• Asian Pacific Journal of Cancer Prevention
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• 제14권3호
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• pp.1989-1993
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• 2013

Background: Lung cancer is the most frequent cancer among men and second highest among women overall, including in Turkey. Cigarette smoking is the most important etiologic factor for the development of cancer in both men and women. Objective: To determine the lung cancer incidence in Northeastern Anatolia Region of Turkey with a focus on clinical properties, cancer subtypes, the relationships of tumors with cigarette smoking and radiological properties of the lesions. Materials and Methods: In a retrospective study design, 566 lung cancer cases diagnosed at the Pathology Department of Ataturk University in Erzurum over the last seven years extending from January 2006 to June 2012 were investigated. The results were compared with statistical analyses. Results: The most common histopathological subtype of primary bronchogenic carcinoma in our study was found to be the squamous cell carcinoma, 46.1% (261 out of 566), and the second was small cell lung carcinoma 15.7% (89 out of 566). Based on our data, an overall male predominance was noted with a male/female ratio of 6.1/1. While 296 (52.2%) of the patients were found to be smokers at the time of diagnosis, 125 (22.0%) were nonsmokers and 145 (25.6%) were ex-smokers. Smoking status was found to have a strong correlation with primary lung cancer (p<0.05), and there were significant differences between males and females (p<0.001). Conclusion: Although relative prominence of subtypes of lung cancers differ between Turkish and other populations, lung cancer overall remains as an important health problem in Turkey. Our findings stress the critical need for effective cancer prevention programs such as anti-smoking campaigns.

• 융합보안논문지
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• 제16권6_2호
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• pp.99-107
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• 2016

이 연구의 목적은 Bluetooth를 활용한 자동차의 내부망 통신네트워크를 해킹공격으로부터 예방하기 위한 대응방안을 제시하기 위함이다. 이를 위해 2장에서는 자동차 통신네트워크의 정의와 내부망 통신네트워크의 종류에 대해서 살펴보았다. 3장에서는 자동차 내부망 통신네트워크 해킹위험성을 분석하기 위해 Bluetooth에 의한 해킹범죄사례를 살펴보았다. 4장에서는 본 연구의 결과로서 첫째, "자동차안전기준에 관한 규칙" 개정이 이루어져야 한다. 동법에서는 전자제어시스템의 정의 및 기준사항과 안전운행을 위한 제작 및 정비를 규정해 놓았음에도 불구하고 전자제어시스템을 대상으로 한 해킹범죄 예방 및 방어와 관련된 보안프로그램 혹은 펌웨어 등의 제작과 관련된 규정이 없는 실정이다. 둘째, 자동차의 전자제어시스템 기술의 복잡성에 기인된 자동차 통신네트워크를 보호하고자 자동차 통신네트워크 보호 법률이 신설되어야 한다.

• Asian Pacific Journal of Cancer Prevention
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• 제16권12호
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• pp.5107-5110
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• 2015

The State of Punjab has been in focus because of aperceived increasing rate of cancer. Both print and electronic media have created an impression that Punjab, especially the cotton belt of Malwa Region, has become a high incidence cancer region. Actually the increased number of cancer patients might be at least partly because of increasing population and heightened health awareness and reporting. The purpose of this study is to find out the pattern of cancer amongst patients registered in Mukh Mantri Punjab Cancer Rahat Kosh Scheme (MMPCRKS), under cancer registry at Rajindra Hospital Patiala from the various districts of Punjab. The study covers 500 cancer patients registered under MMPCRKS at Rajindra Hospital Patiala, for free cancer treatment. Information regarding age, gender, religion, method of diagnosis and affected sites was obtained. Results were analyzed statistically. Of the 500 patients, 65% were females and 35% were males. The most affected female age groups were 50-54 and 60-64; while males in the age groups of 65-69 and 60-64 had the highest risk. The leading cancers in females were breast followed by cervix and ovary where as in males they were were colon followed by esophagus and tongue. The commonest histological type was adenocarcinoma followed by squamous cell carcinoma. The increasing trend of cancer in Punjab is alarming. Since this study is a preliminary investigation, it could provide a leading role in prevention, treatment and future planning regarding cancer in Punjab.

