• Journal of fish pathology
• /
• v.32 no.1
• /
• pp.29-35
• /
• 2019

A monitoring was performed to survey the mortalities that had occurred in the aquaculture farms of olive flounder (Paralichthys olivaceus) in South Korea from 2015 to 2017. The indirect inquiry for entire farms and the sample survey for selected farms were carried out. The aquatic organism disease inspectors, who have a national license for the diagnosis and prevention of aquatic organism diseases and a have close relationship with the farms, investigated the rates and causes of mortalities according to the standard manual. The mortality rate by sample survey of farms in 2015, 2016, and 2017 were 24.78% (Chunnam: 17.86%, Jeju: 28.69), 30.19% (Chunnam: 24.45%, Jeju: 32.65), and 21.59% (Chunnam: 10.57%, Jeju: 26.00%), respectively. The major cause of mortality was scuticociliatosis, and the mortality caused by viral hemorrhagic septicemia and emaciation disease (Jeju) were also high. Our results can contribute to effective establishment prevention of epidemics system and acquired status as a disease-cleansing country.

• The Journal of The Korea Institute of Intelligent Transport Systems
• /
• v.21 no.1
• /
• pp.209-220
• /
• 2022

With the worldwide spread of African swine fever, interest in livestock epidemics has increased. Livestock transport vehicles are the main cause of the spread of livestock epidemics, but there are no empirical quarantine procedures and standards related to the mobility of livestock transport vehicles in South Korea. This study extracted the trajectory of livestock-related vehicles using the facility-visit history data from the Korea Animal Health Integrated System and the DTG (Digital Tachograph) data from the Korea Transportation Safety Authority. The results are presented as exposure indices aggregating the link-time occupancy of each vehicle. As a result, 274,519 livestock-related vehicle trajectories were extracted, and the exposure values by link and zone were derived quantitatively. This study highlights the need for prior monitoring of livestock transport vehicles and the establishment of post-disaster prevention policies.

• Pediatric Infection and Vaccine
• /
• v.9 no.2
• /
• pp.201-207
• /
• 2002

Purpose : We analyzed clinical features and causal viruses of acute lower respiratory tract infections(LRTIs) in order to improve the management of these infections. Methods : From end of April to early May 2001, amongst 30 children at a local institute for children's adoption and welfare, 13 were admitted to the hospital with the diagnostic impression of acute LRTIs. Nasopharyngeal aspirates were sent in Seoul National University Hospital for viral culture of respiratory syncytial virus(RSV), adenovirus, parainfluenza virus. Results : One or more viral agents were identified in 4 cases(30.7%) : were RSV(15.4%), adenovirus(7.7%), and a mix of these two viruses(7.7%). Initial symptoms were fever(69%), cough(100%), tachypnea(54%), chest retraction(69%), rale(85%) and wheezing(15%). Leukocytosis was noted in 23%, CRP increased more than 10 mg/L in 46%. Chest X-ray abnormalities were 69%. Conclusion : Although viruses were identified in 30.7%, further studies should be made for prevention and treatment of acute viral LRTIs.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.11 no.1
• /
• pp.335-340
• /
• 2010

In accordance with the increasing possibility that the new and reoccurring epidemics continuously appearing abroad flow into Korea, it is very important to evaluate the efficiency of quarantine management projects of National Quarantine Station. This study adopted the pairwise comparison approach using the analytical hierarchy process(AHP) that has been recognized with its scientific adequacy for allocating the weight, the relative importance of evaluation components. AHP technique is evaluated to be distinguished in measuring the impact by making hierarchy of, simplifying and systemizing the complicated multi-criteria decision making problems. The weights by evaluation indexes were 0.2 in the organization evaluation field and 0.8 in the service and program field. The quarantine business showed the highest value, 0.45, in the service and program field. The indexes were classified into the upper category (organization evaluation field, service and program evaluation field) and lower category (input/process/result/quarantine field, inspection field, hygiene management field, pathogenic organ investigation and monitoring field, epidemics prevention promotion/education field). The evaluation indexes that were finally selected were applied to the actual businesses in National Quarantine Station. Next, the minimum evaluation indexes were selected and so the evaluation system on the businesses in National Quarantine Station was more systemized.

