korean government has particularly intensified to prevent and control typhoid fever(class I ), shigellosis(class I ), cholera(class I ), paratyphoid fever(class I), amebiasis(class II ) and leptospirosis(euivalent to class II ) under the communicable disease control law. Water- borne disease Prevention and control guideline itself has been also well provided by the health authorities. However, in practical public health point of view, there are still many problems remained to be solved out; no prospective investigation project to survey water borne infectious diseases under the national disease prevention and control programmes, incredible statistic data of annual notifiable disease report frequent appearance and varieties of drug resistance water- borne infectious agents, little cooperation and information- exchange system in between the related government authorities( the health authorities, the environment sanitation authorities and the food hygiene authorities) which should be closely collaborated, lack of health consciousness of the people, necessity of evaluation and Hndification on to the outcomes of performed health activities and programmes, neglect activities for water quality investigation, shortage of expertise and human resources in the related field, and poor investment of the government budget to develope and improve public health and sanitation field. In order to prevent and control water- borne infectious diseases effectively, it is emphasized that all the above indicated should be considered and performed to improve under the national health and sanitation development programmes.

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국내 가금 농장에서 야생조류 침입 억제 장치를 이용한 야생조류 출현율 조사 및 평가 (Investigation and evaluation of appearance ratio using wildbird intrusion prevention device in domestic fowl farms)

  • 김용식;김윤지;나은지;이숙영;엄재구
    • 한국동물위생학회지
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    • 제43권3호
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    • pp.167-171
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    • 2020
  • The epidemiological investigation of outbreak in korea confirmed that the inflow of avian influenza (AI) is related to the migration of migratory birds. In this study, avian repellents instrument were implemented and developed using the visual effects of lasers in accordance with the situation of small domestic fowl farms, and monitoring cameras were installed around each instrument to investigate the frequency of wild birds appearing and evaluate the performance of the instrument. Observation showed that the appreance ratio was reduced by 95%, and no significant reduction in the intrusion prevention effect by adaptation was observed on all fowl farms. In conclusion, it is expected that the outbreak of wild bird-borne infectious diseases such as avian influenza will be decreased if the device is installed on domestic fowl farms.

노인의 감염병 예방을 위한 관리 및 지식도 (Management and Knowledge for the Prevention of Infectious Diseases in the elderly)

  • 강경희;김광환;김용하
    • 디지털융복합연구
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    • 제20권5호
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    • pp.713-720
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    • 2022
  • 본 연구의 목적은 노인의 감염병 예방을 위한 개인위생실천정도, 감염에 대한 지각된 위험, 감염병에 대한 지식 및 중요도를 조사하여 노인 대상 감염병 예방을 위한 교육프로그램 개발을 위한 기초자료를 제공하기 위함이다. 2021년 10월 한 달 동안 구조화된 설문지를 이용하여 한국갤럽을 통해 일대일 개별 면접조사로 65세 이상 노인 110명 조사하였다. 조사 자료는 IBM SPSS statistics 25.0 program을 이용하여 분석하였다. Borich 요구도 공식으로 환산하여 중요도와 지식정도를 합산하여 순위를 분석한 결과, 1순위는 감염병의 전파경로, 2순위는 감염병의 예방 방법, 3순위는 감염병의 치료 방법, 4순위는 감염병 의심 및 확진 시 처리절차, 5순위는 감염병의 주요 증상으로 조사되었다. 본 연구결과는 감염병 예방 및 관리에 대한 요구도를 반영한 노인 대상 교육프로그램 개발에 기초자료로 제공함으로 대상자에게 적절한 정보제공을 통한 감염예방실천 향상에 기여할 수 있을 것이다.