• Asian Pacific Journal of Cancer Prevention
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• 제15권20호
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• pp.8905-8910
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• 2014

Background: Coverage of cervical pap smear test in Nepal is below general global values. One of the reasons may be that cervical cancer prevention policy of Nepal has 'Visual Inspection of Cervix with Acetic Acid' as the only screening tool. The focus of present study was to find out association of demographic factors, knowledge and attitude regarding cervical Pap smear test with its practice by women in Nepal. Materials and Methods: This cross sectional analytical observational study was conducted between February 1, 2013 and April 30, 2013. Participants were interviewed with the help of a structured questionnaire. Chi square and multivariate logistic regression tests were used to detect associations of variables with pap smear practice. Results: Chi square test showed that practice was significantly associated with knowledge about pap smear test and cervical cancer, having favourable attitude towards the test, urban residency and 36-50 years age-group. Pap smear utilization was not associated with age-at-marriage, parity and age-at-first-child-birth. Multivariate logistic regression showed favorable attitude towards pap smear test as the only variable which significantly influenced pap smear practice (p= 0.006, OR: 2.4). Conclusions: Pap smear coverage has been found to be 15.7% which is lower than global average and that for developing countries. Health education programs which are effective not only in increasing knowledge about cervical cancer and pap smear test but also effective in positively changing attitude towards the test should be organized to increase pap smear coverage.

• Asian Pacific Journal of Cancer Prevention
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• 제14권10호
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• pp.6031-6034
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• 2013

This study describes recent trends in incidence, survival and prevalence of subgroups of esophageal and gastric cancer in Linzhou city between 2003 and 2009. Data of esophageal and gastric cancer for the period of interest were extracted from the Linzhou Cancer Registry. Using information on tumor morphology or anatomical site, data were divided into six groups; esophageal squamous cell carcinoma, esophageal adenocarcinoma, other and unspecified types of esophageal cancer, and cardia, non-cardia, and unspecified anatomical site of stomach cancer. Incidence, survival and prevalence rates for each of the six cancer groups were calculated. The majority of esophageal cancers were squamous cell carcinomas (82%). Cardiac cancer was the major gastric cancer group (64%). The incidence of esophageal squamous cell carcinoma and gastric cardiac cancer increased between 2003 and 2009. Both esophageal and gastric cancer had a higher incidence in males compared with females. Overall survival was poor in all sub-groups with 1 year survival ranging from 45.9 to 65.6% and 5 year survival ranging from 14.7 to 30.5%. Prevalence of esophageal squamous cell carcinoma and gastric cardiac cancer was high (accounting for 80% overall). An increased focus on prevention and early diagnosis, especially in esophageal squamous cell carcinoma and gastric cardiac cancer, is required.

• 대한간호학회지
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• 제31권2호
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• pp.292-303
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• 2001

The purpose of the study was to find out the level of knowledge, attitude, subjective norm, social interaction, and behavioral intention of nursing students regarding AIDS. It also identified factors that predict behavioral intentions and to provide care for patients with AIDS using Theory of Reasoned Action. The subjects consisted of 117 nursing students at three universities. Data was collected with self reporting in a questionnaire of with 67 items. Data was analyzed by an SPSS pc+ program. The results were as follows; 1. The mean age of the subjects was 20.98 years. The mean score for HIV/AIDS knowledge was 24.444 out of 32. Mostly Korean students were quite knowledgeable about the basic facts and symptoms of AIDS but confused about the made of transmission such as public toilets, prevention methods, and especially infection control. 2. This study found that social interaction, attitudes and subjective norms of Korean nursing students explained the intention to care for AIDS patients. The students who had a more positive attitude toward caring for AIDS patients and those who perceived more support from their significant others for caring the AIDS patients reported a more positive intention to care for AIDS patients. 3. In stepwise multiple regression analysis, 47.58% of the variance in AIDS patient care intention was accounted for by social interaction (33.41%), attitude (9.1%), and subjective norm (5.0 %). According to the finding of this study, and social interaction are the most significant predictors of intentions. Therefore it can be suggested that a HIV/AIDS prevention program should focus on transmission modes and prevention methods, especially in infection control. AIDS education efforts aimed at nursing students should place greater emphasis on correcting these kinds of misconceptions. Nursing intenvention for reducing fear of contagion, improving perception of social interaction, fostering positive attitudes and increasing intention to care for AIDS patients should be provided for nursing students. They also recommended that nursing students be adequately prepared to care for AIDS patients because of the increasing probability that they will encounter AIDS patients. Therefore it is important that education about HIV/AIDS should be incorporated within current undergraduate curriculum.

• Molecules and Cells
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• 제41권2호
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• pp.73-82
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• 2018

Cancer preventive activities of green tea and its main constituent, (-)-epigallocatechin gallate (EGCG) have been extensively studied by scientists all over the world. Since 1983, we have studied the cancer chemopreventive effects of EGCG as well as green tea extract and underlying molecular mechanisms. The first part of this review summarizes groundbreaking topics with EGCG and green tea extract: 1) Delayed cancer onset as revealed by a 10-year prospective cohort study, 2) Prevention of colorectal adenoma recurrence by a double-blind randomized clinical phase II trial, 3) Inhibition of metastasis of B16 melanoma cells to the lungs of mice, 4) Increase in the average value of Young's moduli, i.e., cell stiffness, for human lung cancer cell lines and inhibition of cell motility and 5) Synergistic enhancement of anticancer activity against human cancer cell lines with the combination of EGCG and anticancer compounds. In the second part, we became interested in cancer stem cells (CSCs). 1) Cancer stem cells in mouse skin carcinogenesis by way of introduction, after which we discuss two subjects from our review on human CSCs reported by other investigators gathered from a search of PubMed, 2) Expression of stemness markers of human CSCs compared with their parental cells, and 3) EGCG decreases or increases the expression of mRNA and protein in human CSCs. On this point, EGCG inhibited self-renewal and expression of pluripotency-maintaining transcription factors in human CSCs. Human CSCs are thus a target for cancer prevention and treatment with EGCG and green tea catechins.