• Clinical and Experimental Pediatrics
• /
• v.53 no.5
• /
• pp.639-643
• /
• 2010

Purpose: Hand-foot-mouth disease (HFMD) is a common viral illness in children, which is usually mild and self-limiting. However, in recent epidemics of HFMD in Asia, enterovirus 71 (EV71) has been recognized as a causative agent with severe neurological symptoms with or without cardiopulmonary involvement. HFMD was epidemic in Korea in the spring of 2009. Severe cases with complications including death have been reported. The clinical characteristics in children with neurologic manifestations of EV71 were studied in Ewha Womans University Mokdong Hospital. Methods: Examinations for EV71 were performed from the stools, respiratory secretion or CSF of children who presented neurologic symptoms associated with HFMD by realtime PCR. Clinical and radiologic data of the patients were collected and analyzed. Results: EV71 was isolated from the stool of 16 patients but not from respiratory secretion or CSF. Among the 16 patients, meningitis (n=10) was the most common manifestation, followed by Guillain-Barre syndrome (n=3), meningoencephalitis (n=2), poliomyelitis-like paralytic disease (n=1), and myoclonus (n=1). Gene analysis showed that most of them were caused by EV71 subgenotype C4a, which was prevalent in China in 2008. Conclusion: Because EV71 causes severe complications and death in children, a surveillance system to predict upcoming outbreaks should be established and maintained and adequate public health measures are needed to control disease.

• Journal of Korean Academy of Nursing
• /
• v.4 no.1
• /
• pp.107-120
• /
• 1974

Necessity and purpose of this study: In a large number of countries it has been founded that children′s domestic accidents are at great risk year by year In the United States, they publish detailed accident statistics at regular intervals. In Korea. there have been just a few studies on Accidents-At-Home of preschool children. But it can not be said that there have been any systematic statistics about this area. and any study accounting for the relations of home accidents and preschool: children in detail, Therefore, the purpose of this thesis was focused on the inquire of these relations so as to make a little contribution to Korean preschool children′s health and security measures. So, the detail-purposes are to study following questions and to testify following hypothesis. Prob. 1. What the types of accidents of Preschool children, where the place accidents occurred\ulcorner Prob. 2. What the cause of accidents and, the main factors of the cause\ulcorner Prob. 3. How about the number of their children. the disparity of age among their children and mother′s age in each case of accidents\ulcorner hypothesis 1. There will be differences in the density of protection of parents according to the number of their children. hypothesis 2, There will be differences in accident-types and first-aid methods according to parents socio-economic background. Method; This study employed the interviewing survey method, in which 130 preschool children ware random.sampled, who visit hospital to have medical care. These children (from 1 to 6 years olds) were selected at the emergency room of five hospitals in Seoul (Hosp: Severance, Woosok, Medical Center, Hanyang Medical College Hospital and Seoul Medical Col1age Hospital during study-period (from Aug. to Oct, 1973). Four head nurses in above Hospitals were employed as accident members for this study. Concerning research analysis, the method of hypothesis verifying is used. Conclusion: As two American experts on this subject. Dr, Raymond Neuter and Mr. Ross Mc Garland have drawn attention to "minor epidemics of accidents" that could be avoided by fairly simple measures. preschool children′s accidents could be avoided by parents fair attentions. In other words, one of the most common causes of preschool children′s accidents derived from their parent′s inattention. Therefore, one important task on this subject is to instruct the parents fairly about the children′s accidents. Many accidents could be avoided by the exorcist of a little self-discipline. Also, as much the prevention of accidents is important, as the first-aid Is Important and necessary at the case of the accidents. So, the methods of proper first-aid treatment must be emphasized, and must be taught in school, especially in girls school. And there could be other means available for prevention of accidents. Firstly, the public authorities can take legal measures. More stringent safety standards can be made enforceable by law. Building materials and equipment for domestic us: ought to meat minimum safety criteria at all times. Next the public itself has to understand the seriousness of the problem, and here the dissemination of information is of great importance. All mass media should be brought into play to promote greater public awareness of the question. At last, it will be needed to obtain more detailed epidemiological data through additional surveys and statistics after this study.