• 한국융합학회논문지
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• 제8권6호
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• pp.181-197
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• 2017

본 연구는 청소년 자살예방을 위해 국내외 자살예방 문헌들에서 주요 교육내용을 추출한 후, 이를 바탕으로 게이트키퍼 교육콘텐츠를 개발하고, 그 효과성을 검증하였다. 효과성 분석을 위해 충남 C지역아동센터를 이용하는 16명의 청소년을 대상으로 양적 조사(사전-사후 검사)와 8명을 대상으로 질적 조사(포커스 그룹)를 실시하였고, 또한 전문가를 대상으로 심층인터뷰를 실시하였다. 청소년 대상 양적 분석 결과, 자살에 관한 지식은 사전에 비해 사후에 유의미하게 증가하였으나, 공감과 자살태도는 유의미한 변화를 보이지 않았다. 포커스 그룹 조사 결과에서, 청소년들은 본 교육콘텐츠 참여 후, 자살관련 지식과 힘들어 하는 친구들에 대한 공감능력 및 인식이 향상된 것으로 나타났다. 또한 전문가 대상 심층인터뷰 결과, 본 교육콘텐츠가 청소년에 매우 친화적이고, 자살예방 지식의 확장에 기여하는 것으로 나타났다. 이를 바탕으로 자살예방 게이트키퍼 교육콘텐츠의 학교 및 지역사회 현장 적용 및 추후 연구를 위한 제언을 하였다.

• Physical Therapy Rehabilitation Science
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• 제7권4호
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• pp.197-203
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• 2018

Objective: Independent walking is the most essential prerequisite to maintain quality of life in older persons. The purpose of this review was to investigate the effect of fall prevention strategies on fall risk for type 2 diabetes mellitus (T2DM) within community-dwelling older adults aged 65 and over. Design: A systematic review and meta-analysis. Methods: PubMed and three other databases were searched up to October 31st, 2018 and randomized controlled trials (RCTs) evaluating fall prevention strategies for fall risk in persons who were 65 years of age or above with T2DM were included. The review extracted the following information from each study selected: first author's surname, published year, country, study population, type of intervention, intensity of intervention, comparison, measurement variables, additional therapy, summary of results, and mean and standard deviation from selected studies. Results: This review selected fourteen RCTs with 460 older adults with diabetes mellitus. Of the 14 studies, the types of intervention used to improve the risk of falls were strengthening (5), aerobic exercises (2), multimodal exercises (4), one virtual reality exercise (1), whole body vibration with balance exercise (1), and Tai Chi exercise (1). Seven RCTs were eligible for the meta-analysis. Therapeutic interventions were more effective than the control group for the Timed Up-and-Go test (-1.11; 95% CI, -1.82 to -0.41) and the 6-minute Walk Test (-1.89; 95% CI, -8.33 to 4.54). Conclusions: The results of the review suggest that interventions to prevent fall risk in older adults with T2DM should focus on strengthening, balance, aerobic, and multimodal exercises.

• 한국콘텐츠학회논문지
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• 제21권2호
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• pp.604-621
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• 2021

커뮤니케이션 수단으로서의 소셜미디어의 성장은 소비자가 영양학적 선택과 건강한 음식 소비를 하는 데 소셜미디어의 영향력 역시 증가시켰다. 이 연구는 소셜미디어 상에서 건강한 식습관과 관련한 메시지 목표(향상 vs. 예방)와 메시지 형식(텍스트 vs. 이미지)이 메시지 설득력에 미치는 영향력을 알아보는 데 그 목적이 있다. 연구 결과에 따르면, 향상메시지에 노출된 참가자들은 소셜미디어 메시지 형식에 따른 차이를 보이지 않았으나, 예방메시지에 노출된 참가자들은 텍스트 (vs. 이미지) 형식의 메시지에 노출되었을 때, 메시지에 대한 더 긍정적인 태도를 보였으며, 해당 메시지에 대해 더 높은 클릭 의도를 보였다. 본 연구의 결과는 소셜미디어 상 건강메시지의 형식과 메시지 목표의 적합성이 메시지 효과에 영향을 미침을 이론적으로 증명하였다. 더불어 효과적인 건강메시지 작성 및 전달 방식에 대한 실무적 지침 역시 제공하리라 예상한다.