• Genomics & Informatics
• /
• v.14 no.3
• /
• pp.96-103
• /
• 2016

The influenza A (H1N1) virus, also known as swine flu is a leading cause of morbidity and mortality since 2009. There is a need to explore novel anti-viral drugs for overcoming the epidemics. Traditionally, different plant extracts of garlic, ginger, kalmegh, ajwain, green tea, turmeric, menthe, tulsi, etc. have been used as hopeful source of prevention and treatment of human influenza. The H1N1 virus contains an important glycoprotein, known as neuraminidase (NA) that is mainly responsible for initiation of viral infection and is essential for the life cycle of H1N1. It is responsible for sialic acid cleavage from glycans of the infected cell. We employed amino acid sequence of H1N1 NA to predict the tertiary structure using Phyre2 server and validated using ProCheck, ProSA, ProQ, and ERRAT server. Further, the modelled structure was docked with thirteen natural compounds of plant origin using AutoDock4.2. Most of the natural compounds showed effective inhibitory activity against H1N1 NA in binding condition. This study also highlights interaction of these natural inhibitors with amino residues of NA protein. Furthermore, among 13 natural compounds, theaflavin, found in green tea, was observed to inhibit H1N1 NA proteins strongly supported by lowest docking energy. Hence, it may be of interest to consider theaflavin for further in vitro and in vivo evaluation.

• Healthcare Informatics Research
• /
• v.24 no.4
• /
• pp.300-308
• /
• 2018

Objectives: Prompt detection is a cornerstone in the control and prevention of infectious diseases. The Integrated Disease Surveillance Project of India identifies outbreaks, but it does not exactly predict outbreaks. This study was conducted to assess temporal correlation between Google Trends and Integrated Disease Surveillance Programme (IDSP) data and to determine the feasibility of using Google Trends for the prediction of outbreaks or epidemics. Methods: The Google search queries related to malaria, dengue fever, chikungunya, and enteric fever for Chandigarh union territory and Haryana state of India in 2016 were extracted and compared with presumptive form data of the IDSP. Spearman correlation and scatter plots were used to depict the statistical relationship between the two datasets. Time trend plots were constructed to assess the correlation between Google search trends and disease notification under the IDSP. Results: Temporal correlation was observed between the IDSP reporting and Google search trends. Time series analysis of the Google Trends showed strong correlation with the IDSP data with a lag of -2 to -3 weeks for chikungunya and dengue fever in Chandigarh (r > 0.80) and Haryana (r > 0.70). Malaria and enteric fever showed a lag period of -2 to -3 weeks with moderate correlation. Conclusions: Similar results were obtained when applying the results of previous studies to specific diseases, and it is considered that many other diseases should be studied at the national and sub-national levels.

• Korean Journal of Veterinary Service
• /
• v.45 no.2
• /
• pp.133-137
• /
• 2022

Lumpy skin disease (LSD) is a severe cross-border infectious disease that causes fever, skin and visceral nodules in cattle. LSD is caused by the lumpy skin disease virus (LSDV), a dsDNA virus that belongs to the genus Capripoxvirus. Although LSD has been found only in Southern Africa traditionally, in the last decade it is spreading very quickly through the Middle East and into Eastern Europe and China. It usually affects cattle and water buffalos being transmitted by blood-feeding insects. As it causes a huge economic impact, LSD is a notifiable disease by World Organisation for Animal Health, and managed as the legal infectious disease class I in Korea. Therefore, the purpose of this study was to confirm the existence of LSDV antigens or antibodies in Korean livestock. We collected 1,200 blood samples from cattle (Korean native and dairy cattle) and Korean water deer in 4 major provinces of the country, then tested the existence of LSDV antigen and antibody. None (0.0%) of the 1,200 blood samples were positive for both antigen and antibody of LSDV. To the best of our knowledge, this is the first study that examines the prevalence of LSDV in Korea. Our study aims to report the LSDV occurrence situation obtained by surveillance in Korea and provide information that may help prevention of LSD epidemics.

• Journal of The Korean Society of Agricultural Engineers
• /
• v.53 no.1
• /
• pp.29-36
• /
• 2011

HPAI (High pathogenic avian influenza) which is a disease legally designated as an epidemic generally shows rapid spread of disease resulting in high mortality rate as well as severe economic damages. Because Korea is contiguous with China and southeast Asia where HPAI have occurred frequently, there is a high risk for HPAI outbreak. A prompt treatment against epidemics is most important for prevention of disease spread. The spread of HPAI should be considered by both direct and indirect contact as well as various spread factors including airborne spread. There are high risk of rapid propagation of HPAI flowing through the air because of collective farms mostly in Korea. Field experiments for the mechanism of disease spread have limitations such as unstable weather condition and difficulties in maintaining experimental conditions. In this study, therefore, computational fluid dynamics which has been actively used for mass transfer modeling were adapted. Korea has complex terrains and many livestock farms are located in the mountain regions. GIS numerical map was used to estimate spreads of virus attached aerosol by means of designing three dimensional complicated geometry including farm location, road network, related facilities. This can be used as back data in order to take preventive measures against HPAI occurrence and spread.